Article ; Online: A comparative clinical and histopathological pilot study of different fractional CO
Journal of cosmetic dermatology
2020 Volume 20, Issue 1, Page(s) 116–123
Abstract: Background: Atrophic scars cause significant patient morbidity. Fractional photothermolysis is one of the most effective treatment options used to resurface scars of different etiologies.: Aims: To assess the efficacy and safety of different ... ...
Abstract | Background: Atrophic scars cause significant patient morbidity. Fractional photothermolysis is one of the most effective treatment options used to resurface scars of different etiologies. Aims: To assess the efficacy and safety of different fractional ablative CO Methods: A prospective pilot study of 20 adult male patients (skin types Π- Ⅳ, aged 18-45) with post-traumatic atrophic linear scars were divided into 2 groups each comprising 10 patients receiving different fractional CO Results: The study showed statistically significant reduction in average scar volume in both groups (P < .01), with reduction in depth more obvious than reduction in width or length in both groups. There was a highly significant difference in overall scar improvement represented by scar volume between both groups (P < .01) with an average reduction in scar volume of 42.85% in group (a) compared with 35.29% in group (b). Also, there was a highly statistically significant increase in both epidermal and papillary and reticular dermis thickness in both groups after treatment. However, the difference between both groups was nonsignificant. Side effects were mild, well tolerated, and transient. Conclusion: Fractional CO |
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MeSH term(s) | Adolescent ; Adult ; Carbon Dioxide ; Cicatrix/etiology ; Cicatrix/pathology ; Humans ; Lasers, Gas/adverse effects ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Treatment Outcome ; Young Adult |
Chemical Substances | Carbon Dioxide (142M471B3J) |
Language | English |
Publishing date | 2020-05-30 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 2280551-5 |
ISSN | 1473-2165 ; 1473-2130 |
ISSN (online) | 1473-2165 |
ISSN | 1473-2130 |
DOI | 10.1111/jocd.13489 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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