Result 1 - 10 of total 595
The Psychological clinic
2017 Volume 18, Issue 3-4, Page(s) 128–132
| Language | English |
|---|---|
| Publishing date | 2017-09-14 |
| Publishing country | United States |
| Document type | Journal Article |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2022 Volume 69, Issue 11, Page(s) e29727
| MeSH term(s) | Histiocytosis, Langerhans-Cell/complications ; Histiocytosis, Langerhans-Cell/diagnosis ; Humans ; Lymphohistiocytosis, Hemophagocytic/diagnosis ; Lymphohistiocytosis, Hemophagocytic/etiology |
|---|---|
| Language | English |
| Publishing date | 2022-06-02 |
| Publishing country | United States |
| Document type | Case Reports ; Letter |
| ZDB-ID | 2131448-2 |
| ISSN | 1545-5017 ; 1545-5009 |
| ISSN (online) | 1545-5017 |
| ISSN | 1545-5009 |
| DOI | 10.1002/pbc.29727 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 1131: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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Journal of biomechanical engineering
2023 Volume 145, Issue 10
Abstract: Previous computer models have successfully predicted cardiac growth and remodeling in adults with pathologies. However, applying these models to infants is complicated by the fact that they also undergo normal, somatic cardiac growth and remodeling. ... ...
| Abstract | Previous computer models have successfully predicted cardiac growth and remodeling in adults with pathologies. However, applying these models to infants is complicated by the fact that they also undergo normal, somatic cardiac growth and remodeling. Therefore, we designed a computational model to predict ventricular dimensions and hemodynamics in healthy, growing infants by modifying an adult canine left ventricular growth model. The heart chambers were modeled as time-varying elastances coupled to a circuit model of the circulation. Circulation parameters were allometrically scaled and adjusted for maturation to simulate birth through 3 yrs of age. Ventricular growth was driven by perturbations in myocyte strain. The model successfully matched clinical measurements of pressures, ventricular and atrial volumes, and ventricular thicknesses within two standard deviations of multiple infant studies. To test the model, we input 10th and 90th percentile infant weights. Predicted volumes and thicknesses decreased and increased within normal ranges and pressures were unchanged. When we simulated coarctation of the aorta, systemic blood pressure, left ventricular thickness, and left ventricular volume all increased, following trends in clinical data. Our model enables a greater understanding of somatic and pathological growth in infants with congenital heart defects. Its flexibility and computational efficiency when compared to models employing more complex geometries allow for rapid analysis of pathological mechanisms affecting cardiac growth and hemodynamics. |
|---|---|
| MeSH term(s) | Animals ; Dogs ; Hemodynamics ; Heart Ventricles ; Heart ; Aorta ; Computer Simulation |
| Language | English |
| Publishing date | 2023-07-05 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 243094-0 |
| ISSN | 1528-8951 ; 0148-0731 |
| ISSN (online) | 1528-8951 |
| ISSN | 0148-0731 |
| DOI | 10.1115/1.4062779 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.B 2672: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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Trends in endocrinology and metabolism: TEM
2023 Volume 35, Issue 2, Page(s) 88–90
Abstract: High dietary fructose consumption is linked to multiple disease states, including cancer. Zhou and colleagues recently reported a novel mechanism where high dietary fructose levels increase acetate production by the gut microbiome increasing post- ... ...
| Abstract | High dietary fructose consumption is linked to multiple disease states, including cancer. Zhou and colleagues recently reported a novel mechanism where high dietary fructose levels increase acetate production by the gut microbiome increasing post-translational modification O-GlcNAcylation in liver cells, which contributes to disease progression in mouse models of hepatocellular carcinoma. |
|---|---|
| MeSH term(s) | Mice ; Animals ; Fructose/adverse effects ; Liver Neoplasms/pathology ; Carcinoma, Hepatocellular/pathology ; Protein Processing, Post-Translational ; Acetates |
| Chemical Substances | Fructose (30237-26-4) ; Acetates |
| Language | English |
| Publishing date | 2023-12-13 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 1042384-9 |
| ISSN | 1879-3061 ; 1043-2760 |
| ISSN (online) | 1879-3061 |
| ISSN | 1043-2760 |
| DOI | 10.1016/j.tem.2023.12.002 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2999: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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2018 Volume 169, Issue 8, Page(s) 589
| MeSH term(s) | Global Health ; Moral Obligations ; Social Justice ; United States |
|---|---|
| Language | English |
| Publishing date | 2018-11-15 |
| Publishing country | United States |
| Document type | Letter ; Comment |
| ZDB-ID | 336-0 |
| ISSN | 1539-3704 ; 0003-4819 |
| ISSN (online) | 1539-3704 |
| ISSN | 0003-4819 |
| DOI | 10.7326/L18-0382 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.178/2: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2024 Volume 14, Page(s) 1327404
Abstract: Objective: The primary aim of this study was to identify predictive factors associated with onset of : Methods: A retrospective analysis was conducted on 211 patients who underwent EES. Logistic regression models were employed for the primary and ... ...
