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  1. Article ; Online: A third-line antiretroviral therapy register to track patient clinical and virological outcomes.

    Naidoo, K / Ramruthan, J / Reddy, M / Lancaster, R

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

    2022  Volume 112, Issue 8, Page(s) 511–512

    MeSH term(s) Anti-HIV Agents/therapeutic use ; Anti-Retroviral Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; HIV Infections/drug therapy ; Humans ; South Africa ; Treatment Outcome ; Viral Load
    Chemical Substances Anti-HIV Agents ; Anti-Retroviral Agents
    Language English
    Publishing date 2022-08-01
    Publishing country South Africa
    Document type Editorial
    ZDB-ID 390968-2
    ISSN 2078-5135 ; 0038-2469 ; 0256-9574
    ISSN (online) 2078-5135
    ISSN 0038-2469 ; 0256-9574
    DOI 10.7196/SAMJ.2022.v112i8.16695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A third-line antiretroviral therapy register to track patient clinical and virological outcomes.

    Naidoo, K / Ramruthan, J / Reddy, M / Lancaster, R

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

    2022  Volume 112, Issue 8, Page(s) 511

    Abstract: In 2021, South Africa (SA) had an estimated 7.8 million people living with HIV, of whom 5.6 million were receiving antiretroviral therapy (ART),[1] with 3.4 million on first-line ART, 145 000 on second-line ART (SLART) and >700 on third-line ART (TLART). ...

    Abstract In 2021, South Africa (SA) had an estimated 7.8 million people living with HIV, of whom 5.6 million were receiving antiretroviral therapy (ART),[1] with 3.4 million on first-line ART, 145 000 on second-line ART (SLART) and >700 on third-line ART (TLART).
    MeSH term(s) Anti-HIV Agents/therapeutic use ; Anti-Retroviral Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; HIV Infections/drug therapy ; Humans ; South Africa/epidemiology ; Viral Load
    Chemical Substances Anti-HIV Agents ; Anti-Retroviral Agents
    Language English
    Publishing date 2022-08-02
    Publishing country South Africa
    Document type Editorial
    ZDB-ID 390968-2
    ISSN 2078-5135 ; 0038-2469 ; 0256-9574
    ISSN (online) 2078-5135
    ISSN 0038-2469 ; 0256-9574
    DOI 10.7196.SAMJ.v112i8.16695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Incidence and prevalence of hypertension among HIV-TB co-infected participants accessing treatment: A five-year prospective cohort analysis.

    Dawood, Halima / Yende-Zuma, Nonhlanhla / Singh, Upasna / Moodley, Mikaila C / Ramruthan, Jenine / Naidoo, Kogieleum

    PloS one

    2024  Volume 19, Issue 1, Page(s) e0297224

    Abstract: Introduction: Hypertension is a leading risk factor for cardiovascular disease among people living with human immunodeficiency virus (PLWH). This study determined incidence and prevalence of hypertension among PLWH receiving antiretroviral therapy (ART). ...

    Abstract Introduction: Hypertension is a leading risk factor for cardiovascular disease among people living with human immunodeficiency virus (PLWH). This study determined incidence and prevalence of hypertension among PLWH receiving antiretroviral therapy (ART).
    Method: We prospectively followed-up 642 HIV and tuberculosis (TB) co-infected study participants from 2005-2013. We defined hypertension as two consecutive elevated systolic and/or diastolic blood pressure measurements above 139/89 mmHg or current use of antihypertensive therapy.
    Results: Of 507 participants analyzed, 53% were women. Median [interquartile range (IQR)] age, body mass index (BMI), and CD4 count was 34 (28.0-40.0) years, 22.7 (20.5-25.4) kg/m2, and 145 (69.0-252.0) cells/mm3, respectively. Incidence [95% confidence interval (CI)] of both systolic and diastolic hypertension overall, in men, and in women over 40 years was 1.9 (1.4-2.6), 5.9 (3.6-9.6), and 5.0 (2.7-9.3) per 100 person-years (PY), respectively. Risk of developing hypertension was higher in men [(adjusted hazard ratio (aHR) 12.04, 95% CI: 4.35-33.32)] and women over 40 years (aHR 8.19, 95% CI 2.96-22.64), and in men below 40 years (aHR 2.79, 95% CI 0.95-8.23).
    Conclusion: Higher incidence rates of hypertension among older men and women accessing ART highlight opportunities to expand current integrated HIV-TB care models, to include cardiovascular disease risk screening and care to prevent premature death.
    MeSH term(s) Male ; Humans ; Female ; Aged ; HIV ; Incidence ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Prospective Studies ; Cardiovascular Diseases ; Prevalence ; Coinfection/epidemiology ; Cohort Studies ; Tuberculosis/complications ; Tuberculosis/drug therapy ; Tuberculosis/epidemiology ; Risk Factors ; Hypertension/complications ; Hypertension/epidemiology ; Hypertension/diagnosis
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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