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  1. AU="Riederer, Cordula"
  2. AU="Bao, Qi"
  3. AU="Tsang, Stephen H"
  4. AU="Isaranuwatchai, Wanrudee" AU="Isaranuwatchai, Wanrudee"
  5. AU="Goldring, Mary B"
  6. AU="Durrington, Charlotte"
  7. AU="Metka, M."
  8. AU="González Villarroel, Paula"
  9. AU="Gakuya, F."
  10. AU="Belloni-Fortina, Anna"
  11. AU="Teufel, Frank"

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  1. Artikel ; Online: Prescription of Opioid Analgesics for Chronic Non-Cancer Pain in Germany despite Contraindications: Administrative Claims Data Analysis.

    Niemann, Anja / Schrader, Nils F / Speckemeier, Christian / Abels, Carina / Blase, Nikola / Weitzel, Milena / Neumann, Anja / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen / Neusser, Silke

    International journal of environmental research and public health

    2024  Band 21, Heft 2

    Abstract: In Germany, long-term opioid treatment (L-TOT) for chronic non-tumor pain (CNTP) is discussed as not being performed according to the German guideline on L-TOT for CNTP. In the present analysis, the occurrence and predictors of inappropriate care/overuse ...

    Abstract In Germany, long-term opioid treatment (L-TOT) for chronic non-tumor pain (CNTP) is discussed as not being performed according to the German guideline on L-TOT for CNTP. In the present analysis, the occurrence and predictors of inappropriate care/overuse in a cohort of German insureds with L-TOT for CNTP by the presence of a contraindication with concurrent opioid analgesic (OA) therapy were investigated. We also analyzed whether prescribing physicians themselves diagnosed a contraindication. The retrospective cohort study was based on administrative claims data from a German statutory health insurance. Eight contraindication groups were defined based on the German guideline. Logistic regressions were performed in order to identify predictors for OA prescriptions despite contraindications. The possible knowledge of the prescribing physician about the contraindication was approximated by analyzing concordant unique physician identification numbers of OA prescriptions and contraindication diagnoses. A total of 113,476 individuals (75% female) with a mean age of 72 years were included. The most common documented contraindications were primary headaches (8.7%), severe mood disorders (7.7%) and pain in somatoform disorders (4.5%). The logistic regressions identified a younger age, longer history of OA therapy, opioid related psychological problems, and outpatient psychosomatic primary care as positive predictors for all contraindication groups.
    Mesh-Begriff(e) Humans ; Female ; Aged ; Male ; Analgesics, Opioid/therapeutic use ; Chronic Pain/drug therapy ; Retrospective Studies ; Analgesics ; Prescriptions ; Germany/epidemiology ; Neoplasms ; Data Analysis ; Practice Patterns, Physicians'
    Chemische Substanzen Analgesics, Opioid ; Analgesics
    Sprache Englisch
    Erscheinungsdatum 2024-02-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph21020180
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study.

    Hillerich, Vivienne / Valbert, Frederik / Neusser, Silke / Pfaar, Oliver / Klimek, Ludger / Sperl, Annette / Werfel, Thomas / Hamelmann, Eckard / Riederer, Cordula / Wobbe-Ribinski, Stefanie / Neumann, Anja / Wasem, Jürgen / Biermann-Stallwitz, Janine

    The European journal of health economics : HEPAC : health economics in prevention and care

    2023  

    Abstract: Background: Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality of Life (HRQoL) of the patients in order to identify ... ...

