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Article ; Online: EXAMINE: targeting risk and treatment in diabetes.

Riche, Daniel M / Davis, Courtney

2015 Volume 386, Issue 10002, Page(s) 1443–1444

MeSH term(s)	Acute Coronary Syndrome/prevention & control ; Diabetes Mellitus, Type 2/prevention & control ; Diabetic Cardiomyopathies/prevention & control ; Female ; Heart Failure/chemically induced ; Humans ; Hypoglycemic Agents/adverse effects ; Male ; Piperidines/adverse effects ; Uracil/analogs & derivatives
Chemical Substances	Hypoglycemic Agents ; Piperidines ; Uracil (56HH86ZVCT)
Language	English
Publishing date	2015-10-10
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	3306-6
ISSN	1474-547X ; 0023-7507 ; 0140-6736
ISSN (online)	1474-547X
ISSN	0023-7507 ; 0140-6736
DOI	10.1016/S0140-6736(15)00406-7
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Article ; Online: Admission type is a paradoxical predictor of performance in problem-based learning courses.

Riche, Daniel M / Stover, Kayla R / Theilman, Gary D / Pittman, Joel R

Currents in pharmacy teaching & learning

2019 Volume 11, Issue 3, Page(s) 231–235

Abstract: Introduction: To determine if a difference in problem-based learning (PBL) performance or student attrition exists based on admission type.: Methods: This retrospective review analyzed admission type and student academic performance in the PBL course ...

Abstract	Introduction: To determine if a difference in problem-based learning (PBL) performance or student attrition exists based on admission type. Methods: This retrospective review analyzed admission type and student academic performance in the PBL course series from 2002 to 2009. Student scores were compiled based on admission type: provisional (high school), traditional with degree (bachelor's or higher), and traditional without degree (some college). ANOVA was performed on overall scores amongst the three admission types. Continuous data were analyzed using two-sided unpaired t-tests, and dichotomous data were analyzed using chi-square test. Results: 600 students received at least one score in the third-year (P3) PBL course series. 56% of students (n = 333) were admitted traditional without degree, while the remainder were split between provisional (n = 125) and traditional with degree (n = 142) admission. Provisionally admitted students had significantly higher scores than either of the other groups (p < 0.001 for both) and significantly fewer students failed a course versus either of the other groups (p < 0.001 for both). Additionally, traditional without degree students had significantly higher averages and fewer failing grades compared to traditional with degree students (p < 0.01 for both) over the eight years analyzed. Conclusions: This study's results suggest that degrees may not be predictive of success during PBL in the P3 year. Further work is needed in order to truly assess predictive nature of this and other factors among prospective pharmacy students.
MeSH term(s)	Analysis of Variance ; Chi-Square Distribution ; Educational Measurement/methods ; Educational Measurement/statistics & numerical data ; Humans ; Problem-Based Learning/methods ; Problem-Based Learning/standards ; Problem-Based Learning/statistics & numerical data ; Retrospective Studies ; School Admission Criteria ; Schools, Pharmacy/organization & administration ; Schools, Pharmacy/statistics & numerical data
Language	English
Publishing date	2019-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2515217-8
ISSN	1877-1300 ; 1877-1297
ISSN (online)	1877-1300
ISSN	1877-1297
DOI	10.1016/j.cptl.2018.12.003
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Article: Evidence-based review of statin use in patients with HIV on antiretroviral therapy.

Chastain, Daniel B / Stover, Kayla R / Riche, Daniel M

Journal of clinical & translational endocrinology

2017 Volume 8, Page(s) 6–14

Abstract: Introduction: As a result of improved safe and effective therapeutic options for human immunodeficiency virus (HIV), life expectancy of those living with HIV is increasing leading to new challenges (e.g., management of chronic diseases). Some chronic ... ...

Abstract	Introduction: As a result of improved safe and effective therapeutic options for human immunodeficiency virus (HIV), life expectancy of those living with HIV is increasing leading to new challenges (e.g., management of chronic diseases). Some chronic diseases (e.g., cardiovascular disease [CVD]), are up to two times more prevalent in patients with HIV. Statins are a mainstay of therapy for prevention of CVD; but, clinicians should be aware that not all statins are appropriate for use in the HIV population, especially those receiving antiretroviral therapy (ART). The purpose of this article is to review the pharmacokinetic and clinical data for statin therapy in HIV-infected patients receiving ART. Methods: A systematic literature search using PubMed and MEDLINE databases was performed using each statin drug name combined with HIV, pharmacokinetics, AIDS, and/or human immunodeficiency virus. English language trials published from 1946 to November 2016 were considered, and results were limited to clinical efficacy trials. Results: In general, atorvastatin and pravastatin are safe and effective for patients treated with protease-inhibitor (PI) or non-nucleoside reverse transcriptase inhibitor-based ART. Rosuvastatin is generally considered safe if started at a low dose, but should be avoided if possible in patients receiving PI-based ART. Pitavastatin has limited supporting evidence, but appears safe for use based on its pharmacokinetic properties and low number of drug interactions. Fluvastatin, lovastatin, and simvastatin should be avoided in patients receiving ART due to drug interactions, adverse events, and/or limited clinical data. Conclusion: Clinicians need to be familiar with the intricacies of statin selection for the prevention of CVD in patients with HIV on ART.
Language	English
Publishing date	2017-02-22
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2834222-7
ISSN	2214-6237
ISSN	2214-6237
DOI	10.1016/j.jcte.2017.01.004
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Article ; Online: Infectious complications of newer agents in the fight against diabetes.

