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  1. Article ; Online: Potenzielle Patientengefährdung durch europakonforme Neuregulierung auch in der Adipositaschirurgie.

    Rheinwalt, Karl Peter / Plamper, Andreas

    Chirurgie (Heidelberg, Germany)

    2023  Volume 94, Issue 7, Page(s) 648–650

    Title translation Potential danger to patients due to European new regulation also in obesity surgery.
    MeSH term(s) Humans ; Bariatric Surgery/adverse effects ; Obesity, Morbid/surgery ; Patients
    Language German
    Publishing date 2023-06-19
    Publishing country Germany
    Document type Letter
    ISSN 2731-698X
    ISSN (online) 2731-698X
    DOI 10.1007/s00104-023-01917-7
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  2. Book ; Thesis: Risikoprofile koronarrevaskularisierter Patienten höheren Lebensalters

    Rheinwalt, Karl P.

    1989  

    Author's details vorgelegt von Karl Peter Rheinwalt
    Size 131 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Diss., 1990
    HBZ-ID HT003827013
    Database Catalogue ZB MED Medicine, Health

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  3. Conference proceedings: Stellenwert des laparoskopischen 1-Anastomosen-Magenbypass in der Adipositaschirurgie

    Rheinwalt, Karl

    2013  , Page(s) 13dgch195

    Event/congress 130. Kongress der Deutschen Gesellschaft für Chirurgie; München; Deutsche Gesellschaft für Chirurgie; 2013
    Keywords Medizin, Gesundheit
    Publishing date 2013-04-26
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/13dgch195
    Database German Medical Science

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  4. Article ; Online: Stage of fibrosis is not a predictive determinant of weight loss in patients undergoing bariatric surgery.

    Brol, Maximilian Joseph / Drebber, Uta / Yu, Xiaojie / Schierwagen, Robert / Gu, Wenyi / Plamper, Andreas / Klein, Sabine / Odenthal, Margarete / Uschner, Frank Erhard / Praktiknjo, Michael / Trebicka, Jonel / Rheinwalt, Karl Peter

    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

    2024  

    Abstract: Background: Obesity and nonalcoholic fatty liver disease (NAFLD) are an increasing health care burden worldwide. Weight loss is currently the best option to alleviate NAFLD and is efficiently achieved by bariatric surgery. Presence of NAFLD seems to be ... ...

    Abstract Background: Obesity and nonalcoholic fatty liver disease (NAFLD) are an increasing health care burden worldwide. Weight loss is currently the best option to alleviate NAFLD and is efficiently achieved by bariatric surgery. Presence of NAFLD seems to be predictive for postoperative weight loss. To date, only few predictive factors for postbariatric weight loss (age, diabetes, psychiatric disorders) are established.
    Objectives: Since liver fibrosis is the pathogenic driver for the progression of liver disease, we investigated its role in predicting postoperative weight loss. This study focuses on the correlation between fibrosis stage and weight loss.
    Setting: University and university-affiliated cooperation, Germany.
    Methods: We used a prospective, single-center cohort study including 164 patients who underwent bariatric surgery with simultaneous liver biopsies. Liver fibrosis was determined histologically according to Kleiner score and noninvasively by APRI and FIB-4 score. Percentage of total body weight loss was calculated at 1-year follow up visit.
    Results: Thirty-two patients were found without fibrosis, whereas 91 patients showed mild fibrosis (F1), 37 significant fibrosis (F2), and only 4 patients presented advanced fibrosis (F3) at the time of bariatric surgery. Weight loss was similar across different degrees of fibrosis stage. Accordingly, linear regression analysis did not identify predictors of weight loss among fibrosis scores. In multivariable analysis, age and presence of diabetes showed the strongest predictive value.
    Conclusions: Baseline presence of fibrosis was not associated with postoperative weight loss, while age and diabetes were independent predictors of weight loss. Bariatric surgery should be applied independently of the fibrosis stage.
    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2274243-8
    ISSN 1878-7533 ; 1550-7289
    ISSN (online) 1878-7533
    ISSN 1550-7289
    DOI 10.1016/j.soard.2024.02.006
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  5. Article ; Online: The First Report of One Anastomosis Gastric Bypass in a Patient with Intestinal Malrotation.

