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Book ; Online: CO2 Capture and Renewable Energy

González Plaza, Marta / Ribeiro, Rui P. P. L

2022

Keywords	History of engineering & technology ; zeolite ; ZSM-5 ; adsorption ; biogas upgrading ; shaping ; extrusion ; CO2 capture ; cement ; post-combustion ; absorption ; membranes ; calcium looping ; oxyfuel ; direct separation ; CO2 emissions ; CCS ; CCUS ; global facilities ; Zn(dcpa) ; MOF ; framework flexibility ; gas storage ; biogas ; carbon capture ; carbon footprint ; carbon capture and storage ; zero/low emission building ; greenhous effect ; environmental protection ; carbon capture (CC) ; carbon capture and storage (CCS) ; micro-combined heat and power (micro-CHP) ; micro-cogeneration ; energy systems ; buildings ; GHG emissions ; n/a
Language	English
Size	1 electronic resource (140 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030380226
ISBN	9783036549606 ; 3036549609
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: pyGOMoDo: GPCRs modeling and docking with python.

Ribeiro, Rui P / Giorgetti, A

Bioinformatics (Oxford, England)

2023 Volume 39, Issue 5

Abstract: Motivation: We present pyGOMoDo, a Python library to perform homology modeling and docking, specifically designed for human GPCRs. pyGOMoDo is a python wrap-up of the updated functionalities of GOMoDo web server (https://molsim.sci.univr.it/gomodo). It ... ...

Abstract	Motivation: We present pyGOMoDo, a Python library to perform homology modeling and docking, specifically designed for human GPCRs. pyGOMoDo is a python wrap-up of the updated functionalities of GOMoDo web server (https://molsim.sci.univr.it/gomodo). It was developed having in mind its usage through Jupyter notebooks, where users can create their own protocols of modeling and docking of GPCRs. In this article, we focus on the internal structure and general capabilities of pyGOMoDO and on how it can be useful for carrying out structural biology studies of GPCRs. Results: The source code is freely available at https://github.com/rribeiro-sci/pygomodo under the Apache 2.0 license. Tutorial notebooks containing minimal working examples can be found at https://github.com/rribeiro-sci/pygomodo/tree/main/examples.
MeSH term(s)	Humans ; Computational Biology/methods ; Software ; Molecular Dynamics Simulation ; Gene Library
Language	English
Publishing date	2023-05-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1422668-6
ISSN	1367-4811 ; 1367-4803
ISSN (online)	1367-4811
ISSN	1367-4803
DOI	10.1093/bioinformatics/btad294
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Article: Zieve's Syndrome: An Underdiagnosed Cause of Non-immune Hemolytic Anemia.

Ribeiro, Rui / Ferreira, Marli / Coelho, Rui / Pereira, Cláudia

Cureus

2024 Volume 16, Issue 1, Page(s) e52034

Abstract: Zieve's syndrome is an underdiagnosed condition characterized by the triad of jaundice, hemolytic anemia, and hyperlipidemia in the setting of chronic alcohol use. It may be accompanied by acute alcoholic hepatitis. The distinction between the ... ...

Abstract	Zieve's syndrome is an underdiagnosed condition characterized by the triad of jaundice, hemolytic anemia, and hyperlipidemia in the setting of chronic alcohol use. It may be accompanied by acute alcoholic hepatitis. The distinction between the coexistence of acute alcoholic hepatitis with Zieve's syndrome and Zieve's syndrome in isolation is crucial, given the different treatments and prognoses in these situations. A 35-year-old woman presented with complaints of abdominal discomfort, nausea, and vomiting in the previous week. She was a heavy drinker with resultant cirrhosis, splenomegaly, and esophageal varices. An ancillary test showed hemolytic anemia, moderately elevated transaminases, hyperbilirubinemia, and coagulopathy. A negative direct Coombs test established the anemia as non-immune, supporting the diagnosis of Zieve's syndrome despite the absence of hyperlipidemia. Maddrey's discriminant function score was 92 points, so she was treated with supportive measures, as well as corticosteroids in the setting of acute alcoholic hepatitis. The patient showed a favorable clinical and analytical evolution and was discharged home one month following admission with her hemoglobin levels stabilized. Previous literature focused on the distinction between Zieve's syndrome and acute alcoholic hepatitis but they may coexist.
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52034
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Article: A Case of Acute Eosinophilic Pneumonia Associated With Non-steroidal Anti-inflammatory Drugs.

