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  1. Article: From Prehistory to Precision Medicine: Are Genetic Risk Scores Our Next Step?

    Reid, Sarah

    The Journal of rheumatology

    2021  Volume 48, Issue 6, Page(s) 799–801

    MeSH term(s) Humans ; Precision Medicine ; Risk Factors
    Language English
    Publishing date 2021-03-15
    Publishing country Canada
    Document type Editorial
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.201256
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1168: Show issues Location:
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    Zs.MO 135: Show issues

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  2. Article: Introduction: Data and the need to quantify: a personal perspective.

    Reid, S W J

    Revue scientifique et technique (International Office of Epizootics)

    2023  Volume 42, Page(s) 13–23

    Title translation Introduction: Data and the need to quantify: a personal perspective.
    Language Spanish
    Publishing date 2023-05-30
    Publishing country France
    Document type Journal Article
    ZDB-ID 792125-1
    ISSN 1608-0637 ; 0253-1933
    ISSN (online) 1608-0637
    ISSN 0253-1933
    DOI 10.20506/rst.42.3344
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    Zs.MO 291: Show issues

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  3. Article ; Online: Vaccine safety.

    Reid, Stewart

    The New Zealand medical journal

    2020  Volume 133, Issue 1510, Page(s) 83–87

    Abstract: The purpose of this article is to offer evidence that vaccine safety is taken very seriously and various examples to support this premise are described. The article covers adverse event reporting following vaccination, the difference between events which ...

    Abstract The purpose of this article is to offer evidence that vaccine safety is taken very seriously and various examples to support this premise are described. The article covers adverse event reporting following vaccination, the difference between events which occur after vaccination and events which are caused by vaccination, the comprehensive safety monitoring required when vaccines are first introduced, international vaccine withdrawals because of safety concerns and some vaccine changes in New Zealand where safety was an important consideration. Finally, recent developments in vaccine safety monitoring are outlined. It is hoped that this will be a useful resource for those involved in the complex issue of counteracting vaccine hesitancy.
    MeSH term(s) Health Policy ; Humans ; New Zealand ; Patient Safety/standards ; Product Surveillance, Postmarketing/methods ; Product Surveillance, Postmarketing/standards ; Vaccines/adverse effects
    Chemical Substances Vaccines
    Language English
    Publishing date 2020-02-21
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 390590-1
    ISSN 1175-8716 ; 0028-8446 ; 0110-7704
    ISSN (online) 1175-8716
    ISSN 0028-8446 ; 0110-7704
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  4. Article: Phenotypic Plasticity Drives Seasonal Thermal Tolerance in a Baltic Copepod.

    Hahn, Alexandra / Brennan, Reid S

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Seasonal changes in environmental conditions require substantial physiological responses for population persistence. Phenotypic plasticity is a common mechanism to tolerate these changes, but for organisms with short generation times rapid adaptation may ...

    Abstract Seasonal changes in environmental conditions require substantial physiological responses for population persistence. Phenotypic plasticity is a common mechanism to tolerate these changes, but for organisms with short generation times rapid adaptation may also be a contributing factor. Here, we aimed to disentangle the impacts of adaptation from phenotypic plasticity on thermal tolerance of the calanoid copepod
    Language English
    Publishing date 2023-08-02
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.07.31.551281
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  5. Article ; Online: Evidence of prezygotic isolation, but not assortative mating, between locally adapted populations of Fundulus heteroclitus across a salinity gradient.

    Brennan, Reid S / Whitehead, Andrew

    Journal of evolutionary biology

    2023  Volume 36, Issue 4, Page(s) 687–697

    Abstract: Selection along environmental gradients can drive reproductive isolation and speciation. Among fishes, salinity is a major factor limiting species distributions, and despite its importance in generating species diversity, speciation events between marine ...

    Abstract Selection along environmental gradients can drive reproductive isolation and speciation. Among fishes, salinity is a major factor limiting species distributions, and despite its importance in generating species diversity, speciation events between marine and freshwater are rare. Here, we tested for mechanisms of reproductive isolation between locally adapted freshwater and brackish water-native populations of killifish, Fundulus heteroclitus, from either side of a hybrid zone along a salinity gradient. There was evidence for pre-zygotic endogenous reproductive isolation with reduced fertilization success between crosses of freshwater-native males and brackish water-native females. Exogenous pre-zygotic isolation was also present where females had highest fertilization in their native salinity. We used a replicated mass spawning design to test for mate choice in both brackish and fresh water. After genotyping 187 parents and 2523 offspring at 2347 SNPs across the genome, 85% of offspring were successfully assign to their parents. However, no reinforcing mate choice was observed. These results therefore demonstrate emerging, yet limited, reproductive isolation and incipient speciation across a marine to freshwater salinity gradient and suggest that both endogenous and exogenous mechanisms, but not assortative mating, contribute to divergence.
    MeSH term(s) Animals ; Female ; Male ; Fundulidae/genetics ; Salinity ; Adaptation, Physiological ; Reproductive Isolation ; Fresh Water
    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1465318-7
    ISSN 1420-9101 ; 1010-061X
    ISSN (online) 1420-9101
    ISSN 1010-061X
    DOI 10.1111/jeb.14159
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  6. Article ; Online: Characterization of the Effects of Ligands on Bonding and σ-Aromaticity of Small Pt Nanoclusters.

