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  1. Book ; Thesis: Characterization of immune cell populations in a murine model of human trisomy 21

    Reimer, Katharina Charlotte

    2018  

    Author's details vorgelegt von Katharina Charlotte Reimer
    Language English
    Size 212 Seiten, Illustrationen, Diagramme, 21 cm
    Publishing place Erlangen ; Nürnberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Alexander-Universität Erlangen-Nürnberg, 2018
    HBZ-ID HT020165563
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 D 823 order for loan Magazin

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  2. Article ; Online: Protocol to analyze bioenergetics in single human induced-pluripotent-stem-cell-derived kidney organoids using Seahorse XF96.

    Miguel, Verónica / Reimer, Katharina Charlotte / Galyga, Anna Katharina / Jansen, Jitske / Möllmann, Julia / Meyer, Luisa / Schneider, Rebekka K / Kramann, Rafael

    STAR protocols

    2023  Volume 4, Issue 1, Page(s) 101999

    Abstract: Metabolic derangement is a key culprit in kidney pathophysiology. Organoids have emerged as a promising in vitro tool for kidney research. Here, we present a fine-tuned protocol to analyze bioenergetics in single human induced-pluripotent-stem-cell (iPSC) ...

    Abstract Metabolic derangement is a key culprit in kidney pathophysiology. Organoids have emerged as a promising in vitro tool for kidney research. Here, we present a fine-tuned protocol to analyze bioenergetics in single human induced-pluripotent-stem-cell (iPSC)-derived kidney organoids using Seahorse XF96. We describe the generation of self-organized three-dimensional kidney organoids, followed by preparation of organoids for Seahorse XF96 analysis. We then detail how to carry out stress tests to determine mitochondrial and glycolytic rates in single kidney organoids.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells ; Solitary Kidney/metabolism ; Cell Differentiation ; Kidney ; Organoids ; Energy Metabolism
    Language English
    Publishing date 2023-01-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2666-1667
    ISSN (online) 2666-1667
    DOI 10.1016/j.xpro.2022.101999
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort.

    Reimer, Katharina Charlotte / Nadal, Jennifer / Meiselbach, Heike / Schmid, Matthias / Schultheiss, Ulla T / Kotsis, Fruzsina / Stockmann, Helena / Friedrich, Nele / Nauck, Matthias / Krane, Vera / Eckardt, Kai-Uwe / Schneider, Markus P / Kramann, Rafael / Floege, Jürgen / Saritas, Turgay

    Bone research

    2023  Volume 11, Issue 1, Page(s) 52

    Abstract: Mineral and bone disorder (MBD) in chronic kidney disease (CKD) is tightly linked to cardiovascular disease (CVD). In this study, we aimed to compare the prognostic value of nine MBD biomarkers to determine those associated best with adverse ... ...

    Abstract Mineral and bone disorder (MBD) in chronic kidney disease (CKD) is tightly linked to cardiovascular disease (CVD). In this study, we aimed to compare the prognostic value of nine MBD biomarkers to determine those associated best with adverse cardiovascular (CV) outcomes and mortality. In 5 217 participants of the German CKD (GCKD) study enrolled with an estimated glomerular filtration rate (eGFR) between 30-60 mL·min
    MeSH term(s) Humans ; Renal Insufficiency, Chronic ; Minerals ; Parathyroid Hormone ; Vitamin D ; Biomarkers
    Chemical Substances Minerals ; Parathyroid Hormone ; Vitamin D (1406-16-2) ; Biomarkers
    Language English
    Publishing date 2023-10-20
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2803313-9
    ISSN 2095-6231 ; 2095-4700
    ISSN (online) 2095-6231
    ISSN 2095-4700
    DOI 10.1038/s41413-023-00291-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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