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Article ; Online: RDS-NExT workshop: consensus statements for the use of surfactant in preterm neonates with RDS.

Bhandari, Vineet / Black, Rachel / Gandhi, Bheru / Hogue, Susan / Kakkilaya, Venkatakrishna / Mikhael, Michel / Moya, Fernando / Pezzano, Chad / Read, Pam / Roberts, Kari D / Ryan, Rita M / Stanford, Richard H / Wright, Clyde J

Journal of perinatology : official journal of the California Perinatal Association

2023  Volume 43, Issue 8, Page(s) 982–990

Abstract: Objective: To provide the best clinical practice guidance for surfactant use in preterm neonates with respiratory distress syndrome (RDS). The RDS-Neonatal Expert Taskforce (RDS-NExT) initiative was intended to add to existing evidence and clinical ... ...

Abstract Objective: To provide the best clinical practice guidance for surfactant use in preterm neonates with respiratory distress syndrome (RDS). The RDS-Neonatal Expert Taskforce (RDS-NExT) initiative was intended to add to existing evidence and clinical guidelines, where evidence is lacking, with input from an expert panel.
Study design: An expert panel of healthcare providers specializing in neonatal intensive care was convened and administered a survey questionnaire, followed by 3 virtual workshops. A modified Delphi method was used to obtain consensus around topics in surfactant use in neonatal RDS.
Result: Statements focused on establishing RDS diagnosis and indicators for surfactant administration, surfactant administration methods and techniques, and other considerations. After discussion and voting, consensus was achieved on 20 statements.
Conclusion: These consensus statements provide practical guidance for surfactant administration in preterm neonates with RDS, with a goal to contribute to improving the care of neonates and providing a stimulus for further investigation to bridge existing knowledge gaps.
MeSH term(s) Infant, Newborn ; Humans ; Infant, Premature ; Surface-Active Agents/therapeutic use ; Respiratory Distress Syndrome, Newborn/drug therapy ; Pulmonary Surfactants/therapeutic use ; Intensive Care, Neonatal
Chemical Substances Surface-Active Agents ; Pulmonary Surfactants
Language English
Publishing date 2023-05-15
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 645021-0
ISSN 1476-5543 ; 0743-8346
ISSN (online) 1476-5543
ISSN 0743-8346
DOI 10.1038/s41372-023-01690-9
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