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  1. Article: SIMULATION TRAINING. COVID-19 Simulation Training: Resources for Healthcare Workers

    Richey, Stephen L.

    RT: Journal for Respiratory Care Practitioners

    Abstract: The article focuses on the novel coronavirus continue to increase across the U S , the need to train and educate frontline hospital staff to safely respond to medical emergencies with suspected or positive COVID-19 patients is more important than ever ... ...

    Abstract The article focuses on the novel coronavirus continue to increase across the U S , the need to train and educate frontline hospital staff to safely respond to medical emergencies with suspected or positive COVID-19 patients is more important than ever Topics inlcude the Society for Simulation in Healthcare has issued a statement supporting the use of virtual simulation as a replacement, and the clinical hours for medical students has enrolled in health sciences professions during COVID-19
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #830519
    Database COVID19

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  2. Article ; Online: Tourniquets for the control of traumatic hemorrhage: a review of the literature.

    Richey, Stephen L

    World journal of emergency surgery : WJES

    2007  Volume 2, Page(s) 28

    Language English
    Publishing date 2007-10-24
    Publishing country England
    Document type Journal Article
    ISSN 1749-7922
    ISSN (online) 1749-7922
    DOI 10.1186/1749-7922-2-28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Assessment and management of survivors of torture in the emergency department.

    Richey, Stephen L

    Journal of emergency nursing

    2007  Volume 33, Issue 5, Page(s) 484–487

    MeSH term(s) Cultural Diversity ; Emergency Nursing/methods ; Emergency Treatment/methods ; Emergency Treatment/nursing ; Humans ; Medical History Taking/methods ; Nurse's Role/psychology ; Nursing Assessment/methods ; Physical Examination/nursing ; Politics ; Refugees ; Residence Characteristics ; Survivors/psychology ; Torture/classification ; Torture/psychology
    Language English
    Publishing date 2007-08-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604632-0
    ISSN 0099-1767
    ISSN 0099-1767
    DOI 10.1016/j.jen.2007.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tourniquets for the control of traumatic hemorrhage

    Richey Stephen L

    World Journal of Emergency Surgery, Vol 2, Iss 1, p

    a review of the literature

    2007  Volume 28

    Keywords Surgery ; RD1-811 ; Medicine ; R ; DOAJ:Surgery ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2007-10-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Angiopoietins and non-vascular endothelial growth factor antiangiogenic targets in advanced renal cell carcinoma.

    Richey, Stephen L / Hutson, Thomas E

    Cancer journal (Sudbury, Mass.)

    2013  Volume 19, Issue 4, Page(s) 307–310

    Abstract: The treatment of metastatic renal cell carcinoma has evolved from an era dominated by immune modulation to an era of antiangiogenesis agents. Blockade of vascular endothelial growth factor-mediated pathways and mammalian target of rapamycin pathways has ... ...

    Abstract The treatment of metastatic renal cell carcinoma has evolved from an era dominated by immune modulation to an era of antiangiogenesis agents. Blockade of vascular endothelial growth factor-mediated pathways and mammalian target of rapamycin pathways has accounted for most of these gains. Although these agents have offered dramatic improvements in survival for kidney cancer patients, resistance inevitably occurs, and new classes of agents are needed to continue to improve outcomes in this setting. We discuss several alternative pathways of angiogenesis, which are being investigated as targets to overcome treatment resistance, including angiopoietin family proteins, fibroblast growth factor, platelet-derived growth factor, and vascular disrupting agents.
    MeSH term(s) Angiogenesis Inhibitors/genetics ; Angiogenesis Inhibitors/therapeutic use ; Angiopoietins/administration & dosage ; Carcinoma, Renal Cell/drug therapy ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Humans ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Protein Kinase Inhibitors/therapeutic use ; Vascular Endothelial Growth Factor A/genetics
    Chemical Substances Angiogenesis Inhibitors ; Angiopoietins ; Protein Kinase Inhibitors ; Vascular Endothelial Growth Factor A
    Language English
    Publishing date 2013-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0b013e31829d5d15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4470: Show issues Location:
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    Zs.MO 163: Show issues

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  6. Article ; Online: Metastatic extraosseous Ewing's sarcoma (EES)/primitive neuroectodermal tumor (PNET) of the kidney: 8-year durable response after induction and maintenance chemotherapy.

