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Article ; Online: The Modified Stenver’s View for Cochlear Implants – What do the Surgeons Want to Know?

Fiona McClenaghan / Robert Nash

Journal of the Belgian Society of Radiology, Vol 104, Iss

2020 Volume 1

Abstract: Despite developments in electrophysiological testing, imaging remains the standard method to determine cochlear implant positioning. Whilst cone beam computed tomography is optimal, modified Stenver radiographs are easier to perform and are therefore ... ...

Abstract	Despite developments in electrophysiological testing, imaging remains the standard method to determine cochlear implant positioning. Whilst cone beam computed tomography is optimal, modified Stenver radiographs are easier to perform and are therefore commonly used. With recent debate as to the need for routine imaging in uncomplicated cases, the radiologist is increasingly faced with cases of abnormal anatomy or surgical error. The primary interest is the positioning of the electrode array within the cochlea. This includes evidence of tip roll over or kinking and depth of electrode insertion, as both are independent predictors of hearing outcomes and may necessitate revision surgery.
Keywords	cochlear implant ; hearing rehabilitation ; modified stenver’s radiograph ; otorhinolaryngology ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	Ubiquity Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Anatomy and Development of the Mammalian External Auditory Canal

Mona Mozaffari / Robert Nash / Abigail S. Tucker

Frontiers in Cell and Developmental Biology, Vol

Implications for Understanding Canal Disease and Deformity

2021 Volume 8

Abstract: The mammalian ear is made up of three parts (the outer, middle, and inner ear), which work together to transmit sound waves into neuronal signals perceived by our auditory cortex as sound. This review focuses on the often-neglected outer ear, ... ...

Abstract	The mammalian ear is made up of three parts (the outer, middle, and inner ear), which work together to transmit sound waves into neuronal signals perceived by our auditory cortex as sound. This review focuses on the often-neglected outer ear, specifically the external auditory meatus (EAM), or ear canal. Within our complex hearing pathway, the ear canal is responsible for funneling sound waves toward the tympanic membrane (ear drum) and into the middle ear, and as such is a physical link between the tympanic membrane and the outside world. Unique anatomical adaptations, such as its migrating epithelium and cerumen glands, equip the ear canal for its function as both a conduit and a cul-de-sac. Defects in development, or later blockages in the canal, lead to congenital or acquired conductive hearing loss. Recent studies have built on decades-old knowledge of ear canal development and suggest a novel multi-stage, complex and integrated system of development, helping to explain the mechanisms underlying congenital canal atresia and stenosis. Here we review our current understanding of ear canal development; how this biological lumen is made; what determines its location; and how its structure is maintained throughout life. Together this knowledge allows clinical questions to be approached from a developmental biology perspective.
Keywords	hearing ; deafness ; external ear ; ear canal ; ear deformities ; congenital ; Biology (General) ; QH301-705.5
Subject code	390 ; 780
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book: Alcohol and homicide

Parker, Robert Nash / Rebhun, Linda-Anne

a deadly combination of two American traditions

(SUNY Series in violence)

1995

Author's details	Robert Nash Parker with Linda-Anne Rebhun
Series title	SUNY Series in violence
Keywords	Alcoholic Beverages / adverse effects ; Alcoholism / history / United States ; Homicide / prevention & control / United States ; USA ; Alkoholismus ; Tötung
Subject	Gewaltsamer Tod ; Tötungsdelikt ; Töten ; Alkoholabhängigkeit ; Trunksucht ; Alkoholbedingte Krankheit ; Alkoholkrankheit ; Alkoholsucht ; Alkohol
Language	English
Size	XXIII, 185 S. : graph. Darst.
Publisher	State Univ. of New York Press
Publishing place	Albany, NY
Publishing country	United States
Document type	Book
HBZ-ID	HT007392354
ISBN	0-7914-2463-4 ; 978-0-7914-2463-6
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

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1997 A 342	order for loan	Magazin

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Article: Alcohol and violence: connections, evidence and possibilities for prevention.

Parker, Robert Nash

Journal of psychoactive drugs

2004 Volume Suppl 2, Page(s) 157–163

Abstract: This article reviews a number of theoretical and substantive arguments and models concerning the link between alcohol and violent crime which have appeared in the research literature in the past decade. These arguments and models form a firm foundation ... ...

