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  1. Book ; Online ; E-Book: Materia medica of new and old homeopathic medicines

    Riley, David S.

    2022  

    Author's details David S. Riley, editor
    Keywords Homeopathy/Materia medica and therapeutics ; Homeopathy/Research
    Subject code 615.532
    Language English
    Size 1 online resource (284 pages)
    Edition Third edition.
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9783030659202 ; 9783030659196 ; 3030659208 ; 3030659194
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Materia medica of new and old homeopathic medicines

    Riley, David S.

    2018  

    Author's details David S. Riley
    Keywords Medicine ; Complementary medicine
    Subject code 610
    Language English
    Size 1 Online-Ressource (X, 282 Seiten)
    Edition 2nd edition
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019604348
    ISBN 978-3-662-54192-0 ; 9783662541913 ; 3-662-54192-0 ; 3662541912
    DOI 10.1007/978-3-662-54192-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Materia medica of new and old homeopathic medicines

    Riley, David S.

    2012  

    Author's details David S. Riley
    Keywords Arzneimittelbild
    Subject Arzneimittelportrait ; Arzneimittelprüfung ; Homöopathisches Arzneimittel
    Language English
    Size VII, 223 S., 24 cm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017108389
    ISBN 978-3-642-25291-4 ; 3-642-25291-5
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: von Willebrand disease: A guide for the internist.

    Kaur, Varinder / Elghawy, Omar / Deshpande, Saarang / Riley, David

    Cleveland Clinic journal of medicine

    2024  Volume 91, Issue 2, Page(s) 119–127

    Abstract: von Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not make enough von Willebrand factor (VWF) or make defective VWF. The pathophysiology of this disorder is complex but needs to be understood to ... ...

    Abstract von Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not make enough von Willebrand factor (VWF) or make defective VWF. The pathophysiology of this disorder is complex but needs to be understood to interpret the diagnostic tests. Most patients have mild to moderate symptoms and can be adequately counseled and managed by a general internist, but some need to consult a hematologist. We review the pathophysiology of VWD, its subtypes, common presentations of each subtype, diagnostic testing, and management of mild as well as severe clinical manifestations of VWD.
    MeSH term(s) Humans ; von Willebrand Diseases/diagnosis ; von Willebrand Diseases/therapy ; von Willebrand Factor ; Physicians
    Chemical Substances von Willebrand Factor
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639116-3
    ISSN 1939-2869 ; 0891-1150
    ISSN (online) 1939-2869
    ISSN 0891-1150
    DOI 10.3949/ccjm.91a.22033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Improved Health and Well-being: Creating Value in Health Care.

    Riley, David

    Integrative medicine (Encinitas, Calif.)

    2019  Volume 16, Issue 5, Page(s) 16–17

    Language English
    Publishing date 2019-03-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 2100529-1
    ISSN 1945-7081 ; 1546-993X
    ISSN (online) 1945-7081
    ISSN 1546-993X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Influence of shaped boundaries on propagating compaction bands in brittle porous media.

    Riley, David M / Valdes, Julio R / Einav, Itai / Guillard, François

    Physical review. E

    2024  Volume 108, Issue 6-1, Page(s) 64906

    Abstract: The compression of brittle porous media can lead to the propagation of compaction bands. Although such localization phenomena have been observed in different geometries, including cuboidal and axisymmetric uniaxial compression, the role of boundary ... ...

    Abstract The compression of brittle porous media can lead to the propagation of compaction bands. Although such localization phenomena have been observed in different geometries, including cuboidal and axisymmetric uniaxial compression, the role of boundary geometry on compaction features has yet to be explored, despite its relevance in geological conditions and industrial processes. To this end, we investigate the influence of shaped boundaries and inhomogeneous inclusions in a model brittle material made of puffed rice cereal. Using a variety of geometries, we show that compaction bands assume the shape of nearby boundaries, but return to a default planar form a distance away from them. Remarkably, the band aligns parallel to characteristic lines of minor principal stress obtained from a simple linear elastic model. The compelling correlation between the rotation of the principal stress directions and compaction band orientation holds implications for the geological interpretation of localized patterns in rocks and for comprehending the formation of weak planes in pharmaceutical tablets.
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.108.064906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dynamic and transient processes in warm dense matter.

