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Article ; Online: Durability of Viral Neutralization in Asymptomatic Coronavirus Disease 2019 for at Least 60 Days.

Haymond, Amanda / Damluji, Abdulla A / Narayanan, Aarthi / Mueller, Claudius / Reeder, Alex / Alem, Farhang / Maxwell, G Larry / Petricoin, Emanuel F / Liotta, Lance / deFilippi, Christopher R

The Journal of infectious diseases

2021  Volume 223, Issue 10, Page(s) 1677–1680

Abstract: A cohort consisting of asymptomatic healthcare workers donated temporal serum samples after infection with severe acute respiratory syndrome coronavirus 2. Analysis shows that all asymptomatic healthcare workers had neutralizing antibodies, that these ... ...

Abstract A cohort consisting of asymptomatic healthcare workers donated temporal serum samples after infection with severe acute respiratory syndrome coronavirus 2. Analysis shows that all asymptomatic healthcare workers had neutralizing antibodies, that these antibodies persist for ≥60 days, and that anti-spike receptor-binding domain immunoglobulin G levels were correspondingly durable over the same time period.
MeSH term(s) Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Asymptomatic Diseases ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19 Nucleic Acid Testing ; Cohort Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Health Personnel ; Humans ; Male ; Neutralization Tests ; SARS-CoV-2/immunology ; Surveys and Questionnaires ; Time Factors ; Virginia/epidemiology
Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral
Language English
Publishing date 2021-02-08
Publishing country United States
Document type Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID 3019-3
ISSN 1537-6613 ; 0022-1899
ISSN (online) 1537-6613
ISSN 0022-1899
DOI 10.1093/infdis/jiab140
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