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  1. Article ; Online: Treatment of non-infectious retinal vasculitis.

    Rivera, Paola A / Gupta, Akash / Kombo, Ninani

    Therapeutic advances in ophthalmology

    2023  Volume 15, Page(s) 25158414231152761

    Abstract: Retinal vasculitis (RV) refers to an entity in which the retinal vasculature is inflamed, frequently with indications of inflammation elsewhere in the eye. Non-infectious RV can be idiopathic or associated with systemic disease, ocular conditions, and ... ...

    Abstract Retinal vasculitis (RV) refers to an entity in which the retinal vasculature is inflamed, frequently with indications of inflammation elsewhere in the eye. Non-infectious RV can be idiopathic or associated with systemic disease, ocular conditions, and malignancy. It can also be classified based on the vessel affected: artery, vein, or both. Due to the lack of strong evidence-based treatment trials and algorithms for RV, physicians must often rely on their experience, which creates great variability in treating this entity. This article provides an overview of various treatment modalities used in the management of non-infectious RV, with a focus on immunomodulatory therapies. We outline a potential stepwise approach of starting with steroids to control the acute inflammation and subsequently changing to immunomodulatory therapy (IMT) for long-term treatment.
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2515-8414
    ISSN (online) 2515-8414
    DOI 10.1177/25158414231152761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Music During Cataract Surgery: Impact on Anxiety.

    Rivera, Paola A / Linderman, Wendy L / Miguez, Sofia / Chow, Jessica / DeBroff, Brian / Diaz, Vicente

    Journal of cataract and refractive surgery

    2024  

    Abstract: Purpose: To determine the effect of playing patient-selected music intra-operatively on patient self-reported anxiety and the amount of sedative administered during cataract surgery.: Setting: Yale New Haven Hospital health system, New Haven, CT.: ... ...

    Abstract Purpose: To determine the effect of playing patient-selected music intra-operatively on patient self-reported anxiety and the amount of sedative administered during cataract surgery.
    Setting: Yale New Haven Hospital health system, New Haven, CT.
    Design: Prospective, randomized, controlled clinical trial.
    Methods: Patients were randomized to either music group or control group, which had no music played. Patients were blinded to the purpose of the study. On postoperative day 1, patients were consented to participate in the study and asked to complete a six-question Likert-style survey (modified from the State-Trait Anxiety Inventory) assessing anxiety at baseline and during surgery. Patients' intraoperative and postoperative vitals were recorded. The medication, dosage, and number of sedative injections given were also recorded. Paired t-tests were used to assess for significant differences between the two groups.
    Results: A total of 107 patients (mean age 71.2 years) were enrolled in the study. There was no significant difference in baseline anxiety between the two groups. Patients randomized to the music group had significantly lower total self-reported anxiety (mean 5.98) than the control group (mean 7.13, p=0.006). Moreover, patients exposed to music felt significantly less frightened, nervous, and confused during surgery (p=0.002, 0.007, and 0.017, respectively). There was no significant difference between the groups in number and dosage of sedatives given.
    Conclusion: Playing patient-selected music during cataract surgery is an effective way to decrease anxiety. Music has a direct impact on patient experience and is an inexpensive, low-risk method of reducing patient anxiety during surgery.
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/j.jcrs.0000000000001444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Female Authorship and Ophthalmology Journal Editorial Board Membership Trends Over the Last Decade, 2012-2021.

    Rivera, Paola A / Atayde, Agata / Wang, Lei / Kombo, Ninani

    American journal of ophthalmology

    2023  Volume 255, Page(s) 107–114

    Abstract: Purpose: To study the relationship between female authorship and editorial board membership in 3 ophthalmology journals from 2012 to 2021.: Design: Cross-sectional and trend study.: Methods: The prevalence of female first, senior authorship, and ... ...