    Plamper, Andreas / Kakuan, Mana / Conejero, Fabio Russo / Parmar, Chetan / Rheinwalt, Karl

    Obesity surgery

    2021  Volume 31, Issue 7, Page(s) 3317–3319

    MeSH term(s) Digestive System Abnormalities ; Gastric Bypass ; Humans ; Intestinal Volvulus/surgery ; Obesity, Morbid/surgery
    Language English
    Publishing date 2021-03-15
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-021-05346-5
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  6. Article ; Online: Telomere length dynamics measured by flow-FISH in patients with obesity undergoing bariatric surgery.

    Rolles, Benjamin / Ferreira, Monica S V / Vieri, Margherita / Rheinwalt, Karl P / Schmitz, Sophia M / Alizai, Patrick H / Neumann, Ulf / Brümmendorf, Tim H / Beier, Fabian / Ulmer, Tom F / Tometten, Mareike

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 304

    Abstract: Obesity has negative effects on comorbidities, health-related quality of life and survival. Telomere length (TL) changes after bariatric surgery have been reported, but the studies are contradictory, and analyses using state-of-the art techniques for TL ... ...

    Abstract Obesity has negative effects on comorbidities, health-related quality of life and survival. Telomere length (TL) changes after bariatric surgery have been reported, but the studies are contradictory, and analyses using state-of-the art techniques for TL measurement, such as flow-FISH, are sparse. We measured TL dynamics via flow-FISH in patients undergoing bariatric surgery and compared their TL with 105 healthy individuals. Patients with obesity who underwent bariatric surgery were included. Lymphocyte and granulocyte absolute and age-adjusted (aa) TL were analyzed by flow-FISH before (preoperative cohort, n = 45) and after surgery (follow-up cohort, n = 35) at month 5.5 ± 3.9 (mean ± standard deviation [SD]). The initial lymphocyte aaTL was significantly shorter (-0.37 kb ± 0.18 kb, P = 0.045) in patients with obesity, while the granulocyte aaTL was not different from that in the healthy comparison population (0.28 kb ± 0.17 kb, P = 0.11). The telomere dynamics after surgery showed an increase in mean TL in both lymphocytes and granulocytes of patients with a pronounced BMI loss of ≥ 10 kg/m
    MeSH term(s) Humans ; Quality of Life ; Obesity/surgery ; Bariatric Surgery ; Telomere
    Language English
    Publishing date 2023-01-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-27196-6
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  7. Article: Insulin Resistance Is the Main Characteristic of Metabolically Unhealthy Obesity (MUO) Associated with NASH in Patients Undergoing Bariatric Surgery.

    Schmitz, Sophia M / Storms, Sebastian / Koch, Alexander / Stier, Christine / Kroh, Andreas / Rheinwalt, Karl P / Schipper, Sandra / Hamesch, Karim / Ulmer, Tom F / Neumann, Ulf P / Alizai, Patrick H

    Biomedicines

    2023  Volume 11, Issue 6

    Abstract: 1) Background: Metabolically healthy obesity (MHO) is a concept that applies to obese patients without any elements of metabolic syndrome (metS). In turn, metabolically unhealthy obesity (MUO) defines the presence of elements of metS in obese patients. ... ...

    Abstract (1) Background: Metabolically healthy obesity (MHO) is a concept that applies to obese patients without any elements of metabolic syndrome (metS). In turn, metabolically unhealthy obesity (MUO) defines the presence of elements of metS in obese patients. The components of MUO can be divided into subgroups regarding the elements of inflammation, lipid and glucose metabolism and cardiovascular disease. MUO patients appear to be at greater risk of developing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) compared to MHO patients. The aim of this study was to evaluate the influence of different MUO components on NAFLD and NASH in patients with morbid obesity undergoing bariatric surgery. (2) Methods: 141 patients undergoing bariatric surgery from September 2015 and October 2021 at RWTH Aachen university hospital (Germany) were included. Patients were evaluated pre-operatively for characteristics of metS and MUO (HbA1c, HOMA, CRP, BMI, fasting glucose, LDL, TG, HDL and the presence of arterial hypertension). Intraoperatively, a liver biopsy was taken from the left liver lobe and evaluated for the presence of NAFLD or NASH. In ordinal regression analyses, different factors were evaluated for their influence on NAFLD and NASH. (3) Results: Mean BMI of the patients was 52.3 kg/m
    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11061595
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  8. Article ; Online: Health-related quality of life outcomes following Roux-en-Y gastric bypass versus one anastomosis gastric bypass.