Ribeiro, Rui / Teixeira, Andreia / Lopes, Tânia / Cruz, Célia

Cureus

2024 Volume 16, Issue 1, Page(s) e52159

Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and their gastric, cardiovascular, and renal adverse effects have been well documented. Although rare, NSAID-induced acute eosinophilic pneumonia (AEP) may occur. We report a case of AEP ... ...

Abstract	Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and their gastric, cardiovascular, and renal adverse effects have been well documented. Although rare, NSAID-induced acute eosinophilic pneumonia (AEP) may occur. We report a case of AEP related to naproxen and celecoxib. The patient presented with dry cough and breathlessness two weeks after she started taking these drugs. The chest radiograph displayed bilateral opacities and she had peripheral eosinophilia. Bronchoalveolar lavage was performed at a time when blood eosinophilia was already decreasing and cell analysis revealed 63700 cells/mL with 9% eosinophil. After ruling out other possible etiologies, drug-induced AEP was diagnosed. The patient improved after drug discontinuation. When it comes to drug-induced AEP identifying a causative agent is essential as cessation of the drug is the mainstay of the treatment.
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52159
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Article ; Online: Pre-exposure to seawater or chloride salts influences the avoidance-selection behavior of zebrafish larvae in a conductivity gradient

Venâncio, Cátia / Ribeiro, Rui / Lopes, Isabel

Environmental Pollution. 2023 Oct., v. 334 p.122126-

2023

Abstract: The risk assessment of freshwater salinization is constructed around standard assays and using sodium chloride (NaCl), neglecting that the stressor is most likely a complex mixture of ions and the possibility of prior contact with it, triggering ... ...

Abstract	The risk assessment of freshwater salinization is constructed around standard assays and using sodium chloride (NaCl), neglecting that the stressor is most likely a complex mixture of ions and the possibility of prior contact with it, triggering acclimation mechanisms in the freshwater biota. To date, as far as we are aware of, no information has been generated integrating both acclimation and avoidance behavior in the context of salinization, that may allow these risk assessments upgrading. Accordingly, 6-days-old Danio rerio larvae were selected to perform 12-h avoidance assays in a non-confined 6-compartment linear system to simulate conductivity gradients using seawater (SW) and the chloride salts MgCl₂, KCl, and CaCl₂. Salinity gradients were established from conductivities known to cause 50% egg mortality in a 96-h exposure (LC₅₀,₉₆ₕ,ₑₘbᵣyₒ). The triggering of acclimation processes, which could influence organisms’ avoidance-selection under the conductivity gradients, was also studied using larvae pre-exposed to lethal levels of each salt or SW. Median avoidance conductivities after a 12-h of exposure (AC₅₀,₁₂ₕ), and the Population Immediate Decline (PID) were computed. All non-pre-exposed larvae were able to detect and flee from conductivities corresponding to the LC₅₀,₉₆ₕ,ₑₘbᵣyₒ, selecting compartments with lower conductivities, except for KCl. The AC₅₀,₁₂ₕ and LC₅₀,₉₆ₕ overlapped for MgCl₂ and CaCl₂, though the former is considered as more sensitive as it was obtained in 12 h of exposure. The AC₅₀,₁₂ₕ for SW was 1.83-fold lower than the LC₅₀,₉₆ₕ, thus, reinforcing the higher sensitivity of the parameter ACₓ and its adequacy for risk assessment frameworks. The PID, at low conductivities, was solely explained by the avoidance behavior of non-pre-exposed larvae. Larvae pre-exposed to lethal levels of salt or SW were found to select higher conductivities, except for MgCl₂. Results indicated that avoidance-selection assays are ecologically relevant and sensitive tools to be used in risk assessment processes. Stressor pre-exposure influenced organisms’ avoidance-selection behavior under conductivity gradients, suggesting that under salinization events organisms may acclimate, remaining in altered habitats.
Keywords	Danio rerio ; acclimation ; avoidance behavior ; decline ; eggs ; freshwater ; mortality ; pollution ; risk ; risk assessment ; salinity ; seawater ; sodium chloride ; Avoidance ; Selection ; Habitat disruption ; Resilience ; Behavior ; Salinization
Language	English
Dates of publication	2023-10
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2023.122126
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Ecological risk assessment of the Paraíba River estuary (Brazil): Plan for a tier 1 screening phase for the ecotoxicological line of evidence