Stover, Kayla R / Hugh, Emily / Sherman, Justin J / Malinowski, Scott S / Berdahl, Gideon J / Riche, Daniel M

The Nurse practitioner

2021 Volume 45, Issue 11, Page(s) 17–24

Abstract: Infectious complications have been reported with antidiabetic medications. Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors have been associated with upper respiratory tract infections and urinary tract infections. Sodium- ... ...

Abstract	Infectious complications have been reported with antidiabetic medications. Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors have been associated with upper respiratory tract infections and urinary tract infections. Sodium-glucose cotransporter 2 inhibitors have been associated with lower limb amputations, urinary tract infections, genital mycotic infections, and Fournier gangrene.
MeSH term(s)	Diabetes Mellitus/drug therapy ; Diabetes Mellitus/nursing ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Glucagon-Like Peptide-1 Receptor/agonists ; Humans ; Infections/chemically induced ; Randomized Controlled Trials as Topic ; Risk Assessment ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects
Chemical Substances	Dipeptidyl-Peptidase IV Inhibitors ; Glucagon-Like Peptide-1 Receptor ; Sodium-Glucose Transporter 2 Inhibitors
Language	English
Publishing date	2021-02-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604085-8
ISSN	1538-8662 ; 0361-1817
ISSN (online)	1538-8662
ISSN	0361-1817
DOI	10.1097/01.NPR.0000718508.65708.a1
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Article ; Online: Implications of ASHP's Phase II Match process.

Riche, Daniel M / Douglas, Kayla S / Sewell, Jeanna

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

2016 Volume 73, Issue 21, Page(s) 1720–1721

MeSH term(s)	Humans ; Pharmacy Residencies/methods ; Pharmacy Residencies/standards ; Societies, Pharmaceutical/standards
Language	English
Publishing date	2016-11-29
Publishing country	England
Document type	Letter
ZDB-ID	1224627-x
ISSN	1535-2900 ; 1079-2082
ISSN (online)	1535-2900
ISSN	1079-2082
DOI	10.2146/ajhp160314
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Article ; Online: Denosumab, a RANK ligand inhibitor, for postmenopausal women with osteoporosis.

Sutton, Emily E / Riche, Daniel M

The Annals of pharmacotherapy

2012 Volume 46, Issue 7-8, Page(s) 1000–1009

Abstract: Objective: To review the evidence for use of denosumab for the treatment of postmenopausal osteoporosis.: Data sources: A search of MEDLINE and EMBASE databases was conducted during January 2012, using the terms denosumab and osteoporosis, with index ...

Abstract	Objective: To review the evidence for use of denosumab for the treatment of postmenopausal osteoporosis. Data sources: A search of MEDLINE and EMBASE databases was conducted during January 2012, using the terms denosumab and osteoporosis, with index dates of 2000 to 2011. Additional information was gathered from Amgen and references cited in articles retrieved. Study selection and data extraction: English-language articles including clinical trials involving denosumab for treatment of osteoporosis and review articles were reviewed. Articles using denosumab in males or as treatment for conditions other than osteoporosis or osteopenia were excluded. Data synthesis: Many clinical trials have supported the safety and efficacy of denosumab in postmenopausal women with bone loss. It has been shown to improve bone mineral density, decrease markers of bone turnover, and prevent new vertebral fractures. It shows improvement over placebo in studies and has at least similar efficacy to alendronate in measurements of bone mineral density, with less risk for osteonecrosis of the jaw and atypical fracture, but with an increased risk of infections and neoplasms. European cost-effectiveness studies have also demonstrated that denosumab is a cost-effective choice compared to risedronate and no treatment for fracture prevention for postmenopausal women with osteoporosis. Conclusions: Denosumab has demonstrated efficacy and safety as a first-line treatment for postmenopausal osteoporosis in multiple clinical trials over at least 6 years. It may be most cost-effective for women who are unable or refuse to take bisphosphonate drugs.
MeSH term(s)	Antibodies, Monoclonal, Humanized/economics ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Cost-Benefit Analysis ; Denosumab ; Female ; Humans ; Osteoporosis, Postmenopausal/drug therapy ; RANK Ligand/antagonists & inhibitors
Chemical Substances	Antibodies, Monoclonal, Humanized ; RANK Ligand ; Denosumab (4EQZ6YO2HI)
Language	English
Publishing date	2012-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1101370-9
ISSN	1542-6270 ; 1060-0280
ISSN (online)	1542-6270
ISSN	1060-0280
DOI	10.1345/aph.1Q543
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Article: Sodium Glucose Transporter 2 Inhibitors and Diabetic Ketoacidosis in Three Patients with Diabetes: Underlying Causation.

