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Article ; Online: Bilan d’imagerie et orientation diagnostique des cancers des voies aérodigestives supérieures.

Gaultier, Anne-Laure / Reverdito, Guillaume / Saltel-Fulero, Aurélien

2023 Volume 72, Issue 10, Page(s) 1080–1085

Abstract: The upper aerodigestive tract (UADT) has a complex anatomical architecture, which is only partially accessible by clinical examination and for which a detailed imaging analysis is necessary to assist in decision making and therapeutic planning. The ... ...

Title translation	Imaging assessment and diagnostic guidance of upper aerodigestive tract cancers.
Abstract	The upper aerodigestive tract (UADT) has a complex anatomical architecture, which is only partially accessible by clinical examination and for which a detailed imaging analysis is necessary to assist in decision making and therapeutic planning. The quality of image interpretation by the radiologist will benefit from the clinical elements provided by the referring physician. In addition to the topographical and morphological information of the tumor, the imaging report will specify the deep extensions, in particular peri-nerve, endocranial, orbital, deep cervical, cartilaginous and infra-glottic, which are often underestimated at the clinical examination. The close collaboration between specialized radiologists and clinicians contributes to a better management of the patient's tumor pathology.
MeSH term(s)	Humans ; Head and Neck Neoplasms/diagnostic imaging
Language	French
Publishing date	2023-02-22
Publishing country	France
Document type	English Abstract ; Journal Article
ZDB-ID	205365-2
ISSN	2101-017X ; 0035-2640
ISSN (online)	2101-017X
ISSN	0035-2640
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Ua VI Zs.433: Show issues

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Article ; Online: Ruptured pulmonary artery pseudoaneurysm treated with stent graft: case report and literature review.

Barrot, Valère / Pellerin, Olivier / Reverdito, Guillaume / Sapoval, Marc / Boeken, Tom

CVIR endovascular

2022 Volume 5, Issue 1, Page(s) 59

Abstract: Background: Hemoptysis is a severe condition, associated with a high mortality rate from asphyxiation. Less than 5% of cases come from the pulmonary arterial circulation and large pseudoaneurysm are rarely treatable by stent graft.: Case presentation!# ...

Abstract	Background: Hemoptysis is a severe condition, associated with a high mortality rate from asphyxiation. Less than 5% of cases come from the pulmonary arterial circulation and large pseudoaneurysm are rarely treatable by stent graft. Case presentation: We present the case of a 74-year-old man who suffered from a new onset of hemoptysis despite a prior bronchial artery embolization. He underwent a rescue endovascular stent graft placement for a massive hemoptysis caused by a ruptured proximal pulmonary artery pseudoaneurysm. A short review of similar situations is provided. Conclusion: Salvage endovascular stent graft placement for a massive hemoptysis caused by a ruptured proximal pulmonary artery pseudoaneurysm is a viable salvage technique for life-threatening hemoptysis.
Language	English
Publishing date	2022-11-22
Publishing country	Switzerland
Document type	Journal Article
ISSN	2520-8934
ISSN (online)	2520-8934
DOI	10.1186/s42155-022-00339-6
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Article: Acute digit ischemia due to a ruptured digital collateral artery aneurysm in a patient of hemophilia: A case report.

Dukan, Ruben / Lacroix, Maxime / Bertin, Emilie / Reverdito, Guillaume / Fitoussi, Franck / Binder, Adeline Cambon

Journal of orthopaedic case reports

2023 Volume 13, Issue 11, Page(s) 70–74

Abstract: Introduction: Digital artery aneurysms are a rare event but cases have been reported in the literature. The hemostasis disorders make these aneurysms particularly dangerous with potentially irreversible hand complications: Compression of adjacent ... ...

Abstract	Introduction: Digital artery aneurysms are a rare event but cases have been reported in the literature. The hemostasis disorders make these aneurysms particularly dangerous with potentially irreversible hand complications: Compression of adjacent vascular and nervous structures, embolization of associated thrombi, finger ischemia, and necrosis. Case report: We reported a case of digital ischemia due to a ruptured aneurysm of a digital collateral artery, leading to the diagnosis of congenital hemophilia A. Hematoma evacuation allowed finger revascularization. Complete symptom resolution required ligature excision associated with Factor VIII supplementation. Conclusion: Aneurysms of the digital collateral arteries are a rare event. In the case of a hemophilic patient, surgical management is necessary, and medical treatment alone is not sufficient. The consequences of a ruptured aneurysm in this type of patient can be serious. A close monitoring is required to ensure the absence of early recurrence.
Language	English
Publishing date	2023-11-19
Publishing country	India
Document type	Case Reports
ZDB-ID	2658169-3
ISSN	2250-0685
ISSN	2250-0685
DOI	10.13107/jocr.2023.v13.i11.4010
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Article ; Online: Challenge of a therapeutic sequence: rare case of heart failure in mitral valvular disease intensified by an extreme mediastinal shift from major diaphragmatic eventration.

