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  1. Article ; Online: Influência do modo de preparo de alimentos na prevenção da aterosclerose.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Revista da Associacao Medica Brasileira (1992)

    2013  Volume 59, Issue 2, Page(s) 148–154

    Abstract: Objective: To analyze the influence of food preparation methods on the composition of fatty acids and cholesterol in foods.: Methods: The chemical composition of cholesterol and fatty acids was analyzed in eight different types of meat and feijoada ... ...

    Title translation The influence of food preparation methods on atherosclerosis prevention.
    Abstract Objective: To analyze the influence of food preparation methods on the composition of fatty acids and cholesterol in foods.
    Methods: The chemical composition of cholesterol and fatty acids was analyzed in eight different types of meat and feijoada in relation to different methods of preparation.
    Results: Feijoada, when prepared with the beans and meats in separate pots, has less cholesterol (12.1 vs. 16.1mg, respectively, p=0.005) and saturated fat (1.4 vs. 1.9mg, p=0.046) than when it is prepared in a single pot. Broiled chicken without the skin has less saturated fat when compared with skinless fried chicken (1,505 vs. 7,645mg, p=0.049). Broiled shrimp also has a lower saturated fat content than fried shrimp (532 vs. 1,262mg, p=0.049). Broiled ribeye steak without fat has a lower cholesterol content when compared with the fried steak (102 vs. 114mg, p=0.049).
    Conclusion: The analysis indicates that the method of food preparation influences the fat content of foods, with potential impact on the prescription of low-fat and low-cholesterol diets.
    MeSH term(s) Animals ; Atherosclerosis/prevention & control ; Cholesterol/analysis ; Cooking/methods ; Dietary Fats/analysis ; Fabaceae ; Fatty Acids/chemistry ; Fishes ; Meat/analysis ; Penaeidae ; Poultry ; Swine
    Chemical Substances Dietary Fats ; Fatty Acids ; Cholesterol (97C5T2UQ7J)
    Language Portuguese
    Publishing date 2013-03
    Publishing country Brazil
    Document type English Abstract ; Journal Article
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1016/j.ramb.2012.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chemical food composition: implications for atherosclerosis prevention.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Revista da Associacao Medica Brasileira (1992)

    2011  Volume 57, Issue 2, Page(s) 153–157

    Abstract: Objective: To compare the fatty acid and cholesterol content in food acquired in Brazil with the composition found in the most frequently used reference tables in the country.: Methods: The fatty acid and cholesterol content in 41 food items ... ...

    Abstract Objective: To compare the fatty acid and cholesterol content in food acquired in Brazil with the composition found in the most frequently used reference tables in the country.
    Methods: The fatty acid and cholesterol content in 41 food items frequently used in our country and the various directions to prepare them were reviewed by using specific methodology and the information was compared to the tables adopted by Unicamp and UNIFESP.
    Results: According to Unicamp table, the cholesterol content found in parmesan cheese was 100.7 mg/100 g, while it was 68 mg/100 g in UNIFESP table, that is, a 48% (p < 0.05), higher content in the former. This study table found a cholesterol content 31% lower (94 mg/100 g vs. 123 mg/100 g, p < 0.05) for yellow cheese. For whole milk, we found a 52% difference regarding cholesterol content, while the difference for saturated fat ranged from 1.4 g/100 g in Unicamp table to 2.130 g/100 g in our study table (p < 0.05). For some food items, no statistically significant differences were found among the tables. However, when a 1,800-calorie diet was prescribed, the discrepancies among the tables and lack of information resulted in clinically relevant differences in dietary recommendations.
    Conclusion: There are important differences in food fat content between the fatty acid and cholesterol content formally analyzed and the content shown on commonly used tables, and this can compromise our recommendations on preventing atherosclerosis. One possible explanation for the differences would be the fact that the UNIFESP table is American in origin.
    MeSH term(s) Atherosclerosis/prevention & control ; Brazil ; Cholesterol/analysis ; Cross-Sectional Studies ; Fatty Acids/analysis ; Food Analysis ; Humans ; Nutritional Requirements ; Nutritive Value
    Chemical Substances Fatty Acids ; Cholesterol (97C5T2UQ7J)
    Language Portuguese
    Publishing date 2011-04-29
    Publishing country Brazil
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/s0104-42302011000200011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Fat content of dairy products, eggs, margarines and oils: implications for atherosclerosis.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Arquivos brasileiros de cardiologia

    2010  Volume 95, Issue 1, Page(s) 55–60

    Abstract: Background: For appropriate advising on a meal plan aimed at the prevention of ischemic heart disease, it is necessary to know the chemical composition of foods.: Objective: To analyze the composition of fats, fatty acids and cholesterol in some ... ...

