LIVIVO - Search results -

Search results

Result 1 - 10 of total 25

Search options

Article ; Online: Somatropina y talla final en población pediátrica mexicana con deficiencia de hormona de crecimiento.

Rivera-Hernández, Aleida / Sánchez-García, Fernanda / Zurita-Cruz, Jessie / Balcázar-Hernández, Lourdes

Andes pediatrica : revista Chilena de pediatria

2023 Volume 93, Issue 4, Page(s) 496–503

Abstract: Treatment with recombinant growth hormone, or somatropin, increases linear growth and is effective in improving final height in children with isolated growth hormone deficiency (IGHD), however, the available information of these results in the Latin ... ...

Title translation	Somatropin and final height in Mexican paediatric population with growth hormone deficiency.
Abstract	Treatment with recombinant growth hormone, or somatropin, increases linear growth and is effective in improving final height in children with isolated growth hormone deficiency (IGHD), however, the available information of these results in the Latin population is scarce. Objective: To evaluate the effect of somatropin on growth velocity and final height in Mexican children with IGHD, as well as to determine the factors associated with final height. Patients and method: A retrospective study was conducted in 50 children with isolated and severe growth hormone deficiency treated with somatro pin. Auxological characteristics were assessed before somatropin and at final height. Only patients with severe GH deficiency, with a peak GH value < 5 μg/L, were included. Results: 40% (n = 20) were girls. The basal height Z-score was -2.6 ± 0.4 vs final height Z-score 1.6 ± 0.7, with a Z-score of height in crease of 1 ± 0.6. Ninety-two percent (n = 46) reached their genetic potential; somatropin dose was 33 ± 0.5 μg/kg/d, with a treatment duration of 4.16 ± 1.5 years. The highest growth velocity was observed during the first year. In the multivariate analysis, the association between final height, mid-parental target height (r = 0.30; p = 0.03, β = 0.7; p = 0.001), and somatropin dose (r = 0.63; p = 0.001, β = 0.30; p = 0.028) was observed. Conclusions: Somatropin treatment allows normalization of linear growth and the achievement of genetic height potential in most Mexican children with IGHD. Final height is associated with mid-parental height and somatropin dose, highlighting the importance of genetic potential and the dose-response effect of somatropin in establishing height prognosis.
MeSH term(s)	Child ; Female ; Humans ; Male ; Body Height/genetics ; Dwarfism, Pituitary/drug therapy ; Human Growth Hormone/therapeutic use ; Human Growth Hormone/pharmacology ; Retrospective Studies
Chemical Substances	Human Growth Hormone (12629-01-5)
Language	Spanish
Publishing date	2023-10-31
Publishing country	Chile
Document type	English Abstract ; Journal Article
ISSN	2452-6053
ISSN (online)	2452-6053
DOI	10.32641/andespediatr.v93i4.3763
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control?

Balcázar-Hernández, Lourdes / Huerta-Martínez, Hebert / Garrido Magaña, Eulalia / Nishimura-Meguro, Elisa / Jiménez Márquez, Abigail / Rivera-Hernández, Aleida

Frontiers in endocrinology

2023 Volume 13, Page(s) 1089160

Abstract: Objective: The requirement of a chronic treatment and the increase in life expectancy in children with type 1 diabetes (T1D) leads to the possibility of caregiver burden. The aim of our study was to evaluate the burden in primary informal caregivers ( ... ...

