Article ; Online: Hemostatic Resuscitation in Children.
2021 Volume 35, Issue 4, Page(s) 113–117
Abstract: Trauma is a major source of morbidity and mortality for children worldwide; life-threatening hemorrhage is a primary cause of preventable death. Essential interventions in children with life-threatening hemorrhage include hemostatic resuscitation and ... ...
| Abstract | Trauma is a major source of morbidity and mortality for children worldwide; life-threatening hemorrhage is a primary cause of preventable death. Essential interventions in children with life-threatening hemorrhage include hemostatic resuscitation and mechanical control of bleeding. Herein we review pediatric hemostatic resuscitation, a strategy that addresses both hemorrhagic shock and the coagulopathic complications described in patients with major hemorrhage. Some components of hemostatic resuscitation may include: early and aggressive resuscitation with blood products, minimizing crystalloid and hemodilution, antifibrinolytic adjuncts such as tranexamic acid, and the novel use of low-titer group O whole-blood (LTOWB) transfusion in injured children. The following selection of important publications address the current state of hemostatic resuscitation strategies in pediatric trauma patients as well as the remaining knowledge gaps and areas for further research. |
|---|---|
| MeSH term(s) | Blood Transfusion ; Child ; Hemostatics/therapeutic use ; Humans ; Resuscitation ; Shock, Hemorrhagic/therapy ; Tranexamic Acid/therapeutic use ; Wounds and Injuries/complications ; Wounds and Injuries/therapy |
| Chemical Substances | Hemostatics ; Tranexamic Acid (6T84R30KC1) |
| Language | English |
| Publishing date | 2021-08-26 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 639107-2 |
| ISSN | 1532-9496 ; 0887-7963 |
| ISSN (online) | 1532-9496 |
| ISSN | 0887-7963 |
| DOI | 10.1016/j.tmrv.2021.06.008 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 2239: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.