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  1. Article: Minimal deviation melanoma. Borderline and intermediate melanocytic neoplasia.

    Reed, R J

    Clinics in laboratory medicine

    2000  Volume 20, Issue 4, Page(s) 745–758

    Abstract: In the concept of MDM, the term melanoma has been reserved for lesions showing a vertical growth component. Vertical growth, divorced from any prognostic implications, is simply a morphologic designation. Such a maneuver also serves to validate the ... ...

    Abstract In the concept of MDM, the term melanoma has been reserved for lesions showing a vertical growth component. Vertical growth, divorced from any prognostic implications, is simply a morphologic designation. Such a maneuver also serves to validate the category of MDM, although it might then be inappropriate to characterize such lesions as melanoma. From my view, the modifier "minimal deviation" takes the onus of prognosis out of the equation. For common melanomas, size of a vertical growth component has relativity to prognosis. It is unlikely that, in comparable size-ranges, the MDM have a more aggressive nature than the common melanoma. It seems appropriate to propose that MDM measuring less than 1.5 mm in vertical dimensions could be characterized as melanocytic neoplasia of indeterminant malignant potential. Those less than 1 mm in vertical dimensions would be borderline variants and those in the range of 1 to 1.5 mm would be intermediate examples. Those greater than 1.5 mm could be characterized as melanocytic neoplasias of indeterminant (uncertain) malignant potential without additional qualifications.
    MeSH term(s) Diagnosis, Differential ; Humans ; Melanoma/classification ; Melanoma/pathology ; Nevus, Pigmented/classification ; Nevus, Pigmented/pathology ; Phenotype ; Skin Neoplasms/classification ; Skin Neoplasms/pathology
    Language English
    Publishing date 2000-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604580-7
    ISSN 1557-9832 ; 0272-2712
    ISSN (online) 1557-9832
    ISSN 0272-2712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Dimensionalities: borderline and intermediate melanocytic neoplasia.

    Reed, R J

    Human pathology

    1999  Volume 30, Issue 5, Page(s) 521–524

    Abstract: The concept of minimal deviation melanoma is presented in diagrammatic form. In this approach, the precursors of melanoma are presented as having two dimensions and melanomas as having three dimensions. In turn, the relativity between dimensionalities ... ...

    Abstract The concept of minimal deviation melanoma is presented in diagrammatic form. In this approach, the precursors of melanoma are presented as having two dimensions and melanomas as having three dimensions. In turn, the relativity between dimensionalities and recommendations for treatment (as indirect correlates of prognostications) provides guidelines for the structuring of two major boundaries along the axis of the diagram. Finally, the domains defined by the two boundaries include borderline lesions, intermediate lesions, and "real melanomas." The lesions in the borderline and intermediate categories qualify as melanocytic neoplasias of indeterminant malignant potential; in these two categories, the predictability of metastases hardly justifies the use of the designation, malignant melanoma.
    MeSH term(s) Diagnosis, Differential ; Humans ; Melanoma/pathology ; Skin Neoplasms/pathology
    Language English
    Publishing date 1999-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/s0046-8177(99)90194-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Atypical spitz nevus/tumor.

    Reed, R J

    Human pathology

    1999  Volume 30, Issue 12, Page(s) 1523–1526

    MeSH term(s) Humans ; Nevus, Epithelioid and Spindle Cell/diagnosis ; Nevus, Epithelioid and Spindle Cell/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology
    Language English
    Publishing date 1999-12
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/s0046-8177(99)90180-6
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  4. Article: Melanoma in situ: images, segments, appellations, and implications.

    Reed, R J

    Human pathology

    1998  Volume 29, Issue 1, Page(s) 1–3

    MeSH term(s) Cell Transformation, Neoplastic ; Disease Progression ; Humans ; Melanoma/classification ; Melanoma/pathology ; Precancerous Conditions/pathology ; Skin Neoplasms/classification ; Skin Neoplasms/pathology ; Terminology as Topic
    Language English
    Publishing date 1998-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/s0046-8177(98)90381-1
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  5. Article: A good proposal?

    Reed, R J

    The American Journal of dermatopathology

    1995  Volume 17, Issue 1, Page(s) 104

    MeSH term(s) Dermatology ; Pathology ; Peer Review ; Publishing
    Language English
    Publishing date 1995-02
    Publishing country United States
    Document type Letter
    ZDB-ID 448469-1
    ISSN 1533-0311 ; 0193-1091
    ISSN (online) 1533-0311
    ISSN 0193-1091
    DOI 10.1097/00000372-199502000-00018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Giant congenital nevi: a conceptualization of patterns.

    Reed, R J

    The Journal of investigative dermatology

    1993  Volume 100, Issue 3, Page(s) 300S–312S

    Abstract: Patterns in giant congenital nevi are classified as to extent of cellular involvement of the reticular dermis and by the quality of the fibrous matrix. In addition, classifications are influenced by degrees of cellular atypia. Two general categories are ... ...

