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  1. Article: Investigating the Experiences of Online Instructors while engaging and empowering non-traditional learners in eCampus.

    Ren, Xinyue

    Education and information technologies

    2022  Volume 28, Issue 1, Page(s) 237–253

    Abstract: The purpose of the qualitative study was to investigate instructors' experiences of engaging non-traditional learners in eCampus. Online education was rapidly growing in many higher education institutions, especially during the pandemic. However, a high ... ...

    Abstract The purpose of the qualitative study was to investigate instructors' experiences of engaging non-traditional learners in eCampus. Online education was rapidly growing in many higher education institutions, especially during the pandemic. However, a high attrition rate could negatively impact student success. Research findings showed that engagement was a significant factor to increase students' online retention. Due to the flexibility and accessibility of online education, there was a high demand among non-traditional learners. However, limited research has been conducted to explore instructors' experiences while engaging non-traditional learners in eCampus. In the general qualitative study, twelve online instructors were recruited, and interviews and document analysis were used to collect data. The findings showed that instructors faced both challenges and opportunities while increasing engagement among non-traditional learners in online programs. These indicated the need for the diversity of course design, relationship and community building, the flexibility of engagement criteria, and the unpredictability of emotional engagement. Institutional support and resources were recommended to improve the future teaching practices and the success of online learners with underrepresented backgrounds.
    Language English
    Publishing date 2022-06-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2001930-0
    ISSN 1573-7608 ; 1360-2357
    ISSN (online) 1573-7608
    ISSN 1360-2357
    DOI 10.1007/s10639-022-11153-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cancer immunology and immunotherapy.

    Ren, Xiubao

    Cancer biology & medicine

    2022  Volume 18, Issue 4

    MeSH term(s) Humans ; Immunologic Factors ; Immunotherapy ; Neoplasms/therapy
    Chemical Substances Immunologic Factors
    Language English
    Publishing date 2022-08-12
    Publishing country China
    Document type Editorial
    ZDB-ID 2676322-9
    ISSN 2095-3941
    ISSN 2095-3941
    DOI 10.20892/j.issn.2095-3941.2021.0036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Transport pathway of the Ag

    Ren, Xiaoyu / Jin, Yongli

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25299

    Abstract: Artificial precipitation enhancement (APE) activities have been applied extensively around the world to enhance water resources. However, the transport way of the silver iodide catalyst utilized remains completely unknown. To address this issue, in this ... ...

    Abstract Artificial precipitation enhancement (APE) activities have been applied extensively around the world to enhance water resources. However, the transport way of the silver iodide catalyst utilized remains completely unknown. To address this issue, in this study, we monitored the content of silver ions (Ag
    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Posterior fossa transient ischemic attack in the setting of bilateral persistent hypoglossal arteries: A case report and literature review.

    Ren, Xiaolu

    Medicine

    2021  Volume 100, Issue 45, Page(s) e27875

    Abstract: Rationale: Persistent hypoglossal artery (PHA) is the second rare abnormal anastomosis of the internal carotid and vertebrobasilar arteries, and bilateral persistent hypoglossal arteries in particular have rarely been reported. This is the first case of ...

    Abstract Rationale: Persistent hypoglossal artery (PHA) is the second rare abnormal anastomosis of the internal carotid and vertebrobasilar arteries, and bilateral persistent hypoglossal arteries in particular have rarely been reported. This is the first case of bilateral persistent hypoglossal arteries presenting with posterior fossa transient ischemic attack (TIA).
    Patient concerns: We reported a 54-year old female with posterior fossa TIA due to the coexisting bilateral persistent hypoglossal arteries and left internal carotid artery stenosis.
    Diagnosis: The patient was diagnosed with posterior fossa TIA, bilateral persistent hypoglossal arteries and left internal carotid artery stenosis.
    Interventions: The patient was given aspirin 100 mg/qd and advised to avoid excessive neck movement.
    Outcomes: Symptoms of intermittent subjective dizziness accompanied by nausea were relieved.
    Lessons: Although requires no special treatment, PHA could be accompanied by hypoplasia of vertebral arteries and posterior communicating arteries and becomes the main blood supply pathway for the posterior circulation. Accurate identification and evaluation of PHA is important of ensuring the safety of carotid interventions and identifying specific types of stroke.
    MeSH term(s) Carotid Arteries ; Carotid Artery, Internal ; Carotid Stenosis/complications ; Female ; Humans ; Ischemic Attack, Transient/etiology ; Middle Aged ; Vertebral Artery/diagnostic imaging
    Language English
    Publishing date 2021-11-03
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000027875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Lung Progenitor and Stem Cell Transplantation as a Potential Regenerative Therapy for Lung Diseases.