Abstract	Objective: The requirement of a chronic treatment and the increase in life expectancy in children with type 1 diabetes (T1D) leads to the possibility of caregiver burden. The aim of our study was to evaluate the burden in primary informal caregivers (PIC) of children and adolescents with type 1 diabetes and its association with depression, family dysfunction, and glycemic control. Materials and methods: A retrospective study was performed in PIC of children and adolescents with T1D. Zarit Burden Interview Scale (ZBIS) was used to evaluate caregiver burden. Beck Depression Inventory (BDI-II) was used to evaluate depression in PIC, and the Family APGAR questionnaire was used to evaluate the family functionality. Results: A total of 100 PIC of children and adolescents with T1D were included. Caregiver burden was found in 33% of caregivers. The total score of the Zarit scale was 41 (34-49); 19% had mild caregiver burden, and 14% had severe caregiver burden. According to the BDI-II, 82% had minimal depression, 11% mild depression, 5% moderate depression, and 2% severe depression. Family function was good in 69%; 13% had moderate dysfunction, and 18% had severe dysfunction. A positive correlation between caregiver burden and BDI-II score (r = 0.84; p = 0.001) and the grade of depression (r = 0.87; p = 0.001) was found. A logistic regression model showed that BDI-II score was associated with caregiver burden (OR 1.14; 95% CI 1.061-1.23; p = 0.001). A BDI-II cut off of 9 or more had a sensibility and specificity of 58% and 28%, respectively, for caregiver burden [AUC 0.751 (0.64-0.85); p = 0.001]. A BDI-II score ≥9 was a predictor of caregiver burden (OR 3.4; 95% CI 1.4-8.1; p = 0.008). Conclusion: Caregiver burden is present in more than one third of the PIC of patients with T1D and is associated with depression. A BDI-II score ≥9 is a predictor of caregiver burden which may be a point to take into account in the integral approach to the patient with T1D and his or her family nucleus.
MeSH term(s)	Humans ; Male ; Child ; Adolescent ; Female ; Diabetes Mellitus, Type 1/therapy ; Caregivers ; Depression/epidemiology ; Depression/etiology ; Glycemic Control ; Retrospective Studies ; Stress, Psychological
Language	English
Publishing date	2023-01-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2022.1089160
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Leptin/adiponectin ratio as a prognostic factor for increased weight gain in girls with central precocious puberty.

Zurita-Cruz, Jessie Nallely / Villasís-Keever, Miguel Angel / Manuel-Apolinar, Leticia / Damasio-Santana, Leticia / Garrido-Magaña, Eulalia / Rivera-Hernández, Aleida de Jesús

Frontiers in endocrinology

2023 Volume 14, Page(s) 1101399

Abstract: Objective: To determine if the leptin, adiponectin, and leptin/adiponectin ratio (LAR) can predict weight gain at the end of GnRH analogs (GnRHa) treatment in girls with central precocious puberty (CPP).: Material and methods: Study design: ... ...

Abstract	Objective: To determine if the leptin, adiponectin, and leptin/adiponectin ratio (LAR) can predict weight gain at the end of GnRH analogs (GnRHa) treatment in girls with central precocious puberty (CPP). Material and methods: Study design: prospective cohort. Serum levels of leptin and adiponectin were determined at diagnosis of CPP. Anthropometry was performed at diagnosis of CPP and every six-months, until treatment with GnRHa was discontinued and they presented menarche. Patients were divided according to BMI<94 and BMI>95 percentile at diagnosis of CPP. The outcome was the increased in weight gain (e.g., from normal weight to overweight) at the end of follow-up. Statistical analysis: repeated measures ANOVA test and Student's t-test were used to compare groups. Logistic regression analysis was used to evaluate the association of leptin and adiponectin levels, as well as LAR values with increased weight gain. Results: Fifty-six CPP patients were studied, 18 had BMI >95 percentile and 38 BMI <94 percentile. Of the 18 patients who initially had BMI >95 Conclusions: In patients with CPP, leptin levels and higher LAR values appear to be associated with significantly greater weight gain during GhRHa treatment, particularly in girls starting with BMI < 94 percentile.
MeSH term(s)	Female ; Humans ; Leptin ; Puberty, Precocious/complications ; Adiponectin ; Prognosis ; Overweight/complications ; Prospective Studies ; Body Mass Index ; Weight Gain
Chemical Substances	Leptin ; Adiponectin
Language	English
Publishing date	2023-03-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2023.1101399
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Risk factors for testicular adrenal rest tumors in pediatric patients with congenital adrenal hyperplasia.

