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  1. Article: Response to Letter to the Editor, "Mechanical Ventilation in COVID-19 Patients: a question from Age to Frailty".

    Ecarnot, Fiona / Rebora, Paola / Bellelli, Giuseppe

    Aging and disease

    2023  Volume 14, Issue 2, Page(s) 258–259

    Language English
    Publishing date 2023-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2625789-0
    ISSN 2152-5250
    ISSN 2152-5250
    DOI 10.14336/AD.2022.0819-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Letter to the editor on "New weighting methods when cases are only a subset of events in a nested case-control study" by Qian M. Zhou, Xuan Wang, Yingye Zheng, and Tianxi Cai.

    Graziano, Francesca / Valsecchi, Maria Grazia / Rebora, Paola

    Biometrical journal. Biometrische Zeitschrift

    2023  Volume 65, Issue 8, Page(s) e2300053

    Language English
    Publishing date 2023-07-20
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 131640-0
    ISSN 1521-4036 ; 0323-3847 ; 0006-3452
    ISSN (online) 1521-4036
    ISSN 0323-3847 ; 0006-3452
    DOI 10.1002/bimj.202300053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 1267: Show issues

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  3. Article ; Online: The predictive value and clinical use of the neurological pupillary index - Authors' reply.

    Galimberti, Stefania / Petrosino, Matteo / Rebora, Paola / Oddo, Mauro / Taccone, Fabio S / Citerio, Giuseppe

    The Lancet. Neurology

    2024  Volume 23, Issue 3, Page(s) 229–230

    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Letter
    ZDB-ID 2081241-3
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(23)00504-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5955: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Correction: Sampling strategies to evaluate the prognostic value of a new biomarker on a time-to-event end-point.

    Graziano, Francesca / Valsecchi, Maria Grazia / Rebora, Paola

    BMC medical research methodology

    2022  Volume 22, Issue 1, Page(s) 158

    Language English
    Publishing date 2022-06-01
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2041362-2
    ISSN 1471-2288 ; 1471-2288
    ISSN (online) 1471-2288
    ISSN 1471-2288
    DOI 10.1186/s12874-022-01627-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sampling strategies to evaluate the prognostic value of a new biomarker on a time-to-event end-point.

    Graziano, Francesca / Valsecchi, Maria Grazia / Rebora, Paola

    BMC medical research methodology

    2021  Volume 21, Issue 1, Page(s) 93

    Abstract: Background: The availability of large epidemiological or clinical data storing biological samples allow to study the prognostic value of novel biomarkers, but efficient designs are needed to select a subsample on which to measure them, for parsimony and ...

    Abstract Background: The availability of large epidemiological or clinical data storing biological samples allow to study the prognostic value of novel biomarkers, but efficient designs are needed to select a subsample on which to measure them, for parsimony and economical reasons. Two-phase stratified sampling is a flexible approach to perform such sub-sampling, but literature on stratification variables to be used in the sampling and power evaluation is lacking especially for survival data.
    Methods: We compared the performance of different sampling designs to assess the prognostic value of a new biomarker on a time-to-event endpoint, applying a Cox model weighted by the inverse of the empirical inclusion probability.
    Results: Our simulation results suggest that case-control stratified (or post stratified) by a surrogate variable of the marker can yield higher performances than simple random, probability proportional to size, and case-control sampling. In the presence of high censoring rate, results showed an advantage of nested case-control and counter-matching designs in term of design effect, although the use of a fixed ratio between cases and controls might be disadvantageous. On real data on childhood acute lymphoblastic leukemia, we found that optimal sampling using pilot data is greatly efficient.
    Conclusions: Our study suggests that, in our sample, case-control stratified by surrogate and nested case-control yield estimates and power comparable to estimates obtained in the full cohort while strongly decreasing the number of patients required. We recommend to plan the sample size and using sampling designs for exploration of novel biomarker in clinical cohort data.
    MeSH term(s) Biomarkers ; Case-Control Studies ; Child ; Cohort Studies ; Humans ; Prognosis ; Proportional Hazards Models ; Research Design
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-04-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041362-2
    ISSN 1471-2288 ; 1471-2288
    ISSN (online) 1471-2288
    ISSN 1471-2288
    DOI 10.1186/s12874-021-01283-0
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  6. Article ; Online: Intracranial pressure monitoring and unfavourable outcomes - Authors' reply.

