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  1. Article ; Online: Zero fluoroscopy approach for cardiac resynchronization therapy using left bundle branch area pacing.

    Ramos-Maqueda, Javier / Alarcón, Francisco / Cabrera-Ramos, Mercedes

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2021  Volume 65, Issue 2, Page(s) 327–328

    MeSH term(s) Humans ; Cardiac Resynchronization Therapy ; Bundle-Branch Block/diagnostic imaging ; Bundle-Branch Block/therapy ; Bundle of His ; Heart Conduction System ; Fluoroscopy ; Electrocardiography ; Treatment Outcome ; Ventricular Function, Left
    Language English
    Publishing date 2021-10-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-021-01071-2
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    Zs.A 5214: Show issues Location:
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  2. Article ; Online: Síncopes de repetición en un paciente con angina vasoespástica.

    Ramos-Maqueda, Javier / Riaño Ondiviela, Adrián / Navarro-Valverde, Cristina

    Medicina clinica

    2021  Volume 157, Issue 12, Page(s) e351–e352

    Title translation Recurrent syncope in a patient with vasospastic angina.
    MeSH term(s) Angina Pectoris, Variant/complications ; Angina Pectoris, Variant/diagnosis ; Coronary Vasospasm/complications ; Coronary Vasospasm/diagnosis ; Humans ; Recurrence ; Syncope/etiology
    Language Spanish
    Publishing date 2021-06-18
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2021.02.023
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  3. Article: Local impedance and contact force guidance to predict successful cavotricuspid isthmus ablation with a zero-fluoroscopy approach.

    Melero-Polo, Jorge / Cabrera-Ramos, Mercedes / Alfonso-Almazán, Jose Manuel / Marín-García, Isabel / Montilla-Padilla, Isabel / Ruiz-Arroyo, José Ramón / López-Rodríguez, Guillermo / Ramos-Maqueda, Javier

    Frontiers in cardiovascular medicine

    2024  Volume 10, Page(s) 1322743

    Abstract: Introduction: A new technology capable of monitoring local impedance (LI) and contact force (CF) has recently been developed. At the same time, there is growing concern regarding catheter ablation performed under fluoroscopy guidance, due to its harmful ...

    Abstract Introduction: A new technology capable of monitoring local impedance (LI) and contact force (CF) has recently been developed. At the same time, there is growing concern regarding catheter ablation performed under fluoroscopy guidance, due to its harmful effects for both patients and practitioners. The aim of this study was to assess the safety and effectiveness of zero-fluoroscopy cavotricuspid isthmus (CTI) ablation monitoring LI drop and CF as well as to elucidate if these parameters can predict successful radiofrequency (RF) applications in CTI ablation.
    Methods: We conducted a prospective observational study recruiting 50 consecutive patients who underwent CTI ablation. A zero-fluoroscopy approach guided by the combination of LI drop and CF was performed. In each RF application, CF and LI drop were monitored. A 6-month follow-up visit was scheduled to assess recurrences.
    Results: A total of 767 first-pass RF applications were evaluated in 50 patients. First-pass effective RF applications were associated with greater LI drops: absolute LI drops (30.05 ± 6.23 Ω vs. 25.01 ± 5.95 Ω),
    Conclusions: LI drop (absolute and relative values) appears to be a good predictor of successful RF applications to achieve CTI conduction block. The optimal CF to achieve a good LI drop is between 5 and 15 g. A zero-fluoroscopy approach guided by LI and CF was feasible, effective, and safe.
    Language English
    Publishing date 2024-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1322743
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  4. Article ; Online: Feasibility and safety of zero-fluoroscopy left bundle branch pacing: An initial experience.

    Ramos-Maqueda, Javier / Melero-Polo, Jorge / Montilla-Padilla, Isabel / Ruiz-Arroyo, José Ramón / Cabrera-Ramos, Mercedes

    Journal of cardiovascular electrophysiology

    2022  Volume 34, Issue 2, Page(s) 429–436

    Abstract: Introduction: Left bundle branch pacing (LBBP) has emerged in recent years as a new pacing modality, providing patients with a narrower paced QRS than conventional pacing and stable pacing parameters. At the same time, there is a growing concern about ... ...

