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  1. Book ; Online: Designing explainable artificial intelligence with active inference

    Albarracin, Mahault / Hipólito, Inês / Tremblay, Safae Essafi / Fox, Jason G. / René, Gabriel / Friston, Karl / Ramstead, Maxwell J. D.

    A framework for transparent introspection and decision-making

    2023  

    Abstract: This paper investigates the prospect of developing human-interpretable, explainable artificial intelligence (AI) systems based on active inference and the free energy principle. We first provide a brief overview of active inference, and in particular, of ...

    Abstract This paper investigates the prospect of developing human-interpretable, explainable artificial intelligence (AI) systems based on active inference and the free energy principle. We first provide a brief overview of active inference, and in particular, of how it applies to the modeling of decision-making, introspection, as well as the generation of overt and covert actions. We then discuss how active inference can be leveraged to design explainable AI systems, namely, by allowing us to model core features of ``introspective'' processes and by generating useful, human-interpretable models of the processes involved in decision-making. We propose an architecture for explainable AI systems using active inference. This architecture foregrounds the role of an explicit hierarchical generative model, the operation of which enables the AI system to track and explain the factors that contribute to its own decisions, and whose structure is designed to be interpretable and auditable by human users. We outline how this architecture can integrate diverse sources of information to make informed decisions in an auditable manner, mimicking or reproducing aspects of human-like consciousness and introspection. Finally, we discuss the implications of our findings for future research in AI, and the potential ethical considerations of developing AI systems with (the appearance of) introspective capabilities.
    Keywords Computer Science - Artificial Intelligence
    Subject code 120
    Publishing date 2023-06-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online ; Thesis: Differential DNA methylation profiles modulating phenotypes

    Cortese, Rene Gabriel [Verfasser]

    regions of tissue-specific DNA methylation and their relation to gene expression, their evolutionary conservation and their application as molecular biomarkers

    2008  

    Author's details vorgelegt von Rene Gabriel Cortese
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Article ; Online: Cervical ripening in prolonged pregnancies by silicone double balloon catheter versus vaginal dinoprostone slow release system

    Caroline Diguisto / Amélie Le Gouge / Chloé Arthuis / Norbert Winer / Olivier Parant / Christophe Poncelet / Celine Chauleur / Jacob Hannigsberg / Guillaume Ducarme / Denis Gallot / Rene Gabriel / Raoul Desbriere / Gael Beucher / Cyrille Faraguet / Helene Isly / Patrick Rozenberg / Bruno Giraudeau / Franck Perrotin / Groupe de Recherche en Obstétrique et Gynécologie (GROG)

    PLoS Medicine, Vol 18, Iss 2, p e

    The MAGPOP randomised controlled trial.

    2021  Volume 1003448

    Abstract: Background Prolonged pregnancies are a frequent indication for induction of labour. When the cervix is unfavourable, cervical ripening before oxytocin administration is recommended to increase the likelihood of vaginal delivery, but no particular method ... ...

    Abstract Background Prolonged pregnancies are a frequent indication for induction of labour. When the cervix is unfavourable, cervical ripening before oxytocin administration is recommended to increase the likelihood of vaginal delivery, but no particular method is currently recommended for cervical ripening of prolonged pregnancies. This trial evaluates whether the use of mechanical cervical ripening with a silicone double balloon catheter for induction of labour in prolonged pregnancies reduces the cesarean section rate for nonreassuring fetal status compared with pharmacological cervical ripening by a vaginal pessary for the slow release of dinoprostone (prostaglandin E2). Methods and findings This is a multicentre, superiority, open-label, parallel-group, randomised controlled trial conducted in 15 French maternity units. Women with singleton pregnancies, a vertex presentation, ≥41+0 and ≤42+0 weeks' gestation, a Bishop score <6, intact membranes, and no history of cesarean delivery for whom induction of labour was decided were randomised to either mechanical cervical ripening with a Cook Cervical Ripening Balloon or pharmacological cervical ripening by a Propess vaginal pessary serving as a prostaglandin E2 slow-release system. The primary outcome was the rate of cesarean for nonreassuring fetal status, with an independent endpoint adjudication committee determining whether the fetal heart rate was nonreassuring. Secondary outcomes included delivery (time from cervical ripening to delivery, number of patients requiring analgesics), maternal and neonatal outcomes. Between January 2017 and December 2018, 1,220 women were randomised in a 1:1 ratio, 610 allocated to a silicone double balloon catheter, and 610 to the Propess vaginal pessary for the slow release of dinoprostone. The mean age of women was 31 years old, and 80% of them were of white ethnicity. The cesarean rates for nonreassuring fetal status were 5.8% (35/607) in the mechanical ripening group and 5.3% (32/609) in the pharmacological ripening group ...
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: Designing Ecosystems of Intelligence from First Principles

    Friston, Karl J / Ramstead, Maxwell J D / Kiefer, Alex B / Tschantz, Alexander / Buckley, Christopher L / Albarracin, Mahault / Pitliya, Riddhi J / Heins, Conor / Klein, Brennan / Millidge, Beren / Sakthivadivel, Dalton A R / Smithe, Toby St Clere / Koudahl, Magnus / Tremblay, Safae Essafi / Petersen, Capm / Fung, Kaiser / Fox, Jason G / Swanson, Steven / Mapes, Dan /
    René, Gabriel

    2022  

    Abstract: This white paper lays out a vision of research and development in the field of artificial intelligence for the next decade (and beyond). Its denouement is a cyber-physical ecosystem of natural and synthetic sense-making, in which humans are integral ... ...