    Citerio, Giuseppe / Robba, Chiara / Graziano, Francesca / Rebora, Paola

    The Lancet. Neurology

    2021  Volume 20, Issue 12, Page(s) 979

    MeSH term(s) Humans ; Intracranial Pressure ; Monitoring, Physiologic
    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2081241-3
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(21)00370-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5955: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The authors reply.

    Robba, Chiara / Rebora, Paola / Meyfroidt, Geert / Citerio, Giuseppe

    Critical care medicine

    2021  Volume 49, Issue 5, Page(s) e554–e555

    Language English
    Publishing date 2021-06-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: The role of frailty in COVID-19 patients.

    Bellelli, Giuseppe / Rebora, Paola / Citerio, Giuseppe

    Intensive care medicine

    2020  Volume 46, Issue 10, Page(s) 1958–1959

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Frailty ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06204-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1089: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study.

    Oddo, Mauro / Taccone, Fabio / Galimberti, Stefania / Rebora, Paola / Citerio, Giuseppe

    BMJ open

    2021  Volume 11, Issue 5, Page(s) e046948

    Abstract: Introduction: The pupillary examination is an important part of the neurological assessment, especially in the setting of acutely brain-injured patients, and pupillary abnormalities are associated with poor outcomes. Currently, the pupillary examination ...

    Abstract Introduction: The pupillary examination is an important part of the neurological assessment, especially in the setting of acutely brain-injured patients, and pupillary abnormalities are associated with poor outcomes. Currently, the pupillary examination is based on a visual, subjective and frequently inaccurate estimation. The use of automated infrared pupillometry to measure the pupillary light reflex can precisely quantify subtle changes in pupillary functions. The study aimed to evaluate the association between abnormal pupillary function, assessed by the Neurological Pupil Index (NPi), and long-term outcomes in patients with acute brain injury (ABI).
    Methods and analysis: The Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index study is a prospective, observational study including adult patients with ABI requiring admission at the intensive care unit. We aimed to recruit at least 420 patients including those suffering from traumatic brain injury or haemorrhagic strokes, over 12 months. The primary aim was to assess the relationship between NPi and 6-month mortality or poor neurological outcome, measured by the Extended Glasgow Outcome Score (GOS-E, poor outcome=GOS-E 1-4). Supervised and unsupervised methods and latent class mixed models will be used to identify patterns of NPi trajectories and Cox and logistic model to evaluate their association with outcome.
    Ethics and dissemination: The study has been approved by the institutional review board (Comitato Etico Brianza) on 16 July 2020. Approved protocol V.4.0 dated 10 March 2020. The results of this study will be published in peer-reviewed journals and presented at conferences.
    Trial registration number: NCT04490005.
    MeSH term(s) Adult ; Brain Injuries/complications ; Brain Injuries/diagnosis ; Cohort Studies ; Humans ; Multicenter Studies as Topic ; Observational Studies as Topic ; Prospective Studies ; Pupil ; Reflex, Pupillary
    Language English
    Publishing date 2021-05-11
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-046948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Suggestions to Improve Research on Motivational Interviewing for Heart Failure Self-care: Insights From Study Experiences.

    Caggianelli, Gabriele / Iovino, Paolo / Rebora, Paola / Ausili, Davide / Alvaro, Rosaria / Riegel, Barbara / Vellone, Ercole

    The Journal of cardiovascular nursing

    2022  Volume 37, Issue 5, Page(s) 437–438

    MeSH term(s) Heart Failure/therapy ; Humans ; Motivational Interviewing ; Self Care ; Self Efficacy
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 639335-4
    ISSN 1550-5049 ; 0889-4655
    ISSN (online) 1550-5049
    ISSN 0889-4655
    DOI 10.1097/JCN.0000000000000894
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2315: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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