LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 76

Search options

  1. Article ; Online: Clinical and laboratory characteristics of recovered versus deceased COVID-19 patients in Islamabad, Pakistan

    Rana, Muhammad Suleman

    Journal of Infection ; ISSN 0163-4453

    2020  

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.jinf.2020.11.013
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article ; Online: A hidden dilemma; post COVID-19 first detection of Varicella zoster M4 genotype from Pakistan.

    Hanif, Saba / Johnson, Sarah / Siddique, Maryam / Salman, Muhammad / Rana, Muhammad Suleman / Sharif, Shawana / Faryal, Rani

    Acta tropica

    2024  Volume 253, Page(s) 107162

    Abstract: Objectives: During the COVID-19 pandemic, the risk of childhood infectious diseases was increased. Post-COVID-19 escalation of chickenpox cases, becoming an emerging public health concern. Thus, the study was designed to compare chickenpox prevalence ... ...

    Abstract Objectives: During the COVID-19 pandemic, the risk of childhood infectious diseases was increased. Post-COVID-19 escalation of chickenpox cases, becoming an emerging public health concern. Thus, the study was designed to compare chickenpox prevalence and Varicella zoster virus (VZV) genotypes circulating before, during, and post-COVID-19 in Pakistan.
    Methods: A total of 267 lesion specimens collected from tertiary care hospitals, and chickenpox outbreaks from Pakistan were analysed by a two-amplicon approach with phylogenetic analysis.
    Results: Among suspected cases, overall 178/267 were VZV positive. Majority (84.2 %; 150/178) cases were of post-COVID-19 pandemic time. Small outbreaks occurred soon after COVID-19 in Rawalpindi and Islamabad (Pakistan), 40 positive cases out of 178 cases were outbreak cases. There was first time detection of the M4 genotype, which was significantly associated with disease severity (p = 0.0006) and post-COVID-19 chickenpox outbreaks in 2021 (77.9 %; 46/59; p < 0.00001). However, in pre-COVID-19 only M2 genotype was detected. The M2 prevalence varied from 2019 (100 %; 19/19) to 2022 (3.2 %; 3/91). However, the most prevalent strain of 2022 belonged to the M1 genotype (64.8 %; 59/91).
    Conclusion: A significant rise in chickenpox cases detected soon after COVID-19 in Pakistan, and oscillation of different VZV genotypes with first time detection of M4 genotype is an alarming situation. This demands further detailed genotypic studies on transmission dynamics of a rare M4 with other genotypes to protect the local population and restrict spread in other regions.
    MeSH term(s) Humans ; Chickenpox/epidemiology ; Chickenpox/diagnosis ; Pakistan/epidemiology ; Phylogeny ; Pandemics ; COVID-19/diagnosis ; COVID-19/epidemiology ; Herpesvirus 3, Human/genetics ; Genotype ; Herpes Zoster/diagnosis ; Herpes Zoster/epidemiology
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 210415-5
    ISSN 1873-6254 ; 0001-706X
    ISSN (online) 1873-6254
    ISSN 0001-706X
    DOI 10.1016/j.actatropica.2024.107162
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: The negative impact of the COVID-19 Pandemic on immunization and the positive impact on Polio eradication in Pakistan and Afghanistan.

    Rana, Muhammad Suleman / Usman, Mr Muhammad / Ikram, Aamer / Salman, Muhammad / Zaidi, Syed Sohail Zahoor / Umair, Massab

    The Journal of infection

    2022  Volume 85, Issue 2, Page(s) 174–211

    MeSH term(s) Afghanistan/epidemiology ; COVID-19/prevention & control ; Humans ; Immunization ; Immunization Programs ; Pakistan/epidemiology ; Pandemics/prevention & control ; Poliomyelitis/epidemiology ; Poliomyelitis/prevention & control ; Population Surveillance
    Language English
    Publishing date 2022-04-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.04.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The world's largest measles-Rubella vaccination campaign in Pakistan: Time to invest in routine immunization.

    Rana, Muhammad Suleman / Usman, Muhammad / Alam, Muhammad Masroor / Ikram, Aamer / Salman, Muhammad / Umair, Massab

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 5, Page(s) 2080444

    MeSH term(s) Humans ; Infant ; Pakistan ; Rubella/prevention & control ; Measles/prevention & control ; Immunization Programs ; Vaccination ; Measles Vaccine ; Rubella Vaccine
    Chemical Substances Measles Vaccine ; Rubella Vaccine
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2080444
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Impact of previous SARS-CoV-2 infection on the rate of mortality in dengue. A preliminary report from Pakistan.

    Rana, Muhammad Suleman / Usman, Muhammad / Alam, Muhammad Masroor / Ikram, Aamer / Salman, Muhammad / Umair, Massab

    The Journal of infection

    2022  Volume 84, Issue 5, Page(s) 722–746

    MeSH term(s) COVID-19 ; Dengue/epidemiology ; Dengue Virus ; Humans ; Pakistan/epidemiology ; SARS-CoV-2
    Language English
    Publishing date 2022-01-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.01.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: First report of coinfection and whole-genome sequencing of norovirus and sapovirus in an acute gastroenteritis patient from Pakistan.

