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  1. Article ; Online: The Role of Content Experts in Appropriate Use Criteria: Commentary on an article by Alexander J. Acuña, BS, et al.: "Industry Payments Among Appropriate Use Criteria Voting Panels. An Open Payments Analysis".

    Roberts, Karl C / Chen, Antonia F / Quinn, Robert

    The Journal of bone and joint surgery. American volume

    2022  Volume 104, Issue 4, Page(s) e14

    MeSH term(s) Conflict of Interest ; Humans ; Industry ; Politics
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.21.01136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Guide to optimizing care for Muslim patients with knee osteoarthritis.

    Haque, Mahfujul Z / Virk, Usman / Suhrawardy, Ameen / Roberts, Karl C / Magrey, Marina N

    Arthritis & rheumatology (Hoboken, N.J.)

    2023  Volume 75, Issue 4, Page(s) 641–642

    MeSH term(s) Humans ; Osteoarthritis, Knee/surgery ; Islam ; Arthroplasty, Replacement, Knee
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Letter
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Reduction in Opioid Prescription Size After Total Joint Arthroplasty Can be Safely Performed Without an Increase in Complications.

    Wenzlick, Thomas S / Kutzner, Andrew R / Markel, David C / Hughes, Richard E / Chubb, Heather D / Roberts, Karl C

    The Journal of arthroplasty

    2023  Volume 38, Issue 7, Page(s) 1245–1250

    Abstract: Background: Excessive opioid prescriptions after total joint arthroplasty (TJA) increase risks for adverse opioid-related events, chronic opioid use, and unlawful opioid diversion. Decreasing postoperative prescriptions may improve quality after TJA. ... ...

    Abstract Background: Excessive opioid prescriptions after total joint arthroplasty (TJA) increase risks for adverse opioid-related events, chronic opioid use, and unlawful opioid diversion. Decreasing postoperative prescriptions may improve quality after TJA. Concerns exist that a decrease in opioids prescribed may increase complications, such as readmissions, emergency department (ED) visits, or worsened patient-reported outcomes (PROs). The purpose of this study was to explore whether a reduction in opioids prescribed after TJA resulted in increased complications.
    Methods: Data originated from a statewide database prospectively abstracted, including oral morphine equivalents prescribed at discharge, readmissions, ED visits, and PROs. Data were collected from 84,998 TJA occurring 1 year before and after the creation of an opioid-prescribing protocol that had decreased prescriptions by approximately 50%. Trends were monitored using Shewhart control charts. Regression models were used to determine statistically significant changes over time.
    Results: All groups showed a reduction in opioids prescribed by almost 50% without an increase in emergency room visits or readmissions and without a detrimental effect on PROs. Compared to baseline data before opioid reduction, opioid-naive total knee arthroplasty had significant improvements in all outcomes (P = .03, P = .02, P < .001, P < .001). Opioid-tolerant total knee arthroplasty and total hip arthroplasty had no worsened outcomes and significant improvement in (Knee Injury and Osteoarthritis Outcome score for Joint Replacement P = .03) and (Hip Disability and Osteoarthritis Outcome Score for Joint Replacement P = .03). Opioid-naive total hip arthroplasty had significant improvements in Hip Disability and Osteoarthritis Outcome Score Joint Replacement (P = .003) and Patient Reported Outcomes Measurement Information System (P = .001).
    Conclusions: Postoperative opioid prescription recommendations from a statewide registry decreased prescribing by approximately 50% without decreasing PROs or increasing ED visits or readmissions. A reduction in opioids prescribed after TJA can be accomplished safely and without increased complications.
    MeSH term(s) Humans ; Analgesics, Opioid/therapeutic use ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Arthroplasty, Replacement, Knee/adverse effects ; Arthroplasty, Replacement, Hip/adverse effects ; Osteoarthritis/complications ; Prescriptions ; Retrospective Studies
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2023.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Public Interest in Hyaluronic Acid Injections for Knee Osteoarthritis in the United States and Europe: An International Google Trends Analysis.

    Cohen, Samuel A / Brophy, Robert H / Chen, Antonia F / Roberts, Karl C / Quinn, Robert H / Shea, Kevin G

    Arthroplasty today

    2022  Volume 18, Page(s) 157–162

    Abstract: Background: Hyaluronic acid injections remain a common nonsurgical alternative for the treatment of knee osteoarthritis despite limited clinical evidence and varying global recommendations regarding its use. We used the Google Trends tool to provide a ... ...

