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  1. Article ; Online: Multifaceted Applications of DNA-Capped Silver Nanoparticles in Photonics, Photocatalysis, Antibacterial Activity, Cytotoxicity, and Bioimaging.

    Reena, V N / Bhagyasree, G S / Shilpa, T / Aswati Nair, R / Nithyaja, B

    Journal of fluorescence

    2024  

    Abstract: Deoxyribonucleic acid (DNA) capped silver nanoparticles are exceptional nanomaterials, featuring precise size and shape control enabled by DNA as a capping agent. DNA stabilizes these nanoparticles' role leading to uniform structures for diverse ... ...

    Abstract Deoxyribonucleic acid (DNA) capped silver nanoparticles are exceptional nanomaterials, featuring precise size and shape control enabled by DNA as a capping agent. DNA stabilizes these nanoparticles' role leading to uniform structures for diverse applications. These nanoparticles are excellent in photonics and medical applications, enhancing fluorescence and medical imaging. In this study, we explore the multifaceted applications of DNA-capped silver nanoparticles, delving into their optical, photocatalytic, antibacterial, cytotoxic, and bioimaging properties. Employing UV-visible absorption spectroscopy and scanning electron microscopy, we provide an analysis of confirmation of silver nanoparticles. The investigation demonstrates substantial photocatalytic efficacy, photodegradation of methylene blue is higher than rhodamine 6G. The presence of silver nanoparticles enhances the fluorescence of rhodamine 6G doped sol-gel glasses. Furthermore, our findings illustrate significant antibacterial effects, encompassing both Gram-positive and Gram-negative bacteria, with DNA-capped silver nanoparticles exhibiting antibacterial activity. Cytotoxicity assessments on HeLa cells reveal concentration-dependent effects, with an LC
    Language English
    Publishing date 2024-02-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-023-03556-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Photocatalytic, Antibacterial, Cytotoxic and Bioimaging Applications of Fluorescent CdS Nanoparticles Prepared in DNA Biotemplate.

    Reena, V N / Bhagyasree, G S / Shilpa, T / Aswati Nair, R / Misha, H / Nithyaja, B

    Journal of fluorescence

    2023  Volume 34, Issue 1, Page(s) 437–448

    Abstract: Synthesizing nanoparticles in biotemplates has been cited as one of the most promising way to obtain monodispersed inorganic nanoparticles. In this method, uniform voids in porous materials serve as hosts to confine the synthesized nanoparticles. DNA ... ...

    Abstract Synthesizing nanoparticles in biotemplates has been cited as one of the most promising way to obtain monodispersed inorganic nanoparticles. In this method, uniform voids in porous materials serve as hosts to confine the synthesized nanoparticles. DNA template can be described as a smart glue for assembling nanoscale building blocks. Here we investigate the photocatalytic, antibacterial, cytotoxic, and bioimaging applications of DNA capped CdS. XRD, SEM, TEM, UV-visible absorption, and photoluminescence spectra were used to study structural, morphological, and optical properties of CdS nanoparticles. Prepared CdS nanoparticles exhibit visible fluorescence. The photocatalytic activity of CdS towards Rhodamine 6G and Methylene blue are 64% and 91% respectively. A disc-diffusion method is used to demonstrate antibacterial screening. It was shown that CdS nanoparticles inhibit Gram-positive bacteria and Gram-negative bacteria effectively. DNA capped CdS shows higher activity than uncapped CdS nanoparticles. MTT cell viability assays were carried out in HeLa cells to investigate the cytotoxicity for 24 h. At a concentration 2.5 µg/ml, it shows 84% cell viability and 43% viability at 12.5 µg/ml. The calculated LC
    MeSH term(s) Humans ; HeLa Cells ; Nanoparticles/chemistry ; Anti-Bacterial Agents/chemistry ; Coloring Agents ; DNA
    Chemical Substances Anti-Bacterial Agents ; Coloring Agents ; DNA (9007-49-2)
    Language English
    Publishing date 2023-06-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-023-03292-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Photocatalytic and Enhanced Biological Activities of Schiff Base Capped Fluorescent CdS Nanoparticles.

    Reena, V N / Kumar, K Subin / Shilpa, T / Aswati Nair, R / Bhagyasree, G S / Nithyaja, B

    Journal of fluorescence

    2023  Volume 33, Issue 5, Page(s) 1927–1940

    Abstract: In the present work, biocompatible CdS nanoparticles were synthesized using Schiff base ligand, 3-((2-(-(1-(2hydroxyphenyl)ethylidene)amino)ethyl)imino)-2-pentone, by a simple ultrasonic irradiation method. The structural, morphological, and optical ... ...

    Abstract In the present work, biocompatible CdS nanoparticles were synthesized using Schiff base ligand, 3-((2-(-(1-(2hydroxyphenyl)ethylidene)amino)ethyl)imino)-2-pentone, by a simple ultrasonic irradiation method. The structural, morphological, and optical properties were studied using XRD, SEM, TEM, UV-visible absorption, and photoluminescence (PL) spectra. The quantum confinement effect of the Schiff base capped CdS nanoparticles was confirmed by using UV-visible and PL spectrum analysis. This CdS nanoparticles were an effective photocatalyst for degrading rhodamine 6G and methylene blue with a 70% and 98% degradation capacity, respectively. Furthermore, the disc-diffusion method demonstrated that CdS nanoparticles inhibit G-positive bacteria and G-negative bacteria more effectively. These Schiff base capped CdS nanoparticles were taken for an in-vitro experiment with HeLa cells to exhibit the possibility of providing optical probes in biological applications and observed under a fluorescence microscope. In addition, MTT cell viability assays were carried out to investigate the cytotoxicity for 24 h. As a result of this study, 2.5 µg/ml doses of CdS nanoparticles are suitable for imaging and are effective in destroying HeLa cells. The present study suggests that the synthesized Schiff base capped CdS nanoparticles could be a potential photocatalyst, antibacterial agent, and biocompatible nanoparticle for bioimaging applications.
    MeSH term(s) Humans ; HeLa Cells ; Schiff Bases/pharmacology ; Nanoparticles/chemistry ; Spectrum Analysis ; Diagnostic Imaging
    Chemical Substances Schiff Bases
    Language English
    Publishing date 2023-03-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-023-03193-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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