    Umair, Massab / Rehman, Zaira / Haider, Syed Adnan / Usman, Muhammad / Rana, Muhammad Suleman / Ikram, Aamer / Salman, Muhammad

    Journal of medical virology

    2023  Volume 95, Issue 2, Page(s) e28458

    Abstract: Acute gastroenteritis is one of the most common diseases in infants and children in developing countries including Pakistan. In Pakistan, rotavirus (RVA) is known to contribute significantly to pediatric diarrheal illness, but the contribution of other ... ...

    Abstract Acute gastroenteritis is one of the most common diseases in infants and children in developing countries including Pakistan. In Pakistan, rotavirus (RVA) is known to contribute significantly to pediatric diarrheal illness, but the contribution of other viruses is still unclear. In the current study we have identified a case of mixed infection of norovirus (NoV) and sapovirus (SaV) in a 2-year-old child with acute gastroenteritis. The sample was initially processed for the detection of group A RVA through ELISA followed by NoV using RT-PCR assay. The sample tested positive for NoV RNA and was later subjected to whole-genome sequencing using meta-genome approach on Miseq (Illumina) platform. Sequencing results revealed GII.15 genotype of NoV that clustered with viruses from China and USA from 2017 to 2021. We also retrieved the complete genome of SaV (GI.1 genotype) from the same sample and phylogenetic analysis showed clustering with strains reported from Japan, South Korea, US, and Taiwan during 2012-2016. This is the first report from Pakistan that confirms coinfection of NoV and SaV and elucidates their whole genomes. We recommend initiation of NoV and SaV surveillance program to ascertain disease burden and explore genetic diversity, especially as RVA vaccines have been included in national immunization program.
    MeSH term(s) Infant ; Child ; Humans ; Child, Preschool ; Sapovirus/genetics ; Norovirus/genetics ; Coinfection ; Phylogeny ; Pakistan ; Caliciviridae Infections/epidemiology ; Gastroenteritis ; Viruses ; Genotype ; Feces
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28458
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Insights into measles virus: Serological surveillance and molecular characterization.

    Khalid, Zainab / Muhammad, Javed / Ali, Hina / Rana, Muhammad Suleman / Usman, Muhammad / Alam, Muhammad Masroor / Ullah, Riaz / Ullah, Arif / Umair, Massab / Ahmad, Ashfaq / Salman, Muhammad / Ikram, Aamer / Khan, Amjad / Bari, Ahmed

    Journal of infection and public health

    2024  Volume 17, Issue 6, Page(s) 994–1000

    Abstract: Background: Measles has been a significant public health concern in Pakistan, especially in the Khyber Pakhtunkhwa (KPK) province, where sporadic and silent epidemics continue to challenge existing control measures. This study aimed to estimate the ... ...

    Abstract Background: Measles has been a significant public health concern in Pakistan, especially in the Khyber Pakhtunkhwa (KPK) province, where sporadic and silent epidemics continue to challenge existing control measures. This study aimed to estimate the prevalence and investigate the molecular epidemiology of the measles virus (MeV) in KPK and explore the vaccination status among the suspected individuals.
    Methods: A cross-sectional study was conducted between February and October 2021. A total of 336 suspected measles cases from the study population were analyzed for IgM antibodies using Enzyme-Linked Immunosorbent Assay (ELISA). Throat swabs were randomly collected from a subset of positive cases for molecular analysis. Phylogenetic analysis of MeV isolates was performed using the neighbor-joining method. The vaccination status of individuals was also recorded.
    Results: Among the suspected participants, 61.0% (205/336) were ELISA positive for IgM antibodies, with a higher prevalence in males (64.17%) compared to females (57.04%). The majority of cases (36.0%) were observed in infants and toddlers, consistent with previous reports. The majority of IgM-positive cases (71.7%) had not received any dose of measles vaccine, highlighting gaps in vaccine coverage and the need for improved immunization programs. Genetic analysis revealed that all MeV isolates belonged to the B3 genotype, with minor genetic variations from previously reported variants in the region.
    Conclusion: This study provides valuable insights into the genetic epidemiology of the MeV in KPK, Pakistan. The high incidence of measles infection among unvaccinated individuals highlights the urgency of raising awareness about vaccine importance and strengthening routine immunization programs.
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2024.03.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Novel coronavirus outbreak in Pakistan: Beware of dengue.

    Rana, Muhammad Suleman / Ikram, Aamer / Alam, Muhammad Masroor / Salman, Muhammad

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2020  Volume 120, Issue 1 Pt 3, Page(s) 765–766

    MeSH term(s) COVID-19/epidemiology ; Dengue/epidemiology ; Disease Outbreaks ; Humans ; Pakistan/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-07-22
    Publishing country Singapore
    Document type Letter
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2020.07.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Overlapping clinical manifestations of COVID-19 with endemic infectious diseases in Pakistan: A looming threat of multiple lethal combinations.

    Rana, Muhammad Suleman / Usman, Muhammad / Alam, Muhammad Masroor / Ikram, Aamer / Salman, Muhammad

    Infection ecology & epidemiology

    2021  Volume 11, Issue 1, Page(s) 1873494

    Language English
    Publishing date 2021-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2627673-2
    ISSN 2000-8686
    ISSN 2000-8686
    DOI 10.1080/20008686.2021.1873494
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top