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  1. AU="Raux, M"
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  1. Article ; Online: From descriptive epidemiology to interventional epidemiology: The central role of epidemiologists in COVID-19 crisis management.

    Gayat, Etienne / Raux, Mathieu

    Anaesthesia, critical care & pain medicine

    2022  Volume 41, Issue 2, Page(s) 101056

    MeSH term(s) COVID-19 ; Epidemiologists ; Humans ; Public Health ; Research ; Workforce
    Language English
    Publishing date 2022-05-06
    Publishing country France
    Document type Editorial
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2022.101056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Heterogeneity in defining multiple trauma: a systematic review of randomized controlled trials.

    Jeanmougin, Thomas / Cole, Elaine / Duceau, Baptiste / Raux, Mathieu / James, Arthur

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 363

    Abstract: Introduction: While numerous randomized controlled trials (RCTs) have been conducted in the field of trauma, a substantial portion of them are yielding negative results. One potential contributing factor to this trend could be the lack of agreement ... ...

    Abstract Introduction: While numerous randomized controlled trials (RCTs) have been conducted in the field of trauma, a substantial portion of them are yielding negative results. One potential contributing factor to this trend could be the lack of agreement regarding the chosen definitions across different trials. The primary objective was to identify the terminology and definitions utilized for the characterization of multiple trauma patients within randomized controlled trials (RCTs).
    Methods: A systematic review of the literature was performed in MEDLINE, EMBASE and clinicaltrials.gov between January 1, 2002, and July 31, 2022. RCTs or RTCs protocols were eligible if they included multiple trauma patients. The terms employed to characterize patient populations were identified, and the corresponding definitions for these terms were extracted. The subsequent impact on the population recruited was then documented to expose clinical heterogeneity.
    Results: Fifty RCTs were included, and 12 different terms identified. Among these terms, the most frequently used were "multiple trauma" (n = 21, 42%), "severe trauma" (n = 8, 16%), "major trauma" (n = 4, 8%), and trauma with hemorrhagic shock" (n = 4, 8%). Only 62% of RCTs (n = 31) provided a definition for the terms used, resulting a total of 21 different definitions. These definitions primarily relied on the injury severity score (ISS) (n = 15, 30%), displaying an important underlying heterogeneity. The choice of the terms had an impact on the study population, affecting both the ISS and in-hospital mortality. Eleven protocols were included, featuring five different terms, with "severe trauma" being the most frequent, occurring six times (55%).
    Conclusion: This systematic review uncovers an important heterogeneity both in the terms and in the definitions employed to recruit trauma patients within RCTs. These findings underscore the imperative of promoting the use of a unique and consistent definition.
    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Multiple Trauma/therapy ; Hospital Mortality ; Injury Severity Score ; Shock, Hemorrhagic
    Language English
    Publishing date 2023-09-22
    Publishing country England
    Document type Systematic Review ; Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04637-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Algorithm of Femoropopliteal Endovascular Treatment.

    Dubosq, Maxime / Raux, Maxime / Nasr, Bahaa / Gouëffic, Yann

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 9

    Abstract: Background and Objectives: Indications for the endovascular treatment of femoropopliteal lesions have steadily increased over the past decade. Accordingly, the number of devices has also increased, but the choice of the best endovascular treatment ... ...