    Abstract Introduction: Left bundle branch pacing (LBBP) has emerged in recent years as a new pacing modality, providing patients with a narrower paced QRS than conventional pacing and stable pacing parameters. At the same time, there is a growing concern about the use of fluoroscopy in pacemaker implantations, given its harmful effects on both patients and operators. However, there are no prior experiences of zero-fluoroscopy in LBBP procedure.
    Methods: We conducted an observational prospective study recruiting consecutive patients that underwent zero-fluoroscopy LBBP pacemaker implantation. A 6-month follow-up visit was programmed for every patient. The main goal of our study was to assess the efficacy, feasibility, and safety of the procedure.
    Results: From January 2021 to February 2022, we included 10 patients, 8 males. The average age was 63 ± 4 years. The procedure was successful in all patients. We observed a significant reduction in paced QRS width compared with basal QRS width (149 ± 31.9 vs. 116 ± 15.6 ms, p = .02). All device parameters remained stable at 6-month follow-up: no significant differences in mean impedance (700.5 ± 136.4 vs. 494 ± 72.7 Ohm, p = .09), capture threshold (0.67 ± 0.2 vs. 0.83 ± 0.2 V @ 0.4 ms, p = .27) or endocardial V-wave amplitude (10.6 ± 5.2 vs. 13.9 ± 6.3 mV, p = .19). No complications were reported in any case.
    Conclusion: Zero-fluoroscopy LBBP is feasible and safe, and it may be considered in cases where radiation exposure is contraindicated or especially undesirable. Future randomized clinical trials are needed for the widespread use of this new technique.
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Bundle of His ; Cardiac Pacing, Artificial/adverse effects ; Cardiac Pacing, Artificial/methods ; Prospective Studies ; Feasibility Studies ; Electrocardiography/methods ; Treatment Outcome
    Language English
    Publishing date 2022-12-15
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15765
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2863: Show issues Location:
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  5. Article ; Online: Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy.

    Ramos-Maqueda, Javier / Migueles, Jairo H / Molina-Jiménez, María / Ruiz-González, David / Cabrera-Borrego, Eva / Ruiz Salas, Amalio / Soriano-Maldonado, Alberto / Jimenez-Jaimez, Juan

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 13, Page(s) 992–999

    Abstract: Objective: To investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).: Methods: This multicentre, ... ...

    Abstract Objective: To investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).
    Methods: This multicentre, observational study enrolled 72 patients with AC, including right, left and biventricular forms of the disease, with underlying desmosomal and non-desmosomal mutations. Lifestyle physical activity, objectively monitored with accelerometers (ie, movement sensors) and RR-NSVT, identified as >188 bpm and >18 beats from a textile Holter ECG for 30 days.
    Results: Sixty-three patients with AC (38±17.6 years, 57% men) were included. A total of 17 patients experienced ≥1 RR-NSVTs, and a total of 35 events were recorded. The odds of occurrence of ≥1 RR-NSVT during the recording did not increase as a function of either total physical activity (OR 0.95, 95% CI (CI
    Conclusions: These findings suggest that lifestyle physical activity is not associated with RR-NSVTs in patients with AC.
    MeSH term(s) Male ; Humans ; Female ; Tachycardia, Ventricular/etiology ; Tachycardia, Ventricular/complications ; Electrocardiography, Ambulatory ; Cardiomyopathies/complications
    Language English
    Publishing date 2023-06-14
    Publishing country England
    Document type Multicenter Study ; Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2022-321824
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  6. Article ; Online: His-Bundle Pacing in a Patient With Tricuspid and Mitral Prosthetic Valves Without Suitable Coronary Veins for Lead Placement.