    Abstract Background: For appropriate advising on a meal plan aimed at the prevention of ischemic heart disease, it is necessary to know the chemical composition of foods.
    Objective: To analyze the composition of fats, fatty acids and cholesterol in some Brazilian specimens of edible oils, butter, margarines, dairy products and eggs, using the limits of a diet to prevent coronary artery disease.
    Methods: We analyzed the composition of edible oils, butter, margarines, dairy products and eggs. The findings were used as recommended by the American Heart Association for a 1,800 calorie diet.
    Results: Comparing the edible oils, the canola oil was found to be the best.Among the milks, the skimmed milk is most advisable one, but no advantages were found over the semi-skimmed milk. For the eggs, no differences were found in the types of milk found in the market. For cheeses, the "minas" cheese had the lowest content of cholesterol and saturated fat. Comparing margarine and butter, the former was found to be better when trans fats do not exceed the recommended levels.
    Conclusion: The composition of foods used in Brazil indicates that diets designed to enable primary and secondary prevention of ischemic heart disease can prioritize the use of semi-skimmed milk, sunflower oil, margarines with low content of trans fats and "minas" cheese.
    MeSH term(s) Atherosclerosis/etiology ; Atherosclerosis/prevention & control ; Dairy Products/adverse effects ; Dairy Products/analysis ; Dietary Fats/analysis ; Eggs/analysis ; Humans ; Margarine/analysis ; Oils/analysis ; Risk Factors
    Chemical Substances Dietary Fats ; Oils ; Margarine (8029-82-1)
    Language Portuguese
    Publishing date 2010-06-25
    Publishing country Brazil
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2010005000074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gender, age, social level and cardiovascular risk factors: considerations on the Brazilian reality.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Arquivos brasileiros de cardiologia

    2009  Volume 93, Issue 3, Page(s) e54–6

    MeSH term(s) Adolescent ; Adult ; Age Factors ; Aged ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Child ; Female ; Humans ; Male ; Middle Aged ; Risk Factors ; Sex Factors ; Socioeconomic Factors ; Young Adult
    Language Spanish
    Publishing date 2009-12-04
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2009000900022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cholesterol and fats in Brazilian foods: implications for prevention of atherosclerosis.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Arquivos brasileiros de cardiologia

    2009  Volume 92, Issue 3, Page(s) 180–5, 184–9

    Abstract: Background: In order to perform food surveys and prescribe diets, food composition tables have to be consulted. However, these tables are limited to the description of fatty acids and cholesterol contents and do not provide information on the different ... ...

    Abstract Background: In order to perform food surveys and prescribe diets, food composition tables have to be consulted. However, these tables are limited to the description of fatty acids and cholesterol contents and do not provide information on the different preparation methods.
    Objective: Based on data derived from an extensive analysis of the chemical composition of Brazilian foods, we assessed the impact of certain types of foods on diets recommended for the prevention of coronary disease.
    Methods: The fatty acid and cholesterol composition of some types of foods and different preparation methods were analyzed. These results were used according to the recommendations of the American Heart Association for an 1,800 calorie diet.
    Results: Cholesterol found in 100g of eggs (400mg) or fried beef liver (453mg) exceeds the amount recommended for secondary prevention, and there is no difference in cholesterol content between factory-farmed eggs and free-range eggs. The eggs had an average of 400mg of cholesterol per 100g, thus exceeding the recommended amount of up to 300mg. Each egg has 50g on average; one egg can be consumed provided that not more than 100mg of cholesterol are consumed per day. As regards saturated fat, butter (55.2g), margarine (19.4g), tilsit cheese (20.4g), Brazilian Dutch Edam cheese (19.9g), yellow (16.8g) and fresh white cheese (15.5g) exceed the 14g recommended if 100g or more are consumed. The same is true for soy oil (17.5g) and corn oil (16.1g).
    Conclusion: Better knowledge on fat and cholesterol contents in foods allows the prescription of amounts not exceeding the recommended values for prevention, and this may result in better compliance to diets.
    MeSH term(s) Animals ; Atherosclerosis/prevention & control ; Brazil ; Butter/analysis ; Cattle ; Cholesterol/analysis ; Eggs/analysis ; Eggs/classification ; Energy Intake ; Fatty Acids/analysis ; Humans ; Meat/analysis ; Meat/classification ; Primary Prevention ; Reference Standards ; Secondary Prevention ; Swine
    Chemical Substances Fatty Acids ; Butter (8029-34-3) ; Cholesterol (97C5T2UQ7J)
    Language Spanish
    Publishing date 2009-02-10
    Publishing country Brazil
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2009000300005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: What the cardiologist should know about trans fats.