Abstract	This article reviews a number of theoretical and substantive arguments and models concerning the link between alcohol and violent crime which have appeared in the research literature in the past decade. These arguments and models form a firm foundation for the expectation that alcohol plays a causal role in violent crime, and that interventions designed to reduce or eliminate this link between alcohol and violence have the potential to become effective violence prevention policies. Four studies on the relationship between alcohol and violence are summarized, including one in which a natural alcohol policy experiment is evaluated. Taken together, these studies provide substantial empirical evidence that alcohol policy can be an effective crime prevention tool.
MeSH term(s)	Alcohol Drinking/adverse effects ; Alcohol Drinking/prevention & control ; Alcohol Drinking/psychology ; Alcoholic Beverages/adverse effects ; Humans ; Public Policy ; United States ; Violence/prevention & control ; Violence/statistics & numerical data ; Violence/trends
Language	English
Publishing date	2004-07-20
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	392405-1
ISSN	2159-9777 ; 0279-1072
ISSN (online)	2159-9777
ISSN	0279-1072
DOI	10.1080/02791072.2004.10400051
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Butterflies Extracts Show Antibacterial Activity

Rasooly, Reuven / Miriam Rothschild / Yael Gov / Paul Wolferstan / Robert Nash / Paula Do / Naomi Balaban

Advances in Microbiology. 2017 June 20, v. 7, no. 06

2017

Abstract: Extracts of several British butterfly species were tested and shown to possess powerful bactericidal activity against gram-positive bacteria (tested on Staphylococcus aureus and Bacillus anthracis). The active compounds in the grass-feeding species were ... ...

Abstract	Extracts of several British butterfly species were tested and shown to possess powerful bactericidal activity against gram-positive bacteria (tested on Staphylococcus aureus and Bacillus anthracis). The active compounds in the grass-feeding species were identified as hydroxylated pyrrolizidine alkaloids (PAs) related to loline with nitrogen at C-1. Lolines are known insecticidal and insect-deterrent compounds that are produced in grasses infected by endophytic fungal symbionts. Lolines also increase resistance of endophyte-infected grasses to insect herbivores. The butterfly-isolated pyrrolizidine alkaloids appear to be novel and non-toxic to human cells such as HaCat human skin keratinocytes and Hep-2 human epithelial cells. The discovery of novel agents from butterflies could lead to the development of new antimicrobials.
Keywords	Bacillus anthracis ; Gram-positive bacteria ; Staphylococcus aureus ; active ingredients ; anti-infective agents ; antibacterial properties ; butterflies ; endophytes ; epithelial cells ; fungi ; grasses ; humans ; keratinocytes ; pyrrolizidine alkaloids ; symbionts ; United Kingdom
Language	English
Dates of publication	2017-0620
Size	p. 467-479.
Document type	Article
ZDB-ID	2681313-0
ISSN	2165-3410 ; 2165-3402
ISSN (online)	2165-3410
ISSN	2165-3402
DOI	10.4236/aim.2017.76036
Database	NAL-Catalogue (AGRICOLA)

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Article: Anti-inflammatory properties of an extract of M. ilicifolia in the human intestinal epithelial Caco-2 cell line

Wonfor, Ruth / Deborah Nash / Ifat Parveen / Manfred Beckman / Manuela Natoli / Robert Nash

Journal of ethnopharmacology. 2017 Sept. 14, v. 209

2017

Abstract: Maytenus ilicifolia is a Celastracea plant used in traditional medicine to alleviate digestive tract inflammatory disorders.We investigated anti-inflammatory properties of M. ilicifolia crude extract towards Caco-2 cell line, as a model of Toll-like ... ...

