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  1. Article ; Online: Review of Alloy Containing Bismuth Oxide Nanoparticles on X-Ray Absorption in Radiology Shields

    Omid Zare / Reza Afzalipour / Mohammad Sadegh Golvardi Yazdi

    Disease and Diagnosis, Vol 11, Iss 1, Pp 31-

    2022  Volume 35

    Abstract: Background: Managing potential risks that can threaten the health of medical staff including risks associated with treatment tools and equipment has always played an important role in the healthcare systems. This study aimed to investigate the ... ...

    Abstract Background: Managing potential risks that can threaten the health of medical staff including risks associated with treatment tools and equipment has always played an important role in the healthcare systems. This study aimed to investigate the documentation on the effect of nanoparticle shields on the absorption of hazardous radiation in radiology, and specifically alloy containing bismuth oxide )Bi2O3) nanoparticles. Materials and Methods: Several databases including ScienceDirect, Web of Science, Scopus, PubMed, and Magiran were searched to collect the required documents. The articles were selected based on the year of publication and their relationship with the subject and objectives. Results: Studies confirm the effectiveness of bismuth oxide nanoparticles in order to protect against radiation in different types of radiological shields. These findings show the relationship between different parameters of nanoparticles and their effect on radiation absorption, such as the size of nanoparticles, used kilovoltage peak )kVp), thickness of shields, density of nanoparticles, as well as different methods of using these particles in different types of radiological shields. Conclusion: Bismuth oxide nanoparticles have a significant effect on the absorption of X-rays in radiology. Using these particles results in lighter shields with lower cost and lead content. In particular, bismuth oxide nanoparticles are very efficient at absorbing radiation and reducing the cost of production for shields.
    Keywords nanoparticles ; bismuth oxide ; x-ray ; radiological shields ; Medicine ; R
    Subject code 620
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hormozgan University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Scatter Radiation Absorbed Dose Distribution in Coronary Angiography

    Seyed Abdolhamid Talebi / Salman Jafari / Reza Afzalipour / Faraj Tabeie / Seyed Pezhman Shirmardi

    Iranian Journal of Medical Physics, Vol 19, Iss 4, Pp 250-

    A Measurement-Based Study

    2022  Volume 257

    Abstract: Introduction: This study aimed to investigate the absorbed dose of scatter radiation in coronary angiography.Material and Methods: The scatter radiation dose was measured for 20 patients at four different heights (50,100, 150, and 165 cm) from the floor. ...

    Abstract Introduction: This study aimed to investigate the absorbed dose of scatter radiation in coronary angiography.Material and Methods: The scatter radiation dose was measured for 20 patients at four different heights (50,100, 150, and 165 cm) from the floor. The spatial dose was measured by RTI Piranha r100b solid-state dose probe at different points around the patient in an actual clinical situation and with a phantom. Also, the measurement was repeated using a designed phantom in fluoroscopy and cine mode in posterior anterior (PA), left lateral (LLAT), left posterior oblique (LPO45°), right posterior oblique (RPO45°), and right-lateral (RLAT)projections . Organ-absorbed doses were normalized to dose area product (DAP). Results: The dose rate at different heights between the projections on the patient and the phantom as well as organ dose DAP conversion coefficients were different (p˂0.05). It was found that the dose rate changes in fluoroscopic mode compared to cine mode are significantly different (p = 0.001). The dose rate in cine mode is approximately four times that in fluoroscopy mode. The dose rate around the cardiologist's waist could be reduced by 37 – 43 % with a displacement of 20cm away. In this study, the effective dose rate received by the cardiologist’s eyes was higher than those reported by ICRP.Conclusion: Taking a suitable projection could reduce the dose rate delivered to the angiography team. Further studies should be conducted about the effect of different projections with the same clinical use on dose distribution in coronary angiography to provide the best working conditions for physicians and staff.
    Keywords angiography ; radiation dosages ; radiation dosimeter ; fluoroscopy ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 616
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Mashhad University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Pregnant Women and Infants Infected with SARS-COV-2

    Omolbanin Delashoub / Salman Jafari / Mohammad Saleh Hajializadeh / Hamid Abdollahi / Reza Afzalipour

    Disease and Diagnosis, Vol 9, Iss 2, Pp 92-

    A Brief Overview

    2020  Volume 95

    Abstract: Coronavirus disease 2019 (COVID-19) is now a global health concern and a wide range of people are at risk. Pregnant women are considered high-risk groups due to hormonal changes and weakness in the immune system. In the present study, the transmission of ...

    Abstract Coronavirus disease 2019 (COVID-19) is now a global health concern and a wide range of people are at risk. Pregnant women are considered high-risk groups due to hormonal changes and weakness in the immune system. In the present study, the transmission of COVID-19 from mother to fetus and infection of children under the age of 10 with this virus were discussed. This study tries to investigate whether the coronavirus can be transmitted from a pregnant mother to her fetus and whether the virus can be transmitted to the baby through breast milk. According to researchers, children under the age of 10 do not get the disease; however, the first case of a baby with coronavirus was reported in Mashhad, Iran, based on the world’s up-to-date studies and the perceptions of medical experts.
    Keywords covid-19 ; coronavirus ; pregnant women ; children ; pcr ; ct-scan ; Medicine ; R
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Hormozgan University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Evaluation of Lomustine-Loaded Iron Nanoparticles on Caspase-6 Gene Expression and Cell Viability in U87Mg Cell Line

    Zeinolabedin Sharifian Dastjerdi / Elyas Kargar Abargouei / Salman Jafari / Ebrahim Eftekhar / Majid Pourentezari / Fahimeh Zamani Rarani / Reza Afzalipour / Javad Mohajer Ansari / Mohammad Zamani Rarani

    Disease and Diagnosis, Vol 9, Iss 3, Pp 124-

    2020  Volume 129

    Abstract: Background: Every year, many people around the world die from cancers. Among all types of cancers, brain cancer has been recognized as one of the most deadly cancers due to the late detection and limitations of current therapies, and thus it remains an ... ...

    Abstract Background: Every year, many people around the world die from cancers. Among all types of cancers, brain cancer has been recognized as one of the most deadly cancers due to the late detection and limitations of current therapies, and thus it remains an unresolved problem. Glioblastoma occurs in different parts of the central nervous system and is one of the most important causes of cancer death in people. In addition, there are many problems for the treatment of cancer cells. One of the limiting factors is the resistance of cancer cells to chemotherapy drugs. In this regard, the use of nanoparticles (NPs) is an effective method for overcoming this problem. Materials and Methods: In this study, iron oxide-NPs were synthesized and loaded on the folic and lomustine. Further, the size and morphology of NPs were assessed by transmission electron microscopy, X-ray photoelectron spectroscopy, and dynamic light scattering. Then, the U87-MG cell line was cultured in the Dulbecco’s Modified Eagle Medium and treated with nano, nano-folic, nano-lomustine (LUM), LUM, and complex, followed by evaluating 50% inhibitory concentration, tetrazolium assay, and caspase-6 activity. Results: Our results showed that cell viability decreased in LUM container groups by increasing the incubation time. Based on the caspase-6 activity analysis, the mortality rate increased in LUM container groups after 3 days. These findings indicated that LUM, complex, and nano-LUM increase cell death in U87MG. Conclusion: Finally, the results suggested that LUM in NPs could be applied as a safer form of drug delivery for targeting cancer.
    Keywords targeted therapy ; nanoparticle ; apoptosis ; caspase ; u87mg ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Hormozgan University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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