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  1. Article: Diagnosis and management of acute aortic dissection in the emergency department.

    Reed, Matthew J

    British journal of hospital medicine (London, England : 2005)

    2024  Volume 85, Issue 4, Page(s) 1–9

    Abstract: Acute aortic dissection is often misdiagnosed as a result of its atypical presentations. It affects 4000 patients a year in the UK of all ages, not just older patients, with increasing numbers of cases expected in the future because of the ageing ... ...

    Abstract Acute aortic dissection is often misdiagnosed as a result of its atypical presentations. It affects 4000 patients a year in the UK of all ages, not just older patients, with increasing numbers of cases expected in the future because of the ageing population. Dissection of the aortic wall leads to sudden, severe pain, and commonly end-organ symptoms which must be recognised. Acute aortic dissection can be challenging to diagnose in the emergency department because of the multitude of possible presentations and the need for selective testing with Computed Tomography Angiography (CTA). Clinicians often miss acute aortic dissection because it is not considered in the differential diagnosis, and the challenge lies in identifying acute aortic dissection in a sea of complaints of chest, back and abdominal pain. There are several ways to improve diagnosis, including awareness campaigns, better education about patients in which to consider acute aortic dissection, and improved detection strategies including which patients should receive CTA. Clinical decision tools and biomarkers could help, but further research is required and is a research focus in emergency medicine. Once diagnosed, blood pressure control, analgesia and urgent surgery or transfer to enable this to occur with minimal delay is required.
    MeSH term(s) Humans ; Aortic Dissection/diagnosis ; Aortic Dissection/therapy ; Emergency Service, Hospital ; Computed Tomography Angiography ; Acute Disease ; Aortic Aneurysm/diagnosis ; Aortic Aneurysm/therapy ; Diagnosis, Differential
    Language English
    Publishing date 2024-05-06
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2023.0366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Changes in transfusion practice in Scotland between June 2013 and December 2019.

    Reed, Matthew J

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2023  Volume 30, Issue 2, Page(s) 143–145

    MeSH term(s) Humans ; Blood Transfusion ; Scotland
    Language English
    Publishing date 2023-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Survey of current policy regarding the recognition and management of acute aortic syndrome in Great Britain.

    Alawiye, Salma / Cooper, Graham / Fowler, Catherine / Reed, Matthew J

    Emergency medicine journal : EMJ

    2024  Volume 41, Issue 3, Page(s) 151–152

    MeSH term(s) Humans ; United Kingdom ; Aortic Dissection ; Acute Aortic Syndrome ; Acute Disease ; Emergency Service, Hospital
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emermed-2023-213376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Targeted HIV screening in the emergency department.

    Spagnolello, Ornella / Reed, Matthew J

    Internal and emergency medicine

    2021  Volume 16, Issue 5, Page(s) 1273–1287

    Abstract: Despite considerable improvement in human immunodeficiency virus (HIV) knowledge and treatment in the last 3 decades, the overall number of people living with HIV (PLHIV) is still rising with up to one quarter being unaware of their HIV status. Early HIV ...

    Abstract Despite considerable improvement in human immunodeficiency virus (HIV) knowledge and treatment in the last 3 decades, the overall number of people living with HIV (PLHIV) is still rising with up to one quarter being unaware of their HIV status. Early HIV diagnosis and treatment prolongs life, reduces transmission, improves quality of life, and is a cost-effective public health intervention. The emergency department (ED) sees a large number of patients from marginalized and traditionally underserved populations in whom HIV is known to be more prevalent and who may not attend traditional services because of either cultural reasons or because of a chaotic lifestyle. This article discusses the two main approaches to screening; 'Opt-out' screening offers testing routinely in all clinical settings, and 'Targeted' screening offers testing to individuals presenting with indicator conditions. There are many studies of 'Opt-out' ED HIV screening in urban areas of high-HIV prevalence. However, little is known about the effectiveness of 'targeted' HIV screening, especially in areas of low prevalence. This review discusses the background to HIV screening in the ED and reviews the evidence around 'targeted' HIV screening in adult EDs in different HIV prevalence settings, concluding that targeted HIV screening at the ED can be impactful, cost-effective, and well accepted in the ED population, but its long-term implementation requires extra funding and increased staffing resource limiting its application in low resource setting. Despite most evidence being from areas of high-HIV prevalence, targeted screening might also be appropriate in low-HIV prevalence areas.
    MeSH term(s) Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; Humans ; Mass Screening/methods ; Mass Screening/standards ; Mass Screening/statistics & numerical data ; Prevalence ; Public Opinion
    Language English
    Publishing date 2021-02-07
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-021-02648-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An evaluation of patient ownership and use and acceptability of smartphone technology within the emergency department.