    Abstract Background and Objectives: Indications for the endovascular treatment of femoropopliteal lesions have steadily increased over the past decade. Accordingly, the number of devices has also increased, but the choice of the best endovascular treatment remains to be defined. Many devices are now available for physicians. However, in order to obtain a high success rate, it is necessary to respect an algorithm whose choice of device is only one step in the treatment. Materials and Methods: The first step is, therefore, to define the approach according to the lesion to be treated. Anterograde approaches (femoral, radial, or humeral) are distinguished from retrograde approaches depending on the patient’s anatomy and surgical history. Secondarily, the lesion will be crossed intraluminally or subintimally using a catheter or an angioplasty balloon. The third step corresponds to the preparation of the artery, which is essential before the implantation of the device. It has a crucial role in reducing the rate of restenosis. Several tools are available and are chosen according to the lesion requiring treatment (stenosis, occlusion). Among them, we find the angioplasty balloon, the atherectomy probes, or intravascular lithotripsy. Finally, the last step corresponds to the choice of the device to be implanted. This is also based on the nature of the lesion, which is considered short, up to 15 cm and complex beyond that. The choice of device will be between bare stents, covered stents, drug-coated balloons, and drug-eluting stents. Currently, drug-eluting stents appear to be the treatment of choice for short lesions, and active devices seem to be the preferred treatment for more complex lesions, although there is a lack of data. Results: In case of failure to cross the lesion, the retrograde approach is a safe and effective alternative. Balloon angioplasty currently remains the reference method for the preparation of the artery, the aim of which is to ensure the intraoperative technical success of the treatment (residual stenosis < 30%), to limit the risk of dissection and, finally, to limit the occurrence of restenosis. Concerning the treatment, the drug-eluting devices seem to present the best results, whether for simple or complex lesions. Conclusions: Endovascular treatment for femoropopliteal lesions needs to be considered upstream of the intervention in order to anticipate the treatment and the choice of devices for each stage.
    MeSH term(s) Algorithms ; Constriction, Pathologic ; Humans ; Peripheral Arterial Disease/surgery ; Popliteal Artery/surgery ; Stents ; Treatment Outcome ; Vascular Patency
    Language English
    Publishing date 2022-09-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58091293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Altmetrics scores: What are they?

    James, Arthur / Raux, Matthieu

    Anaesthesia, critical care & pain medicine

    2020  Volume 39, Issue 3, Page(s) 443–445

    MeSH term(s) Algorithms ; Anesthesiology ; Journal Impact Factor ; Periodicals as Topic
    Language English
    Publishing date 2020-03-14
    Publishing country France
    Document type Letter
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2020.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply to Vassallo et al., triage score needs a careful methodological evaluation.

    James, Arthur / Riou, Bruno / Raux, Mathieu

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2021  Volume 28, Issue 2, Page(s) 162–163

    MeSH term(s) Humans ; Mass Casualty Incidents ; Paris ; Terrorism ; Triage
    Language English
    Publishing date 2021-03-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Regarding "Systematic review and meta-analysis of endovascular versus open repair for common femoral artery atherosclerosis treatment".

    Gouëffic, Yann / Chatellier, Gilles / Raux, Maxime / Nasr, Bahaa

    Journal of vascular surgery

    2021  Volume 74, Issue 2, Page(s) 681

    MeSH term(s) Atherosclerosis/diagnostic imaging ; Atherosclerosis/therapy ; Endovascular Procedures/adverse effects ; Femoral Artery/diagnostic imaging ; Femoral Artery/surgery ; Humans
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2021.01.071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Embolisation des anévrysmes de l’artère splénique : traitement de choix. À propos d’un cas et revue de la littérature.

    Tijani, Y / Zahdi, O / Hormat-Allah, M / Zaid, Y / Raux, M / Gouëffic, Y

    Annales de cardiologie et d'angeiologie

    2020  Volume 71, Issue 2, Page(s) 108–111

    Abstract: Splenic artery aneurysms constitute 60% of digestive artery aneurysms. They are often discovered incidentally and by imaging. Currently, endovascular treatment is considered the first-line treatment, as it is less invasive with less morbidity and ... ...