Cortez, Creuza S. / Ribeiro, Rui / Moreira-Santos, Matilde

Chemosphere. 2023 Sept., v. 335 p.139039-

2023

Abstract: The knowledge produced in temperate regions is still used today to evaluate environmental problems in the tropics, without taking into consideration environmental differences, such as local conditions, the sensitivity and ecology of species, and exposure ...

Abstract	The knowledge produced in temperate regions is still used today to evaluate environmental problems in the tropics, without taking into consideration environmental differences, such as local conditions, the sensitivity and ecology of species, and exposure routes of contaminants, essential for understanding and determining the fate and toxicity of chemicals. Considering that Environmental Risk Assessment (ERA) studies for tropical systems are scarce and need to be adjusted, the present study aims at contributing to the awareness and development of tropical ecotoxicology. The estuary of the Paraíba River in Northeast Brazil was selected as a model study-case, as it is a large estuary, subjected to a heavy human pressure due to the numerous social, economic and industrial activities. The present study describes the framework for the problem formulation phase of the ERA process; it first includes a detailed integration of the scientific information available on the study area, to then derive the conceptual model, and finally present the analysis plan for the tier 1 screening phase. The latter is designed to be fundamentally supported by the ecotoxicological line of evidence, to ascertain, without delay, where and why there are environmental problems (i.e., adverse biological effects); ecotoxicological tools developed in temperate climates will be optimized to assess water quality in a tropical system. In addition to its intrinsic value for protecting the study area, the results of the present study are expected to provide an important baseline for conducting ERA in similar tropical aquatic systems across the globe.
Keywords	ecology ; ecotoxicology ; environmental assessment ; estuaries ; humans ; models ; rivers ; toxicity ; water quality ; Brazil ; Tropical ecotoxicology ; Estuarine system ; Problem formulation ; Conceptual model ; Analysis plan ; Ecotoxicological tools
Language	English
Dates of publication	2023-09
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.139039
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Pre-exposure to seawater or chloride salts influences the avoidance-selection behavior of zebrafish larvae in a conductivity gradient.

Venâncio, Cátia / Ribeiro, Rui / Lopes, Isabel

Environmental pollution (Barking, Essex : 1987)

2023 Volume 334, Page(s) 122126

Abstract	The risk assessment of freshwater salinization is constructed around standard assays and using sodium chloride (NaCl), neglecting that the stressor is most likely a complex mixture of ions and the possibility of prior contact with it, triggering acclimation mechanisms in the freshwater biota. To date, as far as we are aware of, no information has been generated integrating both acclimation and avoidance behavior in the context of salinization, that may allow these risk assessments upgrading. Accordingly, 6-days-old Danio rerio larvae were selected to perform 12-h avoidance assays in a non-confined 6-compartment linear system to simulate conductivity gradients using seawater (SW) and the chloride salts MgCl
MeSH term(s)	Animals ; Chlorides/toxicity ; Zebrafish ; Salts ; Avoidance Learning ; Larva ; Calcium Chloride ; Sodium Chloride/toxicity ; Seawater ; Water Pollutants, Chemical/toxicity
Chemical Substances	Chlorides ; Salts ; Calcium Chloride (M4I0D6VV5M) ; Sodium Chloride (451W47IQ8X) ; Water Pollutants, Chemical
Language	English
Publishing date	2023-06-28
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2023.122126
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Article ; Online: Ecological risk assessment of the Paraíba River estuary (Brazil): Plan for a tier 1 screening phase for the ecotoxicological line of evidence.