Abstract	Maytenus ilicifolia is a Celastracea plant used in traditional medicine to alleviate digestive tract inflammatory disorders.We investigated anti-inflammatory properties of M. ilicifolia crude extract towards Caco-2 cell line, as a model of Toll-like Receptor 2 (TLR-2) inflammatory pathway.Toxicity was assessed following culture of Caco-2 with M. ilicifolia, using apparent cell permeability and trans-epithelial electric resistance. Anti-inflammatory properties of M. ilicifolia were assessed through IL-8 secretion and TLR-2 associated gene expression of Caco-2 cells with or without an LTA challenge.M. ilicifolia was not toxic to Caco-2 cells. M. ilicifolia down-regulated TLR2 expression with and without LTA challenge but had no effect on other genes. Following LTA challenge of Caco-2 cells, 100 and 200μg/mL M. ilicifolia abrogated IL-8 secretion.We provide preliminary data for some M. ilicifolia anti-inflammatory properties. Further research must establish the full extent and mode of action on particular inflammatory pathways.
Keywords	anti-inflammatory activity ; digestive tract ; electrical resistance ; epithelium ; gene expression regulation ; genes ; human cell lines ; humans ; interleukin-8 ; Maytenus ilicifolia ; mechanism of action ; models ; permeability ; secretion ; Toll-like receptor 2 ; toxicity ; traditional medicine
Language	English
Dates of publication	2017-0914
Size	p. 283-287.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2017.08.006
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

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Article ; Online: Non-echoplanar diffusion weighted imaging in the detection of post-operative middle ear cholesteatoma

Ravi K. Lingam / Robert Nash / Anooj Majithia / Ali Kalan / Arvind Singh

Insights into Imaging, Vol 7, Iss 5, Pp 669-

navigating beyond the pitfalls to find the pearl

2016 Volume 678

Abstract: Abstract Non-echoplanar diffusion weighted magnetic resonance imaging (DWI) has established itself as the modality of choice in detecting and localising post-operative middle ear cleft cholesteatoma. Despite its good diagnostic performance, there are ... ...

Abstract	Abstract Non-echoplanar diffusion weighted magnetic resonance imaging (DWI) has established itself as the modality of choice in detecting and localising post-operative middle ear cleft cholesteatoma. Despite its good diagnostic performance, there are recognised pitfalls in its radiological interpretation which both the radiologist and otologist should be aware of. Our article highlights the various pitfalls and provides guidance for improving radiological interpretation and navigating beyond many of the pitfalls. It is recommended radiological practice to interpret the diffusion weighted images together with the ADC map and supplement with the corresponding T1 weighted and T2 weighted images, all of which can contribute to and enhance lesion localisation and characterisation. ADC values are also helpful in improving specificity and confidence levels. Given the limitation in sensitivity in detecting small cholesteatoma less than 3 mm, serial monitoring with DWI over time is recommended to allow any small residual cholesteatoma pearls to grow and become large enough to be detected on DWI. Optimising image acquisition and discussing at a joint clinico-radiological meeting both foster good radiological interpretation to navigate beyond the pitfalls and ultimately good patient care. Teaching Points • Non-echoplanar DWI is the imaging of choice in detecting post-operative cholesteatoma. • There are recognised pitfalls which may hinder accurate radiological interpretation. • Interpret with the ADC map /values and T1W and T2W images. • Serial DWI monitoring is of value in detection and characterisation. • Optimising image acquisition and discussing at clinico-radiological meetings enhance radiological interpretation.
Keywords	Diffusion weighted imaging ; MRI ; Cholesteatoma ; Pitfalls ; DWI ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2016-08-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book: Alcohol and violence

Parker, Robert Nash / McCaffree, Kevin J

the nature of the relationship and the promise of prevention

2013

Abstract: Many people have experienced or witnessed situations in which people drinking alcohol get aggressive, obnoxious, and violent. Scientific research has shown evidence of a relationship between alcohol and violence, and even evidence that alcohol plays a ... ...

