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  1. AU="Riemann, Burkhard"
  2. AU="Nazir, Ahsan"
  3. AU="Kawakita, Emi"
  4. AU="Wang, Junnian"
  5. AU="Nie, Chong"

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  1. Book: Molecular imaging in oncology

    Schober, Otmar / Riemann, Burkhard

    (Recent results in cancer research ; 187)

    2013  

    Author's details Otmar Schober ; Burkhard Riemann, eds
    Series title Recent results in cancer research ; 187
    Collection
    Keywords Krebs ; Molekulare Bildgebung
    Subject Molecular imaging ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size XV, 415 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT016970238
    ISBN 978-3-642-10852-5 ; 3-642-10852-0 ; 9783642108532 ; 3642108539
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Predictors of Anxiety and Depression in Differentiated Thyroid Cancer Survivors: Results of a Cross-Sectional Study.

    Noto, Benjamin / Asmus, Inga / Schäfers, Michael / Görlich, Dennis / Riemann, Burkhard

    Thyroid : official journal of the American Thyroid Association

    2022  Volume 32, Issue 9, Page(s) 1077–1085

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Anxiety/epidemiology ; Anxiety/etiology ; Anxiety/psychology ; Cancer Survivors ; Cross-Sectional Studies ; Depression/epidemiology ; Depression/etiology ; Depression/psychology ; Female ; Humans ; Male ; Middle Aged ; Quality of Life ; Survivors/psychology ; Thyroid Neoplasms/complications ; Thyroid Neoplasms/psychology
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1086044-7
    ISSN 1557-9077 ; 1050-7256
    ISSN (online) 1557-9077
    ISSN 1050-7256
    DOI 10.1089/thy.2022.0067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Angiogenese-Targeting für Diagnose und Therapie - MoBiMed

    Riemann, Burkhard

    Subprojekt 3: Quantifizierung der Tumorangiogenese und -progression durch in-vivo-Untersuchungen des Endothelin-Systems ; Abschluss-Bericht

    2012  

    Title variant Visualization of the endothelin system to assess tumour angiogenesis and progression in vivo
    Institution Universitätsklinikum Münster
    Author's details Universitätsklinikum Münster. Burkhard Riemann
    Language German
    Size [9] S.
    Publishing place Münster
    Document type Book
    Note Förderkennzeichen BMBF 01EZ0809 [alt] - 13EZ0809 [neu]. - Verbund-Nr. 01067554 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book ; Online: Angiogenese-Targeting für Diagnose und Therapie - MoBiMed

    Riemann, Burkhard

    Subprojekt 3: Quantifizierung der Tumorangiogenese und -progression durch in-vivo-Untersuchungen des Endothelin-Systems ; Abschluss-Bericht

    2012  

    Title variant Visualization of the endothelin system to assess tumour angiogenesis and progression in vivo
    Institution Universitätsklinikum Münster
    Author's details Universitätsklinikum Münster. Burkhard Riemann
    Language German
    Size Online-Ressource (9 S., 226 KB)
    Publisher Technische Informationsbibliothek u. Universitätsbibliothek
    Publishing place Hannover ; Münster
    Document type Book ; Online
    Note Förderkennzeichen BMBF 01EZ0809 [alt] - 13EZ0809 [neu]. - Verbund-Nr. 01067554. - Engl. Berichtsbl. u.d.T.: Visualization of the endothelin system to assess tumour angiogenesis and progression in vivo ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book: Molecular imaging in oncology

    Schober, Otmar / Riemann, Burkhard

    (Recent results in cancer research, ; 187)

    2013  

    Author's details Ottmar Schober, Burkhard Riemann, editors
    Series title Recent results in cancer research, ; 187
    MeSH term(s) Neoplasms/diagnosis ; Diagnostic Imaging ; Molecular Diagnostic Techniques ; Molecular Probes ; Neoplasms/therapy
    Language English
    Size xv, 415 p. :, ill. (some col.) ;, 24 cm.
    Publisher Springer
    Publishing place Berlin ; London
    Document type Book
    ISBN 9783642108525 ; 9783642108532 ; 3642108520 ; 3642108539
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: Diagnostic Performance of [

    Ventura, David / Dittmann, Matthias / Büther, Florian / Schäfers, Michael / Rahbar, Kambiz / Hescheler, Daniel / Claesener, Michael / Schindler, Philipp / Riemann, Burkhard / Seifert, Robert / Roll, Wolfgang

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2024  Volume 65, Issue 2, Page(s) 192–198

    Abstract: ...