    Reid, Samantha / Hernández, Heriberto

    The journal of physical chemistry. A

    2023  Volume 127, Issue 19, Page(s) 4237–4244

    Abstract: Nanoclusters, particularly gold nanoclusters, have attracted the attention of researchers due to their potential applications in the medicine and energy fields. Other noble-metal nanoclusters, including Pt, have also been studied, but in lesser detail. ... ...

    Abstract Nanoclusters, particularly gold nanoclusters, have attracted the attention of researchers due to their potential applications in the medicine and energy fields. Other noble-metal nanoclusters, including Pt, have also been studied, but in lesser detail. Pt is known for its excellent catalytic properties and is a promising candidate for applications in catalysis and biomedicine. In this study, we used density functional theory to elucidate the molecular and electronic structures of small phosphine-ligated Pt nanoclusters. This study is directed at identifying highly stable platinum clusters. Our results show that phosphine-ligated platinum nanoclusters with σ-aromaticity have high stability. In addition, we were able to predict the most stable clusters using an electron counting equation.
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c08614
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  7. Article ; Online: The rural determinants of health: using critical realism as a theoretical framework.

    Reid, Steve

    Rural and remote health

    2019  Volume 19, Issue 3, Page(s) 5184

    Abstract: Rural health needs to be based on robust theory that guides efforts in practice, teaching and research. This could make the sets of assumptions that are inevitably brought to bear on prioritization and decision-making more explicit. It has not yet been ... ...

    Abstract Rural health needs to be based on robust theory that guides efforts in practice, teaching and research. This could make the sets of assumptions that are inevitably brought to bear on prioritization and decision-making more explicit. It has not yet been described in theoretical terms because to insiders such as health practitioners it seems to be more of a practical endeavour than an academic one. The rural determinants of health, as a more specific expression of the social determinants of health, include issues of geography and topography in addition to the social, economic and political factors that result in the persistent disadvantage in health access and outcomes of rural populations. The philosophical approach of critical realism provides a theoretical framework that is inclusive of subjective, objective and abstract realities. Using a case study from South Africa to illustrate these notions, a conceptual model is proposed that displays the geographical and historical foundations of rural health alongside the political, economic, social and health system factors influencing patterns of disease and wellness in rural areas.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Patient Acceptance of Health Care/psychology ; Patient Acceptance of Health Care/statistics & numerical data ; Public Health Administration/statistics & numerical data ; Rural Health Services/organization & administration ; Rural Health Services/statistics & numerical data ; Rural Population/statistics & numerical data ; Social Determinants of Health ; South Africa ; Urban Population/statistics & numerical data
    Language English
    Publishing date 2019-08-28
    Publishing country Australia
    Document type Comparative Study ; Journal Article
    ZDB-ID 2105620-1
    ISSN 1445-6354 ; 1445-6354
    ISSN (online) 1445-6354
    ISSN 1445-6354
    DOI 10.22605/RRH5184
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  8. Article ; Online: A 'training of trainers' programme for operational research: increasing capacity remotely.

    Willemsen, Angela / Wolka, Eskinder / Assefa, Yibeltal / Reid, Simon

    Global health action

    2024  Volume 17, Issue 1, Page(s) 2297881

    Abstract: Background: Operational research (OR) is a process to improve health system capacity by evaluating interventions to improve health delivery and outcomes. The World Health Organization (WHO) Structured Operational Research Training Initiative (SORT-IT) ... ...