    Summers, Alasdair M / Reed, Matthew J

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2018  Volume 25, Issue 3, Page(s) 224–225

    MeSH term(s) Adult ; Age Factors ; Aged ; Emergency Service, Hospital/trends ; Humans ; Middle Aged ; Ownership ; Patient Acceptance of Health Care ; Patient Compliance/statistics & numerical data ; Scotland ; Sex Factors ; Smartphone/utilization ; Surveys and Questionnaires ; Urban Population ; Young Adult
    Language English
    Publishing date 2018-04-23
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A proper 24/7 emergency care service is needed in the NHS.

    Reed, Matthew J

    BMJ (Clinical research ed.)

    2013  Volume 346, Page(s) f1871

    MeSH term(s) Emergency Medical Services ; England ; Humans ; State Medicine
    Language English
    Publishing date 2013-03-28
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.f1871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Unscheduled care pathways in patients with myocardial infarction in Scotland.

    Hodgins, Peter / McMinn, Megan / Shah, Anoop / Reed, Matthew J / Mercer, Stewart / Guthrie, Bruce

    Heart (British Cardiac Society)

    2022  Volume 108, Issue 14, Page(s) 1129–1136

    Abstract: Objective: Treatment of acute myocardial infarction (MI) requires rapid transfer of people with chest pain to hospital, however, unscheduled care pathways vary in their directness (the minimal number of contacts to hospital admission). The aim was to ... ...

    Abstract Objective: Treatment of acute myocardial infarction (MI) requires rapid transfer of people with chest pain to hospital, however, unscheduled care pathways vary in their directness (the minimal number of contacts to hospital admission). The aim was to examine unscheduled care pathways and the associations with mortality in people admitted with MI.
    Methods: Retrospective population study of all people admitted to Scottish hospitals with a diagnosis of MI between 1 January 2015 and 31 December 2017. Linked data for all National Health Service Scotland unscheduled care services (NHS24 telephone triage service, primary care out of hours, ambulance, emergency department (ED)) was used to define continuous unscheduled care pathways (pathways), which were categorised by initial contact, and whether they were 'direct' (had minimum number of contacts between first contact and admission). Analysis estimated ORs and 95% CIs in adjusted models in which all covariates were included.
    Results: 26 325 people admitted with MI (63.1% men, 61.6% aged 65+ years), of whom 5.6% died from coronary heart disease within 28 days. For 47.0%, the first unscheduled care contact was ambulance, 23.3% attended ED directly and 18.7% called telephone triage. 92.1% of pathways were direct. Pathways starting with telephone triage were more likely to be indirect compared with other initial contacts (adjusted OR (aOR) 1.97, 95% CI 1.61 to 2.40). Compared to direct pathways, indirect pathways starting with telephone triage were associated with higher mortality (aOR 1.97, 95% CI 1.61 to 2.40) as were indirect pathways starting with another service (aOR 1.55, 95% CI 1.19 to 2.01), but not direct pathways starting with telephone triage (aOR 0.87, 95% CI 0.74 to 1.02).
    Conclusion: Unscheduled care pathways leading to admission with MI in Scotland are usually direct, but those starting with telephone triage were more commonly indirect. Those indirect pathways were associated with higher mortality.
    MeSH term(s) Critical Pathways ; Emergency Service, Hospital ; Female ; Humans ; Male ; Myocardial Infarction/diagnosis ; Myocardial Infarction/therapy ; Retrospective Studies ; State Medicine ; Triage
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2021-320614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pulmonary embolism management in the emergency department.