Le Pimpec-Barthes, Françoise / Al Zreibi, Charles / Reverdito, Guillaume / Leprince, Pascal

Interactive cardiovascular and thoracic surgery

2022 Volume 35, Issue 3

Abstract: Extreme mediastinal shift due to major diaphragm eventration is complex when mitral-valve repair is required. We report the case of a 59-year-old woman with diaphragmatic eventration who had 2 recent episodes of heart failure due to arrythmia associated ... ...

Abstract	Extreme mediastinal shift due to major diaphragm eventration is complex when mitral-valve repair is required. We report the case of a 59-year-old woman with diaphragmatic eventration who had 2 recent episodes of heart failure due to arrythmia associated with severe mitral-valve regurgitation (regurgitant orifice area 47 mm2). Forced expiratory flow-volume in the first second and vital capacity (VC) were at 32% and 33%, respectively,decreasing to 20% and 30% when she was in a supine position. We found it impossible to repair the valve first because of the extreme mediastinal shift and respiratory dysfunction. Therefore, we decided to perform diaphragm plication first followed 3 months later by mitral valve repair. Six months after the cardiac operation, the patient showed significant clinical improvement. Forced expiratory flow-volume in the first second and vital capacity increased to 58% and 55%, respectively. The decision to perform the thoracic operation first, followed by the cardiac operation, was the key to improving the patient's respiratory function and to medializing the heart to safely support cardiac surgery.
MeSH term(s)	Diaphragm/diagnostic imaging ; Diaphragm/surgery ; Diaphragmatic Eventration/surgery ; Female ; Heart Failure/complications ; Heart Failure/surgery ; Humans ; Middle Aged ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery
Language	English
Publishing date	2022-09-12
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivac181
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Zs.A 5730: Show issues

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Article ; Online: Middle lobe suffering due to malposition and 180° tilt of the 2 remaining lobes after right upper lobectomy.

Janet-Vendroux, Aurelie / Al Zreibi, Charbel / Reverdito, Guillaume / Arame, Alex / Badia, Alain / Masmoudi, Hicham / Messaoudi, Houssem / Le Pimpec-Barthes, Francoise

Interdisciplinary cardiovascular and thoracic surgery

2023 Volume 36, Issue 2

Abstract: Middle lobe (ML) suffering after right upper lobectomy (RUL) is rare but represents a major complication usually due to lobar torsion. We report 3 atypical consecutive cases of ML suffering due to malposition of the 2 remaining right lobes with a 180° ... ...

Abstract	Middle lobe (ML) suffering after right upper lobectomy (RUL) is rare but represents a major complication usually due to lobar torsion. We report 3 atypical consecutive cases of ML suffering due to malposition of the 2 remaining right lobes with a 180° tilt. All 3 female patients had surgery for non-small-cell carcinoma including RUL associated with radical hilar and mediastinal lymph node removal. Postoperative chest X-ray abnormalities appeared at days 1-3 respectively. The diagnosis of malposition of the 2 lobes was done on contrast-enhanced chest CT scan at days 7, 7 and 6, respectively. A reoperation for suspected ML torsion was required in all patients. Three repositionings of the 2 lobes and 1 middle lobectomy were performed. The postoperative courses were then uneventful, and the 3 patients were alive at a mean follow-up of 12 months. Before thoracic approach closure after RUL, systematic check of good positioning of the 2 reinflated remaining lobes is indispensable. It may prevent ML suffering secondary to 180° lobar tilt leading to whole pulmonary malposition.
Language	English
Publishing date	2023-02-22
Publishing country	England
Document type	Journal Article
ISSN	2753-670X
ISSN (online)	2753-670X
DOI	10.1093/icvts/ivad038
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Article ; Online: VEGF-A plasma levels are associated with impaired DLCO and radiological sequelae in long COVID patients.