    Richey, Stephen L / Rao, Priya / Wood, Christopher G / Patel, Shreyaskumar / Tannir, Nizar M

    Clinical genitourinary cancer

    2012  Volume 10, Issue 3, Page(s) 210–212

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cisplatin/administration & dosage ; Doxorubicin/administration & dosage ; Etoposide/administration & dosage ; Humans ; Ifosfamide/administration & dosage ; Induction Chemotherapy ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/pathology ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/drug therapy ; Liver Neoplasms/secondary ; Lymphatic Metastasis ; Maintenance Chemotherapy ; Male ; Middle Aged ; Neuroectodermal Tumors, Primitive/diagnostic imaging ; Neuroectodermal Tumors, Primitive/drug therapy ; Neuroectodermal Tumors, Primitive/secondary ; Radiography ; Sarcoma, Ewing/diagnostic imaging ; Sarcoma, Ewing/drug therapy ; Sarcoma, Ewing/secondary ; Treatment Outcome ; Vincristine/administration & dosage
    Chemical Substances Vincristine (5J49Q6B70F) ; Etoposide (6PLQ3CP4P3) ; Doxorubicin (80168379AG) ; Cisplatin (Q20Q21Q62J) ; Ifosfamide (UM20QQM95Y)
    Language English
    Publishing date 2012-04-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2225121-2
    ISSN 1938-0682 ; 1558-7673
    ISSN (online) 1938-0682
    ISSN 1558-7673
    DOI 10.1016/j.clgc.2012.03.004
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  7. Article ; Online: Durable remission of metastatic renal cell carcinoma with gemcitabine and capecitabine after failure of targeted therapy.

    Richey, Stephen L / Ng, Chaan / Lim, Zita D / Jonasch, Eric / Tannir, Nizar M

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2010  Volume 29, Issue 8, Page(s) e203–5

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Capecitabine ; Carcinoma, Renal Cell/drug therapy ; Carcinoma, Renal Cell/enzymology ; Carcinoma, Renal Cell/secondary ; Deoxycytidine/administration & dosage ; Deoxycytidine/analogs & derivatives ; Fluorouracil/administration & dosage ; Fluorouracil/analogs & derivatives ; Humans ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/enzymology ; Kidney Neoplasms/pathology ; Male ; Middle Aged ; Molecular Targeted Therapy ; Protein Kinase Inhibitors/therapeutic use ; Remission Induction ; Time Factors ; Tomography, X-Ray Computed ; Treatment Failure ; Gemcitabine
    Chemical Substances Protein Kinase Inhibitors ; Deoxycytidine (0W860991D6) ; Capecitabine (6804DJ8Z9U) ; Fluorouracil (U3P01618RT) ; Gemcitabine
    Language English
    Publishing date 2010-12-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2010.31.6091
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    Zs.A 1847: Show issues Location:
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    Zs.MO 650: Show issues

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  8. Article ; Online: Phase II trial of pemetrexed plus gemcitabine in patients with locally advanced and metastatic nonclear cell renal cell carcinoma.

    Richey, Stephen L / Tamboli, Pheroze / Ng, Chaan S / Lin, E / Lim, Zita D / Araujo, John C / Jonasch, Eric / Sharma, Padmanee / Pagliaro, Lance C / Tannir, Nizar M

    American journal of clinical oncology

    2012  Volume 36, Issue 5, Page(s) 450–454

    Abstract: Objective: To determine the clinical activity and safety of the combination of pemetrexed and gemcitabine in advanced nonclear cell renal cell carcinoma (nccRCC).: Methods: In this phase II study, patients received pemetrexed 500 mg/m intravenous ... ...