    Abstract Background: Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality of Life (HRQoL) of the patients in order to identify statistically significant influencing factors that determine HRQoL. Another aim was to assess and analyze data on cost-of-illness from a statutory health insurance perspective.
    Methods:  The EQ-5D-5L was used to evaluate the patients' HRQoL. To identify the factors influencing the HRQoL, a multinomial logistic regression analysis was conducted using groups based on the EQ-5D-5L index value as dependent variable. Routine data were analyzed to determine total healthcare costs.
    Results:  The average EQ-5D-5L index was 0.85 (SD 0.20). A high age, the amount of disease costs, low internal health-related control beliefs and high ozone exposure in the residential area were found to be statistically significant influencing factors for a low HRQoL, whereas low age, male sex and a good possibility to avoid the allergens were found to be statistically significant factors influencing a high HRQoL. On average, the study participants incurred annual costs of €3072 (SD: 3485), of which €699 (SD: 743) could be assigned to allergic respiratory diseases.
    Conclusions:  Overall, the patients in the VerSITA study showed a high level of HRQoL. The identified influencing factors can be used as starting points for improving the HRQoL of patients with allergic respiratory diseases. From the perspective of a statutory health insurance, per person expenditures for allergic respiratory diseases are rather low.
    Sprache Englisch
    Erscheinungsdatum 2023-07-07
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2045253-6
    ISSN 1618-7601 ; 1618-7598
    ISSN (online) 1618-7601
    ISSN 1618-7598
    DOI 10.1007/s10198-023-01598-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Care with allergen immunotherapy for allergic respiratory diseases in Germany-Predictors and deficits.

    Valbert, Frederik / Neusser, Silke / Pfaar, Oliver / Klimek, Ludger / Sperl, Annette / Werfel, Thomas / Hamelmann, Eckard / Riederer, Cordula / Wobbe-Ribinski, Stefanie / Hillerich, Vivienne / Neumann, Anja / Wasem, Jürgen / Biermann-Stallwitz, Janine

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

    2022  Band 52, Heft 12, Seite(n) 1422–1431

    Abstract: Background: Allergen immunotherapy (AIT) represents the only possibility of causal therapy for allergic respiratory diseases. Although the prevailing high prevalence of allergic diseases and restrictions in the daily lives of patients, AIT is offered to ...

    Abstract Background: Allergen immunotherapy (AIT) represents the only possibility of causal therapy for allergic respiratory diseases. Although the prevailing high prevalence of allergic diseases and restrictions in the daily lives of patients, AIT is offered to a suboptimal number of patients in Germany.
    Methods: Insured patients with documented allergic respiratory disease of one of the largest statutory health insurances in Germany, 'DAK-Gesundheit', were contacted by postal mail and asked to participate in the study. In case of written consent, primary and secondary data of patients were collected and analysed. Patient characteristics, predictors of being offered AIT, predictors of performing AIT and guideline-compliant care were analysed.
    Results: 2505 subjects were included in the VerSITA study. Allergy to tree pollen and native speaking were identified as predictors, which increase the probability of being offered AIT. The probability was significantly decreased by the characteristics allergic rhinitis only, allergic asthma only, age in years, non-German citizenship, no graduation and lower secondary qualification. Significant positive predictors for an AIT to be actually performed were: Allergy to tree pollen and male sex. Predictors that decrease the likelihood that AIT is performed were: only allergic asthma, current smoker, former smoker, age and non-German citizenship. Furthermore, it was possible to identify characteristics in which guideline-compliant patients differed significantly from the rest of the study population.
    Conclusions: Based on statutory health insurance data and patient survey data, the VerSITA study provides a broad and in-depth overview of the care situation with regard to AIT in Germany and identifies deficits.
    Mesh-Begriff(e) Humans ; Desensitization, Immunologic ; Rhinitis, Allergic/epidemiology ; Rhinitis, Allergic/therapy ; Pollen ; Asthma ; Germany/epidemiology ; Allergens
    Chemische Substanzen Allergens
    Sprache Englisch
    Erscheinungsdatum 2022-05-18
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645204-8
    ISSN 1365-2222 ; 0954-7894 ; 0960-2178
    ISSN (online) 1365-2222
    ISSN 0954-7894 ; 0960-2178
    DOI 10.1111/cea.14172
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Konferenzbeitrag: Opioid-Monotherapie bei chronischen nicht-tumorbedingten Schmerzen? Routinedatenanalyse weiterführender Therapiemaßnahmen bei Langzeitpatienten

    Schrader, Nils Frederik / Niemann, Anja / Speckemeier, Christian / Abels, Carina / Blase, Nikola / Giebel, Godwin / Weitzel, Milena / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen / Neusser, Silke

