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  1. Book ; Online: The Edinburgh companion to Sir Walter Scott

    Robertson, Fiona

    (Edinburgh companions to Scottish literature)

    2012  

    Abstract: This is a comprehensive collection devoted to the work of Sir Walter Scott, drawing on the innovative research and scholarship which have revitalised the study of the whole range of his exceptionally diverse writing in recent ... ...

    Institution ebrary, Inc
    Author's details edited by Fiona Robertson
    Series title Edinburgh companions to Scottish literature
    Abstract This is a comprehensive collection devoted to the work of Sir Walter Scott, drawing on the innovative research and scholarship which have revitalised the study of the whole range of his exceptionally diverse writing in recent years
    Language English
    Size Online-Ressource (xi, 195 p)
    Publisher Edinburgh University Press
    Publishing place Edinburgh
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 9780748641291 ; 9780748641307 ; 0748641297 ; 0748641300
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Genomic evidence of a functional RH2 opsin in New Zealand parrots and implications for pest control

    Grosser, Stefanie / Dutoit, Ludovic / Foster, Yasmin / Robertson, Fiona / Fidler, Andrew E. / Martini, Denise / Knapp, Michael / Robertson, Bruce C.

    New Zealand Journal of Zoology. 2023 Apr. 03, v. 50, no. 2 p.341-349

    2023  

    Abstract: Recent genomic evidence suggest that kea (Nestor notabilis) have a non-functional RH2 opsin gene potentially leading to impaired vision in the green region of the electromagnetic spectrum. In New Zealand, it is standard procedure to add green dye to ... ...

    Abstract Recent genomic evidence suggest that kea (Nestor notabilis) have a non-functional RH2 opsin gene potentially leading to impaired vision in the green region of the electromagnetic spectrum. In New Zealand, it is standard procedure to add green dye to aerial poison baits used in mammalian predator control operations to deter native birds from eating toxic bait. A visual deficiency could impact how kea perceive and interact with green-dyed baits and thus have unforeseen consequences for kea conservation. Here, we sequenced the partial RH2 gene of seven wild kea and re-analysed the kea genome raw sequencing data of the RH2 locus. We demonstrate that the reported premature stop codon is most likely an assembly artefact. An extended analysis of the published genomes of all three extant New Zealand parrots of the superfamily Strigopoidea confirms that the RH2 gene is functional in this entire group.
    Keywords Nestor notabilis ; dyes ; genomics ; loci ; mammals ; opsin ; predator control ; stop codon ; toxicity ; vision disorders ; zoology ; New Zealand ; Bird vision ; kea ; New Zealand parrots ; opsins ; pest control ; RH2
    Language English
    Dates of publication 2023-0403
    Size p. 341-349.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2098819-9
    ISSN 1175-8821 ; 0301-4223
    ISSN (online) 1175-8821
    ISSN 0301-4223
    DOI 10.1080/03014223.2022.2053554
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Evaluating Ultrasonicator Performance for Cyanobacteria Management at Freshwater Sources.

    Vaughan, Liam / Barnett, Dean / Bourke, Elisa / Burrows, Hamish / Robertson, Fiona / Smith, Brad / Cashmore, Jenna / Welk, Michael / Burch, Michael / Zamyadi, Arash

    Toxins

    2023  Volume 15, Issue 3

    Abstract: Algal blooms consisting of potentially toxic cyanobacteria are a growing source water management challenge faced by water utilities globally. Commercially available sonication devices are designed to mitigate this challenge by targeting cyanobacteria- ... ...

    Abstract Algal blooms consisting of potentially toxic cyanobacteria are a growing source water management challenge faced by water utilities globally. Commercially available sonication devices are designed to mitigate this challenge by targeting cyanobacteria-specific cellular features and aim to inhibit cyanobacterial growth within water bodies. There is limited available literature evaluating this technology; therefore, a sonication trial was conducted in a drinking water reservoir within regional Victoria, Australia across an 18-month period using one device. The trial reservoir, referred to as Reservoir C, is the final reservoir in a local network of reservoirs managed by a regional water utility. Sonicator efficacy was evaluated through qualitative and quantitative analysis of algal and cyanobacterial trends within Reservoir C and surrounding reservoirs using field data collected across three years preceding the trial and during the 18-month duration of the trial. Qualitative assessment revealed a slight increase in eukaryotic algal growth within Reservoir C following device installation, which is likely due to local environmental factors such as rainfall-driven nutrient influx. Post-sonication quantities of cyanobacteria remained relatively consistent, which may indicate that the device was able to counteract favorable phytoplankton growth conditions. Qualitative assessments also revealed minimal prevalence variations of the dominant cyanobacterial species within the reservoir following trial initiation. Since the dominant species were potential toxin producers, there is no strong evidence that sonication altered Reservoir C's water risk profiles during this trial. Statistical analysis of samples collected within the reservoir and from the intake pipe to the associated treatment plant supported qualitative observations and revealed a significant elevation in eukaryotic algal cell counts during bloom and non-bloom periods post-installation. Corresponding cyanobacteria biovolumes and cell counts revealed that no significant changes occurred, excluding a significant decrease in bloom season cell counts measured within the treatment plant intake pipe and a significant increase in non-bloom season biovolumes and cell counts as measured within the reservoir. One technical disruption occurred during the trial; however, this had no notable impacts on cyanobacterial prevalence. Acknowledging the limitations of the experimental conditions, data and observations from this trial indicate there is no strong evidence that sonication significantly reduced cyanobacteria occurrence within Reservoir C.
    MeSH term(s) Cyanobacteria ; Fresh Water/microbiology ; Phytoplankton ; Eutrophication ; Drinking Water
    Chemical Substances Drinking Water
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins15030186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Candidate gene polymorphisms are linked to dispersive and migratory behaviour: Searching for a mechanism behind the "paradox of the great speciators".