    Abstract Background: Hyaluronic acid injections remain a common nonsurgical alternative for the treatment of knee osteoarthritis despite limited clinical evidence and varying global recommendations regarding its use. We used the Google Trends tool to provide a quantitative analysis of public interest in hyaluronic acid injections for knee osteoarthritis in the United States and Europe.
    Methods: We customized Google Trends parameters to obtain search data from January 2009 to December 2019 in both the United States and Europe. Combinations of "arthritis", "osteoarthritis", "hyaluronic acid", "knee arthritis", "knee osteoarthritis", and "knee injection" were entered into the Google Trends tool, and trend analyses were performed.
    Results: The models generated to describe public interest in hyaluronic acid for knee injections in both the United States and Europe showed increased Google queries as time progressed (
    Conclusions: Our results indicate a significant increase in Google queries related to hyaluronic acid injections for knee osteoarthritis since 2009 in both the United States and Europe. Our models suggest that despite mixed evidence supporting its use, orthopedic surgeons should expect continued public interest in hyaluronic acid for knee osteoarthritis. The results of our study may help to prepare surgeons for patient inquiries, inform the creation of evidence-based shared decision-making tools, and direct future research.
    Language English
    Publishing date 2022-11-02
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2022.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: From evidence to application: AAOS clinical practice guideline on management of hip fractures in the elderly.

    Roberts, Karl C / Brox, W Timothy

    Journal of orthopaedic trauma

    2015  Volume 29, Issue 3, Page(s) 119–120

    MeSH term(s) Aged ; Aged, 80 and over ; Hip Fractures/surgery ; Hip Fractures/therapy ; Humans ; Practice Guidelines as Topic/standards
    Language English
    Publishing date 2015-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 639099-7
    ISSN 1531-2291 ; 0890-5339
    ISSN (online) 1531-2291
    ISSN 0890-5339
    DOI 10.1097/BOT.0000000000000272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: AAOS Clinical Practice Guideline: Management of Hip Fractures in the Elderly.

    Roberts, Karl C / Brox, W Timothy

    The Journal of the American Academy of Orthopaedic Surgeons

    2015  Volume 23, Issue 2, Page(s) 138–140

    MeSH term(s) Aged, 80 and over ; Disease Management ; Female ; Hemiarthroplasty/methods ; Hemiarthroplasty/standards ; Hip Fractures/diagnostic imaging ; Hip Fractures/surgery ; Humans ; Practice Guidelines as Topic ; Radiography ; Societies, Medical ; United States
    Language English
    Publishing date 2015-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-14-00433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nonsteroidal Anti-Inflammatory Drugs in Total Joint Arthroplasty: The Clinical Practice Guidelines of the American Association of Hip and Knee Surgeons, American Society of Regional Anesthesia and Pain Medicine, American Academy of Orthopaedic Surgeons, Hip Society, and Knee Society.

    Fillingham, Yale A / Hannon, Charles P / Roberts, Karl C / Hamilton, William G / Della Valle, Craig J

    The Journal of arthroplasty

    2020  Volume 35, Issue 10, Page(s) 2704–2708

    Language English
    Publishing date 2020-05-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2020.05.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Rim Fracture of a Tibial Base-Plate Due to Retained Cement as a Cause of Catastrophic Failure of Unicompartmental Knee Arthroplasty: A Case Report.

    Sawatzke, Alexander B / Bollinger, Alexander J / Butler, Paul D / Roberts, Karl C

    JBJS case connector

    2017  Volume 6, Issue 3, Page(s) e73

    Abstract: Case: We report a case of catastrophic implant failure due to fatigue fracture of a well-functioning unicompartmental knee arthroplasty at 7 years in an active 55-year-old man, who presented with sudden onset of atraumatic knee pain and effusion. The ... ...