    Abstract Patterns in giant congenital nevi are classified as to extent of cellular involvement of the reticular dermis and by the quality of the fibrous matrix. In addition, classifications are influenced by degrees of cellular atypia. Two general categories are defined. In one, the phenomena are relatively independent of those operative at the dermal-epidermal interface. The lesions are characterized as dermal congenital tumorous dysplasias-blastomas. They are subdivided into major, intermediate, and minor categories and into mature and immature variants. In these variants, disparate populations in the patterns of nodules and plaques (lumpy-bumpy variants) qualify as dermal variants of minimal deviation melanoma as seen in the setting of giant congenital nevi. The respective melanomas in this category are small-cell malignant neoplasms (melanoblastomas of infancy and childhood). In a second category in the clinical setting of giant congenital nevus, rare childhood and some adult melanomas of a more common histologic type evolve from lentiginous and junctional components in patterns that recapitulate those of the dysplastic nevus syndrome. The suspicious areas in all categories are evaluated by the same clinical criteria. In the dysplasia-blastoma category, enlarging nodules must be biopsied. The criteria for the evaluation of lesions in the dysplastic nevus syndrome and in the category of minimal deviation melanoma have application to the unstable regions in giant congenital nevi.
    MeSH term(s) Humans ; Nevus/congenital ; Nevus/pathology
    Language English
    Publishing date 1993-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80136-7
    ISSN 1523-1747 ; 0022-202X
    ISSN (online) 1523-1747
    ISSN 0022-202X
    DOI 10.1111/1523-1747.ep12470191
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  7. Article: MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.

    SOBOTA, J T / REED, R J

    Diseases of the chest

    2003  Volume 46, Page(s) 367–371

    MeSH term(s) 17-Hydroxycorticosteroids ; 17-Ketosteroids ; Adenoma ; Adrenalectomy ; Adrenocorticotropic Hormone ; Alkalosis ; Bartter Syndrome ; Bronchial Neoplasms ; Cushing Syndrome ; Dexamethasone ; Heart Arrest ; Humans ; Hypokalemia ; Metyrapone ; Neoplasms/diagnosis ; Neoplasms, Multiple Primary ; Pathology ; Radiography, Thoracic ; Urine
    Chemical Substances 17-Hydroxycorticosteroids ; 17-Ketosteroids ; Dexamethasone (7S5I7G3JQL) ; Adrenocorticotropic Hormone (9002-60-2) ; Metyrapone (ZS9KD92H6V)
    Language English
    Publishing date 2003-08-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80096-x
    ISSN 1931-3543 ; 0096-0217
    ISSN (online) 1931-3543
    ISSN 0096-0217
    DOI 10.1378/chest.46.3.367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Minimal deviation melanoma.

    Reed, R J

    Human pathology

    1990  Volume 21, Issue 12, Page(s) 1206–1211

    MeSH term(s) Growth ; Humans ; Melanoma/pathology ; Melanoma/physiopathology ; Skin Neoplasms/pathology ; Skin Neoplasms/physiopathology ; Terminology as Topic
    Language English
    Publishing date 1990-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/s0046-8177(06)80032-8
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  9. Article: Basal cell carcinoma with follicular differentiation.

    Reed, R J

    The American Journal of dermatopathology

    1989  Volume 11, Issue 5, Page(s) 497–505

    MeSH term(s) Carcinoma, Basal Cell/pathology ; Cell Differentiation ; Humans ; Skin Neoplasms/pathology
    Language English
    Publishing date 1989-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 448469-1
    ISSN 1533-0311 ; 0193-1091
    ISSN (online) 1533-0311
    ISSN 0193-1091
    DOI 10.1097/00000372-198910000-00013
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  10. Article: Cotyledonoid leiomyoma of the uterus: report of a case.

    Roth, L M / Reed, R J

    International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

    2000  Volume 19, Issue 3, Page(s) 272–275

    Abstract: A 46-year-old woman presented with a pelvic mass. At the time of operation a large, exophytic, multinodular tumor extended into the peritoneal cavity and right broad ligament from a pedunculated attachment to the uterus in the region of the right cornu. ... ...

    Abstract A 46-year-old woman presented with a pelvic mass. At the time of operation a large, exophytic, multinodular tumor extended into the peritoneal cavity and right broad ligament from a pedunculated attachment to the uterus in the region of the right cornu. On external examination the lesion had the appearance of cotyledonoid dissecting leiomyoma. On microscopic examination bulbous processes were composed of benign smooth muscle arranged in interlacing fascicles or swirls; there was focal hydropic degeneration. Significant nuclear atypia, mitotic activity, and coagulative tumor necrosis were not encountered. No intravascular involvement was present. There was no demonstrable parent leiomyoma or intramural dissecting component, and thus the case differed from previously reported cases of both cotyledonoid dissecting leiomyoma and intramural dissecting leiomyoma. This tumor represents another variation in the group of benign uterine smooth muscle tumors with unusual growth patterns.
    MeSH term(s) Biopsy ; Endometrium/pathology ; Fallopian Tubes/surgery ; Female ; Humans ; Hysterectomy ; Leiomyoma/pathology ; Leiomyoma/surgery ; Middle Aged ; Muscle, Smooth/pathology ; Myometrium/pathology ; Omentum/pathology ; Ovariectomy ; Uterine Neoplasms/pathology ; Uterine Neoplasms/surgery ; Uterus/pathology
    Language English
    Publishing date 2000-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604859-6
    ISSN 1538-7151 ; 0277-1691
    ISSN (online) 1538-7151
    ISSN 0277-1691
    DOI 10.1097/00004347-200007000-00012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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