Rivera-Hernandez, Aleida / Jimenez-Osorio, Monica / Rodríguez-Mencias, Josseline Patricia / Escamilla-Castañeda, Karene Mariela / Madrigal-Gonzalez, Monica Margarita / Zurita-Cruz, Jessie

Journal of pediatric urology

2023 Volume 19, Issue 4, Page(s) 398.e1–398.e7

Abstract: Introduction: Testicular adrenal rest tumors (TARTs) predominantly occur in patients with congenital adrenal hyperplasia (CAH) and may interfere with the function of the testicles.: Objective: This study aimed to identify the factors that contribute ... ...

Abstract	Introduction: Testicular adrenal rest tumors (TARTs) predominantly occur in patients with congenital adrenal hyperplasia (CAH) and may interfere with the function of the testicles. Objective: This study aimed to identify the factors that contribute to the occurrence of TARTs in patients with CAH and influence their volume. Study design: This was a comparative cross-sectional study. Male patients aged 0-16 years with CAH were included. Weight, height, bone age determination, biochemical and androgenic profiles, and testicular ultrasound were performed. Patients were divided into those with and without TARTs and the between-group differences were assessed using the Mann-Whitey U test and Fisher's exact test. A ROC curve was created for serum ACTH levels to identify the cut-off point to diagnose TARTs. Variables that influenced the volume of the TARTs were identified using Spearman's correlation coefficient. Results: TARTs were observed in seven (19.4%) of 36 male children with CAH. Of the patients with TARTs, 85.7% were pubertal. Serum concentrations of adrenocorticotropic hormone (ACTH) levels were significantly higher in patients with TARTs than in those without (309.0 pg/mL vs. 45.2 pg/mL; p = 0.006). ACTH levels >200 pg/mL were found to predict the presence of TARTs (sensitivity 85.7%; specificity 86.2%) (Figure). The factors found to correlate with TARTs volume were ACTH levels (coefficient 0.004; p = 0.009) and the three-year average of serum testosterone levels (coefficient 9.64; p = 0.003).] DISCUSSION: The main limitation of this study was the small sample size. However, an ACTH cut-off point to predict insufficient hormonal treatment and consequently the presence of TART had not been described. Conclusions: High ACTH (>200 pg/mL) was found to be predictive insufficient hormonal treatment in patients with CAH. The three-year average of serum testosterone levels and ACTH concentrations were correlated with the volume of TARTs.
MeSH term(s)	Humans ; Child ; Male ; Adrenal Hyperplasia, Congenital/complications ; Adrenal Hyperplasia, Congenital/pathology ; Adrenal Rest Tumor/etiology ; Adrenal Rest Tumor/pathology ; Cross-Sectional Studies ; Testicular Neoplasms/pathology ; Risk Factors ; Testosterone ; Adrenocorticotropic Hormone
Chemical Substances	Testosterone (3XMK78S47O) ; Adrenocorticotropic Hormone (9002-60-2)
Language	English
Publishing date	2023-03-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2237683-5
ISSN	1873-4898 ; 1477-5131
ISSN (online)	1873-4898
ISSN	1477-5131
DOI	10.1016/j.jpurol.2023.03.028
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6387: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Effect of the normalization of TSH and free T4 on lipid profile in a pediatric population with primary hypothyroidism.

Rivera-Hernández, Aleida / Rojas-Martínez, Raúl / Mendoza-Zubieta, Victoria / Balcázar-Hernández, Lourdes

Andes pediatrica : revista Chilena de pediatria

2021 Volume 92, Issue 1, Page(s) 59–66

Abstract: Introduction: Hypothyroidism has been associated with dyslipidemia. Its treatment with levothyroxine has shown a positive effect on the lipid profile in adults, however, there is a lack of data on the pediatric popu lation.: Objective: to evaluate ... ...