Kelley, Jordan L / Strum, Matthew / Riche, Daniel M / Chandler, Andrew M

Journal of pharmacology & pharmacotherapeutics

2017 Volume 8, Issue 3, Page(s) 137–139

Abstract: Sodium glucose transporter 2 inhibitors (SGLT2i) inhibit the reabsorption of glucose in the renal tubules reducing glycemia and increasing glucosuria. The increased glucosuria causes a shift in normal flora and colonization of pathogenic microorganisms ... ...

Abstract	Sodium glucose transporter 2 inhibitors (SGLT2i) inhibit the reabsorption of glucose in the renal tubules reducing glycemia and increasing glucosuria. The increased glucosuria causes a shift in normal flora and colonization of pathogenic microorganisms leading to an increase in mycotic genital infections. Recent Food and Drug Administration reported cases of diabetic ketoacidosis (DKA) after initiation of SGLT2i probes the question of safety with such agents. The mechanisms of ketoacidosis and the breakdown of lipids are often misunderstood, and blame is placed on lack of insulin or on medications used to treat diabetes. However, many patients living with diabetes do not experience DKA if the proper treatment and management of concomitant comorbidities are addressed. After a retrospective chart review of 250 patients, three patients were identified with DKA while on SGLT2i, but for three distinct contrasting reasons. Assessment of the pharmacodynamics of SGLT2i and the pathophysiology of DKA infers that emphasis for prevention of SGLT2i-associated DKA should be placed on appropriate diagnosis, infection, and electrolyte abnormalities.
Language	English
Publishing date	2017-10-17
Publishing country	India
Document type	Journal Article
ZDB-ID	2593227-5
ISSN	0976-5018 ; 0976-500X
ISSN (online)	0976-5018
ISSN	0976-500X
DOI	10.4103/jpp.JPP_20_17
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Article ; Online: Frontline perspective on credentialing and privileging of ambulatory care pharmacists.

Weber, Zachary A / Skelley, Jessica W / Riche, Daniel M / Bryant Shilliday, Betsy / Cavanaugh, Jamie J / Foster, Keith

The International journal of pharmacy practice

2020 Volume 28, Issue 4, Page(s) 408–412

Abstract: Objectives: To present the current state of, and frontline advice on, the implementation of successful credentialing and privileging processes for practicing pharmacists in the United States.: Methods: The American Society of Health-System ... ...

Abstract	Objectives: To present the current state of, and frontline advice on, the implementation of successful credentialing and privileging processes for practicing pharmacists in the United States. Methods: The American Society of Health-System Pharmacists (ASHP) Section Advisory Group on Compensation and Practice Sustainability surveyed ambulatory care pharmacists via ASHP Connect about the status, structure and oversight of their ambulatory care clinical practice sites with credentialed and privileged (C&P) pharmacists. Key findings: Over 80% of survey respondents identified themselves as a C&P pharmacist, and over 90% indicated it is 'Important' or 'Very Important' for pharmacists to be C&P. Qualitative survey responses indicated the most important considerations for establishing or expanding a credentialing and privileging process for ambulatory care pharmacists were 'don't re-create the wheel', 'establish a physician champion and/or obtain leadership buy-in', 'be persistent and patient', 'develop a guidance document' and 'work within existing processes'. Conclusions: Starting a credentialing and privileging process is critical in preparation for, or response to, provider status recognition of pharmacists in the United States. When used with existing guidance documents on credentialing and privileging, 'front line' advice from practicing pharmacists can help promote expanded roles for pharmacists within healthcare systems.
MeSH term(s)	Ambulatory Care ; Credentialing ; Humans ; Medical Staff Privileges ; Pharmacists ; Pharmacy Service, Hospital
Language	English
Publishing date	2020-03-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1087040-4
ISSN	2042-7174 ; 0961-7671
ISSN (online)	2042-7174
ISSN	0961-7671
DOI	10.1111/ijpp.12619
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Article ; Online: Development of critical thinking in health professions education: A meta-analysis of longitudinal studies.