    Abstract [
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Fluorodeoxyglucose F18 ; Iodine ; Retrospective Studies ; Neoplasm Recurrence, Local ; Positron-Emission Tomography ; Thyroid Neoplasms/pathology ; Single Photon Emission Computed Tomography Computed Tomography ; Iodine Radioisotopes/therapeutic use ; Adenocarcinoma ; Thyrotropin ; Thyroglobulin
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Iodine (9679TC07X4) ; Iodine Radioisotopes ; Thyrotropin (9002-71-5) ; Thyroglobulin (9010-34-8)
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.123.266513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Minimal extrathyroid extension in papillary micro carcinoma of the thyroid is an independent risk factor for relapse through lymph node and distant metastases.

    Seifert, Robert / Schäfers, Michael Andreas / Heitplatz, Barbara / Kerschke, Laura / Riemann, Burkhard / Noto, Benjamin

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2021  

    Abstract: Aims: ...

    Abstract Aims:
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.121.261898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Anaplastic thyroid cancer: genome-based search for new targeted therapy options.

    Hescheler, Daniel Alexander / Hartmann, Milan Janis Michael / Riemann, Burkhard / Michel, Maximilian / Bruns, Christiane Josephine / Alakus, Hakan / Chiapponi, Costanza

    Endocrine connections

    2022  Volume 11, Issue 4

    Abstract: Objective: Anaplastic thyroid cancer (ATC) is one of the most lethal human cancers with meager treatment options. We aimed to identify the targeted drugs already approved by the Food and Drug Administration (FDA) for solid cancer in general, which could ...

    Abstract Objective: Anaplastic thyroid cancer (ATC) is one of the most lethal human cancers with meager treatment options. We aimed to identify the targeted drugs already approved by the Food and Drug Administration (FDA) for solid cancer in general, which could be effective in ATC.
    Design: Database mining.
    Methods: FDA-approved drugs for targeted therapy were identified by screening the databases of MyCancerGenome and the National Cancer Institute. Drugs were linked to the target genes by querying Drugbank. Subsequently, MyCancerGenome, CIViC, TARGET and OncoKB were mined for genetic alterations which are predicted to lead to drug sensitivity or resistance. We searched the Cancer Genome Atlas database (TCGA) for patients with ATC and probed their sequencing data for genetic alterations which predict a drug response.
    Results: In the study,155 FDA-approved drugs with 136 potentially targetable genes were identified. Seventeen (52%) of 33 patients found in TCGA had at least one genetic alteration in targetable genes. The point mutation BRAF V600E was seen in 45% of patients. PIK3CA occurred in 18% of cases. Amplifications of ALK and SRC were detected in 3% of cases, respectively. Fifteen percent of the patients displayed a co-mutation of BRAF and PIK3CA. Besides BRAF-inhibitors, the PIK3CA-inhibitor copanlisib showed a genetically predicted response. The 146 (94%) remaining drugs showed no or low (under 4% cases) genetically predicted drug response.
    Conclusions: While ATC carrying BRAF mutations can benefit from BRAF inhibitors and this effect might be enhanced by a combined strategy including PIK3CA inhibitors in some of the patients, alterations in BRAFWT ATC are not directly targeted by currently FDA-approved options.
    Language English
    Publishing date 2022-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2668428-7
    ISSN 2049-3614
    ISSN 2049-3614
    DOI 10.1530/EC-21-0624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Targeted Therapy for Adrenocortical Carcinoma: A Genomic-Based Search for Available and Emerging Options.