Title translation	Efecto de la normalización de TSH y T4 libre sobre el perfil lipídico en población pediátrica con hipotiroidismo primario.
Abstract	Introduction: Hypothyroidism has been associated with dyslipidemia. Its treatment with levothyroxine has shown a positive effect on the lipid profile in adults, however, there is a lack of data on the pediatric popu lation. Objective: to evaluate the effect of the thyroid profile normalization on the lipid profile in children with primary hypothyroidism. Patients and method: Retrospective study in children aged from 6 to 16 years, with diagnosis of primary hypothyroidism due to Hashimoto's thyroiditis, in treatment with levothyroxine, and who had an evaluation of serum lipids before and during their treatment. The lipid profile was evaluated in 2 stages: the first one referred to as "before levothyroxine treatment" (at the diagnosis of primary hypothyroidism) and the second one referred to as " thyroid profile normalization" (when normalization of Thyroid-stimulating hormone [TSH] and free T4 [FT4] was achieved during levothyroxine treatment). Sociodemographic and anthropometric data were recorded. The lipid profile evaluation consisted of the serum determination of total cholesterol (TC), high-density cholesterol (HDL-C), and TG. The phenotype of dyslipidemias was determined according to the Fredrickson's classification. Results: 72 patients were included (61% women; age 11.5 ± 2.9 years), out of which 58.3% (n = 42) presented pre-treatment dyslipidemia. In hypothyroid state, it was evident the correlation of TSH with TC (r = 0.36; p = 0.002), LDL-C (r = 0.46; p = 0.01), and HDL-C (r = -0.33; p = 0.004). The thyroid profile normalization showed the reduction of TC [184 mg/dL (IQR 92-322) vs 147 mg/dL (IQR 92-283); p = 0.05], LDL-C [99 mg/dL (IQR 44-232) vs 82 mg/dL (IQR 41-168); p = 0.02], TG [113 mg/dL (IQR 50-483) vs 88 mg/dL (IQR 16-343); p = 0.03], and the frequency of dyslipidemia [58.3% vs 22.2%; p = 0.001), as well as the TC correction with TG (r = 0.35; p = 0.02) and LDL-C (r = 0.88; p = 0.01). Persistent dyslipidemia was associated with obesity (r = 0.27; p = 0.02), overweight (r = 0.58; p = 0.001), and pre-treatment dyslipidemia (r = 0.53; p = 0.001). Conclusions: There is an association between TSH, TC, LDL-C, and HDL-C in hypothyroidism. When the thyroid profile was normalized, there was a reduction of TC, TG, LDL- C, and dyslipidemia frequency. Persistent dyslipidemia was associated with obesity, overweight, and pre-treatment dyslipidemia.
MeSH term(s)	Adolescent ; Child ; Cholesterol/blood ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Dyslipidemias/blood ; Dyslipidemias/classification ; Dyslipidemias/complications ; Female ; Hashimoto Disease/complications ; Humans ; Hypothyroidism/blood ; Hypothyroidism/drug therapy ; Hypothyroidism/etiology ; Lipids/blood ; Male ; Pediatric Obesity/etiology ; Reference Values ; Retrospective Studies ; Thyrotropin/blood ; Thyroxine/blood ; Thyroxine/therapeutic use ; Triglycerides/blood
Chemical Substances	Cholesterol, HDL ; Cholesterol, LDL ; Lipids ; Triglycerides ; Thyrotropin (9002-71-5) ; Cholesterol (97C5T2UQ7J) ; Thyroxine (Q51BO43MG4)
Language	Spanish
Publishing date	2021-02-22
Publishing country	Chile
Document type	Journal Article
ISSN	2452-6053
ISSN (online)	2452-6053
DOI	10.32641/andespediatr.v92i1.2614
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Van Wyk-Grumbach syndrome and trisomy 21.

Rivera-Hernández, Aleida / Madrigal-González, Mónica Margarita / Espinosa-Peniche, Rossana / Zurita-Cruz, Jessie / Balcázar-Hernández, Lourdes

Proceedings (Baylor University. Medical Center)

2022 Volume 35, Issue 4, Page(s) 569–571

Abstract: The Van Wyk-Grumbach syndrome (VWGS) is characterized by severe hypothyroidism, peripheral precocious puberty, delayed bone age, hyperestrogenism, prepubertal luteinizing hormone, and elevated follicle-stimulating hormone. Patients with Down syndrome ... ...

