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  1. Book: Computational approaches in metabolic engineering

    Reed, Jennifer L.

    (Journal of biomedicine and biotechnology ; 2010, Spec. iss.)

    2010  

    Author's details guest ed.: Jennifer L. Reed
    Series title Journal of biomedicine and biotechnology ; 2010, Spec. iss.
    Journal of biomedicine & biotechnology
    Collection Journal of biomedicine & biotechnology
    Language English
    Size Getr. Zählung : Ill., graph. Darst.
    Publisher Hindawi
    Publishing place S.l.
    Publishing country United States
    Document type Book
    HBZ-ID HT016906979
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 5540 -2010,Spec.iss.- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated?

    Buckley, John P / Terada, Tasuku / Lion, Anna / Reed, Jennifer L

    European journal of applied physiology

    2024  

    Abstract: Purpose: Moderate-intensity aerobic exercise is safe and beneficial in atrial fibrillation (AF) and coronary heart disease (CHD). Irregular or rapid heart rates (HR) in AF and other heart conditions create a challenge to using HR to monitor exercise ... ...

    Abstract Purpose: Moderate-intensity aerobic exercise is safe and beneficial in atrial fibrillation (AF) and coronary heart disease (CHD). Irregular or rapid heart rates (HR) in AF and other heart conditions create a challenge to using HR to monitor exercise intensity. The purpose of this study was to assess the potential of breathing frequency (BF) to monitor exercise intensity in people with AF and CHD without AF.
    Methods: This observational study included 30 AF participants (19 Male, 70.7 ± 8.7 yrs) and 67 non-AF CHD participants (38 Male, 56.9 ± 11.4 yrs). All performed an incremental maximal exercise test with pulmonary gas exchange.
    Results: Peak aerobic power in AF (
    Conclusion: With the use of wearable technologies on the rise, that now include BF, this first study provides an encouraging potential for BF to be used in AF and CHD. As the supporting data are based on incremental ramp protocol results, further research is required to assess BF validity to manage exercise intensity during longer bouts of exercise.
    Language English
    Publishing date 2024-05-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-024-05487-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Subdural Fluid and Near-Miss Hypertension in a Previously Healthy Infant.

    Reel, Sarah Martin / Burkhardt, Mary Carol / Reed, Jennifer L

    Clinical pediatrics

    2023  Volume 62, Issue 11, Page(s) 1436–1439

    MeSH term(s) Infant ; Humans ; Near Miss, Healthcare ; Infant Mortality ; Hypertension/etiology
    Language English
    Publishing date 2023-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231157314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 454: Show issues Location:
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  4. Article ; Online: Commentary: Is Wearable Fitness Technology a Medically Approved Device? Yes and No.

    Scheid, Jennifer L / Reed, Jennifer L / West, Sarah L

    International journal of environmental research and public health

    2023  Volume 20, Issue 13

    Abstract: Wearable technologies, i.e., activity trackers and fitness watches, are extremely popular and have been increasingly integrated into medical research and clinical practice. To assist in optimizing health, wellness, or medical care, these devices require ... ...

    Abstract Wearable technologies, i.e., activity trackers and fitness watches, are extremely popular and have been increasingly integrated into medical research and clinical practice. To assist in optimizing health, wellness, or medical care, these devices require collaboration between researchers, healthcare providers, and wearable technology companies in order to clarify their clinical capabilities and educate consumers on the utilities and limitations of the wide-ranging wearable devices. Interestingly, activity trackers and fitness watches often track both health/wellness and medical information within the same device. In this commentary, we will focus our discussions regarding wearable technology on (1) defining and explaining the technical differences between tracking health, wellness, and medical information; (2) providing examples of health and wellness compared to medical tracking; (3) describing the potential medical benefits of wearable technology and its applications in clinical populations; and (4) elucidating the potential risks of wearable technology. We conclude that while wearable devices are powerful and informative tools, further research is needed to improve its clinical applications.
    MeSH term(s) Wearable Electronic Devices ; Fitness Trackers ; Exercise ; Biomedical Research ; Technology
    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20136230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Is it time to update standard cardiac rehabilitation programming? The evidence suggests we must go above and beyond.

    Reed, Jennifer L

    International journal of cardiology

    2018  Volume 255, Page(s) 229–230

    MeSH term(s) Cardiac Rehabilitation ; Humans
    Language English
    Publishing date 2018--15
    Publishing country Netherlands
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2018.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
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  6. Article ; Online: The Effects of Different Exercise Modalities and Intensities on Arterial Stiffness in Patients With Coronary Artery Disease.