Philippe, Aurélien / Günther, Sven / Rancic, Jeanne / Cavagna, Pauline / Renaud, Bertrand / Gendron, Nicolas / Mousseaux, Elie / Hua-Huy, Thông / Reverdito, Guillaume / Planquette, Benjamin / Sanchez, Olivier / Gaussem, Pascale / Salmon, Dominique / Diehl, Jean-Luc / Smadja, David M

Angiogenesis

2023 Volume 27, Issue 1, Page(s) 51–66

Abstract: Background: Long COVID, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent clinical symptoms following COVID-19.: Objective: To correlate biomarkers of endothelial dysfunction with persistent clinical symptoms and ... ...

Abstract	Background: Long COVID, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent clinical symptoms following COVID-19. Objective: To correlate biomarkers of endothelial dysfunction with persistent clinical symptoms and pulmonary function defects at distance from COVID-19. Methods: Consecutive patients with long COVID-19 suspicion were enrolled. A panel of endothelial biomarkers was measured in each patient during clinical evaluation and pulmonary function test (PFT). Results: The study included 137 PASC patients, mostly male (68%), with a median age of 55 years. A total of 194 PFTs were performed between months 3 and 24 after an episode of SARS-CoV-2 infection. We compared biomarkers evaluated in PASC patients with 20 healthy volunteers (HVs) and acute hospitalized COVID-19 patients (n = 88). The study found that angiogenesis-related biomarkers and von Willebrand factor (VWF) levels were increased in PASC patients compared to HVs without increased inflammatory or platelet activation markers. Moreover, VEGF-A and VWF were associated with persistent lung CT scan lesions and impaired diffusing capacity of the lungs for carbon monoxide (DLCO) measurement. By employing a Cox proportional hazards model adjusted for age, sex, and body mass index, we further confirmed the accuracy of VEGF-A and VWF. Following adjustment, VEGF-A emerged as the most significant predictive factor associated with persistent lung CT scan lesions and impaired DLCO measurement. Conclusion: VEGF-A is a relevant predictive factor for DLCO impairment and radiological sequelae in PASC. Beyond being a biomarker, we hypothesize that the persistence of angiogenic disorders may contribute to long COVID symptoms.
MeSH term(s)	Humans ; Male ; Middle Aged ; Female ; Post-Acute COVID-19 Syndrome ; Vascular Endothelial Growth Factor A ; von Willebrand Factor ; COVID-19/diagnostic imaging ; SARS-CoV-2 ; Disease Progression ; Biomarkers
Chemical Substances	Vascular Endothelial Growth Factor A ; von Willebrand Factor ; Biomarkers
Language	English
Publishing date	2023-08-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1484717-6
ISSN	1573-7209 ; 0969-6970
ISSN (online)	1573-7209
ISSN	0969-6970
DOI	10.1007/s10456-023-09890-9
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Zs.A 5094: Show issues

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Article ; Online: Diastolic Function Assessment of Left and Right Ventricles by MRI in Systemic Sclerosis Patients.

Mousseaux, Elie / Agoston-Coldea, Lucia / Marjanovic, Zora / Baudet, Mathilde / Reverdito, Guillaume / Bollache, Emilie / Kachenoura, Nadjia / Messas, Emmanuel / Soulat, Gilles / Farge, Dominique

Journal of magnetic resonance imaging : JMRI

2022 Volume 56, Issue 5, Page(s) 1416–1426

Abstract: Background: Heart involvement is frequent although often clinically silent in systemic sclerosis (SSc) patients. Early identification of cardiac involvement can be improved by noninvasive methods such as MRI, in addition to transthoracic ... ...

