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  1. Article ; Online: Living in US rural areas could be hazardous to your health.

    Reed, James

    BMJ (Clinical research ed.)

    2022  Volume 378, Page(s) o1847

    MeSH term(s) Humans ; Rural Health ; Rural Population ; Urban Population
    Language English
    Publishing date 2022-07-26
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.o1847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Chest radiology

    Reed, James C.

    plain film patterns and differential diagnosis

    2011  

    Author's details James C. Reed
    Keywords Radiography, Thoracic ; Diagnosis, Differential ; Respiratory Tract Diseases / radiography
    Language English
    Size XXIV, 455 S. : zahlr. Ill., graph. Darst.
    Edition 6. ed.
    Publisher Elsevier Mosby
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT016636425
    ISBN 978-1-4377-2345-8 ; 1-4377-2345-4
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Obstetrics.

    Reed, James M

    The Journal of comparative medicine and veterinary archives

    2022  Volume 23, Issue 7, Page(s) 416–418

    Language English
    Publishing date 2022-10-24
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Chest radiology

    Reed, James C.

    plain film patterns and differential diagnosis

    2003  

    Author's details James C. Reed
    Keywords Thoracic Radiography ; Diagnosis, Differential
    Language English
    Size XVII, 495 S. : zahlr. Ill., graph. Darst.
    Edition 5. ed.
    Publisher Mosby
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    HBZ-ID HT013807846
    ISBN 0-323-02617-6 ; 978-0-323-02617-8
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Observations on Variola, Varicella, and Modified Small-Pox.

    Reed, James

    Edinburgh medical and surgical journal

    2018  Volume 18, Issue 71, Page(s) 184–191

    Language English
    Publishing date 2018-10-17
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2793596-6
    ISSN 0963-4932
    ISSN 0963-4932
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Victim selection patterns of community-residing child molesters identified by a nationwide youth-serving organization.

    Warren, Janet I / Reed, James

    Behavioral sciences & the law

    2021  Volume 39, Issue 3, Page(s) 307–327

    Abstract: The current study examines data extracted from revocation files of a national youth-serving organization (YSO) involving 7819 revoked individuals and 12,254 alleged child victims to better understand victim selection patterns of community-residing child ... ...

    Abstract The current study examines data extracted from revocation files of a national youth-serving organization (YSO) involving 7819 revoked individuals and 12,254 alleged child victims to better understand victim selection patterns of community-residing child molesters. These data demonstrate consistent patterns of victim selection based upon the age, gender, and YSO affiliation of each victim. We created two variables to explore whether the revoked individual was "likely pedophilic (LP)" or a "mixed offender (MO)" based upon their behaviors and patterns of victim selection. Compared with the non-LPs and non-MOs, LPs and MOs had more known victims, were more often involved in other YSOs, and were more likely to have had contact with law enforcement. We utilized a public health perspective to interpret these findings, suggesting that child sexual abuse in YSOs reflects a societal problem that is not a unique phenomenon specific to programs offering services to youth.
    MeSH term(s) Adolescent ; Child ; Child Abuse ; Child Abuse, Sexual ; Crime Victims ; Criminals ; Family ; Humans
    Language English
    Publishing date 2021-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 232671-1
    ISSN 1099-0798 ; 0735-3936
    ISSN (online) 1099-0798
    ISSN 0735-3936
    DOI 10.1002/bsl.2507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Chest radiology

    Reed, James C.

    plain film patterns and differential diagnosis

    1997  

    Author's details James C. Reed
    Keywords Thoracic Radiography ; Diagnosis, Differential
    Language English
    Size XX, 473 S. : zahlr. Ill., graph. Darst.
    Edition 4. ed.
    Publisher Mosby
    Publishing place St. Louis u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007717976
    ISBN 0-8151-7122-6 ; 978-0-8151-7122-5
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes.

    Reed, James R / Guidry, Jessie J / Eyer, Marilyn / Backes, Wayne L

    Drug metabolism and disposition: the biological fate of chemicals

    2023  Volume 51, Issue 9, Page(s) 1196–1206

    Abstract: Liver cytochrome P450s (CYPs) of the endoplasmic reticulum (ER) are involved in the metabolism of exogenous and endogenous chemicals. The ER is not uniform, but possesses ordered lipid microdomains containing higher levels of saturated fatty acids, ... ...

    Abstract Liver cytochrome P450s (CYPs) of the endoplasmic reticulum (ER) are involved in the metabolism of exogenous and endogenous chemicals. The ER is not uniform, but possesses ordered lipid microdomains containing higher levels of saturated fatty acids, sphingomyelin, and cholesterol and disordered regions containing higher levels of polyunsaturated fatty acid chains. The various forms of drug-metabolizing P450s partition to either the ordered or disordered lipid microdomains with different degrees of specificity. P450s readily form complexes with ER-resident proteins, including other forms of P450. This study aims to ascertain whether lipid microdomain localization influences protein-P450 interactions in rat liver microsomes. Thus, liver microsomes were co-immunoprecipitated with CYP1A2-specific and CYP3A-specific antibodies, and the co-immunoprecipitating proteins were identified by liquid chromatography mass spectrometry proteomic analysis. These two P450s preferentially partition to ordered and disordered microdomains, respectively. More than 100 proteins were co-immunoprecipitated with each P450. Segregation of proteins into different microdomains did not preclude their interaction. However, CYP3A interacted broadly with proteins from ordered microdomains, whereas CYP1A2 reacted with a limited subset of these proteins. This is consistent with the concept of lipid raft heterogeneity and may indicate that CYP1A2 is targeted to a specific type of lipid raft. Although many of the interacting proteins for both P450s were other-drug metabolizing enzymes, other interactions were also evident. The consistent CYP3A binding partners were predominantly involved in phase I/II drug metabolism; however, CYP1A2 interacted not only with xenobiotic metabolizing enzymes, but also with enzymes involved in diverse cellular responses such as ER stress and protein folding. SIGNIFICANCE STATEMENT: This work describes the protein interactomes in rat liver microsomes of two important cytochromes P450s (CYP1A2 and CYP3A) in drug metabolism and describes the relationship of the interacting proteins to lipid microdomain distribution.
    MeSH term(s) Rats ; Animals ; Cytochrome P-450 CYP1A2/metabolism ; Microsomes, Liver/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Proteomics ; Cytochrome P-450 Enzyme System/metabolism ; Lipids
    Chemical Substances Cytochrome P-450 CYP1A2 (EC 1.14.14.1) ; Cytochrome P-450 CYP3A (EC 1.14.14.1) ; Cytochrome P-450 Enzyme System (9035-51-2) ; Lipids
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 186795-7
    ISSN 1521-009X ; 0090-9556
    ISSN (online) 1521-009X
    ISSN 0090-9556
    DOI 10.1124/dmd.123.001287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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