    Marçal, Isabela R / Cotie, Lisa M / Ribeiro, Indyanara / Reed, Jennifer L

    Journal of cardiopulmonary rehabilitation and prevention

    2023  Volume 43, Issue 5, Page(s) 384–385

    MeSH term(s) Humans ; Coronary Artery Disease ; Vascular Stiffness ; Exercise
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2272063-7
    ISSN 1932-751X ; 1932-7501
    ISSN (online) 1932-751X
    ISSN 1932-7501
    DOI 10.1097/HCR.0000000000000799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1998: Show issues Location:
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  7. Article ; Online: High-Intensity Interval Training vs Moderate-Intensity Continuous Training for Women Undergoing Cardiovascular Rehabilitation.

    Terada, Tasuku / Vidal-Almela, Sol / Reed, Jennifer L

    JAMA cardiology

    2022  Volume 7, Issue 8, Page(s) 875

    MeSH term(s) Cardiac Rehabilitation ; Exercise Therapy ; Female ; High-Intensity Interval Training ; Humans ; Quality of Life
    Language English
    Publishing date 2022-06-15
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2022.1476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An Evaluation of Device-Measured Physical Activity Levels of Patients With Nonpermanent Atrial Fibrillation.

    Reed, Jennifer L / Blanchard, Chris M / Parkash, Ratika

    Journal of cardiopulmonary rehabilitation and prevention

    2021  Volume 41, Issue 6, Page(s) 440–442

    MeSH term(s) Anticoagulants ; Atrial Fibrillation ; Exercise ; Humans ; Stroke ; Treatment Outcome
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-11-02
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2272063-7
    ISSN 1932-751X ; 1932-7501
    ISSN (online) 1932-751X
    ISSN 1932-7501
    DOI 10.1097/HCR.0000000000000640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1998: Show issues Location:
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  9. Article ; Online: Meeting the Needs of Women in Cardiac Rehabilitation.

    Way, Kimberley L / Reed, Jennifer L

    Circulation

    2019  Volume 139, Issue 10, Page(s) 1247–1248

    MeSH term(s) Cardiac Rehabilitation/methods ; Cardiovascular Diseases/physiopathology ; Cardiovascular Diseases/psychology ; Cardiovascular Diseases/therapy ; Exercise Therapy ; Female ; Health Services Needs and Demand ; Health Status ; Health Status Disparities ; Healthcare Disparities ; Humans ; Mental Health ; Needs Assessment ; Risk Factors ; Sex Factors ; Treatment Outcome
    Language English
    Publishing date 2019-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.118.037754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Introduction of NADH-dependent nitrate assimilation in Synechococcus sp. PCC 7002 improves photosynthetic production of 2-methyl-1-butanol and isobutanol.

    Purdy, Hugh M / Pfleger, Brian F / Reed, Jennifer L

    Metabolic engineering

    2021  Volume 69, Page(s) 87–97

    Abstract: Cyanobacteria hold promise for renewable chemical production due to their photosynthetic nature, but engineered strains frequently display poor production characteristics. These difficulties likely arise in part due to the distinctive photoautotrophic ... ...

    Abstract Cyanobacteria hold promise for renewable chemical production due to their photosynthetic nature, but engineered strains frequently display poor production characteristics. These difficulties likely arise in part due to the distinctive photoautotrophic metabolism of cyanobacteria. In this work, we apply a genome-scale metabolic model of the cyanobacteria Synechococus sp. PCC 7002 to identify strain designs accounting for this unique metabolism that are predicted to improve the production of various biofuel alcohols (e.g. 2-methyl-1-butanol, isobutanol, and 1-butanol) synthesized via an engineered biosynthesis pathway. Using the model, we identify that the introduction of a large, non-native NADH-demand into PCC 7002's metabolic network is predicted to enhance production of these alcohols by promoting NADH-generating reactions upstream of the production pathways. To test this, we construct strains of PCC 7002 that utilize a heterologous, NADH-dependent nitrite reductase in place of the native, ferredoxin-dependent enzyme to create an NADH-demand in the cells when grown on nitrate-containing media. We find that photosynthetic production of both isobutanol and 2-methyl-1-butanol is significantly improved in the engineered strain background relative to that in a wild-type background. We additionally identify that the use of high-nutrient media leads to a substantial prolongment of the production curve in our alcohol production strains. The metabolic engineering strategy identified and tested in this work presents a novel approach to engineer cyanobacterial production strains that takes advantage of a unique aspect of their metabolism and serves as a basis on which to further develop strains with improved production of these alcohols and related products.
    MeSH term(s) 1-Butanol/metabolism ; Butanols ; NAD/genetics ; NAD/metabolism ; Nitrates/metabolism ; Synechococcus/genetics ; Synechococcus/metabolism
    Chemical Substances Butanols ; Nitrates ; NAD (0U46U6E8UK) ; isobutyl alcohol (56F9Z98TEM) ; 1-Butanol (8PJ61P6TS3)
    Language English
    Publishing date 2021-11-10
    Publishing country Belgium
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1470383-x
    ISSN 1096-7184 ; 1096-7176
    ISSN (online) 1096-7184
    ISSN 1096-7176
    DOI 10.1016/j.ymben.2021.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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