    Abstract Purpose: To study the relationship between female authorship and editorial board membership in 3 ophthalmology journals from 2012 to 2021.
    Design: Cross-sectional and trend study.
    Methods: The prevalence of female first, senior authorship, and editorial board members were examined in Ophthalmology, JAMA Ophthalmology, and American Journal of Ophthalmology. Gender-API assigned gender to authors based on name and country. Editorial board (EB) information was manually extracted and grouped for comparison among leadership positions. Gender data collected on authorship and EB membership were compared. The proportion of women in EB positions was identified: editor-in-chief, mid-level editors, and consulting editors. Relationship between female authorship and editorial board membership was analyzed.
    Results: Women published fewer articles as first (1547/4267) and senior (1165/4267) authors than did men. The proportion of women in senior authorship significantly increased from 2012 to 2021 (23.4% to 30.5%, P = .0046). Across EB, a significant increase in female members (13.9% to 34.6%, P = .0006) was observed. There was a significant correlation (P < .0001) between female EB members and female authors (r = 0.74, 95% CI = 0.51-0.87) for all journals. The odds of female first authorships were 1.89 (95% CI = 1.65-2.17) times higher for articles with female senior authors than for male senior authors (P < .0001).
    Conclusion: Female senior authorship significantly increased over the last decade. Journals with a higher representation of female EB members also had a higher representation of female authorship. This study found a positive association between first and senior female authorship; however, the gender gap persists. Continued efforts to reach equity in publications and EB representation are necessary.
    Language English
    Publishing date 2023-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2023.07.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ul I Zs.39: Show issues Location:
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  4. Article ; Online: Gender Distribution and Trends of Ophthalmology Subspecialties, 1992-2020.

    Steren, Benjamin J / Yee, Philina / Rivera, Paola A / Feng, Shu / Pepple, Kathryn / Kombo, Ninani

    American journal of ophthalmology

    2023  Volume 253, Page(s) 22–28

    Abstract: Purpose: To describe the gender trends in ophthalmology primary practice areas using the American Board of Ophthalmology (ABO) diplomates.: Design: A trend study plus a cross-sectional study of the ABO's database.: Methods: The de-identified ... ...

    Abstract Purpose: To describe the gender trends in ophthalmology primary practice areas using the American Board of Ophthalmology (ABO) diplomates.
    Design: A trend study plus a cross-sectional study of the ABO's database.
    Methods: The de-identified records of all (N = 12,844) ABO-certified ophthalmologists between 1992 and 2020 were obtained. The year of certification, gender, and self-reported primary practice for each ophthalmologist was recorded. Subspecialty was defined as the self-reported primary practice emphasis. Practice trends of the entire population and the subpopulation of subspecialists were explored based on gender and were then visualized using tables and graphs and analyzed using the χ
    Results: A total of 12,844 board-certified ophthalmologists were included. Nearly half (47%) reported a subspecialty as their primary practice area (n = 6042), of whom the majority were male (65%, n = 3940). In the first decade, men outnumbered women reporting subspecialty practices by more than 2:1. Over time, the number of women subspecialists increased whereas the number of men remained stable, such that by 2020 women comprised almost half of new ABO diplomates reporting subspecialty practice. When all subspecialists were compared within gender, there was not a significant difference (P = .15) between the percentage of male (46%) and female (48%) ophthalmologist reporting a subspecialty practice. However, a significantly greater proportion of women than men reported primary practice in pediatrics (20.1% vs 7.9%, P < .001) and glaucoma (21.8% vs 16.0%, P < .0001). Alternatively, a significantly greater proportion of men reported primary practice in vitreoretinal surgery (47.2% vs 22.0%, P < .0001). There was no significant difference between the proportion of men and women reporting cornea (P = .15) or oculoplastics (P = .31).
    Conclusions: The number of women in ophthalmology subspecialty practice has increased steadily over the past 30 years. Men and women subspecialize at the same rate, but significant differences exist between the types of ophthalmology practiced by each gender.
    MeSH term(s) Humans ; Male ; Female ; Child ; United States ; Ophthalmology ; Cross-Sectional Studies ; Certification ; Ophthalmologists ; Self Report
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2023.04.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: High frequency of symptoms suggestive of endometriosis in a clinic-based sample of low-income women in Mexico City.

    Harris, Courtney / Willie, Tiara C / Cardoso, Lauren F / Campos Rivera, Paola A / Olavarrieta, Claudia Diaz / Pollack, Anna Z / Gupta, Jhumka

    World medical & health policy

    2018  Volume 10, Issue 4, Page(s) 415–419

    Abstract: Endometriosis affects an estimated 10 percent of women and girls globally, yet little is known about symptoms and awareness among women in low- and middle-income countries. This commentary presents a descriptive secondary analysis of baseline data from a ...

