Article: Complication and response assessment of high-dose-rate endorectal brachytherapy boost in neo-adjuvant chemoradiotherapy of locally advanced rectal cancer with long-term outcomes.
Journal of contemporary brachytherapy
2023 Volume 15, Issue 2, Page(s) 117–122
Abstract: Purpose: To identify efficacy, complication, and pathologic response of high-dose-rate endorectal brachytherapy (HDR-BRT) boost in neo-adjuvant chemoradiotherapy (nCRT) of locally advanced rectal cancer.: Material and methods: Forty-four patients who ...
| Abstract | Purpose: To identify efficacy, complication, and pathologic response of high-dose-rate endorectal brachytherapy (HDR-BRT) boost in neo-adjuvant chemoradiotherapy (nCRT) of locally advanced rectal cancer. Material and methods: Forty-four patients who met eligibility criteria were included in this non-randomized comparative study. Control group was recruited retrospectively. nCRT (50.40 Gy/28 fr. plus capecitabine 825 mg/m Results: From 44 patients in the case and control groups, pCR was 11 (50%) and 8 (36.4%), respectively ( Conclusions: Treatment schedule was well-tolerated, and neo-adjuvant HDR-BRT could achieve better T down-staging as a boost comparing with nCRT, without significant complication. However, the optimal dose and fractions in the context of HDR-BRT boost needs further studies. |
|---|---|
| Language | English |
| Publishing date | 2023-04-28 |
| Publishing country | Poland |
| Document type | Journal Article |
| ZDB-ID | 2627721-9 |
| ISSN | 2081-2841 ; 1689-832X |
| ISSN (online) | 2081-2841 |
| ISSN | 1689-832X |
| DOI | 10.5114/jcb.2023.127051 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.