Abstract	The Van Wyk-Grumbach syndrome (VWGS) is characterized by severe hypothyroidism, peripheral precocious puberty, delayed bone age, hyperestrogenism, prepubertal luteinizing hormone, and elevated follicle-stimulating hormone. Patients with Down syndrome have a high susceptibility and prevalence of thyroid disorders. However, the coexistence of VWGS and trisomy 21 is uncommon. We present a case of a 5-year-old Mexican girl with Down syndrome, severe autoimmune hypothyroidism, pituitary enlargement, hyperprolactinemia, peripheral precocious puberty, multiple ovarian cysts, and delayed bone age, with a clinical diagnosis of VWGS. The patient presented with a remission of these manifestations after treatment with levothyroxine. Patients with Down syndrome, precocious puberty, hyperestrogenism, prepuberal luteinizing hormone, high follicle-stimulating hormone, and delayed bone age should be evaluated with a thyroid profile due to the possibility of VWGS.
Language	English
Publishing date	2022-03-24
Publishing country	United States
Document type	Case Reports
ZDB-ID	2703932-8
ISSN	1525-3252 ; 0899-8280
ISSN (online)	1525-3252
ISSN	0899-8280
DOI	10.1080/08998280.2022.2054048
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6987: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Novel pathogenic variant of

Rivera-Hernández, Aleida / Madrigal-González, Mónica / Mejía-Carmona, Luz / Martínez-López, Isis / Pérez-Hernández, María Guadalupe / Bernal-Manjarrez, Joaquín / Luna-Vidal, Sergio / Reta-Guerrero, Sarahí / Rodríguez-Florido, Marco Antonio / Balcázar-Hernández, Lourdes

Journal of pediatric endocrinology & metabolism : JPEM

2023 Volume 36, Issue 8, Page(s) 782–785

Abstract: Objectives: To present a case of a new pathogenic variant of DICER1.: Case presentation: 13-year-old female with non-toxic multinodular goiter and ovarian Sertoli-Leydig cell tumor, in whom a pineal parenchymal tumor of intermediate differentiation ... ...

Abstract	Objectives: To present a case of a new pathogenic variant of DICER1. Case presentation: 13-year-old female with non-toxic multinodular goiter and ovarian Sertoli-Leydig cell tumor, in whom a pineal parenchymal tumor of intermediate differentiation was diagnosed. Next-generation sequencing revealed a new germline mutation in the Conclusions: Mutations in the
MeSH term(s)	Male ; Female ; Humans ; Adolescent ; Child ; Young Adult ; Sertoli-Leydig Cell Tumor/genetics ; Sertoli-Leydig Cell Tumor/pathology ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/pathology ; Pinealoma ; Goiter ; Brain Neoplasms ; Pineal Gland/pathology ; Cell Differentiation/genetics ; Ribonuclease III/genetics ; DEAD-box RNA Helicases/genetics
Chemical Substances	DICER1 protein, human (EC 3.1.26.3) ; Ribonuclease III (EC 3.1.26.3) ; DEAD-box RNA Helicases (EC 3.6.4.13)
Language	English
Publishing date	2023-06-13
Publishing country	Germany
Document type	Case Reports
ZDB-ID	1231070-0
ISSN	2191-0251 ; 0334-018X
ISSN (online)	2191-0251
ISSN	0334-018X
DOI	10.1515/jpem-2023-0149
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2258: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Disfunción tiroidea por I131-Metayodo Benzilguanidina en pacientes con neuroblastoma.

Garrido Magaña, Eulalia / Silva Estrada, Jorge Alberto / Nishimura Meguro, Elisa / Rivera Hernández, Aleida de Jesús / Zurita Cruz, Jessie Nallely

Revista chilena de pediatria

2020 Volume 91, Issue 3, Page(s) 379–384

Abstract: Introduction: The treatment of advanced neuroblastoma includes chemotherapy, surgery, and radiotherapy with 131-I-Metaiodobenzylguanidine (131-I-MIBG). Despite strategies to protect thyroid function, its dysfunction is reported between 12 and 85%.: ... ...