    Das Gesundheitswesen

    2023  Band 85, Heft 08/09

    Veranstaltung/Kongress Gemeinsame Jahrestagung der Deutschen Gesellschaft für Sozialmedizin und Prävention e.V. (DGSMP)*, des Deutschen Netzwerks Gesundheitskompetenz e. V. (DNGK) und des Nationalen Aktionsplans Gesundheitskompetenz (NAP), Hannover, 2023-08-30
    Sprache Deutsch
    Erscheinungsdatum 2023-08-01
    Verlag Georg Thieme Verlag
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0043-1770534
    Datenquelle Thieme Verlag

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  5. Artikel ; Konferenzbeitrag: Behandlung von chronischen nicht-tumorbedingten Schmerzen mit opioiden Analgetika: Evaluation der Versorgungsqualität mittels Patientenbefragung

    Niemann, Anja / Schrader, Nils Frederik / Speckemeier, Christian / Abels, Carina / Blase, Nikola / Giebel, Godwin / Weitzel, Milena / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen / Neusser, Silke

    Das Gesundheitswesen

    2023  Band 85, Heft 08/09

    Veranstaltung/Kongress Gemeinsame Jahrestagung der Deutschen Gesellschaft für Sozialmedizin und Prävention e.V. (DGSMP)*, des Deutschen Netzwerks Gesundheitskompetenz e. V. (DNGK) und des Nationalen Aktionsplans Gesundheitskompetenz (NAP), Hannover, 2023-08-30
    Sprache Deutsch
    Erscheinungsdatum 2023-08-01
    Verlag Georg Thieme Verlag
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0043-1770549
    Datenquelle Thieme Verlag

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  6. Artikel ; Konferenzbeitrag: Langzeitanwendung opioidhaltiger Analgetika in der Versorgung von Menschen mit Arthrose- und/oder Rückenschmerzen. Ergebnisse einer Patientenbefragung.

    Neusser, Silke / Niemann, Anja / Schrader, Nils Frederik / Speckemeier, Christian / Blase, Nikola / Weitzel, Milena / Abels, Carina / Giebel, Godwin / Riederer, Cordula / Straßmeir, Wolfgang / Nadstawek, Joachim / Wasem, Jürgen

    Das Gesundheitswesen

    2023  Band 85, Heft 08/09

    Veranstaltung/Kongress Gemeinsame Jahrestagung der Deutschen Gesellschaft für Sozialmedizin und Prävention e.V. (DGSMP)*, des Deutschen Netzwerks Gesundheitskompetenz e. V. (DNGK) und des Nationalen Aktionsplans Gesundheitskompetenz (NAP), Hannover, 2023-08-30
    Sprache Deutsch
    Erscheinungsdatum 2023-08-01
    Verlag Georg Thieme Verlag
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0043-1770686
    Datenquelle Thieme Verlag

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  7. Konferenzbeitrag: Behandlung von chronischen nicht-tumorbedingten Schmerzen mit opioiden Analgetika: Evaluation der Versorgungsqualität mittels Patientenbefragung

    Niemann, Anja / Schrader, Nils Frederik / Speckemeier, Christian / Abels, Carina / Blase, Nikola / Giebel, Godwin / Weitzel, Milena / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen / Neusser, Silke

    2023  , Seite(n) 23dkvf378

    Veranstaltung/Kongress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Schlagwörter Medizin, Gesundheit
    Erscheinungsdatum 2023-10-02
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/23dkvf378
    Datenquelle German Medical Science

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  8. Konferenzbeitrag: Langzeitanwendung opioidhaltiger Analgetika in der Versorgung von Menschen mit Arthrose- und/oder Rückenschmerzen. Ergebnisse einer Patientenbefragung

    Neusser, Silke / Niemann, Anja / Schrader, Nils Frederik / Blase, Nikola / Abels, Carina / Weitzel, Milena / Giebel, Godwin / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen

    2023  , Seite(n) 23dkvf305

    Veranstaltung/Kongress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Schlagwörter Medizin, Gesundheit
    Erscheinungsdatum 2023-10-02
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/23dkvf305
    Datenquelle German Medical Science