    Serebriakoff, Philippa / Cafferkey, John / de Wit, Kerstin / Horner, Daniel E / Reed, Matthew J

    Emergency medicine journal : EMJ

    2022  

    Abstract: Pulmonary embolism (PE) can present with a range of severity. Prognostic risk stratification is important for efficacious and safe management. This second of two review articles discusses the management of high-, intermediate- and low-risk PE. We discuss ...

    Abstract Pulmonary embolism (PE) can present with a range of severity. Prognostic risk stratification is important for efficacious and safe management. This second of two review articles discusses the management of high-, intermediate- and low-risk PE. We discuss strategies to identify patients suitable for urgent outpatient care in addition to identification of patients who would benefit from thrombolysis. We discuss specific subgroups of patients where optimal treatment differs from the usual approach and identify emerging management paradigms exploring new therapies and subgroups.
    Language English
    Publishing date 2022-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emermed-2021-212001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The clinical effectiveness of the STUMBL score for the management of ED patients with blunt chest trauma compared to clinical evaluation alone.

    Callisto, Elena / Costantino, Giorgio / Tabner, Andrew / Kerslake, Dean / Reed, Matthew J

    Internal and emergency medicine

    2022  Volume 17, Issue 6, Page(s) 1785–1793

    Abstract: The STUMBL (STUdy of the Management of BLunt chest wall trauma) score is a new prognostic score to assist ED (Emergency Department) decision making in the management of blunt chest trauma. This is a retrospective cohort chart review study conducted in a ... ...

    Abstract The STUMBL (STUdy of the Management of BLunt chest wall trauma) score is a new prognostic score to assist ED (Emergency Department) decision making in the management of blunt chest trauma. This is a retrospective cohort chart review study conducted in a UK University Hospital ED seeing 120,000 patients a year, comparing its performance characteristics to ED clinician judgement. All blunt chest trauma patients that presented to our ED over a 6-month period were included. Patients were excluded if age < 18, if they had immediate life-threatening injury, required critical care admission for other injuries or in case of missing identification data. Primary endpoint was complication defined as any of lower respiratory tract infection, pulmonary consolidation, empyema, pneumothorax, haemothorax, splenic or hepatic injury and 30-day mortality. Clinician judgement (clinician decision to admit) and STUMBL score were compared using the receiver-operating curve (ROC) and sensitivity analysis. Three hundred and sixty-nine patients were included. ED clinicians admitted 95 of 369 patients. ED clinician decision to admit had a sensitivity of 83.9% and specificity of 86.0% for predicting complications. STUMBL score ≥ 11 had a sensitivity of 79.0% and specificity of 77.9% for the same and would have led to 117 of 369 patients being admitted. Area under the curve (AUC) of STUMBL score and ED clinician decision to admit was 0.84 (95% CI 0.78-0.90) and 0.85 (95% CI 0.79-0.91), respectively. Our findings show that a STUMBL score ≥ 11 performs no better than ED clinician judgement and leads to more patients being admitted to hospital.
    MeSH term(s) Hemothorax ; Humans ; Injury Severity Score ; Retrospective Studies ; Thoracic Injuries/complications ; Thoracic Injuries/diagnosis ; Thoracic Injuries/therapy ; Treatment Outcome ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/therapy
    Language English
    Publishing date 2022-06-23
    Publishing country Italy
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03001-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Journal update monthly top five.

    Clarke, Benjamin / Alawiye, Salma / Anderson, Rory / Moceivei, Clare / Cox, Thomas James / Sharpe, Joseph / Reed, Matthew J / Jafar, Anisa Jabeen Nasir

    Emergency medicine journal : EMJ

    2023  Volume 40, Issue 6, Page(s) 466–467

    Language English
    Publishing date 2023-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emermed-2023-213300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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