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Article ; Online: Knowledge of SARS-CoV-2 antigen detection and proper use of rapid diagnostic self-test among Shanghai residents in China.

Gu, Ren-Ping / Zhu, Ai-Yong

2023 Volume 11, Page(s) 1036823

Abstract: Objectives: To assess and evaluate the knowledge of Shanghai, China, residents on the use of SARS-CoV-2 antigen detection and rapid diagnostic self-test.: Methods: A cross-sectional electronic survey using a self-administered questionnaire was sent !# ...

Abstract	Objectives: To assess and evaluate the knowledge of Shanghai, China, residents on the use of SARS-CoV-2 antigen detection and rapid diagnostic self-test. Methods: A cross-sectional electronic survey using a self-administered questionnaire was sent Results: A total of 283 participants were recruited between July 1, 2022 and July 20, 2022 through an online survey. The mean score of knowledge on the tests was 14.33 ± 2.85 (out of 21). The questions concerning the depth of swab insertion and minimum number of swab rotations in the nostril, necessity of bilateral sampling, necessity of rotating and squeezing the swab for 10 times in the extraction buffer tube, and waiting time for the results showed the highest rate of incorrect responses. In the multiple regression analysis model, sex, social status, and source of information were associated with the knowledge on the self-test kits. Conclusion: Immediate health education programs should be made available and the kits could be improved appropriately to ensure adequate knowledge. The use of technology should be fully leveraged to achieve accurate self-diagnosis and correct interpretation of the results.
MeSH term(s)	Humans ; SARS-CoV-2 ; COVID-19/diagnosis ; Rapid Diagnostic Tests ; Cross-Sectional Studies ; Self-Testing ; China ; COVID-19 Testing
Language	English
Publishing date	2023-01-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1036823
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Is teacher preference associated with aggressive behavior among Chinese adolescents: The mediating role of peer rejection and rejection sensitivity.

Yang, Liu / Gao, Ting / Xiong, Yuke / Ren, Ping

Aggressive behavior

2023 Volume 49, Issue 6, Page(s) 687–700

Abstract: Few studies have explored the potential impact of teacher preferences on students' peer relationships and their broader psycho-behavioral growth from the perspective of classroom peer ecology. To remedy this research gap, this study hypothesized and ... ...

Abstract	Few studies have explored the potential impact of teacher preferences on students' peer relationships and their broader psycho-behavioral growth from the perspective of classroom peer ecology. To remedy this research gap, this study hypothesized and tested a serial mediation model in which teacher preference is related to adolescents' aggressive behavior via the indirect paths of forming peer rejection and shaping rejection sensitivity. Using a longitudinal design, two-wave data were obtained from 2270 Chinese adolescents (initial age = 13.93 ± 0.59, 50.7% boys) over 6 months. The results revealed that teacher preference was negatively associated with aggressive behavior in adolescents, and the mediation model indicated peer rejection and rejection sensitivity served as serial mediators between this link. Additionally, the current study examined the unique affiliations of anxiety and anger about rejection with aggressive behavior respectively, with results supporting them as distinct constructs and highlighting the significance of research integrating both forms of rejection sensitivity. Differences were also identified regarding the role of anxious rejection sensitivity in predicting proactive and reactive aggressive behaviors. The educational implications of these findings and directions for forthcoming research were discussed.
Language	English
Publishing date	2023-07-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	189812-7
ISSN	1098-2337 ; 0096-140X
ISSN (online)	1098-2337
ISSN	0096-140X
DOI	10.1002/ab.22107
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Article ; Online: SARS-CoV-2 serology testing: Progress and challenges.