Title translation	Thyroid dysfunction due to 131I-metaiodobenzylguanidine in patients with neuroblastoma.
Abstract	Introduction: The treatment of advanced neuroblastoma includes chemotherapy, surgery, and radiotherapy with 131-I-Metaiodobenzylguanidine (131-I-MIBG). Despite strategies to protect thyroid function, its dysfunction is reported between 12 and 85%. Objective: To identify the frequency of thyroid dys function in cases of neuroblastoma treated with 131-I-MIBG. Patients and method: Cross-sectional study. We included all the cases with neuroblastoma treated with 131-I-MIBG between 2002 and 2015, with complete somatometry, and complete thyroid profile (TSH, free and total T3 and T4, and anti-thyroglobulin and antiperoxidase antibodies). Results: 27 patients were identified out of which eleven died (40%). Out of the 16 surviving cases, 9 (56%) presented thyroid dysfunction: 2 (13%) cases with subclinical hypothyroidism and 7 (44%) cases with clinical hypothyroidism (3 cases due to psychomotor developmental delay and 4 due to growth deceleration). The patients presented cli nical manifestations at 16.1 months (1.2-66.3 months) after receiving the radiopharmaceutical at a cumulative dose of 142 mCi (96-391.5 mCi). No differences were found in the age at diagnosis, age at the start of treatment with 131-I-MIBG, the cumulative dose of 131-I-MIBG, and the time elapsed between the dose and the thyroid profile among the cases with or without thyroid dysfunction. Con clusions: 56% of patients with neuroblastoma had thyroid dysfunction. Most of the cases with hy pothyroidism were referred when thyroid dysfunction was clinically evident. A thyroid profile should be performed every 6 months, along with an annual endocrinological evaluation during the next 5 years in these patients.
MeSH term(s)	3-Iodobenzylguanidine/adverse effects ; 3-Iodobenzylguanidine/therapeutic use ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Hypothyroidism/diagnosis ; Hypothyroidism/epidemiology ; Hypothyroidism/etiology ; Infant ; Iodine Radioisotopes/adverse effects ; Iodine Radioisotopes/therapeutic use ; Male ; Neuroblastoma/radiotherapy ; Radiopharmaceuticals/adverse effects ; Radiopharmaceuticals/therapeutic use ; Retrospective Studies ; Risk Factors ; Thyroid Diseases
Chemical Substances	Iodine Radioisotopes ; Iodine-131 ; Radiopharmaceuticals ; 3-Iodobenzylguanidine (35MRW7B4AD)
Language	Spanish
Publishing date	2020-07-29
Publishing country	Chile
Document type	Journal Article
ZDB-ID	954077-5
ISSN	0717-6228 ; 0034-7396 ; 0370-4106
ISSN (online)	0717-6228
ISSN	0034-7396 ; 0370-4106
DOI	10.32641/rchped.v91i3.1237
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 406: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Altered cardiometabolic profile in girls with central precocious puberty and adipokines: A propensity score matching analysis.

Zurita-Cruz, Jessie N / Villasís-Keever, Miguel A / Manuel-Apolinar, Leticia / Damasio-Santana, Leticia / Gutierrez-Gonzalez, Alejandro / Wakida-Kusunoki, Guillermo / Padilla-Rojas, Michel / Maldonado-Rivera, Cesar / Garrido-Magaña, Eulalia / Rivera-Hernández, Aleida de J / Nishimura-Meguro, Elisa

Cytokine

2021 Volume 148, Page(s) 155660

Abstract: Objective: To compare cardiometabolic factors and adipokines between patients with recently diagnosed CPP and controls without CPP, paired by BMI Z scores (BMIz) and classified into girls with adequate nutritional status and girls who are overweight or ... ...