Cortez, Creuza S / Ribeiro, Rui / Moreira-Santos, Matilde

Chemosphere

2023 Volume 335, Page(s) 139039

Abstract	The knowledge produced in temperate regions is still used today to evaluate environmental problems in the tropics, without taking into consideration environmental differences, such as local conditions, the sensitivity and ecology of species, and exposure routes of contaminants, essential for understanding and determining the fate and toxicity of chemicals. Considering that Environmental Risk Assessment (ERA) studies for tropical systems are scarce and need to be adjusted, the present study aims at contributing to the awareness and development of tropical ecotoxicology. The estuary of the Paraíba River in Northeast Brazil was selected as a model study-case, as it is a large estuary, subjected to a heavy human pressure due to the numerous social, economic and industrial activities. The present study describes the framework for the problem formulation phase of the ERA process; it first includes a detailed integration of the scientific information available on the study area, to then derive the conceptual model, and finally present the analysis plan for the tier 1 screening phase. The latter is designed to be fundamentally supported by the ecotoxicological line of evidence, to ascertain, without delay, where and why there are environmental problems (i.e., adverse biological effects); ecotoxicological tools developed in temperate climates will be optimized to assess water quality in a tropical system. In addition to its intrinsic value for protecting the study area, the results of the present study are expected to provide an important baseline for conducting ERA in similar tropical aquatic systems across the globe.
MeSH term(s)	Humans ; Ecotoxicology ; Estuaries ; Rivers ; Brazil ; Risk Assessment/methods ; Water Pollutants, Chemical/toxicity ; Environmental Monitoring/methods
Chemical Substances	Water Pollutants, Chemical
Language	English
Publishing date	2023-06-04
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.139039
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Article ; Online: One Anastomosis Transit Bipartition (OATB): Rational and Mid-term Outcomes.

Ribeiro, Rui / Viveiros, Octávio / Taranu, Viorel / Rossoni, Carina

Obesity surgery

2023 Volume 34, Issue 2, Page(s) 371–381

Abstract: Background: The "One-anastomosis transit bipartition" (OATB) is a promising emerging technique in the metabolic syndrome treatment.: Objective: To demonstrate the results achieved with OATB in the first 5 years after surgery.: Method: Cross- ... ...

Abstract	Background: The "One-anastomosis transit bipartition" (OATB) is a promising emerging technique in the metabolic syndrome treatment. Objective: To demonstrate the results achieved with OATB in the first 5 years after surgery. Method: Cross-sectional, retrospective study, with individuals undergoing primary OATB. Individuals included in the study were: ≥ 18 years, BMI ≥ 35 kg/m Results: Sixty eight participants, 75% women, average age 45.5 years and BMI 41 kg/m Conclusion: We conclude that OATB is a safe and effective technique, demonstrating good control of T2DM and metabolic syndrome. There is a requirement to treat previous nutritional deficits. We need more long-term evidence and comparison to other surgical techniques.
MeSH term(s)	Humans ; Female ; Middle Aged ; Male ; Obesity, Morbid/surgery ; Diabetes Mellitus, Type 2/surgery ; Diabetes Mellitus, Type 2/complications ; Metabolic Syndrome/complications ; Retrospective Studies ; Cross-Sectional Studies ; Gastrectomy/methods ; Nutrition Disorders ; Anastomosis, Surgical/methods
Language	English
Publishing date	2023-12-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-023-06988-3
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Article: Fosfomycin-Induced Liver Injury: A Case Report.

Ribeiro, Rui / Antas, Judite / Pais Monteiro, Ana / Magalhães, José / Miranda, Diana / Cruz, Célia

Cureus

2024 Volume 16, Issue 3, Page(s) e55508

Abstract: Fosfomycin is an antibiotic frequently used to treat uncomplicated urinary tract infections. It is normally well-tolerated, but there are some reports of clinically relevant liver injury. We present the case of a 73-year-old female who presented with ... ...

Abstract	Fosfomycin is an antibiotic frequently used to treat uncomplicated urinary tract infections. It is normally well-tolerated, but there are some reports of clinically relevant liver injury. We present the case of a 73-year-old female who presented with paucisymptomatic hepatocellular acute liver injury six days after taking fosfomycin. After ruling out viral, ischemic, and autoimmune hepatitis, as well as Wilson disease and biliary disorders, she was diagnosed with drug-induced liver injury (DILI) related to fosfomycin. The patient showed major improvement during the first week and the resolution of liver injury one month after onset. This case report aims to underscore the potential hepatotoxicity of fosfomycin.
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.55508
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