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  1. Article ; Online: Microwave ablation of colorectal liver metastases: Impact of a 10-mm safety margin on local recurrence in a tertiary care hospital.

    Ausania, Fabio / Borin, Alex / Melendez, Reyes / Rio, Paula Senra Del / Iglesias, Alfonso / Bodenlle, Pilar / Paniagua, Marta / Arias, Mercedes

    Annals of hepato-biliary-pancreatic surgery

    2021  Volume 25, Issue 3, Page(s) 366–370

    Abstract: Microwave ablation (MWA) for colorectal liver metastasis (CLM) has been traditionally considered inferior to surgery due to the higher rate of local recurrence. The study investigated whether a safety margin of 10 mm can improve local control in patients ...

    Abstract Microwave ablation (MWA) for colorectal liver metastasis (CLM) has been traditionally considered inferior to surgery due to the higher rate of local recurrence. The study investigated whether a safety margin of 10 mm can improve local control in patients undergoing surgical MWA. Surgical MWA was used to treat 53 lesions in 22 patients with CLM at our Institution from June 2012 to June 2017. The patients' mean age was 64.5 years, and the median size of the lesion was 16.5 mm (9-34 mm). MWA was associated with liver resection in 16 patients (72.7%). The median follow-up was 32.4 months. Univariate and multivariate analyses were performed to identify factors associated with tumor recurrence. Median ablation area was 36.6 mm
    Language English
    Publishing date 2021-08-17
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3012179-6
    ISSN 2508-5859 ; 2508-5778
    ISSN (online) 2508-5859
    ISSN 2508-5778
    DOI 10.14701/ahbps.2021.25.3.366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Repeated pancreatic resection for pancreatic metastases from renal cell Carcinoma: A Spanish multicenter study (PANMEKID).

    Rojas-Holguín, Adela / Fondevila-Campo, Constantino / Sanjuanbenito, Alfonso / Fabregat-Prous, Joan / Secanella-Medayo, Luís / Rotellar-Sastre, Fernando / Pardo-Sánchez, Fernando / Prieto-Calvo, Mikel / Marín-Ortega, Héctor / Sánchez-Cabús, Santiago / Diez-Valladares, Luis / Alonso-Casado, Óscar / González-Serrano, Carmen / Rodríguez-Sanjuan, Juan Carlos / García-Plaza, Gabriel / Jaén-Torrejimeno, Isabel / Suárez-Muñoz, Miguel Ángel / Becerra-Massare, Antonio / Rio, Paula Senra-Del /
    Pando, Elizabeth / López-Andújar, Rafael / Muñoz-Forner, Elena / Rodriguez-López, Mario / Pereira, Fernando / Serrablo-Requejo, Alejandro / Turrión, Víctor Sánchez / Garrido, Manuel Jiménez / Burdío, Fernando / Martín-Pérez, Elena / Estevan-Estevan, Rafael / López-Guerra, Diego / Castell-Gómez, José / Salinas-Gómez, Javier / López-Baena, José Ángel / López-Ben, Santiago / Solar-García, Lorena / Pérez-Alonso, Alejandro J / Martínez-Insfran, Luis Alberto / Blas, Juan Luis / Cornejo, Marian / Gutierrez-Calvo, Alberto / Pozo, Carlos Domingo-Del / Ochando-Cerdan, Federico / Muñoz-Bellvís, Luis / Rebollar-Saenz, José / Sánchez, Belinda / Jover, José María / Gómez-Bravo, Miguel Ángel / Ramia, José M / Blanco-Fernández, Gerardo

    Surgical oncology

    2024  Volume 52, Page(s) 102039

    Abstract: Background and objectives: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in ... ...

    Abstract Background and objectives: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in the pancreatic remnant and its surgical treatment with a repeated pancreatic resection, and to analyse the results of both overall and disease-free survival.
    Methods: Multicenter retrospective study of patients undergoing pancreatic resection for RCC pancreatic metastases, from January 2010 to May 2020. Patients were grouped into two groups depending on whether they received a single pancreatic resection (SPS) or iterative pancreatic resection. Data on short and long-term outcome after pancreatic resection were collected.
    Results: The study included 131 pancreatic resections performed in 116 patients. Thus, iterative pancreatic surgery (IPS) was performed in 15 patients. The mean length of time between the first pancreatic surgery and the second was 48.9 months (95 % CI: 22.2-56.9). There were no differences in the rate of postoperative complications. The DFS rates at 1, 3 and 5 years were 86 %, 78 % and 78 % vs 75 %, 50 % and 37 % in the IPS and SPS group respectively (p = 0.179). OS rates at 1, 3, 5 and 7 years were 100 %, 100 %, 100 % and 75 % in the IPS group vs 95 %, 85 %, 80 % and 68 % in the SPS group (p = 0.895).
    Conclusion: Repeated pancreatic resection in case of relapse of pancreatic metastasis of RCC in the pancreatic remnant is justified, since it achieves OS results similar to those obtained after the first resection.
    MeSH term(s) Humans ; Carcinoma, Renal Cell/surgery ; Carcinoma, Renal Cell/pathology ; Retrospective Studies ; Pancreatectomy/methods ; Pancreatic Neoplasms/pathology ; Kidney Neoplasms/surgery ; Kidney Neoplasms/pathology ; Recurrence
    Language English
    Publishing date 2024-01-27
    Publishing country Netherlands
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1107810-8
    ISSN 1879-3320 ; 0960-7404
    ISSN (online) 1879-3320
    ISSN 0960-7404
    DOI 10.1016/j.suronc.2024.102039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pancreatic metastases from renal cell carcinoma. Postoperative outcome after surgical treatment in a Spanish multicenter study (PANMEKID).

