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  1. Book ; Online: The Art of DNA Strings

    Limbachiya, Dixita / Rao, Bansari / Gupta, Manish K.

    Sixteen Years of DNA Coding Theory

    2016  

    Abstract: The idea of computing with DNA was given by Tom Head in 1987, however in 1994 in a seminal paper, the actual successful experiment for DNA computing was performed by Adleman. The heart of the DNA computing is the DNA hybridization, however, it is also ... ...

    Abstract The idea of computing with DNA was given by Tom Head in 1987, however in 1994 in a seminal paper, the actual successful experiment for DNA computing was performed by Adleman. The heart of the DNA computing is the DNA hybridization, however, it is also the source of errors. Thus the success of the DNA computing depends on the error control techniques. The classical coding theory techniques have provided foundation for the current information and communication technology (ICT). Thus it is natural to expect that coding theory will be the foundational subject for the DNA computing paradigm. For the successful experiments with DNA computing usually we design DNA strings which are sufficiently dissimilar. This leads to the construction of a large set of DNA strings which satisfy certain combinatorial and thermodynamic constraints. Over the last 16 years, many approaches such as combinatorial, algebraic, computational have been used to construct such DNA strings. In this work, we survey this interesting area of DNA coding theory by providing key ideas of the area and current known results.

    Comment: 19 pages, 4 figures, draft review on DNA codes
    Keywords Computer Science - Information Theory ; Computer Science - Emerging Technologies
    Subject code 612
    Publishing date 2016-07-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12 to 18 months living in urban slums

    Mehta, Saurabh / Huey, Samantha L. / Ghugre, Padmini S. / Potdar, Ramesh D. / Venkatramanan, Sudha / Krisher, Jesse T. / Ruth, Caleb J. / Chopra, Harsha V. / Thorat, Aparna / Thakker, Varsha / Johnson, Lynn / Powis, Laura / Raveendran, Yadurshini / Haas, Jere D. / Finkelstein, Julia L. / Udipi, Shobha A. / Rajagopalan, Kripa / Research assistants / Iyer, Shobaha R. /
    Sonawane, Janhavi / Thorat, Tejashree / Bagal, Pratiksha / Pangerkar, Pranali / Kathar, Swati J. / Kadam, Priyanka / Saw, Rinki / Saw, Chinki / Saw, Lalita / Surve, Samrutthi / Majethiya, Sona / Mishra, Sonu / Rao, Bansari / Pawar, Anupriya / Shinde, Namrata / Fernandes, Monthie / Salvi, Ashwini / Cognitive function testing administrators / Devare, Komal Vilas / Sakat, Nalini / Vapilkar-Salpe, Chhaya / CSSC staff / Chavan, Sunanda / Community health workers and project clerks / Ambre, Varsha / Arde, Ragini Milind / Babrekar, Bhagyashri C. / Bhale, Anuja Sachin / Bhosale, Sakshi Samir / Devlekar, Ankita Arun / Dhanawade, Yojina / Dhotre, Vaibhavi / Faroqie, Afroz / Fernandes, Regina / Fernandes, Steffie / Ganekar, Suvarna Chandan / Ghadi, Sangeetha / Ghag, Mayuri / Hardas, Shubhada / Hiddujikar, Shanta Pundalik / Jadhav, Neelam Narayan / Jaiswal, Shivani / Jalankar, Neelam / Kadam, Suneetha / Kanade, Janvi Avadhut / Karande, Surekha Anil / Khade, Mangal / Kumbhar, Bharti Bhimrao / Lokhande, Jyothi Raghunath / Maingade, Dipika Dipak / Martal, Lakshmi / Mathkar, Prachi Pratap / Matondkar, Satyabhama Nhanu / Mestry, Kiran Ravindra / Mohite, Tripti / Naik, Akansha A. / Narkar, Namrata / Parab, Suvarna Santosh / Pendurkar, Ankita Ashok / Qamrunisa Shah, Seetamaya Saw / Shaikh, Bashirunnisa / Shaikh, Tasleem Rafique / Shaikh, Yasmin / Sheikh, Nazma / Surve, Sheetal S. / Tamble, Aditi / Tandel, Deepa / Tivrekar, Shraddha / Warang, Aswhini / Warang, Aswini / Pendurkar, Ashwini / Study physicians / Sahariah, Sirazul Ameen / Ojha, Sanjay / Feeding center managers / Auto-rickshaw drivers / Fernandes, Anthony / Kalogi, Vittal D.

    Clinical nutrition. 2022 Apr., v. 41, no. 4

    2022  

    Abstract: Biofortification of staple crops with higher levels of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target micronutrient deficiencies in low resource ... ...

    Institution Project Sabal
    Abstract Biofortification of staple crops with higher levels of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target micronutrient deficiencies in low resource settings, particularly among vulnerable populations such as children. We aimed to determine if iron- and zinc-biofortified pearl millet (FeZnPM, Dhanashakti, ICTP-8203Fe)-based complementary feeding improves nutritional status, including iron biomarkers and growth, in children living in urban slums of Mumbai. We conducted a randomized controlled trial of FeZnPM among 223 children aged 12–18 months who were not severely anemic at baseline (hemoglobin ≥9.0 g/dL). Children were randomized to receive either FeZnPM or conventional non-biofortified pearl millet (CPM) daily for 9 months. Iron status (hemoglobin, serum ferritin), plasma zinc, and anthropometric indicators (length, weight, mid-upper arm circumference, triceps and subscapular skinfolds) were evaluated at enrollment and throughout the trial. World Health Organization (WHO) anthropometric z-scores were calculated using WHO growth standards. Primary outcomes were hemoglobin and serum ferritin concentrations, and growth, defined as WHO z-scores. An intent to treat approach was used for analyses. We used the Hodges–Lehmann–Sen test to assess the change in primary outcomes between baseline and the last visit and report corresponding 95% confidence intervals. At baseline, 67.7% of children were anemic (hemoglobin <11.0 g/dL) and 59.6% were iron deficient (serum ferritin <12.0 μg/L). FeZnPM did not significantly increase iron biomarkers or improve growth, compared to CPM. In subgroup analyses, FeZnPM improved hemoglobin concentrations in male children, and in children with iron deficiency or iron depletion (serum ferritin <25.0 μg/L) at baseline, relative to CPM. Daily consumption of FeZnPM-based complementary foods did not significantly impact iron and zinc status or growth in children living in Mumbai's urban slums. However, the intervention significantly improved hemoglobin concentrations among male children and among individuals who were iron-deficient or iron-depleted at baseline. This trial is registered with Clinicaltrials.gov (ID: NCT02233764), and Clinical Trials Registry of India (ID: REF/2014/10/007731).
    Keywords Cenchrus americanus ; World Health Organization ; anemia ; arm circumference ; biofortification ; biomarkers ; blood serum ; clinical nutrition ; complementary feeding ; ferritin ; hemoglobin ; males ; nutritional status ; randomized clinical trials ; zinc ; India
    Language English
    Dates of publication 2022-04
    Size p. 937-947.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2022.02.014
    Database NAL-Catalogue (AGRICOLA)

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