    Ramos-Maqueda, Javier / Cabrera-Ramos, Mercedes / Southard, Nicole / Riaño-Ondiviela, Adrián / Casasnovas-Lenguas, José Antonio / Ruiz-Arroyo, José Ramón

    CJC open

    2021  Volume 3, Issue 8, Page(s) 1082–1084

    Abstract: Atrioventricular block in patients with a prosthetic tricuspid valve and a pacemaker with a dysfunctional epicardial lead is not uncommon. In such instances, coronary sinus lead placement is the preferred option, but it has a failure rate of 10%-15%. An ... ...

    Abstract Atrioventricular block in patients with a prosthetic tricuspid valve and a pacemaker with a dysfunctional epicardial lead is not uncommon. In such instances, coronary sinus lead placement is the preferred option, but it has a failure rate of 10%-15%. An atrial transseptal left ventricular lead placement has been proposed as an alternative, but this approach is not feasible in patients with a prosthetic mitral valve. This analysis represents the first reported case of His-bundle pacing from the atria in a patient with prosthetic tricuspid and mitral valves, with no suitable coronary veins for lead placement.
    Language English
    Publishing date 2021-04-08
    Publishing country United States
    Document type Case Reports
    ISSN 2589-790X
    ISSN (online) 2589-790X
    DOI 10.1016/j.cjco.2021.03.012
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  7. Article ; Online: Improved procedural workflow for catheter ablation of paroxysmal AF with high-density mapping system and advanced technology: Rationale and study design of a multicenter international study.

    Solimene, Francesco / Stabile, Giuseppe / Ramos, Pablo / Segreti, Luca / Cauti, Filippo Maria / De Sanctis, Valerio / Maggio, Ruggero / Ramos-Maqueda, Javier / Mont, Lluis / Schillaci, Vincenzo / Malacrida, Maurizio / Garcia-Bolao, Ignacio

    Clinical cardiology

    2022  Volume 45, Issue 6, Page(s) 597–604

    Abstract: Background: The antral region of pulmonary veins (PV)s seems to play a key role in a strategy aimed at preventing atrial fibrillation (AF) recurrence. Particularly, low-voltage activity in tissue such as the PV antra and residual potential within the ... ...

    Abstract Background: The antral region of pulmonary veins (PV)s seems to play a key role in a strategy aimed at preventing atrial fibrillation (AF) recurrence. Particularly, low-voltage activity in tissue such as the PV antra and residual potential within the antral scar likely represent vulnerabilities in antral lesion sets, and ablation of these targets seems to improve freedom from AF. The aim of this study is to validate a structured application of an approach that includes the complete abolition of any antral potential achieving electrical quiescence in antral regions.
    Methods: The improveD procEdural workfLow for cathETEr ablation of paroxysmal AF with high density mapping system and advanced technology (DELETE AF) study is a prospective, single-arm, international post-market cohort study designed to demonstrate a low rate of clinical atrial arrhythmias recurrence with an improved procedural workflow for catheter ablation of paroxysmal AF, using the most advanced point-by-point RF ablation technology in a multicenter setting. About 300 consecutive patients with standard indications for AF ablation will be enrolled in this study. Post-ablation, all patients will be monitored with ambulatory event monitoring, starting within 30 days post-ablation to proactively detect and manage any recurrences within the 90-day blanking period, as well as Holter monitoring at 3, 6, 9, and 12 months post-ablation. Healthcare resource utilization, clinical data, complications, patients' medical complaints related to the ablation procedure and patient's reported outcome measures will be prospectively traced and evaluated.
    Discussion: The DELETE AF trial will provide additional knowledge on long-term outcome following a structured ablation workflow, with high density mapping, advanced algorithms and local impedance technology, in an international multicentric fashion. DELETE AF is registered at ClinicalTrials.gov (NCT05005143).
    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Cohort Studies ; Humans ; Prospective Studies ; Pulmonary Veins/surgery ; Recurrence ; Treatment Outcome ; Workflow
    Language English
    Publishing date 2022-04-21
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.23806
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    Zs.A 1423: Show issues Location:
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  8. Article ; Online: Magnetic resonance imaging in patients with cardiac implantable electronic devices: A prospective study.