    Scherr, Carlos / Ribeiro, Jorge Pinto

    Arquivos brasileiros de cardiologia

    2008  Volume 90, Issue 1, Page(s) e4–7

    MeSH term(s) Cardiology/education ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Dietary Fats/adverse effects ; Dyslipidemias/prevention & control ; Humans ; Risk Factors ; Trans Fatty Acids/adverse effects ; Trans Fatty Acids/metabolism
    Chemical Substances Dietary Fats ; Trans Fatty Acids
    Language Portuguese
    Publishing date 2008-03-03
    Publishing country Brazil
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2008000100012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effects of vildagliptin compared with glibenclamide on glucose variability after a submaximal exercise test in patients with type 2 diabetes: study protocol for a randomized controlled trial, DIABEX VILDA.

    Fofonka, Aline / Ribeiro, Jorge Pinto / Casali, Karina Rabello / Schaan, Beatriz D

    Trials

    2014  Volume 15, Page(s) 424

    Abstract: Background: Cardiovascular disease, endothelial dysfunction, and oxidative stress are common complications among patients with type 2 diabetes (T2DM). In addition to the average blood glucose concentration, glycemic variability may be an important ... ...

    Abstract Background: Cardiovascular disease, endothelial dysfunction, and oxidative stress are common complications among patients with type 2 diabetes (T2DM). In addition to the average blood glucose concentration, glycemic variability may be an important factor for the development of chronic diabetes complications. Patients with T2DM are treated with various types of oral glucose-lowering drugs. Exercise is considered to benefit the health of both healthy and unhealthy individuals, which has been confirmed by a number of scientific research studies in which the participants' health improved. Our general aim in this study will be to evaluate glucose variability after submaximal exercise test in patients receiving treatment with either vildagliptin or glibenclamide. The specific aims of this study are to evaluate the oxidative stress, endothelial function, and metabolic and cardiovascular responses to exercise under treatment with vildagliptin or glibenclamide. All these responses are important in patients with T2DM.
    Methods/design: This study is a PROBE (Prospective, Randomized, Open-label, Blinded-Endpoint) design clinical trial. The estimated sample needed is 20 patients with T2DM. In addition to the routine treatment (metformin), patients will receive a second drug orally for 12 weeks: the METV group will receive metformin plus vildagliptin (50 mg twice daily), and the METG group will receive metformin plus glibenclamide (5 to 10 mg twice daily.). Before and after intervention, evaluation of glycemic variability, endothelial function, oxidative stress, and metabolic and cardiovascular response will be performed at rest, during and after a submaximal exercise test (30 minutes, with an intensity based at 10% under the heart rate at the second threshold).
    Discussion: In addition to drug treatment, exercise is recommended for treatment of glycemic control in patients with T2DM, especially for its beneficial effects on blood glucose and HbA1c. Few studies have determined the effects of the association between exercise and oral glucose-lowering drugs. The study will be conducted to assess the metabolic and cardiovascular responses at rest, and during and after submaximal exercise in patients receiving one of two oral glucose-lowering drugs (vildagliptin or glibenclamide).
    Trial registration: ClinicalTrials.gov Identifier: NCT01867502 study release date: May-17-2013.
    MeSH term(s) Adamantane/adverse effects ; Adamantane/analogs & derivatives ; Adamantane/therapeutic use ; Biomarkers/blood ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Brazil ; Clinical Protocols ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/physiopathology ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Exercise Test ; Glyburide/adverse effects ; Glyburide/therapeutic use ; Glycated Hemoglobin A/metabolism ; Hemodynamics/drug effects ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/therapeutic use ; Nitriles/adverse effects ; Nitriles/therapeutic use ; Oxidative Stress/drug effects ; Predictive Value of Tests ; Prospective Studies ; Pyrrolidines/adverse effects ; Pyrrolidines/therapeutic use ; Research Design ; Time Factors ; Treatment Outcome
    Chemical Substances Biomarkers ; Blood Glucose ; Dipeptidyl-Peptidase IV Inhibitors ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Nitriles ; Pyrrolidines ; hemoglobin A1c protein, human ; vildagliptin (I6B4B2U96P) ; Adamantane (PJY633525U) ; Glyburide (SX6K58TVWC)
    Language English
    Publishing date 2014-11-04
    Publishing country England
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1468-6708
    ISSN (online) 1745-6215 ; 1468-6694
    ISSN 1468-6708
    DOI 10.1186/1745-6215-15-424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cirurgia de revascularização miocárdica sem circulação extracorpórea