Shi, Aria C / Ren, Ping

Journal of immunological methods

2021 Volume 494, Page(s) 113060

Abstract: The coronavirus disease 2019 (COVID-19) pandemic has caused the most devasting social and economic impact of this century. The current pandemic will end only after a safe, effective vaccine becomes available and protective herd immunity has been achieved ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic has caused the most devasting social and economic impact of this century. The current pandemic will end only after a safe, effective vaccine becomes available and protective herd immunity has been achieved through vaccination. The key parameter to gauge protective immunity is neutralizing antibody levels. Thus, reliable serology testing is essential to diagnose whether an individual has been previously infected, as a large proportion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is asymptomatic. For both naturally infected and vaccinated individuals, it is critical to monitor their neutralizing antibody titers over time. This is because, when neutralizing antibody levels wane below a threshold which remains to be determined, they become vulnerable to reinfection. Due to the importance of serology testing, academia and industry have developed different platforms for serological diagnosis, many of which have achieved the Food and Drug Administration (FDA) Emergency Use Authorizations (EUA). Here we summarize the status of COVID-19 serology testing, discuss challenges, and provide future directions for improvement.
MeSH term(s)	Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19 Serological Testing ; Humans ; SARS-CoV-2/metabolism
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral
Language	English
Publishing date	2021-04-26
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	120142-6
ISSN	1872-7905 ; 0022-1759
ISSN (online)	1872-7905
ISSN	0022-1759
DOI	10.1016/j.jim.2021.113060
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Article ; Online: Identification of therapeutic targets and prognostic biomarkers in the Siglec family of genes in tumor immune microenvironment of sarcoma.

Qi, Lili / Jiang, Kuiying / Zhao, Fei-Fei / Ren, Ping / Wang, Ling

Scientific reports

2024 Volume 14, Issue 1, Page(s) 577

Abstract: Sarcomas (SARC) are a highly heterogeneous cancer type that is prone to recurrence and metastasis. Numerous studies have confirmed that Siglecs are involved in immune signaling and play a key role in regulating immune responses in inflammatory diseases ... ...

Abstract	Sarcomas (SARC) are a highly heterogeneous cancer type that is prone to recurrence and metastasis. Numerous studies have confirmed that Siglecs are involved in immune signaling and play a key role in regulating immune responses in inflammatory diseases and various cancers. However, studies that systematically explore the therapeutic and prognostic value of Siglecs in SARC patients are very limited. The online databases GEPIA, UALCAN, TIMER, The Kaplan-Meier Plotter, GeneMANIA, cBioPortal, and STING were used in this study. IHC staining was performed on the collected patient tissues, and clinical data were statistically analyzed. The transcript levels of most Siglec family members showed a high expression pattern in SARC. Compared with normal tissues, Siglec-5, Siglec-10, and Siglec-12 were abnormally highly expressed in tumor tissues. Importantly, Siglec-15 was significantly associated with poor prognosis. Functional enrichment analysis showed that the Siglec family was mainly enriched in hematopoietic cell lineages. The genes associated with molecular mutations in the Siglec family were mainly TP53 and MUC16, among which Siglec-2 and Siglec-15 were significantly associated with the survival of patients. The expression levels of all Siglec family members were significantly correlated with various types of immune cells (B cells, CD8 + T cells, CD4 + T cells, macrophages, neutrophils and dendritic cells). Furthermore, a significant correlation was found between the somatic copy number changes of all Siglec molecules and the abundance of immune infiltrates. Our study paints a promising vision for the development of immunotherapy drugs and the construction of prognostic stratification models by investigating the therapeutic and prognostic potential of the Siglec family for SARC.
MeSH term(s)	Humans ; Sialic Acid Binding Immunoglobulin-like Lectins/genetics ; Prognosis ; Sarcoma/genetics ; Soft Tissue Neoplasms ; Biomarkers ; Tumor Microenvironment/genetics
Chemical Substances	Sialic Acid Binding Immunoglobulin-like Lectins ; Biomarkers
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-50758-1
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Article ; Online: In Situ Construction of a Hydrophobic Honeycomb-like Structured ZnMoO

Dai, Wenjing / Yun, Hong / Lyu, Miaoqiang / Chen, Yuyao / Ren, Ping / Wang, Baofeng / Xu, Qunjie

Langmuir : the ACS journal of surfaces and colloids

2024 Volume 40, Issue 17, Page(s) 9028–9038

Abstract: Aqueous zinc-ion batteries (AZIBs) suffer from sharp cycling deterioration due to serious interfacial side reactions and corrosion problems on the zinc anode. Herein, an efficacious approach to construct hydrophobic ... ...

Abstract	Aqueous zinc-ion batteries (AZIBs) suffer from sharp cycling deterioration due to serious interfacial side reactions and corrosion problems on the zinc anode. Herein, an efficacious approach to construct hydrophobic ZnMoO
Language	English
Publishing date	2024-04-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.4c00354
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Article: SARS-CoV-2 serology testing: Progress and challenges

