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  1. AU="Rawlinson, Jennifer R"
  2. AU="Priti N Mody-Pan"
  3. AU="Yunusov, Marat S"
  4. AU=Peever John
  5. AU="Khosravi, Majid"
  6. AU="Xiang, La"
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  12. AU=Yu Xiongwu
  13. AU=Greenland Sander
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  16. AU="Soucek, Alexander"
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  1. Artikel: Hematologic, Biochemical, and Endocrine Parameters in Horses With Tooth Resorption and Hypercementosis

    Earley, Edward T / Baratt, Robert M / Cox, Victor. S / Dotzel, Allison. R / Galloway, Stephen S / Perkins, Gillian A / Rawlinson, Jennifer R / Refsal, Kent R / Scarlett, Janet M / Smedley, Rebecca C

    Journal of veterinary dentistry. , v. 34, no. 3

    2017  

    Abstract: Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a frequently diagnosed condition in adult horses. The underlying etiology is still unknown. Hematologic, biochemical, and endocrine values have not been reported in EOTRH-affected ... ...

    Abstract Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a frequently diagnosed condition in adult horses. The underlying etiology is still unknown. Hematologic, biochemical, and endocrine values have not been reported in EOTRH-affected horses. The main objective of the study was to describe the hematologic, biochemical, and endocrine parameters in horses with EOTRH. Descriptive cross-sectional study of client-owned animals with EOTRH. A complete blood count, biochemistry panel, and endocrine profile were performed in horses diagnosed with EOTRH. Diagnosis was based on oral and radiographic examination findings and confirmed with histopathology. Eighteen horses with EOTRH aged 10 to 32 years from various regions of the United States were sampled. The only consistent abnormality on the complete blood cell count and chemistry panel was hypoalbuminemia (88%). Endocrine parameters demonstrated no major abnormalities in the functioning of the thyroid and pituitary pars intermedia. The parathyroid hormone concentration was increased in 7 (47%) of 15 horses with an elevated 25-hydroxy vitamin D in 3 (17%) of 17 horses. The main limitations of this study are the small sample size and lack of age-matched and management-matched control horses. The relevance of elevated parathyroid hormone in this study cannot be determined due to the lack of age-based controls and large population studies. With the small population evaluated in this study, there are no obvious hematological, biochemical, and endocrine changes evident. Further evaluation with signalment-matched controls will be necessary to evaluate some trends noted in the laboratory values.
    Schlagwörter adults ; blood ; bone resorption ; cross-sectional studies ; etiology ; histopathology ; horses ; hypoalbuminemia ; parathyroid hormone ; radiography ; teeth ; tooth resorption ; veterinary dentistry ; vitamin D
    Sprache Englisch
    Erscheinungsverlauf 2017-09
    Umfang p. 155-160.
    Erscheinungsort SAGE Publications
    Dokumenttyp Artikel
    ISSN 2470-4083
    DOI 10.1177/0898756417717039
    Datenquelle NAL Katalog (AGRICOLA)

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  2. Artikel: Hematologic, Biochemical, and Endocrine Parameters in Horses With Tooth Resorption and Hypercementosis.

    Earley, Edward T / Rawlinson, Jennifer R / Baratt, Robert M / Galloway, Stephen S / Smedley, Rebecca C / Scarlett, Janet M / Refsal, Kent R / Dotzel, Allison R / Cox, Victor S / Perkins, Gillian A

    Journal of veterinary dentistry

    2017  Band 34, Heft 3, Seite(n) 155–160

    Abstract: Background: Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a frequently diagnosed condition in adult horses. The underlying etiology is still unknown. Hematologic, biochemical, and endocrine values have not been reported in EOTRH- ... ...

    Abstract Background: Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a frequently diagnosed condition in adult horses. The underlying etiology is still unknown. Hematologic, biochemical, and endocrine values have not been reported in EOTRH-affected horses.
    Objectives: The main objective of the study was to describe the hematologic, biochemical, and endocrine parameters in horses with EOTRH.
    Study design: Descriptive cross-sectional study of client-owned animals with EOTRH.
    Methods: A complete blood count, biochemistry panel, and endocrine profile were performed in horses diagnosed with EOTRH. Diagnosis was based on oral and radiographic examination findings and confirmed with histopathology.
    Results: Eighteen horses with EOTRH aged 10 to 32 years from various regions of the United States were sampled. The only consistent abnormality on the complete blood cell count and chemistry panel was hypoalbuminemia (88%). Endocrine parameters demonstrated no major abnormalities in the functioning of the thyroid and pituitary pars intermedia. The parathyroid hormone concentration was increased in 7 (47%) of 15 horses with an elevated 25-hydroxy vitamin D in 3 (17%) of 17 horses. Main Limitations: The main limitations of this study are the small sample size and lack of age-matched and management-matched control horses.
    Conclusions: The relevance of elevated parathyroid hormone in this study cannot be determined due to the lack of age-based controls and large population studies. With the small population evaluated in this study, there are no obvious hematological, biochemical, and endocrine changes evident. Further evaluation with signalment-matched controls will be necessary to evaluate some trends noted in the laboratory values.
    Mesh-Begriff(e) Animals ; Cross-Sectional Studies ; Female ; Horse Diseases/blood ; Horse Diseases/etiology ; Horse Diseases/physiopathology ; Horses ; Hypercementosis/blood ; Hypercementosis/etiology ; Hypercementosis/physiopathology ; Hypercementosis/veterinary ; Male ; Prospective Studies ; Tooth Resorption/blood ; Tooth Resorption/etiology ; Tooth Resorption/physiopathology ; Tooth Resorption/veterinary
    Sprache Englisch
    Erscheinungsdatum 2017-08-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 0898-7564
    ISSN 0898-7564
    DOI 10.1177/0898756417717039
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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