    White, Thomas G / Dai, Jiayu / Riley, David

    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

    2023  Volume 381, Issue 2253, Page(s) 20220223

    Abstract: In this paper, we discuss some of the key challenges in the study of time-dependent processes and non-equilibrium behaviour in warm dense matter. We outline some of the basic physics concepts that have underpinned the definition of warm dense matter as a ...

    Abstract In this paper, we discuss some of the key challenges in the study of time-dependent processes and non-equilibrium behaviour in warm dense matter. We outline some of the basic physics concepts that have underpinned the definition of warm dense matter as a subject area in its own right and then cover, in a selective, non-comprehensive manner, some of the current challenges, pointing along the way to topics covered by the papers presented in this volume. This article is part of the theme issue 'Dynamic and transient processes in warm dense matter'.
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 208381-4
    ISSN 1471-2962 ; 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
    ISSN (online) 1471-2962
    ISSN 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
    DOI 10.1098/rsta.2022.0223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Improving Whitefly Management.

    Simmons, Alvin M / Riley, David G

    Insects

    2021  Volume 12, Issue 5

    Abstract: Whiteflies (Hemiptera: Aleyrodidae), especially the sweetpotato or cotton whitefly, ...

    Abstract Whiteflies (Hemiptera: Aleyrodidae), especially the sweetpotato or cotton whitefly,
    Language English
    Publishing date 2021-05-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects12050470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Augmenting DMTA using predictive AI modelling at AstraZeneca.

    Ghiandoni, Gian Marco / Evertsson, Emma / Riley, David J / Tyrchan, Christian / Rathi, Prakash Chandra

    Drug discovery today

    2024  Volume 29, Issue 4, Page(s) 103945

    Abstract: Design-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are ... ...

    Abstract Design-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are identified, often requiring many cycles before reaching a sweet spot. The advent of artificial intelligence (AI) and cloud computing presents an opportunity to innovate drug discovery to reduce the number of cycles needed to yield a candidate. Here, we present the Predictive Insight Platform (PIP), a cloud-native modelling platform developed at AstraZeneca. The impact of PIP in each step of DMTA, as well as its architecture, integration, and usage, are discussed and used to provide insights into the future of drug discovery.
    MeSH term(s) Artificial Intelligence ; Biological Assay ; Drug Discovery
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1324988-5
    ISSN 1878-5832 ; 1359-6446
    ISSN (online) 1878-5832
    ISSN 1359-6446
    DOI 10.1016/j.drudis.2024.103945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Painful Diabetic Peripheral Neuropathy: Practical Guidance and Challenges for Clinical Management.

    Preston, Frank G / Riley, David R / Azmi, Shazli / Alam, Uazman

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2023  Volume 16, Page(s) 1595–1612

    Abstract: Painful diabetic peripheral neuropathy (PDPN) is present in nearly a quarter of people with diabetes. It is estimated to affect over 100 million people worldwide. PDPN is associated with impaired daily functioning, depression, sleep disturbance, ... ...

    Abstract Painful diabetic peripheral neuropathy (PDPN) is present in nearly a quarter of people with diabetes. It is estimated to affect over 100 million people worldwide. PDPN is associated with impaired daily functioning, depression, sleep disturbance, financial instability, and a decreased quality of life. Despite its high prevalence and significant health burden, it remains an underdiagnosed and undertreated condition. PDPN is a complex pain phenomenon with the experience of pain associated with and exacerbated by poor sleep and low mood. A holistic approach to patient-centred care alongside the pharmacological therapy is required to maximise benefit. A key treatment challenge is managing patient expectation, as a good outcome from treatment is defined as a reduction in pain of 30-50%, with a complete pain-free outcome being rare. The future for the treatment of PDPN holds promise, despite a 20-year void in the licensing of new analgesic agents for neuropathic pain. There are over 50 new molecular entities reaching clinical development and several demonstrating benefit in early-stage clinical trials. We review the current approaches to its diagnosis, the tools, and questionnaires available to clinicians, international guidance on PDPN management, and existing pharmacological and non-pharmacological treatment options. We synthesise evidence and the guidance from the American Association of Clinical Endocrinology, American Academy of Neurology, American Diabetes Association, Diabetes Canada, German Diabetes Association, and the International Diabetes Federation into a practical guide to the treatment of PDPN and highlight the need for future research into mechanistic-based treatments in order to prioritise the development of personalised medicine.
    Language English
    Publishing date 2023-06-02
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S370050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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