Shi, Aria C / Ren, Ping

Journal of immunological methods. 2021 July, v. 494

2021

Abstract	The coronavirus disease 2019 (COVID-19) pandemic has caused the most devasting social and economic impact of this century. The current pandemic will end only after a safe, effective vaccine becomes available and protective herd immunity has been achieved through vaccination. The key parameter to gauge protective immunity is neutralizing antibody levels. Thus, reliable serology testing is essential to diagnose whether an individual has been previously infected, as a large proportion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is asymptomatic. For both naturally infected and vaccinated individuals, it is critical to monitor their neutralizing antibody titers over time. This is because, when neutralizing antibody levels wane below a threshold which remains to be determined, they become vulnerable to reinfection. Due to the importance of serology testing, academia and industry have developed different platforms for serological diagnosis, many of which have achieved the Food and Drug Administration (FDA) Emergency Use Authorizations (EUA). Here we summarize the status of COVID-19 serology testing, discuss challenges, and provide future directions for improvement.
Keywords	COVID-19 infection ; Food and Drug Administration ; Severe acute respiratory syndrome coronavirus 2 ; economic impact ; herd immunity ; industry ; pandemic ; serodiagnosis ; serology ; vaccination ; vaccines
Language	English
Dates of publication	2021-07
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	120142-6
ISSN	1872-7905 ; 0022-1759
ISSN (online)	1872-7905
ISSN	0022-1759
DOI	10.1016/j.jim.2021.113060
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 795: Show issues

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Article ; Online: A person-centered approach to resilience against bullying victimization in adolescence: Predictions from teacher support and peer support.

Yang, Liu / Xiong, Yuke / Gao, Ting / Li, Simeng / Ren, Ping

Journal of affective disorders

2023 Volume 341, Page(s) 154–161

Abstract: Background: There is ample evidence that bullying victimization typically has deleterious effects on the developmental outcomes of adolescents, while little research attention has been paid to those who show "resilient" despite the stress associated ... ...

Abstract	Background: There is ample evidence that bullying victimization typically has deleterious effects on the developmental outcomes of adolescents, while little research attention has been paid to those who show "resilient" despite the stress associated with being bullied. This study aimed to identify such a group according to the severity of exposure to bullying victimization and psychological adaptation in terms of negative (i.e., depressive symptoms) as well as positive (i.e., subjective well-being) aspects, and to examine their associations with interpersonal sources in school ecology (i.e., teacher support and peer support) using a short-term longitudinal design. Methods: Latent profile analysis was performed on a sample of 2339 adolescents in junior high schools (M Results: The presence of a resilient (8.0 %) profile was identified, along with three other distinct profiles: normative (59.2 %), vulnerable (29.0 %), and adverse (3.8 %). Despite experiencing bullying victimization of comparable severity, adolescents who reported more teacher support and peer support were more likely to classify to the "Resilient" profile. Limitations: A broader range of malleable resource factors should be considered to enhance a nuanced understanding of what resource factors contribute to resilience. Multiple reporting sources should be applied to overcome information bias. And the results need to be verified across different cultural contexts, age groups, and regions. Conclusions: These findings add a new contribution to the literature by highlighting the utility of a person-centered approach in the field of victimization resilience studies and the important roles of teacher and peer support against bullying victimization. Future prevention and early intervention could consider support from teachers and peers as potentially robust and malleable targets.
MeSH term(s)	Male ; Humans ; Adolescent ; Child ; Female ; Bullying ; Peer Group ; Salaries and Fringe Benefits ; Schools
Language	English
Publishing date	2023-08-24
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2023.08.089
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Zs.A 1485: Show issues

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Article ; Online: Does Being Prosocial Pay Off? Testing Positive Developmental Cascades of Prosocial Behavior, Social Preference, and Subjective Well-Being in Chinese Adolescents.

Xiong, Yuke / Chen, Jiahui / Yang, Liu / Guo, Xiaolin / Ren, Ping

Journal of youth and adolescence

2023 Volume 52, Issue 9, Page(s) 1983–1994

Abstract: Positive aspects of adolescent development recently have raised researchers' interests; however, studies examining reciprocal links between prosocial behavior, social preference, and subjective well-being are lacking. The present longitudinal study ... ...