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  9. Konferenzbeitrag: Opioid-Monotherapie bei chronischen nicht-tumorbedingten Schmerzen? Routinedatenanalyse weiterführender Therapiemaßnahmen bei Langzeitpatienten

    Schrader, Nils Frederik / Niemann, Anja / Speckemeier, Christian / Abels, Carina / Blase, Nikola / Giebel, Godwin / Weitzel, Milena / Riederer, Cordula / Nadstawek, Joachim / Straßmeir, Wolfgang / Wasem, Jürgen / Neusser, Silke

    2023  , Seite(n) 23dkvf304

    Veranstaltung/Kongress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Schlagwörter Medizin, Gesundheit
    Erscheinungsdatum 2023-10-02
    Verlag German Medical Science GMS Publishing House; Düsseldorf
    Dokumenttyp Konferenzbeitrag
    DOI 10.3205/23dkvf304
    Datenquelle German Medical Science

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  10. Artikel ; Online: Incident autoimmune diseases in association with SARS-CoV-2 infection: a matched cohort study.

    Tesch, Falko / Ehm, Franz / Vivirito, Annika / Wende, Danny / Batram, Manuel / Loser, Friedrich / Menzer, Simone / Jacob, Josephine / Roessler, Martin / Seifert, Martin / Kind, Barbara / König, Christina / Schulte, Claudia / Buschmann, Tilo / Hertle, Dagmar / Ballesteros, Pedro / Baßler, Stefan / Bertele, Barbara / Bitterer, Thomas /
    Riederer, Cordula / Sobik, Franziska / Reitzle, Lukas / Scheidt-Nave, Christa / Schmitt, Jochen

    Clinical rheumatology

    2023  Band 42, Heft 10, Seite(n) 2905–2914

    Abstract: Objectives: To investigate whether the risk of developing an incident autoimmune disease is increased in patients with prior COVID-19 disease compared to those without COVID-19, a large cohort study was conducted.: Method: A cohort was selected from ... ...

    Abstract Objectives: To investigate whether the risk of developing an incident autoimmune disease is increased in patients with prior COVID-19 disease compared to those without COVID-19, a large cohort study was conducted.
    Method: A cohort was selected from German routine health care data. Based on documented diagnoses, we identified individuals with polymerase chain reaction (PCR)-confirmed COVID-19 through December 31, 2020. Patients were matched 1:3 to control patients without COVID-19. Both groups were followed up until June 30, 2021. We used the four quarters preceding the index date until the end of follow-up to analyze the onset of autoimmune diseases during the post-acute period. Incidence rates (IR) per 1000 person-years were calculated for each outcome and patient group. Poisson models were deployed to estimate the incidence rate ratios (IRRs) of developing an autoimmune disease conditional on a preceding diagnosis of COVID-19.
    Results: In total, 641,704 patients with COVID-19 were included. Comparing the incidence rates in the COVID-19 (IR=15.05, 95% CI: 14.69-15.42) and matched control groups (IR=10.55, 95% CI: 10.25-10.86), we found a 42.63% higher likelihood of acquiring autoimmunity for patients who had suffered from COVID-19. This estimate was similar for common autoimmune diseases, such as Hashimoto thyroiditis, rheumatoid arthritis, or Sjögren syndrome. The highest IRR was observed for autoimmune diseases of the vasculitis group. Patients with a more severe course of COVID-19 were at a greater risk for incident autoimmune disease.
    Conclusions: SARS-CoV-2 infection is associated with an increased risk of developing new-onset autoimmune diseases after the acute phase of infection. Key Points • In the 3 to 15 months after acute infection, patients who had suffered from COVID-19 had a 43% (95% CI: 37-48%) higher likelihood of developing a first-onset autoimmune disease, meaning an absolute increase in incidence of 4.50 per 1000 person-years over the control group. • COVID-19 showed the strongest association with vascular autoimmune diseases.
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; Cohort Studies ; Autoimmune Diseases/complications ; Autoimmune Diseases/epidemiology ; Arthritis, Rheumatoid
    Sprache Englisch
    Erscheinungsdatum 2023-06-19
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-023-06670-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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