    Rheinwalt, Karl Peter / Fobbe, Anna / Plamper, Andreas / Alizai, Patrick Hamid / Schmitz, Sophia Marie-Therese / Brol, Maximilian Joseph / Trebicka, Jonel / Neumann, Ulf Peter / Ulmer, Tom Florian

    Langenbeck's archives of surgery

    2023  Volume 408, Issue 1, Page(s) 74

    Abstract: Purpose: Roux-en-Y gastric bypass (RYGB) and one anastomosis gastric bypass (OAGB) are effective standard bariatric surgeries with comparable weight loss and remission of obesity-related comorbidities. As procedure-specific health-related quality of ... ...

    Abstract Purpose: Roux-en-Y gastric bypass (RYGB) and one anastomosis gastric bypass (OAGB) are effective standard bariatric surgeries with comparable weight loss and remission of obesity-related comorbidities. As procedure-specific health-related quality of life (HrQoL) outcomes have not been directly compared thus far, we conducted this questionnaire-based study.
    Methods: Two hundred forty patients after undergoing either RYGB or OAGB between 2011 and 2016 were contacted and asked to fill out SF36 and BAROS questionnaires. All statistical analysis was performed with Microsoft Excel and GraphPad Prism. Primary objectives were procedure-dependent differences in HrQoL. Secondary objectives were weight loss and remission of comorbidities.
    Results: One hundred nineteen of 240 contacted patients (49.6%) replied, 58 after RYGB (48.7%) and 61 after OAGB (51.3%). Follow-up period was < 24 months in 52 and > 24 months in 64 evaluable patients. The mean age was 46 years (range 23 to 71). Regarding the < 24 months groups, both physical and psychological SF36 sum scales were comparably high. Only the subcategory "general health perception" was significantly better after RYGB. Significantly higher excess weight loss (EWL) after RYGB (88.81%) compared to OAGB (66.25%) caused significantly better global < 24 months BAROS outcomes, whereas remission of comorbidities and HrQoL was similar. Both > 24 months groups showed high SF36-HrQoL sum scales. Global mean BAROS results after > 24 months were "very good" in both procedures. EWL in RYGB (80.81%) and in OAGB (81.36%) were comparably excellent.
    Conclusion: Concerning SF36 and BAROS evaluated HrQoL in early and late postoperative phases, both procedures demonstrated comparable and relevant improvements. Further (preferably randomized) studies should include evaluation of preoperative HrQoL.
    MeSH term(s) Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Gastric Bypass/methods ; Obesity, Morbid/surgery ; Quality of Life ; Obesity/surgery ; Weight Loss ; Retrospective Studies ; Anastomosis, Roux-en-Y/methods
    Language English
    Publishing date 2023-02-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-02792-w
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  9. Article ; Online: Letter to the Editor: Bariatric Surgery and Endoluminal Procedures: IFSO Worldwide Survey 2014.

    Plamper, Andreas / Deitel, Mervyn / Rheinwalt, Karl P

    Obesity surgery

    2017  Volume 28, Issue 1, Page(s) 249–250

    MeSH term(s) Bariatric Surgery ; Gastric Bypass ; Humans ; Obesity, Morbid ; Surveys and Questionnaires
    Language English
    Publishing date 2017-10-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-017-2957-2
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  10. Article ; Online: Letter to the Editor: MGB and OAGB.

    Deitel, Mervyn / Kular, Kuldeepak Singh / Musella, Mario / Rheinwalt, Karl Peter

    Obesity surgery

    2018  Volume 28, Issue 8, Page(s) 2535–2536

    Language English
    Publishing date 2018-06-26
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-018-3327-4
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