| Abstract | Objective: The primary aim of this study was to identify predictive factors associated with onset of Methods: A retrospective analysis was conducted on 211 patients who underwent EES. Logistic regression models were employed for the primary and secondary objectives. Patients were stratified into specific groups based on surgical indications and prolactin levels for nuanced analysis. Results: Significant predictors for Conclusion: This study identifies key predictors for outcomes in pituitary surgery. Our research is the first to employ individualized success criteria for EES, challenging existing perceptions about the role of age and adenoma size. These findings open avenues for nuanced, individualized preoperative risk assessment and postoperative management. |
|---|---|
| MeSH term(s) | Humans ; Male ; Pituitary Neoplasms/surgery ; Pituitary Neoplasms/complications ; Prognosis ; Retrospective Studies ; Prolactin ; Treatment Outcome ; Adenoma/surgery ; Adenoma/complications ; Hypopituitarism/complications |
| Chemical Substances | Prolactin (9002-62-4) |
| Language | English |
| Publishing date | 2024-01-11 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2592084-4 |
| ISSN | 1664-2392 |
| ISSN | 1664-2392 |
| DOI | 10.3389/fendo.2023.1327404 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Journal of paediatrics and child health
2022 Volume 59, Issue 2, Page(s) 385–388
| MeSH term(s) | Pregnancy ; Female ; Infant, Newborn ; Humans ; Herpes Simplex/diagnosis ; Herpes Simplex/drug therapy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/drug therapy |
|---|---|
| Language | English |
| Publishing date | 2022-11-10 |
| Publishing country | Australia |
| Document type | Case Reports |
| ZDB-ID | 1024476-1 |
| ISSN | 1440-1754 ; 1034-4810 |
| ISSN (online) | 1440-1754 |
| ISSN | 1034-4810 |
| DOI | 10.1111/jpc.16278 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 227: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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Desenzano del Garda, Italy, 19 - 23 March 2012
2015
| Event/congress | International ICST Conference on Simulation Tools and Techniques (5, 2012.03.19-23, DesenzanodelGarda) ; Simutools (5, 2012.03.19-23, DesenzanodelGarda) |
|---|---|
| Author's details | G. Riley |
| Language | English |
| Size | 225 S. |
| Publisher | Curran |
| Publishing place | Red Hook, NY |
| Document type | Book ; Conference proceedings |
| ISBN | 9781634395670 ; 1634395670 |
| Database | Library catalogue of the German National Library of Science and Technology (TIB), Hannover |
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International journal of experimental pathology
2013 Volume 94, Issue 4, Page(s) 241
| MeSH term(s) | Humans ; Tendinopathy/physiopathology ; Tendinopathy/therapy |
|---|---|
| Language | English |
| Publishing date | 2013-07-09 |
| Publishing country | England |
| Document type | Introductory Journal Article |
| ZDB-ID | 1016006-1 |
| ISSN | 1365-2613 ; 0958-4625 ; 0007-1021 ; 0959-9673 |
| ISSN (online) | 1365-2613 |
| ISSN | 0958-4625 ; 0007-1021 ; 0959-9673 |
| DOI | 10.1111/iep.12039 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ud II Zs.52: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2023 Volume 30, Issue 1, Page(s) 302–314
Abstract: Introduction: Among chronically ill populations, affective disorders remain underdiagnosed and undertreated. A high degree of comorbidity exists between diabetes and affective disorders, particularly depression and anxiety. The mechanisms underlying ... ...
| Abstract | Introduction: Among chronically ill populations, affective disorders remain underdiagnosed and undertreated. A high degree of comorbidity exists between diabetes and affective disorders, particularly depression and anxiety. The mechanisms underlying stress-induced affective dysregulation are likely distinct from those induced by diabetes. A direct comparison between stress- and hyperglycemia-induced affective dysregulation could provide insight into distinct mechanistic targets for depression/anxiety associated with these different conditions. Methods: To this end, the present study used male C57BL/6J mice to compare the independent and combined behavioral and neuroinflammatory effects of two models: (1) unpredictable chronic mild stress and (2) pharmacologically induced hyperglycemia. Results: Streptozotocin-induced hyperglycemia was associated with a set of behavioral changes reflective of the neurovegetative symptoms of depression (i.e., reduced open field activity, reduced grooming, increased immobility in the forced swim task, and decreased marble burying), increased hippocampal Bdnf and Tnf expression, and elevations in frontal cortex Il1b expression. Our chronic stress protocol produced alterations in anxiety-like behavior and decreased frontal cortex Il1b expression. Discussion: While the combination of chronic stress and hyperglycemia produced limited additive effects, their combination exacerbated total symptom burden. Overall, the data indicate that stress and hyperglycemia induce different symptom profiles via distinct mechanisms. |
|---|---|
| MeSH term(s) | Mice ; Male ; Animals ; Depression ; Mice, Inbred C57BL ; Anxiety ; Hippocampus/metabolism ; Hyperglycemia/metabolism ; Diabetes Mellitus/metabolism ; Stress, Psychological/complications ; Stress, Psychological/metabolism ; Disease Models, Animal ; Behavior, Animal/physiology |
| Language | English |
| Publishing date | 2023-10-18 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 1184368-8 |
| ISSN | 1423-0216 ; 1021-7401 |
| ISSN (online) | 1423-0216 |
| ISSN | 1021-7401 |
| DOI | 10.1159/000534669 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 3975: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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