Abstract	Objective: To compare cardiometabolic factors and adipokines between patients with recently diagnosed CPP and controls without CPP, paired by BMI Z scores (BMIz) and classified into girls with adequate nutritional status and girls who are overweight or obese. Methods: This cross-sectional study was performed from January 2012 to May 2015 at two tertiary care pediatric centers in Mexico City. We included female patients with idiopathic CPP without other chronic pathology and healthy controls. Patients were divided into groups, BMI < 85th and BMI ≥ 85th percentile, according to 2000 CDC Growth Charts. Anthropometric data and fasting plasma concentrations of lipids, glucose, insulin, and leptin were assessed. Results: There were 73 patients with CPP and 82 without CPP. Sixty-six patients were matched between the groups; no significant difference was noted between the groups according to zBMI. However, differences in the bone/chronological age relationship, birth weight and proportions in different Tanner stages were observed. Among girls with normal BMI, the percentage of body fat (24.6% vs 18.9%, p < 0.001), serum triglycerides (102.9 vs 54.3 mg/dl, p < 0.001), leptin (7.46 vs 5.4 ng/ml, p = 0.010) and free leptin (0.44 vs 0.29 ng/ml, p = 0.044) were higher in those with CPP; additionally, girls with CPP presented a higher proportion of hypertriglyceridemia. In the overweight/obese group, adiponectin levels were lower in girls with CPP (6.23 vs 7.28 pg/ml, p = 0.011). Conclusions: Girls with CPP and normal BMI at diagnosis had a worse cardiometabolic profile, as reflected by higher levels of free leptin, and higher proportion of hypertriglyceridemia than girls without CPP.
MeSH term(s)	Adipokines/blood ; Child ; Female ; Humans ; Lipids/blood ; Myocardium/metabolism ; Propensity Score ; Puberty, Precocious/blood
Chemical Substances	Adipokines ; Lipids
Language	English
Publishing date	2021-07-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1018055-2
ISSN	1096-0023 ; 1043-4666
ISSN (online)	1096-0023
ISSN	1043-4666
DOI	10.1016/j.cyto.2021.155660
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2840: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pediatric patients with type 1-diabetes: growth and growth failure associated factors

Zurita Cruz, Jessie Nallely / Dosta Martínez, Gabriela Esthephania / Villasís Keever, Miguel Ángel / Rivera Hernández, Aleida de Jesús / Garrido Magaña, Eulalia / Nishimura Meguro, Elisa

Hospital Infantil de México Federico Gómez Boletín Médico del Hospital Infantil de México (English Edition). 2016,

2016

Abstract: Type 1 diabetes (T1D) usually occurs in the pediatric age and affects the growth of children. The aim of this work was to describe growth and growth failure associated factors in a population of children with T1D in a tertiary level pediatric hospital.A ... ...

Abstract	Type 1 diabetes (T1D) usually occurs in the pediatric age and affects the growth of children. The aim of this work was to describe growth and growth failure associated factors in a population of children with T1D in a tertiary level pediatric hospital.A case-control nested in a cohort study was conducted. We included patients with T1D under 16 years of age with a minimum follow-up of 12 months. Data as age at T1D diagnosis, anthropometry, glycated hemoglobin (HbA1c), as well as the pubertal development (Tanner stage) were collected at the time of diagnosis and during four years of follow-up. At the end of the follow-up, patients with and without growth failure were compared, and matched by sex and age at T1D diagnosis. Univariate and multivariate analyses were performed.On the first year of follow-up, 95 patients were gathered; 88 patients were still followed-up by the second year, 56 patients were kept for the third year, and 46 patients were still followed-up by the fourth year. Median age was 9.5 years, and 50% were preadolescents. During their evolution, 50% had growth failure. According to the multivariate analysis, the factor associated with growth failure was the HbA1c in the first year post-diagnosis (OR 4.08; 95% CI 1.34-12.42).In the first year post-diagnosis of children with T1D, HbA1c was associated with growth failure.
Keywords	Type 1 diabetes ; Growth ; Child. ; Diabetes mellitus tipo 1 ; Crecimiento ; Niños
Language	English
Publishing place	Masson Doyma México S.A.
Document type	Article ; Online
Note	Pre-press version
ISSN	2444-3409
DOI	10.1016/j.bmhime.2016.03.001
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED