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  1. Book: Impact of sleep and sleep disturbances on obesity and cancer

    Redline, Susan / Berger, Nathan A.

    (Energy balance and cancer ; 8)

    2014  

    Author's details Susan Redline ; Nathan A. Berger ed
    Series title Energy balance and cancer ; 8
    Collection
    Language English
    Size XIII, 239 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018143130
    ISBN 978-1-4614-9526-0 ; 9781461495277 ; 1-4614-9526-1 ; 146149527X
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Inflammation and Continuous Positive Airway Pressure Therapy: More Evidence of the Need for Better Sleep Apnea Phenotyping.

    Redline, Susan / Gottlieb, Daniel J

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 7, Page(s) 955–957

    MeSH term(s) Humans ; Continuous Positive Airway Pressure ; Proteomics ; Sleep Apnea Syndromes ; Sleep Apnea, Obstructive/therapy ; Cluster Analysis ; Inflammation
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202304-324ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Heritability and genetic correlations for sleep apnea, insomnia, and hypersomnia in a large clinical biobank.

    Cade, Brian E / Redline, Susan

    Sleep health

    2023  Volume 10, Issue 1S, Page(s) S157–S160

    Abstract: Rationale: Comorbid insomnia and sleep apnea is reported to have worse outcomes than either condition alone. The local genetic correlations of these disorders are unknown.: Objectives: To identify local genomic regions with heritability for ... ...

    Abstract Rationale: Comorbid insomnia and sleep apnea is reported to have worse outcomes than either condition alone. The local genetic correlations of these disorders are unknown.
    Objectives: To identify local genomic regions with heritability for clinically diagnosed sleep apnea and insomnia, and to identify local genetic correlations between these disorders and/or hypersomnia.
    Methods: Fifty thousand two hundred seventeen patients of European ancestry were examined. Global and local heritability and genetic correlations for independent regions were calculated, adjusting for obesity and other covariates.
    Results: Sleep apnea and insomnia were significantly globally heritable and had 118 and 168 genetic regions with local heritability p-values <.05, respectively. One region had a significant genetic correlation for sleep apnea and hypersomnia (p-value = 9.85 × 10
    Conclusions: Clinically diagnosed sleep apnea and insomnia have minimal shared genetic architecture, supporting genetically distinct comorbid insomnia and sleep apnea components. However, additional correlated regions may be identified with additional sample size and methodological improvements.
    MeSH term(s) Humans ; Sleep Initiation and Maintenance Disorders/epidemiology ; Sleep Initiation and Maintenance Disorders/genetics ; Sleep Apnea, Obstructive ; Biological Specimen Banks ; Sleep Apnea Syndromes/epidemiology ; Sleep Apnea Syndromes/genetics ; Disorders of Excessive Somnolence/epidemiology ; Disorders of Excessive Somnolence/genetics
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2813299-3
    ISSN 2352-7226 ; 2352-7218
    ISSN (online) 2352-7226
    ISSN 2352-7218
    DOI 10.1016/j.sleh.2023.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Skip Polysomnography Before Adenotonsillectomy for Snoring?-Reply.

    Mitchell, Ron B / Baldassari, Cristina M / Redline, Susan

    JAMA otolaryngology-- head & neck surgery

    2024  

    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2024.0584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: The social epidemiology of sleep

    Duncan, Dustin T. / Kawachi, Ichirō / Redline, Susan

    2019  

    Author's details edited by Dustin T. Duncan, Ichiro Kawachi and Susan Redline
    Keywords Sleep ; Sleep/Social aspects ; Epidemiology
    Subject code 613.794
    Language English
    Size XI, 453 Seiten, Illustrationen
    Publisher Oxford University Press
    Publishing place New York
    Publishing country Great Britain
    Document type Book
    Note Enthält Literaturverzeichnis (Seiten 421-429) und Index (Seiten 435-453)
    HBZ-ID HT020355876
    ISBN 978-0-19-093044-8 ; 978-0-19-093043-1 ; 0-19-093044-6 ; 0-19-093043-8
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Disparities in Sleep-Disordered Breathing: Upstream Risk Factors, Mechanisms, and Implications.

    Gueye-Ndiaye, Seyni / Williamson, Ariel A / Redline, Susan

    Clinics in chest medicine

    2023  Volume 44, Issue 3, Page(s) 585–603

    Abstract: Sleep-disordered breathing (SDB) refers to a spectrum of disorders ranging from habitual snoring without frank episodes of obstructed breathing or desaturation during sleep to obstructive sleep apnea, where apneas and hypopneas repetitively occur with ... ...

    Abstract Sleep-disordered breathing (SDB) refers to a spectrum of disorders ranging from habitual snoring without frank episodes of obstructed breathing or desaturation during sleep to obstructive sleep apnea, where apneas and hypopneas repetitively occur with resultant intermittent hypoxia, arousal, and sleep disruption. Disparities in SDB reflect its overall high prevalence in children and adults from racially and ethnically minoritized or low socioeconomic status backgrounds coupled with high rates of underdiagnosis and suboptimal treatment.
    MeSH term(s) Adult ; Child ; Humans ; Sleep Apnea Syndromes/epidemiology ; Sleep Apnea Syndromes/therapy ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/therapy ; Snoring/etiology ; Snoring/complications ; Risk Factors ; Prevalence
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 447455-7
    ISSN 1557-8216 ; 0272-5231
    ISSN (online) 1557-8216
    ISSN 0272-5231
    DOI 10.1016/j.ccm.2023.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Screening for Obstructive Sleep Apnea: Implications for the Sleep Health of the Population.

    Redline, Susan

    JAMA

    2017  Volume 317, Issue 4, Page(s) 368–370

    MeSH term(s) Humans ; Polysomnography ; Sleep ; Sleep Apnea, Obstructive/diagnosis
    Language English
    Publishing date 2017--24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2016.18630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Obstructive sleep apnoea heterogeneity and cardiovascular disease.

    Redline, Susan / Azarbarzin, Ali / Peker, Yüksel

    Nature reviews. Cardiology

    2023  Volume 20, Issue 8, Page(s) 560–573

    Abstract: Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease (CVD), and is therefore important to consider in the prevention and ... ...

    Abstract Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease (CVD), and is therefore important to consider in the prevention and management of CVD. Observational studies indicate that OSA is a risk factor for incident hypertension, poorly controlled blood pressure, stroke, myocardial infarction, heart failure, cardiac arrhythmias, sudden cardiac death and all-cause death. However, clinical trials have not provided consistent evidence that treatment with continuous positive airway pressure (CPAP) improves cardiovascular outcomes. These overall null findings might be explained by limitations in trial design and low levels of adherence to CPAP. Studies have also been limited by the failure to consider OSA as a heterogeneous disorder that consists of multiple subtypes resulting from variable contributions from anatomical, physiological, inflammatory and obesity-related risk factors, and resulting in different physiological disturbances. Novel markers of sleep apnoea-associated hypoxic burden and cardiac autonomic response have emerged as predictors of OSA-related susceptibility to adverse health outcomes and treatment response. In this Review, we summarize our understanding of the shared risk factors and causal links between OSA and CVD and emerging knowledge on the heterogeneity of OSA. We discuss the varied mechanistic pathways that result in CVD that also vary across subgroups of OSA, as well as the potential role of new biomarkers for CVD risk stratification.
    MeSH term(s) Humans ; Cardiovascular Diseases/prevention & control ; Cardiovascular System ; Hypertension/complications ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/therapy ; Heart ; Hypoxia
    Language English
    Publishing date 2023-03-10
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2490375-9
    ISSN 1759-5010 ; 1759-5002
    ISSN (online) 1759-5010
    ISSN 1759-5002
    DOI 10.1038/s41569-023-00846-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reply to Meira e Cruz

    Li, Xiaoyu / Redline, Susan

    American journal of respiratory and critical care medicine

    2021  Volume 203, Issue 12, Page(s) 1585–1586

    MeSH term(s) Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Humans ; Polysomnography ; Sleep Apnea Syndromes/complications ; Sleep Apnea Syndromes/epidemiology ; Sleep Initiation and Maintenance Disorders/complications ; Sleep Initiation and Maintenance Disorders/epidemiology
    Language English
    Publishing date 2021-03-29
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202103-0558LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Response.

    Huang, Tianyi / Redline, Susan

    Chest

    2021  Volume 159, Issue 6, Page(s) 2516–2517

    Language English
    Publishing date 2021-05-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.02.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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