    Title translation Embolization of splenic artery aneurysms: Treatment of choice. About a case and review of the literature.
    Abstract Splenic artery aneurysms constitute 60% of digestive artery aneurysms. They are often discovered incidentally and by imaging. Currently, endovascular treatment is considered the first-line treatment, as it is less invasive with less morbidity and mortality than surgery. An aggressive approach in their management is certainly justified because the overall mortality of ruptured splenic aneurysms is 25%. False splenic aneurysms have a greater potential for rupture than true aneurysms because they grow faster. Endovascular treatment is generally indicated for aneurysms larger than 2cm or with an increase in size of more than 0.5cm/year. Embolization is rarely associated with an infarction of the spleen due to the good supply of short gastric vessels. Embolization is performed using different materials including coils, which can be used alone or with other embolic agents. Post-embolization syndrome can be seen with persistent pain, fever and other systemic symptoms. Endovascular treatment compared to open surgery is associated with better quality of life and appears to be the most cost-effective strategy. Endovascular treatment and especially coil embolization are starting to be the standard treatment. Surgical and laparoscopic treatment are reserved for ruptured aneurysms which are burdened with significant mortality, especially in pregnant women. We report the case of a 66-year-old female patient in whom a splenic artery aneurysm was discovered incidentally during an ultrasound for an ovarian cyst.
    MeSH term(s) Aged ; Aneurysm, False ; Aneurysm, Ruptured/diagnostic imaging ; Aneurysm, Ruptured/therapy ; Embolization, Therapeutic/methods ; Female ; Humans ; Pregnancy ; Quality of Life ; Splenic Artery/diagnostic imaging ; Splenic Artery/surgery ; Treatment Outcome
    Language French
    Publishing date 2020-11-29
    Publishing country France
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 418425-7
    ISSN 1768-3181 ; 0003-3928
    ISSN (online) 1768-3181
    ISSN 0003-3928
    DOI 10.1016/j.ancard.2020.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Depacked patients who underwent a shortened perihepatic packing for severe blunt liver trauma have a high survival rate: 20 years of experience in a level I trauma center.

    Martellotto, Sophie / Melot, Charlotte / Raux, Mathieu / Chereau, Nathalie / Menegaux, Fabrice

    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland

    2021  Volume 20, Issue 3, Page(s) e20–e25

    Abstract: Introduction: Non-operative management is currently the preferred approach in blunt liver trauma, including high grade liver lesions. However, hemodynamic instability imposes the need for an emergency laparotomy, with a perihepatic packing (PHP) to ... ...

    Abstract Introduction: Non-operative management is currently the preferred approach in blunt liver trauma, including high grade liver lesions. However, hemodynamic instability imposes the need for an emergency laparotomy, with a perihepatic packing (PHP) to control liver bleeding in most cases. Our retrospective study aimed to assess the outcomes of liver trauma patients who underwent a shortened PHP.
    Methods: All consecutive patients who underwent PHP for blunt liver trauma from 1998 to 2019 in our Level I trauma center were included in the study. Unstable patients with severe liver trauma were transferred to the operating room without any delay, and a collective decision was made to perform abbreviated laparotomy to pack the liver. Demographics, perioperative data, postoperative outcomes, and mortality were retrospectively collected, and survivors and deceased patients were compared with a paired t-test.
    Results: Fifty-nine patients of 206 patients admitted with severe liver injuries were treated with shortened PHP. Thirty-four (57.6%) patients died, including 26 (76.5%) within the first 24 h. Twelve (20.3%) patients had a selective hepatic embolization and eight (13.6%) had an extrahepatic embolization. Forty-eight patients had an extra abdominal associated injury. This was not a predictive factor of mortality. The removal of packing was performed in 24 patients within 72 h after laparotomy, with an 80% survival rate in these patients.
    Conclusion: Shortened PHP is an effective strategy for controlling liver bleeding in severe hepatic trauma. The mortality rate of these patients is high, but after the removal of packing, the survival is good.
    MeSH term(s) Abdominal Injuries/complications ; Abdominal Injuries/surgery ; Hemorrhage/pathology ; Hemorrhage/therapy ; Humans ; Liver/injuries ; Liver/surgery ; Liver Diseases ; Retrospective Studies ; Survival Rate ; Trauma Centers ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/surgery
    Language English
    Publishing date 2021-06-18
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2102927-1
    ISSN 1479-666X
    ISSN 1479-666X
    DOI 10.1016/j.surge.2021.04.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Organizational innovation under constraints: The case of covid patients' flow management in Parisian hospitals.