Reale, Matthew C / Riche, Daniel M / Witt, Benjamin A / Baker, William L / Peeters, Michael J

Currents in pharmacy teaching & learning

2018 Volume 10, Issue 7, Page(s) 826–833

Abstract: Introduction: While reports of critical thinking exist in the health professions literature, development of critical thinking across a broad range of health-professions students has not been systematically reviewed.: Methods: In this meta-analysis, ... ...

Abstract	Introduction: While reports of critical thinking exist in the health professions literature, development of critical thinking across a broad range of health-professions students has not been systematically reviewed. Methods: In this meta-analysis, multiple databases and journals were searched through February 2016 to identify longitudinal studies using standardized tests of critical thinking [California Critical Thinking Skills Test (CCTST), Health Science Reasoning Test (HSRT), and Defining Issues Test (DIT)] in any language. Two reviewers extracted information and collected information regarding primary author, publishing journal, health profession, critical thinking test, and time1/time2 means and standard deviations. Standardized mean differences (SMD) with 95% confidence intervals (CI) were reported using a random-effects model. Results: Four hundred sixty-two studies were screened, and 79 studies (representing 6884 students) were included. Studies contained 37 CCTST, 22 DIT, and 20 HSRT. Health professions comprised nursing, pharmacy, physical therapy, occupational therapy, dentistry, medicine, veterinary medicine, dental hygiene, clinical laboratory sciences, and allied health. Cohen's kappa was strong (0.82) for inter-reviewer agreement. Both the CCTST (SMD = 0.37, 95% CI = 0.23-0.52) and DIT (SMD = 0.28, 95%CI = 0.18-0.39) demonstrated significant increases in total scores, but the HSRT (SMD = 0.03, 95%CI = -0.05-0.12) did not show improvement. Discussion/conclusions: In this meta-analysis, students from the majority of health professions consistently showed improvement in development of critical thinking. In this diverse population, only the CCTST and DIT appeared responsive to change.
MeSH term(s)	Curriculum/standards ; Curriculum/trends ; Education/methods ; Education/trends ; Educational Measurement/methods ; Health Occupations/education ; Humans ; Longitudinal Studies ; Thinking
Language	English
Publishing date	2018-04-26
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2515217-8
ISSN	1877-1300 ; 1877-1297
ISSN (online)	1877-1300
ISSN	1877-1297
DOI	10.1016/j.cptl.2018.04.019
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Article ; Online: Transdermal testosterone replacement therapy in men.

Ullah, M Iftekhar / Riche, Daniel M / Koch, Christian A

Drug design, development and therapy

2014 Volume 8, Page(s) 101–112

Abstract: Androgen deficiency syndrome in men is a frequently diagnosed condition associated with clinical symptoms including fatigue, decreased libido, erectile dysfunction, and metabolic syndrome. Serum testosterone concentrations decline steadily with age. The ... ...

Abstract	Androgen deficiency syndrome in men is a frequently diagnosed condition associated with clinical symptoms including fatigue, decreased libido, erectile dysfunction, and metabolic syndrome. Serum testosterone concentrations decline steadily with age. The prevalence of androgen deficiency syndrome in men varies depending on the age group, known and unknown comorbidities, and the respective study group. Reported prevalence rates may be underestimated, as not every man with symptoms of androgen deficiency seeks treatment. Additionally, men reporting symptoms of androgen deficiency may not be correctly diagnosed due to the vagueness of the symptom quality. The treatment of androgen deficiency syndrome or male hypogonadism may sometimes be difficult due to various reasons. There is no consensus as to when to start treating a respective man or with regards to the best treatment option for an individual patient. There is also lack of familiarity with treatment options among general practitioners. The formulations currently available on the market are generally expensive and dose adjustment protocols for each differ. All these factors add to the complexity of testosterone replacement therapy. In this article we will discuss the general indications of transdermal testosterone replacement therapy, available formulations, dosage, application sites, and recommended titration schedule.
MeSH term(s)	Administration, Cutaneous ; Gels ; Hormone Replacement Therapy ; Humans ; Hypogonadism/diagnosis ; Male ; Testosterone/administration & dosage ; Testosterone/adverse effects ; Testosterone/physiology
Chemical Substances	Gels ; Testosterone (3XMK78S47O)
Language	English
Publishing date	2014-01-09
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2451346-5
ISSN	1177-8881 ; 1177-8881
ISSN (online)	1177-8881
ISSN	1177-8881
DOI	10.2147/DDDT.S43475
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