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Article ; Online: SARS-CoV-2 diagnostic diary

Marcio da Costa Cipitelli / Elizabeth Valentin / Nadia Vaez Gonçalves da Cruz / Tatiana LS Nogueira / Elaine Cristina Amaro de Melo / Rebeca Araujo da Silva / Marcelo M Serra / André L Meriano / Alberto ML Colares / Marcos Dornelas-Ribeiro / Caleb GM Santos

Memórias do Instituto Oswaldo Cruz., Vol

from rumors to the first case. Early reports of molecular tests from the military research and diagnostic institute of Rio de Janeiro

2020  Volume 115

Abstract: Corona virus disease (COVID-19) presents a serious threat to global health. A historical timeline of early molecular diagnostics from government alert (January 22) (D) was presented. After in silico analysis, Brazilian Army Institute of Biology (IBEx-RJ) ...

Abstract Corona virus disease (COVID-19) presents a serious threat to global health. A historical timeline of early molecular diagnostics from government alert (January 22) (D) was presented. After in silico analysis, Brazilian Army Institute of Biology (IBEx-RJ) tested samples in house using real-time reverse transcriptase polymerase chain reaction (RT-PCR) (fast mode) based on Centers for Disease Control and Prevention (CDC) recommendations. First cases from Brazil, Rio de Janeiro, IBEx, and diagnosis team were reported in D36, D44, D66, and D74 respectively. Therefore, after 1300 tests, we recommend N1/N2 primer sets (CDC) for preliminary and Charité protocol confirmation in case of positive results. Moreover, every professional should be tested before starting work, in addition to weekly tests for everyone involved.
Keywords coronavirus ; SARS-CoV-2 ; RT-PCR ; global pandemic ; COVID-19 ; Arctic medicine. Tropical medicine ; RC955-962 ; Microbiology ; QR1-502
Language English
Publishing date 2020-07-01T00:00:00Z
Publisher Instituto Oswaldo Cruz, Ministério da Saúde
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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