Abstract	Positive aspects of adolescent development recently have raised researchers' interests; however, studies examining reciprocal links between prosocial behavior, social preference, and subjective well-being are lacking. The present longitudinal study investigated the bidirectional relations between prosocial behavior, social preference, and subjective well-being within a theoretical framework of the developmental cascade model. A total of 1248 Chinese adolescents (M = 13.44, SD = 0.65; 47.0% girls) were surveyed across three waves with 6-month intervals. The results of analyses utilizing the random-intercept cross-lagged panel model demonstrated that prosocial behavior was positively associated with both social preference and subjective well-being, and social preference was not associated with subjective well-being at the between-person level. At the within-person level, prosocial behavior was positively reciprocally associated with social preference, while no significant relations between prosocial behavior and subjective well-being and between social preference and subjective well-being were found. The findings highlight adolescents' prosocial behavior and social preference could mutually facilitate each other over time, which can be used to guide adolescents' positive development.
MeSH term(s)	Female ; Humans ; Adolescent ; Male ; Social Behavior ; Altruism ; Longitudinal Studies ; East Asian People ; Adolescent Behavior
Language	English
Publishing date	2023-06-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	186743-x
ISSN	1573-6601 ; 0047-2891
ISSN (online)	1573-6601
ISSN	0047-2891
DOI	10.1007/s10964-023-01809-3
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Zs.B 3120: Show issues

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Article ; Online: Profiles and Transitions of Non-Suicidal Self-Injury and Depressive Symptoms among Adolescent Boys and Girls: Predictive Role of Bullying Victimization.

Liang, Yiting / Chen, Jiahui / Xiong, Yuke / Wang, Quanquan / Ren, Ping

Journal of youth and adolescence

2023 Volume 52, Issue 8, Page(s) 1705–1720

Abstract: Although non-suicidal self-injury (NSSI) and depressive symptoms often co-occur, as well as display distinct profiles in different genders, few studies examined the gender-specific profiles and transitions of NSSI and depressive symptoms among ... ...

Abstract	Although non-suicidal self-injury (NSSI) and depressive symptoms often co-occur, as well as display distinct profiles in different genders, few studies examined the gender-specific profiles and transitions of NSSI and depressive symptoms among adolescents and the role of bullying victimization on their profiles and transitions. This study examined the profiles and transitions of NSSI and depressive symptoms for Chinese adolescent boys and girls separately, along with the predictive role of bullying victimization in subgroup memberships and transitions. A total of 3510 adolescents (52.9% boy, M age = 13.36, SD = 0.50) participated in two waves of the study over six months. The results indicated that four and three profiles identified for girls and boys separately. Adolescents in at-risk profiles showed varying degrees of transition. Adolescents with more bullying victimization were more likely to belong or transition to at-risk profiles for both genders, and bullying victimization exacerbated girls transitioning into co-occurring high profile but not in boys. The findings indicate distinct profile and transition patterns of NSSI and depressive symptoms, as well as different risk role of bullying victimization on their profiles and transitions in boys and girls, highlighting the importance of gender differences in understanding co-occurring and transitional nature of NSSI and depressive symptoms and the risk role of bullying victimization, informing effective strategies for prevention and intervention.
MeSH term(s)	Humans ; Male ; Adolescent ; Female ; Depression/epidemiology ; Self-Injurious Behavior/epidemiology ; Bullying ; Crime Victims ; Sex Factors
Language	English
Publishing date	2023-05-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	186743-x
ISSN	1573-6601 ; 0047-2891
ISSN (online)	1573-6601
ISSN	0047-2891
DOI	10.1007/s10964-023-01779-6
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Zs.B 3120: Show issues

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Article ; Online: Doubly Constrained Waveform Optimization for Integrated Sensing and Communications.

Ni, Zhitong / Zhang, Andrew Jian / Liu, Ren-Ping / Yang, Kai

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 13

Abstract: This paper investigates threshold-constrained joint waveform optimization for an integrated sensing and communication (ISAC) system. Unlike existing studies, we employ mutual information (MI) and sum rate (SR) as sensing and communication metrics, ... ...

Abstract	This paper investigates threshold-constrained joint waveform optimization for an integrated sensing and communication (ISAC) system. Unlike existing studies, we employ mutual information (MI) and sum rate (SR) as sensing and communication metrics, respectively, and optimize the waveform under constraints to both metrics simultaneously. This provides significant flexibility in meeting system performance. We formulate three different optimization problems that constrain the radar performance only, the communication performance only, and the ISAC performance, respectively. New techniques are developed to solve the original problems, which are NP-hard and cannot be directly solved by conventional semi-definite programming (SDP) techniques. Novel gradient descent methods are developed to solve the first two problems. For the third non-convex optimization problem, we transform it into a convex problem and solve it via convex toolboxes. We also disclose the connections between three optimizations using numerical results. Finally, simulation results are provided and validate the proposed optimization solutions.
MeSH term(s)	Algorithms ; Computer Simulation
Language	English
Publishing date	2023-06-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23135988
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