    Serna Villa, Vanessa / Ren, Xi

    Transplantation

    2024  

    Abstract: Chronic lung diseases are debilitating illnesses ranking among the top causes of death globally. Currently, clinically available therapeutic options capable of curing chronic lung diseases are limited to lung transplantation, which is hindered by donor ... ...

    Abstract Chronic lung diseases are debilitating illnesses ranking among the top causes of death globally. Currently, clinically available therapeutic options capable of curing chronic lung diseases are limited to lung transplantation, which is hindered by donor organ shortage. This highlights the urgent need for alternative strategies to repair damaged lung tissues. Stem cell transplantation has emerged as a promising avenue for regenerative treatment of the lung, which involves delivery of healthy lung epithelial progenitor cells that subsequently engraft in the injured tissue and further differentiate to reconstitute the functional respiratory epithelium. These transplanted progenitor cells possess the remarkable ability to self-renew, thereby offering the potential for sustained long-term treatment effects. Notably, the transplantation of basal cells, the airway stem cells, holds the promise for rehabilitating airway injuries resulting from environmental factors or genetic conditions such as cystic fibrosis. Similarly, for diseases affecting the alveoli, alveolar type II cells have garnered interest as a viable alveolar stem cell source for restoring the lung parenchyma from genetic or environmentally induced dysfunctions. Expanding upon these advancements, the use of induced pluripotent stem cells to derive lung progenitor cells for transplantation offers advantages such as scalability and patient specificity. In this review, we comprehensively explore the progress made in lung stem cell transplantation, providing insights into the current state of the field and its future prospects.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 509: Show issues

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  6. Article: Autoethnographic Research to Explore Instructional Design Practices for Distance Teaching and Learning in a Cross-Cultural Context.

    Ren, Xinyue

    TechTrends : for leaders in education & training

    2021  Volume 66, Issue 1, Page(s) 47–55

    Abstract: The purpose of this autoethnography is to share my perspective of course design and delivery considerations based on my professional experience as an instructional designer for a virtual international exchange program during the COVID-19 pandemic. Due to ...

    Abstract The purpose of this autoethnography is to share my perspective of course design and delivery considerations based on my professional experience as an instructional designer for a virtual international exchange program during the COVID-19 pandemic. Due to the impact of the global pandemic, the partner institutions decided to take advantage of distance education to continue their exchange program. I was the instructional designer to support faculty's transition to online instruction. Little research has been conducted to explore instructional design practices for distance teaching and learning in an intercultural context. Therefore, I applied an individual autoethnography to collect and analyze data from my narratives and artifacts to understand my perspective of instructional design and delivery practices within a cross-cultural distance learning environment. The findings showed course design in transnational distance contexts was more complicated than in distance education in a single cultural context. My role as an instructional designer was influenced by factors at both micro and macro levels.
    Language English
    Publishing date 2021-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144706-8
    ISSN 1559-7075 ; 8756-3894
    ISSN (online) 1559-7075
    ISSN 8756-3894
    DOI 10.1007/s11528-021-00683-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Potential Endotype Transition for Coronavirus Disease 2019-Related Sepsis With Longitudinal Transcriptome Profiling.

    Ren, Xinyong

    Critical care medicine

    2021  Volume 49, Issue 7, Page(s) e719–e720

    MeSH term(s) COVID-19 ; Gene Expression Profiling ; Humans ; SARS-CoV-2 ; Sepsis/genetics
    Language English
    Publishing date 2021-08-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Microstructure reconstruction of 2D/3D random materials via diffusion-based deep generative models.

    Lyu, Xianrui / Ren, Xiaodan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5041

    Abstract: Microstructure reconstruction serves as a crucial foundation for establishing process-structure-property (PSP) relationship in material design. Confronting the limitations of variational autoencoder and generative adversarial network within generative ... ...