    Gomez, Marie-Léandre / Kerveillant, Marie / Langlois, Matthieu / Lot, Nicolas / Raux, Mathieu

    Health services management research

    2022  Volume 36, Issue 2, Page(s) 137–144

    Abstract: The COVID crisis has put hospitals under great stress over the past 2 years and some institutions came close to their breaking points. This has often forced decision makers and the entire institutions to change their practices and the organization of the ...

    Abstract The COVID crisis has put hospitals under great stress over the past 2 years and some institutions came close to their breaking points. This has often forced decision makers and the entire institutions to change their practices and the organization of the hospitals in order to continue operating despite limited resources. It has also led some hospitals to develop and implement organizational innovations. This article is based on a qualitative case study analyzing the case of a crisis unit that has implemented various innovative medical and organizational actions in order to manage the flow of resuscitation Covid patients in a large group of hospitals in Paris. This team has implemented a new evaluation scale of resuscitation needs in order to better manage quantitatively and qualitatively the patients' flow; it has defined medical criteria to select the patients eligible for transfer; it has organized one hundred patients transfers to other hospitals' intensive care units, in and out of the region, involving private hospitals and private ambulances for a new collaboration. The case allows us to understand innovation in the midst of an extreme situation, when material and human resources are highly constrained, and with very strong time pressure. We highlight the importance of implementing flexible organizational processes and staffing the crisis team with physicians and nurses with specific and complementary skills and experience in flow management and crisis situations.
    MeSH term(s) Humans ; COVID-19 ; Hospitals ; Organizational Innovation
    Language English
    Publishing date 2022-07-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645114-7
    ISSN 1758-1044 ; 0951-4848
    ISSN (online) 1758-1044
    ISSN 0951-4848
    DOI 10.1177/09514848221115243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Completeness and Mismatch of Patient-Important Outcomes After Trauma.

    James, Arthur / Ravaud, Philippe / Riveros, Carolina / Raux, Mathieu / Tran, Viet-Thi

    Annals of surgery open : perspectives of surgical history, education, and clinical approaches

    2022  Volume 3, Issue 4, Page(s) e211

    Abstract: To assess the completeness of the collection of patient-important outcomes and the mismatch between outcomes measured in research and patients' important issues after trauma.: Summary background data: To date, severe trauma has mainly been assessed ... ...

    Abstract To assess the completeness of the collection of patient-important outcomes and the mismatch between outcomes measured in research and patients' important issues after trauma.
    Summary background data: To date, severe trauma has mainly been assessed using in-hospital mortality. Yet, with 80 to 90% survivors discharged from hospital, it is critical to assess the collection of patient important long-term outcomes of trauma.
    Methods: Mixed methods study combining a systematic review of outcomes and their comparison with domains elicited by patients during a qualitative study. We searched Medline, EMBASE and clinicaltrials.gov from January 1, 2014 to September 30, 2019 and extracted all outcomes from reports including severe trauma. We compared these outcomes with 97 domains that matter to trauma survivors identified in a previous qualitative study. We defined as patient-important outcome as the 10 most frequently elicited domains in the qualitative study. We assessed the number of domains captured in each report to illustrate the completeness of the collection of patient-important outcomes. We also assessed the mismatch between outcomes collected and what matters to patients.
    Findings: Among the 116 reports included in the systematic review, we identified 403 outcomes collected with 154 unique measurements tools. Beside mortality, measurement tools most frequently used were the Glasgow Outcome Scale (31.0%, n=36), questions on patients' return to work (20,7%, n=24) and the EQ-5D (19.0%, n=22). The comparison between the outcomes identified in the systematic review and the domains from the qualitative study found that 10.3% (n=12) reports did not collect any patient-important domains and one collected all 10 patient-important domains. By examining each of the 10 patient-important domains, none was collected in more than 72% of reports and only five were among the ten most frequently measured domains in studies.
    Conclusion: The completeness of the collection of the long-term patient-important outcomes after trauma can be improved. There was a mismatch between the domains used in the literature and those considered important by patients during a qualitative study.
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3593
    ISSN (online) 2691-3593
    DOI 10.1097/AS9.0000000000000211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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