    Blanco-Fernández, Gerardo / Fondevila-Campo, Constantino / Sanjuanbenito, Alfonso / Fabregat-Prous, Joan / Secanella-Medayo, Luís / Rotellar-Sastre, Fernando / Pardo-Sánchez, Fernando / Prieto-Calvo, Mikel / Marín-Ortega, Héctor / Sánchez-Cabús, Santiago / Diez-Valladares, Luis / Alonso-Casado, Óscar / González-Serrano, Carmen / Rodríguez-Sanjuan, Juan Carlos / García-Plaza, Gabriel / Jaén-Torrejimeno, Isabel / Suárez-Muñoz, Miguel Ángel / Becerra-Massare, Antonio / Rio, Paula Senra-Del /
    Pando, Elizabeth / López-Andújar, Rafael / Muñoz-Forner, Elena / Rodriguez-López, Mario / Pereira, Fernando / Serrablo-Requejo, Alejandro / Turrión, Víctor Sánchez / Garrido, Manuel Jiménez / Burdío, Fernando / Martín-Pérez, Elena / Estevan-Estevan, Rafael / López-Guerra, Diego / Castell-Gómez, José / Salinas-Gómez, Javier / López-Baena, José Ángel / López-Ben, Santiago / Solar-García, Lorena / Pérez-Alonso, Alejandro J / Martínez-Insfran, Luis Alberto / Blas, Juan Luis / Cornejo, Marian / Gutierrez-Calvo, Alberto / Pozo, Carlos Domingo-Del / Ochando-Cerdan, Federico / Muñoz-Bellvís, Luis / Rebollar-Saenz, José / Sánchez, Belinda / Jover, José María / Gómez-Bravo, Miguel Ángel / Ramia, José M / Rojas-Holguín, Adela

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2021  Volume 48, Issue 1, Page(s) 133–141

    Abstract: Background: Renal Cell Carcinoma (RCC) occasionally spreads to the pancreas. The purpose of our study is to evaluate the short and long-term results of a multicenter series in order to determine the effect of surgical treatment on the prognosis of these ...

    Abstract Background: Renal Cell Carcinoma (RCC) occasionally spreads to the pancreas. The purpose of our study is to evaluate the short and long-term results of a multicenter series in order to determine the effect of surgical treatment on the prognosis of these patients.
    Methods: Multicenter retrospective study of patients undergoing surgery for RCC pancreatic metastases, from January 2010 to May 2020. Variables related to the primary tumor, demographics, clinical characteristics of metastasis, location in the pancreas, type of pancreatic resection performed and data on short and long-term evolution after pancreatic resection were collected.
    Results: The study included 116 patients. The mean time between nephrectomy and pancreatic metastases' resection was 87.35 months (ICR: 1.51-332.55). Distal pancreatectomy was the most performed technique employed (50 %). Postoperative morbidity was observed in 60.9 % of cases (Clavien-Dindo greater than IIIa in 14 %). The median follow-up time was 43 months (13-78). Overall survival (OS) rates at 1, 3, and 5 years were 96 %, 88 %, and 83 %, respectively. The disease-free survival (DFS) rate at 1, 3, and 5 years was 73 %, 49 %, and 35 %, respectively. Significant prognostic factors of relapse were a disease free interval of less than 10 years (2.05 [1.13-3.72], p 0.02) and a history of previous extrapancreatic metastasis (2.44 [1.22-4.86], p 0.01).
    Conclusions: Pancreatic resection if metastatic RCC is found in the pancreas is warranted to achieve higher overall survival and disease-free survival, even if extrapancreatic metastases were previously removed. The existence of intrapancreatic multifocal compromise does not always warrant the performance of a total pancreatectomy in order to improve survival.
    MeSH term(s) Aged ; Carcinoma, Renal Cell/secondary ; Carcinoma, Renal Cell/surgery ; Female ; Humans ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Male ; Metastasectomy ; Middle Aged ; Nephrectomy ; Pancreatectomy ; Pancreatic Neoplasms/secondary ; Pancreatic Neoplasms/surgery ; Postoperative Complications/epidemiology ; Spain/epidemiology ; Treatment Outcome
    Language English
    Publishing date 2021-08-11
    Publishing country England
    Document type Journal Article ; Multicenter Study
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2021.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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