    Hescheler, Daniel Alexander / Hartmann, Milan Janis Michael / Riemann, Burkhard / Michel, Maximilian / Bruns, Christiane Josephine / Alakus, Hakan / Chiapponi, Costanza

    Cancers

    2022  Volume 14, Issue 11

    Abstract: In rare diseases such as adrenocortical carcinoma (ACC), in silico analysis can help select promising therapy options. We screened all drugs approved by the FDA and those in current clinical studies to identify drugs that target genomic alterations, also ...

    Abstract In rare diseases such as adrenocortical carcinoma (ACC), in silico analysis can help select promising therapy options. We screened all drugs approved by the FDA and those in current clinical studies to identify drugs that target genomic alterations, also known to be present in patients with ACC. We identified FDA-approved drugs in the My Cancer Genome and National Cancer Institute databases and identified genetic alterations that could predict drug response. In total, 155 FDA-approved drugs and 905 drugs in clinical trials were identified and linked to 375 genes of 89 TCGA patients. The most frequent potentially targetable genetic alterations included TP53 (20%), BRD9 (13%), TERT (13%), CTNNB1 (13%), CDK4 (7%), FLT4 (7%), and MDM2 (7%). We identified TP53-modulating drugs to be possibly effective in 20-26% of patients, followed by the Wnt signaling pathway inhibitors (15%), Telomelysin and INO5401 (13%), FHD-609 (13%), etc. According to our data, 67% of ACC patients exhibited genomic alterations that might be targeted by FDA-approved drugs or drugs being tested in current clinical trials. Although there are not many current therapy options directly targeting reported ACC alterations, this study identifies emerging options that could be tested in clinical trials.
    Language English
    Publishing date 2022-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14112721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Risikofaktoren für den permanenten postoperativen Hypoparathyreoidismus.

    Allemeyer, Erik H / Kossow, Marielle S / Riemann, Burkhard / Hoffmann, Matthias W

    Zentralblatt fur Chirurgie

    2019  Volume 145, Issue 2, Page(s) 168–175

    Abstract: Background: Permanent postoperative hypoparathyreoidism remains the most frequent complication after total thyreoidectomy with severe long-term morbidity, impairment of quality of life and economic implications.: Objective: Identification of risk ... ...

    Title translation Risk Factors for Permanent Postoperative Hypoparathyreoidism.
    Abstract Background: Permanent postoperative hypoparathyreoidism remains the most frequent complication after total thyreoidectomy with severe long-term morbidity, impairment of quality of life and economic implications.
    Objective: Identification of risk factors for permanent postoperative hypoparathyreoidism.
    Material and methods: 420 patients received total thyreoidectomy in our endocrine centre between 08/2012 und 08/2014, of whom 382 were included in the study. 117 patients underwent a follow-up investigation between 8 and 32 months postoperatively.
    Results: We determined a low parathyroid hormone level on postoperative day 1, non-application of a drain and a prolonged postoperative hospital stay as being associated with permanent postoperative hypoparathyreoidism. No association was found between postoperative hypoparathyroidism and autotransplantation of a parathyroid gland. Associations were strong but not significant.
    Discussion: We identified associated factors for permanent postoperative hypoparathyreoidism. Larger multicentre studies should be performed for validation as possible relevant risk factors. Knowledge of risk factors might help to avoid this complication and to manage close follow-up and therapy in patients affected.
    MeSH term(s) Humans ; Hypoparathyroidism ; Parathyroid Glands ; Parathyroid Hormone ; Postoperative Complications ; Quality of Life ; Risk Factors ; Thyroidectomy
    Chemical Substances Parathyroid Hormone
    Language German
    Publishing date 2019-02-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 200935-3
    ISSN 1438-9592 ; 0044-409X
    ISSN (online) 1438-9592
    ISSN 0044-409X
    DOI 10.1055/a-0837-1013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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