Abstract	Background: Heart involvement is frequent although often clinically silent in systemic sclerosis (SSc) patients. Early identification of cardiac involvement can be improved by noninvasive methods such as MRI, in addition to transthoracic echocardiography (TTE). Purpose: To assess the ability of phase-contrast (PC)-MRI to detect subclinical left (LV) and right (RV) ventricular diastolic dysfunction in SSc patients. Study type: Prospective. Population: Thirty-five consecutive SSc patients (49 ± 14 years) and 35 sex- and age-matched healthy controls (48.6 ± 13.5 years) who underwent TTE and MRI in the same week. Field strength/sequence: 5 T/PC-MRI using a breath-hold velocity-encoded gradient echo sequence. Assessment: LV TTE (E/E') and LV and RV PC-MRI indices of diastolic function (LV early and late transmitral [E Statistical tests: Two-tailed t-test, Wilcoxon test, or Fischer test for comparison of variables between SSc and healthy control groups; sensitivity, specificity, receiver-operating-characteristic (ROC) area under the curve (AUC) to assess discriminative ability of variables. A P-value <0.05 was considered statistically significant. Results: TTE LV E/E' and MRI E Data conclusion: MRI was able to detect LV and RV diastolic dysfunction in SSc patients with good accuracy in the absence of LV systolic dysfunction at echocardiography. Use of MRI can allow to better assess the early impact of myocardial fibrosis related to SSc. Level of evidence: 1 TECHNICAL EFFICACY STAGE: 2.
MeSH term(s)	Adult ; Diastole ; Heart Ventricles/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Prospective Studies ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/diagnostic imaging ; Ventricular Dysfunction ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Function, Left
Language	English
Publishing date	2022-03-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1146614-5
ISSN	1522-2586 ; 1053-1807
ISSN (online)	1522-2586
ISSN	1053-1807
DOI	10.1002/jmri.28143
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Zs.A 3648: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Visual lung damage CT score at hospital admission of COVID-19 patients and 30-day mortality.

Charpentier, Etienne / Soulat, Gilles / Fayol, Antoine / Hernigou, Anne / Livrozet, Marine / Grand, Teodor / Reverdito, Guillaume / Al Haddad, Jad / Dang Tran, Kim Diep / Charpentier, Anne / Clement, Olivier / Hulot, Jean-Sebastien / Mousseaux, Elie

European radiology

2021 Volume 31, Issue 11, Page(s) 8354–8363

Abstract: Objectives: Chest CT has been widely used to screen and to evaluate the severity of COVID-19 disease in the early stages of infection without severe acute respiratory syndrome, but no prospective data are available to study the relationship between ... ...

Abstract	Objectives: Chest CT has been widely used to screen and to evaluate the severity of COVID-19 disease in the early stages of infection without severe acute respiratory syndrome, but no prospective data are available to study the relationship between extent of lung damage and short-term mortality. The objective was to evaluate association between standardized simple visual lung damage CT score (vldCTs) at admission, which does not require any software, and 30-day mortality. Methods: In a single-center prospective cohort of COVID-19 patients included during 4 weeks, the presence and extent of ground glass opacities(GGO), consolidation opacities, or both of them were visually assessed in each of the 5 lung lobes (score from 0 to 4 per lobe depending on the percentage and out of 20 per patient = vldCTs) after the first chest CT performed to detect COVID-19 pneumonia. Results: Among 210 confirmed COVID-19 patients, the number of survivors and non-survivors was 162 (77%) and 48 (23%), respectively at 30 days. vldCTs was significantly higher in non-survivors, and the AUC of vldCTs to distinguish survivors and non-survivors was 0.72 (95%CI 0.628-0.807, p < 0.001); the best cut-off vldCTs value was 7. During follow-up, significant differences in discharges and 30-day mortality were observed between patients with vldCTs ≥ 7 versus vldCTs < 7: (98 [85.2%] vs 49 [51.6%]; p < 0.001 and 36 [37.9%] vs 12 [12.4%]; p < 0.001, respectively. The 30-day mortality increased if vldCTs ≥ 7 (HR, 3.16 (1.50-6.43); p = 0.001), independent of age, respiratory rate and oxygen saturation levels, and comorbidities at admission. Conclusions: By using chest CT in COVID-19 patients, extensive lung damage can be visually assessed with a score related to 30-day mortality independent of conventional risk factors of the disease. Key points: • In non-selected COVID-19 patients included prospectively during 4 weeks, the extent of ground glass opacities(GGO) and consolidation opacities evaluated by a simple visual score was related to 30-day mortality independent of age, respiratory rate, oxygen saturation levels, comorbidities, and hs-troponin I level at admission. • This severity score should be incorporated into risk stratification algorithms and in structured chest CT reports requiring a standardized reading by radiologists in case of COVID-19.
MeSH term(s)	COVID-19 ; Hospitals ; Humans ; Lung/diagnostic imaging ; Prospective Studies ; SARS-CoV-2 ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-04-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-021-07938-2
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