    Blacher Celso / Ribeiro Jorge Pinto

    Arquivos Brasileiros de Cardiologia, Vol 80, Iss 6, Pp 656-

    uma técnica em busca de evidências

    2003  Volume 662

    Keywords Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2003-01-01T00:00:00Z
    Publisher Sociedade Brasileira de Cardiologia - SBC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Dyslipidemia in HIV-infected individuals.

    Sprinz, Eduardo / Lazzaretti, Rosmeri Kuhmmer / Kuhmmer, Regina / Ribeiro, Jorge Pinto

    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

    2011  Volume 14, Issue 6, Page(s) 575–588

    Abstract: Metabolic complications continue to play a major role in the management of HIV infection. Dyslipidemia associated with HIV infection and with the use of combined antiretroviral therapy includes elevations in triglycerides, reduced high-density ... ...

    Abstract Metabolic complications continue to play a major role in the management of HIV infection. Dyslipidemia associated with HIV infection and with the use of combined antiretroviral therapy includes elevations in triglycerides, reduced high-density cholesterol, and variable increases in low-density and total cholesterol. The association between dyslipidemia and specific antiretroviral agents has been underscored. Multiple pathogenic mechanisms by which HIV and antiretroviral agents lead to dyslipidemia have been hypothesized, but they are still controversial. The potential clinical and pathological consequences of HIV-associated hyperlipidemia are not completely known, but several studies reported an increased risk of coronary artery disease in HIV-positive individuals receiving combined antiretroviral therapy. HIV-infected persons who have hyperlipidemia should be managed similarly to those without HIV infection in accordance with the National Cholesterol Education Program. Life style changes are the primary target. Statins and fibrates and/or modification in antiretroviral therapy are possible approaches to this problem.
    MeSH term(s) Anti-HIV Agents/adverse effects ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; Dyslipidemias/diagnosis ; Dyslipidemias/drug therapy ; Dyslipidemias/etiology ; HIV Infections/blood ; HIV Infections/drug therapy ; Humans ; Hypolipidemic Agents/therapeutic use ; Risk Factors
    Chemical Substances Anti-HIV Agents ; Hypolipidemic Agents
    Language English
    Publishing date 2011-02-03
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2041400-6
    ISSN 1678-4391 ; 1413-8670
    ISSN (online) 1678-4391
    ISSN 1413-8670
    DOI 10.1016/s1413-8670(10)70115-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Cirurgia de revascularização miocárdica sem circulação extracorpórea: uma técnica em busca de evidências.

    Blacher, Celso / Ribeiro, Jorge Pinto

    Arquivos brasileiros de cardiologia

    2003  Volume 80, Issue 6, Page(s) 656–662

    Title translation Coronary bypass without extracorporeal circulation. A technique in search of scientific evidence.
    MeSH term(s) Clinical Trials as Topic ; Cytokines ; Extracorporeal Circulation ; Humans ; Lymphocyte Activation ; Myocardial Revascularization/adverse effects ; Myocardial Revascularization/methods ; Systemic Inflammatory Response Syndrome/etiology
    Chemical Substances Cytokines
    Language Portuguese
    Publishing date 2003-07-02
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 0066-782X
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2003000600011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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