Author's details	Robert Nash Parker and Kevin J. McCaffree
Abstract	"Many people have experienced or witnessed situations in which people drinking alcohol get aggressive, obnoxious, and violent. Scientific research has shown evidence of a relationship between alcohol and violence, and even evidence that alcohol plays a role in causing violent and aggressive responses. The book explores a number of aspects of this relationship. If you have been drinking are you more likely to be a victim of crime? If victimized, does drinking alcohol make you more likely to be injured? How does availability of alcohol in the community influence rates of violence among Mexican American youth? Does advertising that links sex and alcohol result in higher rates of sexual assault in Latino neighborhoods? How do elementary school children react to experimentation with drugs, alcohol, and aggression? Do countries outside the US have alcohol and violence problems, and do these impact men and women differently? We presents original research that shows the depths and conditions under which alcohol and violence are linked, further strengthening the evidence that alcohol use and availability is an important factor in violence in our cities, neighborhoods, school, and homes. The good news is that we regulate alcohol use and availability effectively, with a body of established laws and procedures. We can, therefore, find ways using this existing system to develop new ways to prevent the alcohol related violence studied here. The second half of the book begins this task by laying out the principles of environmental prevention, a strategy that has been very successful in a number of health and safety related domains. The next four chapters show just how environmental prevention strategies have worked, and worked very effectively, to lower rates of violence by reducing alcohol availability and alcohol consumption. The research reported here shows communities different approaches and mechanisms to achieve reductions in violence, and they provide a road map for communities everywhere to follow suit and reduce alcohol related violence. Reducing violence can be accomplished, everyone can do it if they work together, and the result is a safer and better society."--Publisher's website.
MeSH term(s)	Alcohol Drinking ; Violence/prevention & control
Keywords	United States
Language	English
Size	xviii, 211 p. :, ill. ;, 23 cm.
Publisher	Lexington Books
Publishing place	Lanham
Document type	Book
ISBN	9780739180112 ; 0739180118 ; 9780739180129 ; 0739180126
Database	Catalogue of the US National Library of Medicine (NLM)

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Book ; Online: Alcohol and violence

Parker, Robert Nash / McCaffree, Kevin J

the nature of the relationship and the promise of prevention

2013

Abstract: This book interrogates new contexts of the alcohol and violence relationship: victimization and injury, Mexican-American youth, elementary school children, advertising, and cross national comparisons. Environmental prevention strategies are deployed ... ...

Institution	ebrary, Inc
Author's details	Robert Nash Parker and Kevin J. McCaffree
Abstract	This book interrogates new contexts of the alcohol and violence relationship: victimization and injury, Mexican-American youth, elementary school children, advertising, and cross national comparisons. Environmental prevention strategies are deployed towards harm reduction in the alcohol and violence framework. Minimum drinking age increases, extreme and moderate reductions in availability, and direct community based efforts in enforcement and reduced consumption are successfully employed in real communities to show that it is possible to reduce alcohol related violence.</span<br />
Keywords	Alcoholism and crime ; Violent crimes ; Violent crimes/Prevention
Language	English
Size	Online-Ressource (xviii, 211 p)
Publisher	Lexington Books
Publishing place	Lanham, MD
Document type	Book ; Online
Note	Includes bibliographical references and index
ISBN	9780739180112 ; 0739180118
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomera™) on body weight and lipid parameters of healthy overweight participants

Boris Azantsa / Dieudonne Kuate / Raoul Chakokam / Ghislain Paka / Barbara Bartholomew / Robert Nash

Functional Foods in Health and Disease, Vol 5, Iss 6, Pp 200-

2015 Volume 208

Abstract: Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Considering the physio-metabolic changes that accompany obesity, the present ... ...

Abstract	Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Considering the physio-metabolic changes that accompany obesity, the present study investigates the effects of these extracts on healthy overweight participants over an 8-week test period. Methods: The study was an 8 week randomized double-blind, placebo controlled design involving 48 overweight (BMI 26 – 30) participants (27 females and 19 males), divided into 3 groups – placebo, 300 mg I. gabonensis extract (IGOB131), or 300 mg D. glomerata extract (DyglomeraTM). Capsules containing the placebo or the test formulations were administered once daily before the main meal of the day. No major dietary changes or changes in physical activity were demonstrated during the study. Weight and blood lipid parameters were measured at baseline, and at the 4 and 8 weeks interval. Results: Compared to the placebo group, there were significant (p<0.05) reductions in weight of participants in both test groups over the 8 week period. However, these significant changes were not observed in the initial 4 weeks, even though the lipid parameters in the test groups changed significantly (p<0.05). Conclusion: The extracts of Irvingia gabonensis and Dichrostachys glomerata, at a dose of 300 mg per day, were effective in reducing weight and positively modifying lipid parameters in healthy overweight participants.
Keywords	Overweight ; Dichrostachys ; Irvingia ; waist-hip circumference ; blood lipids ; Nutrition. Foods and food supply ; TX341-641 ; Medicine (General) ; R5-920
Subject code	796
Language	English
Publishing date	2015-06-01T00:00:00Z
Publisher	Food Science Publisher
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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