    Estandía, Andrea / Sendell-Price, Ashley T / Oatley, Graeme / Robertson, Fiona / Potvin, Dominique / Massaro, Melanie / Robertson, Bruce C / Clegg, Sonya M

    Journal of evolutionary biology

    2023  Volume 36, Issue 10, Page(s) 1503–1516

    Abstract: The "paradox of the great speciators" has puzzled evolutionary biologists for over half a century. A great speciator requires excellent dispersal propensity to explain its occurrence on multiple islands, but reduced dispersal ability to explain its high ... ...

    Abstract The "paradox of the great speciators" has puzzled evolutionary biologists for over half a century. A great speciator requires excellent dispersal propensity to explain its occurrence on multiple islands, but reduced dispersal ability to explain its high number of subspecies. A rapid reduction in dispersal ability is often invoked to solve this apparent paradox, but a proximate mechanism has not been identified yet. Here, we explored the role of six genes linked to migration and animal personality differences (CREB1, CLOCK, ADCYAP1, NPAS2, DRD4, and SERT) in 20 South Pacific populations of silvereye (Zosterops lateralis) that range from highly sedentary to partially migratory, to determine if genetic variation is associated with dispersal propensity and migration. We detected genetic associations in three of the six genes: (i) in a partial migrant population, migrant individuals had longer microsatellite alleles at the CLOCK gene compared to resident individuals from the same population; (ii) CREB1 displayed longer average microsatellite allele lengths in recently colonized island populations (<200 years), compared to evolutionarily older populations. Bayesian broken stick regression models supported a reduction in CREB1 length with time since colonization; and (iii) like CREB1, DRD4 showed differences in polymorphisms between recent and old colonizations but a larger sample is needed to confirm. ADCYAP1, SERT, and NPAS2 were variable but that variation was not associated with dispersal propensity. The association of genetic variants at three genes with migration and dispersal ability in silvereyes provides the impetus for further exploration of genetic mechanisms underlying dispersal shifts, and the prospect of resolving a long-running evolutionary paradox through a genetic lens.
    MeSH term(s) Animals ; Humans ; Animal Migration ; Bayes Theorem ; Polymorphism, Genetic ; Passeriformes/genetics ; Biological Evolution
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1465318-7
    ISSN 1420-9101 ; 1010-061X
    ISSN (online) 1420-9101
    ISSN 1010-061X
    DOI 10.1111/jeb.14222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Isolation and Deep Sequencing of Mitochondrial DNA.

    Bury, Alexander G / Robertson, Fiona M / Pyle, Angela / Payne, Brendan A I / Hudson, Gavin

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2277, Page(s) 433–447

    Abstract: In recent years, next-generation sequencing (NGS) has become a powerful tool for studying both inherited and somatic heteroplasmic mitochondrial DNA (mtDNA) variation. NGS has proved particularly powerful when combined with single-cell isolation ... ...

    Abstract In recent years, next-generation sequencing (NGS) has become a powerful tool for studying both inherited and somatic heteroplasmic mitochondrial DNA (mtDNA) variation. NGS has proved particularly powerful when combined with single-cell isolation techniques, allowing the investigation of low-level heteroplasmic variants both between cells and within tissues. Nevertheless, there remain significant challenges, especially around the selective enrichment of mtDNA from total cellular DNA and the avoidance of nuclear pseudogenes. This chapter summarizes the techniques needed to enrich, amplify, sequence, and analyse mtDNA using NGS .
    Language English
    Publishing date 2021-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1270-5_27
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: The Edinburgh companion to Sir Walter Scott

    Robertson, Fiona / Scott, Walter

    (Edinburgh companions to Scottish literature)

    2012  

    Abstract: This is a comprehensive collection devoted to the work of Sir Walter Scott, drawing on the innovative research and scholarship which have revitalised the study of the whole range of his exceptionally diverse writing in recent ... ...