    Abstract Endometriosis affects an estimated 10 percent of women and girls globally, yet little is known about symptoms and awareness among women in low- and middle-income countries. This commentary presents a descriptive secondary analysis of baseline data from a clinic-based intervention study with low-income women in Mexico City who experienced intimate partner violence in the past year(N = 754). The secondary analysis examined symptoms that may be suggestive of endometriosis as well as endometriosis awareness. Over half of participants reported at least one symptom suggestive of endometriosis (59.3 percent), while 12.5 percent of those reporting a symptom had ever heard of the disease. Pain-related symptoms were classified as pain with menses disrupting household chores, pain with menses disrupting work or social gatherings, and/or pelvic pain outside of menses disrupting daily activities. Fewer women who reported pain-related symptoms had heard of the disease compared to those who reported a history of infertility (11.4 vs. 15.7 percent, respectively).This study documents levels of awareness of endometriosis among women in Mexico City and underscores the importance of integrating endometriosis education into broader global reproductive health agendas.
    Language English
    Publishing date 2018-11-21
    Publishing country United States
    Document type Journal Article
    ISSN 2153-2028
    ISSN 2153-2028
    DOI 10.1002/wmh3.283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cortical plasticity catalyzed by prehabilitation enables extensive resection of brain tumors in eloquent areas.

    Rivera-Rivera, Paola A / Rios-Lago, Marcos / Sanchez-Casarrubios, Sandra / Salazar, Osman / Yus, Miguel / González-Hidalgo, Mercedes / Sanz, Ana / Avecillas-Chasin, Josué / Alvarez-Linera, Juan / Pascual-Leone, Alvaro / Oliviero, Antonio / Barcia, Juan A

    Journal of neurosurgery

    2016  Volume 126, Issue 4, Page(s) 1323–1333

    Abstract: OBJECTIVE The extent of resection is the most important prognostic factor following brain glioma surgery. However, eloquent areas within tumors limit the extent of resection and, thus, critically affect outcomes. The authors hypothesized that presurgical ...

    Abstract OBJECTIVE The extent of resection is the most important prognostic factor following brain glioma surgery. However, eloquent areas within tumors limit the extent of resection and, thus, critically affect outcomes. The authors hypothesized that presurgical suppression of the eloquent areas within a tumor by continuous cortical electrical stimulation, coupled with appropriate behavioral training ("prehabilitation"), would induce plastic reorganization and enable a more extensive resection. METHODS The authors report on 5 patients harboring gliomas involving eloquent brain areas within tumors as identified on intraoperative stimulation mapping. A grid of electrodes was placed over the residual tumor, and continuous cortical electrical stimulation was targeted to the functional areas. The stimulation intensity was adjusted daily to provoke a mild functional impairment while the function was intensively trained. RESULTS The stimulation intensity required to impair function increased progressively in all patients, and all underwent another operation a mean of 33.6 days later (range 27-37 days), when the maximal stimulation voltage in all active contacts induced no functional deficit. In all cases, a substantially more extensive resection of the tumor was possible. Intraoperative mapping and functional MRI demonstrated a plastic reorganization, and most previously demonstrated eloquent areas within the tumor were silent, while there was new functional activation of brain areas in the same region or toward the contralateral hemisphere. CONCLUSIONS Prehabilitation with continuous cortical electrical stimulation and appropriate behavioral training prior to surgery in patients with WHO Grade II and III gliomas affecting eloquent areas accelerate plastic changes. This can help maximize tumor resection and, thus, improve survival while maintaining function.
    MeSH term(s) Adult ; Brain Mapping ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Brain Neoplasms/physiopathology ; Brain Neoplasms/surgery ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/pathology ; Cerebral Cortex/physiopathology ; Cerebral Cortex/surgery ; Electric Stimulation Therapy ; Female ; Glioma/diagnostic imaging ; Glioma/pathology ; Glioma/physiopathology ; Glioma/surgery ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Neural Pathways/diagnostic imaging ; Neural Pathways/pathology ; Neural Pathways/physiopathology ; Neural Pathways/surgery ; Neurological Rehabilitation/methods ; Neuronal Plasticity/physiology ; Neurosurgical Procedures ; Postoperative Complications/prevention & control ; Preoperative Care/methods ; Treatment Outcome
    Language English
    Publishing date 2016-05-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2016.2.JNS152485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.135: Show issues Location:
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