    Abstract Objective: To determine the clinical activity and safety of the combination of pemetrexed and gemcitabine in advanced nonclear cell renal cell carcinoma (nccRCC).
    Methods: In this phase II study, patients received pemetrexed 500 mg/m intravenous infusion over 10 minutes on day 1 followed immediately by gemcitabine 1500 mg/m intravenously over 30 minutes on day 1, with cycles repeated every 14 days. Planned enrollment was 40 patients. The primary endpoints were objective response rate and progression-free survival (PFS). The secondary endpoints were safety and overall survival.
    Results: Between December 2005 and December 2008, 16 patients with locally advanced or metastatic nccRCC were enrolled. The trial was stopped early due to low efficacy and excessive toxicity. The objective response rate was 0% [95% confidence interval (CI), 0%-18%]. The median number of cycles administered was 4 (range, 1 to 12). Median PFS was 3.2 months (95% CI, 1.9-6+), and the 16-week PFS rate was 46.7% (95% CI, 19.8%-100%). Median overall survival was 23.2 months (95% CI, 12.9-38.1). The most common grade 3 or 4 adverse events were neutropenia (53%), leukopenia (53%), anemia (13%), fatigue (40%), and renal insufficiency (13%).
    Conclusions: In this phase II trial in nccRCC, the combination of pemetrexed and gemcitabine was toxic and ineffective. Further development of this regimen in nccRCC is not warranted.
    MeSH term(s) Adolescent ; Adrenal Gland Neoplasms/drug therapy ; Adrenal Gland Neoplasms/mortality ; Adrenal Gland Neoplasms/secondary ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bone Neoplasms/drug therapy ; Bone Neoplasms/mortality ; Bone Neoplasms/secondary ; Carcinoma, Renal Cell/drug therapy ; Carcinoma, Renal Cell/mortality ; Carcinoma, Renal Cell/secondary ; Deoxycytidine/administration & dosage ; Deoxycytidine/analogs & derivatives ; Female ; Follow-Up Studies ; Glutamates/administration & dosage ; Guanine/administration & dosage ; Guanine/analogs & derivatives ; Humans ; Infusions, Intravenous ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/mortality ; Kidney Neoplasms/pathology ; Liver Neoplasms/drug therapy ; Liver Neoplasms/mortality ; Liver Neoplasms/secondary ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Lung Neoplasms/secondary ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/mortality ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Pemetrexed ; Prognosis ; Survival Rate ; Young Adult
    Chemical Substances Glutamates ; Pemetrexed (04Q9AIZ7NO) ; Deoxycytidine (0W860991D6) ; Guanine (5Z93L87A1R) ; gemcitabine (B76N6SBZ8R)
    Language English
    Publishing date 2012-06-15
    Publishing country United States
    Document type Clinical Trial, Phase II ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604536-4
    ISSN 1537-453X ; 0277-3732
    ISSN (online) 1537-453X
    ISSN 0277-3732
    DOI 10.1097/COC.0b013e3182546a91
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1557: Show issues Location:
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  9. Article: Development and validation of a multiplexed Y-chromosome STR genotyping system, Y-PLEX 6, for forensic casework.

    Sinha, Sudhir K / Budowle, Bruce / Arcot, Santosh S / Richey, Stephen L / Chakrabor, Ranajit / Jones, Mary D / Wojtkiewicz, Patrick W / Schoenbauer, Dolores A / Gross, Ann Marie / Sinha, Siddhartha K / Shewale, Jaiprakash G

    Journal of forensic sciences

    2003  Volume 48, Issue 1, Page(s) 93–103

    Abstract: A Y-chromosome multiplex polymerase chain reaction (PCR) amplification kit, known as Y-PLEX 6, has been developed for use in human identification. The Y-PLEX 6 kit enables simultaneous amplification of six polymorphic short tandem repeat (STR) loci ... ...

    Abstract A Y-chromosome multiplex polymerase chain reaction (PCR) amplification kit, known as Y-PLEX 6, has been developed for use in human identification. The Y-PLEX 6 kit enables simultaneous amplification of six polymorphic short tandem repeat (STR) loci located on the non-recombinant region of the human Y-chromosome. These loci are: DYS393, DYS19, DYS38911, DYS390, DYS391, and DYS385. Our studies show that as little as 0.2 ng of template DNA can be used for analysis. The specificity of the amplification reaction enabled analysis of male DNA in a male:female DNA mixture at a ratio of 1:125. Among the six Y-STR loci, the maximum mean stutter percentage was 11.9 for allele at DYS38911 locus. Attempts at amplification of DNA from various animal sources revealed that the Y-PLEX 6 primers are human specific. Details of the development of the kit, generation and description of the allelic ladders, and validation of the multiplex PCR are presented. In addition, Y-STR allele and haplotype frequencies in three populations have been investigated. The data indicate that results obtained using the Y-PLEX 6 kit are robust, sensitive, and reliable and can be used in human forensic and male lineage identification cases.
    MeSH term(s) Animals ; Continental Population Groups/genetics ; DNA Fingerprinting/methods ; Female ; Forensic Medicine/methods ; Genetics, Population ; Genotype ; Haplotypes ; Humans ; Male ; Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; Sex Determination Processes ; Tandem Repeat Sequences ; Y Chromosome
    Language English
    Publishing date 2003-01
    Publishing country United States
    Document type Journal Article ; Validation Studies
    ZDB-ID 219216-0
    ISSN 1556-4029 ; 0022-1198
    ISSN (online) 1556-4029
    ISSN 0022-1198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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