    Abstract Case: We report a case of catastrophic implant failure due to fatigue fracture of a well-functioning unicompartmental knee arthroplasty at 7 years in an active 55-year-old man, who presented with sudden onset of atraumatic knee pain and effusion. The patient underwent revision to total knee arthroplasty. Intraoperative findings included a metallic fragment fractured off the rim of the tibial base-plate and cement retained in the tibial tray.
    Conclusion: Retained cement in the tibial tray resulted in increased tibial tray contact stresses and fatigue fracture of the rim of the tray, creating a free metallic loose body that produced symptoms.
    MeSH term(s) Arthroplasty, Replacement, Knee/instrumentation ; Humans ; Knee Prosthesis/adverse effects ; Male ; Middle Aged ; Prosthesis Failure/etiology
    Language English
    Publishing date 2017-11-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI 10.2106/JBJS.CC.15.00131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Efficacy and Safety of Nonsteroidal Anti-Inflammatory Drugs in Total Joint Arthroplasty: Systematic Review and Direct Meta-Analysis.

    Fillingham, Yale A / Hannon, Charles P / Roberts, Karl C / Mullen, Kyle / Casambre, Francisco / Riley, Connor / Hamilton, William G / Della Valle, Craig J

    The Journal of arthroplasty

    2020  Volume 35, Issue 10, Page(s) 2739–2758

    Abstract: Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have become widely used to manage perioperative pain following total joint arthroplasty (TJA). The purpose of our study is to evaluate the efficacy and safety of NSAIDs in support of the combined ...

    Abstract Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have become widely used to manage perioperative pain following total joint arthroplasty (TJA). The purpose of our study is to evaluate the efficacy and safety of NSAIDs in support of the combined clinical practice guidelines of the American Association of Hip and Knee Surgeons, American Academy of Orthopaedic Surgeons, Hip Society, Knee Society, and American Society of Regional Anesthesia and Pain Management.
    Methods: Databases including MEDLINE, EMBASE, and the Cochrane Central Registry of Controlled Trials were searched for studies published prior to November 2018 on NSAIDs in TJA. Studies included after a systematic review evaluated through direct comparisons and/or meta-analysis, including qualitative and quantitative heterogeneity testing, to evaluate effectiveness and safety of NSAIDs.
    Results: After critical appraisal of 2921 publications, 25 articles represented the best available evidence for inclusion in the analysis. Oral selective cyclooxygenase (COX)-2 and non-selective NSAIDs and intravenous ketorolac safely reduce postoperative pain and opioid consumption during the hospitalization for primary TJA. Administration of an oral selective COX-2 NSAID reduced postoperative opioid consumption after discharge from TKA.
    Conclusion: Strong evidence supports the use of an oral selective COX-2 or non-selective NSAID and intravenous ketorolac as adjunctive medications to manage postoperative pain during the hospitalization for TJA. Although no safety concerns were observed, prescribers need to remain vigilant when prescribing NSAIDs.
    MeSH term(s) Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Arthroplasty ; Humans ; Ketorolac/therapeutic use ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Pharmaceutical Preparations
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Pharmaceutical Preparations ; Ketorolac (YZI5105V0L)
    Language English
    Publishing date 2020-05-28
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2020.05.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Management of hip fractures in the elderly.

    Roberts, Karl C / Brox, W Timothy / Jevsevar, David S / Sevarino, Kaitlyn

    The Journal of the American Academy of Orthopaedic Surgeons

    2015  Volume 23, Issue 2, Page(s) 131–137

    Abstract: The purpose of this clinical practice guideline is to help improve treatment and management of hip fractures in the elderly based on current best evidence. The guideline contains twenty-five recommendations, including both diagnosis and treatment. Of ... ...

    Abstract The purpose of this clinical practice guideline is to help improve treatment and management of hip fractures in the elderly based on current best evidence. The guideline contains twenty-five recommendations, including both diagnosis and treatment. Of those recommendations, strong evidence supports regional analgesia to improve preoperative pain control, similar outcomes for general or spinal anesthesia, arthroplasty for patients with unstable (displaced) femoral neck fractures, the use of a cephalomedullary device for the treatment of patients with subtrochanteric or reverse obliquity fractures, a blood transfusion threshold of no higher than 8 g/dL in asymptomatic postoperative patients, intensive physical therapy postdischarge, use of an interdisciplinary care program in patients with mild to moderate dementia, and multimodal pain management after hip fracture surgery. In addition to the recommendations, the work group highlighted the need for better research in the treatment of hip fractures.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip ; Disease Management ; Fracture Fixation, Internal ; Hip Fractures/surgery ; Humans ; Risk Factors
    Language English
    Publishing date 2015-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-14-00432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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