    Abstract Microstructure reconstruction serves as a crucial foundation for establishing process-structure-property (PSP) relationship in material design. Confronting the limitations of variational autoencoder and generative adversarial network within generative models, this study adopted the denoising diffusion probabilistic model (DDPM) to learn the probability distribution of high-dimensional raw data and successfully reconstructed the microstructures of various composite materials, such as inclusion materials, spinodal decomposition materials, chessboard materials, fractal noise materials, and so on. The quality of generated microstructure was evaluated using quantitative measures like spatial correlation functions and Fourier descriptor. On this basis, this study also achieved the regulation of microstructure randomness and the generation of gradient materials through continuous interpolation in latent space using denoising diffusion implicit model (DDIM). Furthermore, the two-dimensional microstructure reconstruction was extended to three-dimensional framework and integrated permeability as a feature encoding embedding. This enables the conditional generation of three-dimensional microstructures for random porous materials within a defined permeability range. The permeabilities of these generated microstructures were further validated through the application of the lattice Boltzmann method. The above methods provide new ideas and references for material reverse design.
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-54861-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: C3AR1 is a regulatory factor associated with coagulation cascade and inflammation in sepsis.

    Ren, Xuanrong / Fu, Qinghui

    Medicine

    2024  Volume 103, Issue 11, Page(s) e37519

    Abstract: Sepsis is a leading cause of mortality in intensive care units. Sepsis is associated with activation of the coagulation cascade and inflammation. The aim of this study was to identify coagulation-related genes in sepsis that may provide translational ... ...

    Abstract Sepsis is a leading cause of mortality in intensive care units. Sepsis is associated with activation of the coagulation cascade and inflammation. The aim of this study was to identify coagulation-related genes in sepsis that may provide translational potential therapeutic targets. The datasets GSE28750, GSE95233, and GSE65682 were downloaded from the gene expression omnibus database. Consensus-weighted gene co-expression network analysis (WGCNA) was used to identify sepsis modules. Gene set enrichment analysis was used to identify genes enriched in the coagulation cascade. The value of hub-gene in immunological analysis was tested in the validation sets (GSE95233). The value of hub-gene in clinical prognosis was tested in the validation sets (GSE65582). One thousand one hundred seventy-six genes with high connectivity in the clinically significant module were identified as hub genes. Ten genes were found to be enriched in coagulation-related signaling pathways. C3AR1 was selected for further analysis. The immune infiltration analysis showed that lower expression of C3AR1 was associated with immune response in sepsis and could be an independent predictor of survival status in sepsis patients. Meanwhile, univariate and multivariate Cox analysis showed that C3AR1 had a significant correlation with survival. C3AR1 may become an effective biomarker for worse outcomes in sepsis patients associated with immune and coagulation cascade.
    MeSH term(s) Humans ; Inflammation/genetics ; Sepsis/genetics ; Blood Coagulation/genetics ; Consensus ; Databases, Factual ; Gene Expression Profiling ; Gene Regulatory Networks
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
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  10. Article ; Online: Immunotherapy and drug sensitivity predictive roles of a novel prognostic model in hepatocellular carcinoma.

    Gao, Xiaoge / Ren, Xin / Wang, Feitong / Ren, Xinxin / Liu, Mengchen / Cui, Guozhen / Liu, Xiangye

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9509

    Abstract: Hepatocellular carcinoma (HCC) is one of the most significant causes of cancer-related deaths in the worldwide. Currently, predicting the survival of patients with HCC and developing treatment drugs still remain a significant challenge. In this study, we ...

    Abstract Hepatocellular carcinoma (HCC) is one of the most significant causes of cancer-related deaths in the worldwide. Currently, predicting the survival of patients with HCC and developing treatment drugs still remain a significant challenge. In this study, we employed prognosis-related genes to develop and externally validate a predictive risk model. Furthermore, the correlation between signaling pathways, immune cell infiltration, immunotherapy response, drug sensitivity, and risk score was investigated using different algorithm platforms in HCC. Our results showed that 11 differentially expressed genes including UBE2C, PTTG1, TOP2A, SPP1, FCN3, SLC22A1, ADH4, CYP2C8, SLC10A1, F9, and FBP1 were identified as being related to prognosis, which were integrated to construct a prediction model. Our model could accurately predict patients' overall survival using both internal and external datasets. Moreover, a strong correlation was revealed between the signaling pathway, immune cell infiltration, immunotherapy response, and risk score. Importantly, a novel potential drug candidate for HCC treatment was discovered based on the risk score and also validated through ex vivo experiments. Our finds offer a novel perspective on prognosis prediction and drug exploration for cancer patients.
    MeSH term(s) Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Liver Neoplasms/immunology ; Humans ; Immunotherapy/methods ; Prognosis ; Gene Expression Regulation, Neoplastic/drug effects ; Biomarkers, Tumor/genetics ; Drug Resistance, Neoplasm/genetics ; Signal Transduction/drug effects
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-59877-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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