    Abstract This white paper lays out a vision of research and development in the field of artificial intelligence for the next decade (and beyond). Its denouement is a cyber-physical ecosystem of natural and synthetic sense-making, in which humans are integral participants -- what we call ''shared intelligence''. This vision is premised on active inference, a formulation of adaptive behavior that can be read as a physics of intelligence, and which inherits from the physics of self-organization. In this context, we understand intelligence as the capacity to accumulate evidence for a generative model of one's sensed world -- also known as self-evidencing. Formally, this corresponds to maximizing (Bayesian) model evidence, via belief updating over several scales: i.e., inference, learning, and model selection. Operationally, this self-evidencing can be realized via (variational) message passing or belief propagation on a factor graph. Crucially, active inference foregrounds an existential imperative of intelligent systems; namely, curiosity or the resolution of uncertainty. This same imperative underwrites belief sharing in ensembles of agents, in which certain aspects (i.e., factors) of each agent's generative world model provide a common ground or frame of reference. Active inference plays a foundational role in this ecology of belief sharing -- leading to a formal account of collective intelligence that rests on shared narratives and goals. We also consider the kinds of communication protocols that must be developed to enable such an ecosystem of intelligences and motivate the development of a shared hyper-spatial modeling language and transaction protocol, as a first -- and key -- step towards such an ecology.

    Comment: 23+18 pages, one figure, one six page appendix
    Keywords Computer Science - Artificial Intelligence ; Computer Science - Multiagent Systems ; Nonlinear Sciences - Adaptation and Self-Organizing Systems
    Subject code 401
    Publishing date 2022-12-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book: Parvovirose canine

    Fabries, Lionel René Gabriel Henri

    virologie, immunologie, immunoprophylaxie et contribution aux essais cliniques sur le terrain d'un vaccin homologue à virus modifié

    (Toulouse. École nationale vétérinaire. Thes̀e ; 1982, no. 83)

    1982  

    Title translation Canine parvoviral diseases.
    Author's details par Lionel, René, Gabriel, Henri Fabries. --
    Series title Toulouse. École nationale vétérinaire. Thes̀e ; 1982, no. 83
    Language French
    Size 118, [3] p. :, ill. ;, 24 cm. --
    Publisher École nationale vétérinaire
    Publishing place Toulouse
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  6. Book ; Thesis: Parvovirose canine

    Fabries, Lionel René Gabriel Henri

    virologie, immunologie, immunoprophylaxie et contribution aux essais cliniques sur le terrain d'un vaccin homologue à virus modifié

    1982  

    Author's details par Lionel René Gabriel Henri Fabries
    Language French
    Size 118 S, graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ecole Nat. Vét., Diss.--Toulouse, 1982
    Database Special collection on veterinary medicine and general parasitology

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  7. Book ; Thesis: L'ours brun

    Thomas, Yves René Gabriel

    le déclin de l'espèce en Europe et en France ; les conditions de sa survie dans les Pyrénées françaises

    1975  

    Author's details par Yves René Gabriel Thomas
    Language French
    Size 72 S, graph. Darst., Kt
    Document type Book ; Thesis
    Thesis / German Habilitation thesis École Nat. Vét., Diss.--Toulouse, 1975
    Database Special collection on veterinary medicine and general parasitology

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  8. Book ; Thesis: Contribution à la thérapeutique des affections kérato-conjonctivales des petits carnivores par le viscobiotic

    Carrère, René Gabriel Jean

    1965  

    Author's details par René Gabriel Jean Carrère
    Language French
    Size 56 S
    Document type Book ; Thesis
    Thesis / German Habilitation thesis École Nat. Vét., Diss.--Toulouse, 1965
    Database Special collection on veterinary medicine and general parasitology

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  9. Book: The humicolous fauna of South Africa

    Jeannel, René Gabriel / Lelup, N

    Pselaphidae and Catopidae (Coleoptera) Scientific results [of the] N. Leleup expedition 1960-1961

    (Memoir ; no. 15)

    1964  

    Institution N. Lelup Expedition, 1960-61
    Series title Memoir ; no. 15
    Keywords Beetles
    Language French
    Size 261 p., illus., maps., 28 cm.
    Publisher Transvaal Museum
    Publishing place Pretoria
    Document type Book
    Note French with English summaries.
    Database NAL-Catalogue (AGRICOLA)

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  10. Book: Géonémie des Pselaphides de l'Afrique intertropicale

    Jeannel, René Gabriel

    (Mémoires du Muséum national d'histoire naturelle. ; nouv. sér., t.2, no.1)

    1950  

    Series title Mémoires du Muséum national d'histoire naturelle. ; nouv. sér., t.2, no.1
    Keywords Pselaphidae.
    Language French
    Size 48 p.
    Publisher Editions du Museum
    Publishing place Paris
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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