    Abstract Background: Operational research (OR) is a process to improve health system capacity by evaluating interventions to improve health delivery and outcomes. The World Health Organization (WHO) Structured Operational Research Training Initiative (SORT-IT) programme promotes how OR contributes to improved health care delivery and health outcomes. A partnership project between the International Institute of Primary Health Care (IPHCE) in Ethiopia and The University of Queensland (UQ) in Australia modified the SORT-IT programme to deliver a hybrid Training of Trainers programme and improve OR capacity.
    Objective: This study was performed to develop and evaluate the effectiveness of Train-the Trainers approach in building capability to expand the capacity of the IPHCE to deliver the SORT-IT programme.
    Methods: Recruitment of participants and training were aligned with the principles of the SORT-IT programme. Training was face-to-face for the first session with subsequent training sessions delivered via Zoom over a 13-week period. Participants were required to complete all activities in line with SORT-IT deliverables. Slide decks supporting the SORT-IT training videos were developed and adapted to the Ethiopian context.
    Results: Participants had diverse experience from programme directors to research officers. All training sessions were recorded and available for participants to watch and review when required. All participants completed OR protocols to the draft stage. Course evaluation revealed participants found the content and format of the training useful, pertinent, and interesting.
    Conclusion: A hybrid model (face-to-face and video platform) for OR training was implemented. Managing contextual challenges such as information technology were managed easily by programme staff. Translating course requirements at a management level proved challenging with data collection for the protocols but provided insight into potential future challenges. This OR Training of Trainers course demonstrated that sharing of skills and knowledge can occur through a hybrid delivery model and contribute to developing capacity.
    MeSH term(s) Humans ; Operations Research ; Delivery of Health Care ; Data Collection ; Ethiopia ; Australia ; Capacity Building/methods
    Language English
    Publishing date 2024-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2540569-X
    ISSN 1654-9880 ; 1654-9880
    ISSN (online) 1654-9880
    ISSN 1654-9880
    DOI 10.1080/16549716.2023.2297881
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  9. Article ; Online: Taking a value based commissioning approach to non-clinical and clinical support services.

    Kinsman, Trinette / Reid, Samantha / Arnott, Hayley

    Australian health review : a publication of the Australian Hospital Association

    2024  Volume 48

    Abstract: Value based healthcare beyond the clinical domain is the focus of this case study. We share NSW Health's experiences in achieving value through a focus on outcomes in non-clinical and clinical support services using examples that demonstrate key aspects ... ...

    Abstract Value based healthcare beyond the clinical domain is the focus of this case study. We share NSW Health's experiences in achieving value through a focus on outcomes in non-clinical and clinical support services using examples that demonstrate key aspects across the commissioning cycle. These include: the importance of stakeholder engagement in the planning phase to later success; the critical role of non-clinical services in patient experience; the opportunity to facilitate value by introducing new approaches in business areas such as procurement; and the role of clinical supports such as digital enablement to facilitate outcome-focussed clinical models. Applying a value lens to non-clinical services can increase the potential benefits to patients, clinicians and the system.
    MeSH term(s) Humans ; Delivery of Health Care ; Health Facilities ; State Medicine
    Language English
    Publishing date 2024-03-20
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 639155-2
    ISSN 1449-8944 ; 0159-5709 ; 0156-5788
    ISSN (online) 1449-8944
    ISSN 0159-5709 ; 0156-5788
    DOI 10.1071/AH23278
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    Zs.B 3099: Show issues Location:
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  10. Article ; Online: Can 'life writing' be therapeutic in response to trauma? An exploratory research project in Medical Humanities in South Africa.

    Garisch, Dawn / Giddy, Janet / Griffin, Giles / Reid, Steve

    Medical humanities

    2024  Volume 50, Issue 1, Page(s) 162–169

    Abstract: The therapeutic benefit of expressive writing has been well researched in the Global North but there is no literature from the Global South. Potentially healing interventions need to be investigated in different contexts, particularly where there is a ... ...

    Abstract The therapeutic benefit of expressive writing has been well researched in the Global North but there is no literature from the Global South. Potentially healing interventions need to be investigated in different contexts, particularly where there is a need to build social cohesion. South Africa has a violent past and is a highly stressed society. An exploration of self-reports by a diverse group of South Africans on the effects of life writing on their health and well-being was conducted using qualitative methods. Twenty members of a writing collective, the Life Righting Collective (LRC: www.liferighting.co.za), were purposively sampled and interviewed by medical students as part of a Medical Humanities special study module. Five major interconnected themes emerged. The LRC as a specific intervention was central to the benefits described. The findings of this study indicated that life writing is a useful non-medical, cost-efficient method to improve resilience to trauma, as well as improving the psychological well-being of the participants. In addition, participants reported positive experiences regarding personal development, overall wellness and mental health, and that life writing can engender a sense of community. Resource-constrained countries in the Global South, like South Africa, where there have been historical and ongoing multiple traumas, need interventions for healing and wellness that are low cost and can be replicated.
    MeSH term(s) Humans ; South Africa ; Humanities ; Research Design ; Mental Health ; Writing
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018219-3
    ISSN 1473-4265 ; 1468-215X
    ISSN (online) 1473-4265
    ISSN 1468-215X
    DOI 10.1136/medhum-2021-012368
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    Zs.A 5257: Show issues Location:
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