    Navarro-Valverde, Cristina / Ramos-Maqueda, Javier / Romero-Reyes, M José / Esteve-Ruiz, Irene / García-Medina, Dolores / Pavón-Jiménez, Ricardo / Rodríguez-Gómez, Cristóbal / Leal-Del-Ojo, Juan / Cayuela, Aurelio / Molano-Casimiro, Francisco J

    Magnetic resonance imaging

    2022  Volume 91, Page(s) 9–15

    Abstract: Background: The number of patients with cardiac implantable electronic devices in whom magnetic resonance imaging (MRI) is indicated is constantly increasing. The potential risk of electromagnetic interference has limited its use and it is still ... ...

    Abstract Background: The number of patients with cardiac implantable electronic devices in whom magnetic resonance imaging (MRI) is indicated is constantly increasing. The potential risk of electromagnetic interference has limited its use and it is still contraindicated by the Food and Drug Administration in some cases. The aim of this study is to evaluate the safety and efficacy of MRI in these patients.
    Methods: A prospective registry comprising patients with a pacemaker (PM) or implantable cardioverter-defibrillator (ICD), MRI-conditional or not, who were candidates for MRI (at 1.5 T) with no suitable alternative diagnostic technique. All devices were programmed before the procedure and patients were monitored throughout the test. Clinical, electrical, and technical parameters were evaluated before and after MRI.
    Results: 147 MRI examinations (132 PM and 15 ICD) were performed. There were no clinical events or significant differences in the electrical parameters of the leads after MRI. A variation in the impedance of the ventricular leads was detected, although the difference was not clinically relevant. In one patient with a PM, a failure in release of the safety impulse was detected in the auto-threshold test, although the threshold was correctly determined. In 11 of the 17 thoracic MRIs, image artifacts were detected, preventing the diagnosis in two of them.
    Conclusions: In patients with cardiac implantable electronic devices, MRIs performed under a specific protocol has been shown to be safe in the short term even in the thoracic region, as well as interpretable in most cases.
    MeSH term(s) Defibrillators, Implantable/adverse effects ; Electronics ; Humans ; Magnetic Resonance Imaging/adverse effects ; Magnetic Resonance Imaging/methods ; Pacemaker, Artificial ; Prospective Studies
    Language English
    Publishing date 2022-05-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 604885-7
    ISSN 1873-5894 ; 0730-725X
    ISSN (online) 1873-5894
    ISSN 0730-725X
    DOI 10.1016/j.mri.2022.05.004
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    Zs.A 1817: Show issues Location:
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  9. Article ; Online: Predictores de fibrilación auricular en pacientes con ictus embólico de origen indeterminado.

    Ramos-Maqueda, Javier / Navarro-Valverde, Cristina / Esteve-Ruiz, Irene / Cabrera-Ramos, Mercedes / Rivera-López, Ricardo / García-Medina, Dolores / Pavón-Jiménez, Ricardo / Molano-Casimiro, Francisco Javier

    Medicina clinica

    2021  Volume 157, Issue 12, Page(s) 555–560

    Abstract: Background and objectives: Atrial fibrillation (AF) detection in patients with embolic stroke of underdetermined source (ESUS) entails a change of medical treatment and a significant decrease in the incidence of new strokes. It is necessary to determine ...

    Title translation Atrial fibrillation predictors in patients with embolic stroke of undetermined source.
    Abstract Background and objectives: Atrial fibrillation (AF) detection in patients with embolic stroke of underdetermined source (ESUS) entails a change of medical treatment and a significant decrease in the incidence of new strokes. It is necessary to determine which patients would benefit more from prolonged electrocardiographic monitoring. Our aim was to find electrocardiographic and echocardiographic AF predictors in patients with ESUS.
    Methods: We performed a cohort study that included 95 consecutive patients admitted to the hospital because of an ESUS. An electrocardiogram, each subject in the study underwent a 24-hour Holter-electrocardiogram (Holter-ECG) and an echocardiogram. A 2-year follow up was also conducted, with a 24-hour Holter-ECG every 3months for the first year, and every 6months during the second one.
    Results: During the follow-up, AF was detected in 11 patients (11.6%), with a detection rate of 3.2% at 6months, 7.4% at 12months, and 11.6% at 18months as well as at 24months. The variables that were independently related to AF detection included moderate or severe left atrium dilation (P=.02), interatrial advanced block (P=.04) and more than 1000 premature atrial beats on 24-hour Holter-ECG (P=.01).
    Conclusions: Moderate or severe atrial dilation, interatrial advanced block, and the presence of more than 1000 premature atrial beats on 24-hour Holter-ECG behave as AF predictors in patients with ESUS.
    MeSH term(s) Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Cohort Studies ; Embolic Stroke ; Humans ; Intracranial Embolism/diagnosis ; Intracranial Embolism/epidemiology ; Intracranial Embolism/etiology ; Risk Factors ; Stroke/epidemiology ; Stroke/etiology
    Language Spanish
    Publishing date 2021-01-29
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.09.024
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  10. Article ; Online: Results of catheter ablation with zero or near zero fluoroscopy in pediatric patients with supraventricular tachyarrhythmias.

    Ramos-Maqueda, Javier / Álvarez, Miguel / Cabrera-Ramos, Mercedes / Perin, Francesca / Rodríguez-Vázquez Del Rey, María Del Mar / Jiménez-Jaimez, Juan / Macías-Ruiz, Rosa / Molina-Lerma, Manuel / Sánchez-Millán, Pablo / Tercedor-Sánchez, Luis

    Revista espanola de cardiologia (English ed.)

    2021  Volume 75, Issue 2, Page(s) 166–173

    Abstract: Introduction and objectives: Ionizing radiation exposure in catheter ablation procedures carries health risks, especially in pediatric patients. Our aim was to compare the safety and efficacy of catheter ablation guided by a nonfluoroscopic intracardiac ...

    Abstract Introduction and objectives: Ionizing radiation exposure in catheter ablation procedures carries health risks, especially in pediatric patients. Our aim was to compare the safety and efficacy of catheter ablation guided by a nonfluoroscopic intracardiac navigation system (NFINS) with those of an exclusively fluoroscopy-guided approach in pediatric patients.
    Methods: We analyzed catheter ablation results in pediatric patients with high-risk accessory pathways or supraventricular tachycardia referred to our center during a 6-year period. We compared fluoroscopy-guided procedures (group A) with NFINS guided procedures (group B).
    Results: We analyzed 120 catheter ablation procedures in 110 pediatric patients (11±3.2 years, 70% male); there were 62 procedures in group A and 58 in group B. We found no significant differences between the 2 groups in procedure success (95% group A vs 93.5% group B; P=.53), complications (1.7% vs 1.6%; P=.23), or recurrences (7.3% vs 6.9%; P = .61). However, fluoroscopy time (median 1.1minutes vs 12minutes; P <.0005) and ablation time (median 96.5seconds vs 133.5seconds; P=.03) were lower in group B. The presence of structural heart disease was independently associated with recurrence (P=.03).
    Conclusions: The use of NFINS to guide catheter ablation procedures in pediatric patients reduces radiation exposure time. Its widespread use in pediatric ablations could decrease the risk of ionizing radiation.
    MeSH term(s) Accessory Atrioventricular Bundle ; Catheter Ablation ; Child ; Female ; Fluoroscopy ; Humans ; Male ; Tachycardia, Supraventricular/surgery ; Treatment Outcome
    Language Spanish
    Publishing date 2021-03-16
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2020.11.024
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