    Title variant Sir Walter Scott
    Author's details ed. by Fiona Robertson
    Series title Edinburgh companions to Scottish literature
    Abstract This is a comprehensive collection devoted to the work of Sir Walter Scott, drawing on the innovative research and scholarship which have revitalised the study of the whole range of his exceptionally diverse writing in recent years
    Language English
    Size XI, 195 S.
    Publisher Edinburgh Univ. Press
    Publishing place Edinburgh
    Document type Book
    Note Literaturverz. S. 181 - 184
    ISBN 0748641297 ; 0748641300 ; 9780748641291 ; 9780748641307 ; 9780748670192 ; 9780748670208 ; 9780748670215 ; 074867019X ; 0748670203 ; 0748670211
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article ; Online: Mitochondrial DNA Damage and Brain Aging in Human Immunodeficiency Virus.

    Roca-Bayerri, Carla / Robertson, Fiona / Pyle, Angela / Hudson, Gavin / Payne, Brendan A I

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 73, Issue 2, Page(s) e466–e473

    Abstract: Background: Neurocognitive impairment (NCI) remains common in people living with human immunodeficiency virus (PLWH), despite suppressive antiretroviral therapy (ART), but the reasons remain incompletely understood. Mitochondrial dysfunction is a ... ...

    Abstract Background: Neurocognitive impairment (NCI) remains common in people living with human immunodeficiency virus (PLWH), despite suppressive antiretroviral therapy (ART), but the reasons remain incompletely understood. Mitochondrial dysfunction is a hallmark of aging and of neurodegenerative diseases. We hypothesized that human immunodeficiency virus (HIV) or ART may lead to mitochondrial abnormalities in the brain, thus contributing to NCI.
    Methods: We studied postmortem frozen brain samples from 52 PLWH and 40 HIV-negative controls. Cellular mitochondrial DNA (mtDNA) content and levels of large-scale mtDNA deletions were measured by real-time polymerase chain reaction. Heteroplasmic mtDNA point mutations were quantified by deep sequencing (Illumina). Neurocognitive data were taken within 48 months antemortem.
    Results: We observed a decrease in mtDNA content, an increase in the mtDNA "common deletion," and an increase in mtDNA point mutations with age (all P < .05). Each of these changes was exacerbated in HIV-positive cases compared with HIV-negative controls (all P < .05). ART exposures, including nucleoside analogue reverse transcriptase inhibitors, were not associated with changes in mtDNA. The number of mtDNA point mutations was associated with low CD4/CD8 ratio (P = .04) and with NCI (global T-score, P = .007).
    Conclusions: In people with predominantly advanced HIV infection, there is exacerbation of age-associated mtDNA damage. This change is driven by HIV per se rather than by ART toxicity and may contribute to NCI. These data suggest that mitochondrial dysfunction may be a mediator of adverse aging phenotypes in PLWH.
    MeSH term(s) Aging/genetics ; Brain ; DNA, Mitochondrial/genetics ; HIV ; HIV Infections/complications ; Humans ; Mitochondria/genetics
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2020-07-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Feasibility and impact of haplogroup matching for mitochondrial replacement treatment.

    Takeda, Yuko / Hyslop, Louise / Choudhary, Meenakshi / Robertson, Fiona / Pyle, Angela / Wilson, Ian / Santibanez-Koref, Mauro / Turnbull, Douglass / Herbert, Mary / Hudson, Gavin

    EMBO reports

    2023  Volume 24, Issue 10, Page(s) e54540

    Abstract: Mitochondrial replacement technology (MRT) aims to reduce the risk of serious disease in children born to women who carry pathogenic mitochondrial DNA (mtDNA) variants. By transplanting nuclear genomes from eggs of an affected woman to enucleated eggs ... ...

    Abstract Mitochondrial replacement technology (MRT) aims to reduce the risk of serious disease in children born to women who carry pathogenic mitochondrial DNA (mtDNA) variants. By transplanting nuclear genomes from eggs of an affected woman to enucleated eggs from an unaffected donor, MRT creates new combinations of nuclear and mtDNA. Based on sets of shared sequence variants, mtDNA is classified into ~30 haplogroups. Haplogroup matching between egg donors and women undergoing MRT has been proposed as a means of reducing mtDNA sequence divergence between them. Here we investigate the potential effect of mtDNA haplogroup matching on clinical delivery of MRT and on mtDNA sequence divergence between donor/recipient pairs. Our findings indicate that haplogroup matching would limit the availability of egg donors such that women belonging to rare haplogroups may have to wait > 4 years for treatment. Moreover, we find that intra-haplogroup sequence variation is frequently within the range observed between randomly matched mtDNA pairs. We conclude that haplogroup matching would restrict the availability of MRT, without necessarily reducing mtDNA sequence divergence between donor/recipient pairs.
    MeSH term(s) Child ; Humans ; Female ; Feasibility Studies ; Haplotypes ; Mitochondria/genetics ; DNA, Mitochondrial/genetics
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2023-08-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020896-0
    ISSN 1469-3178 ; 1469-221X
    ISSN (online) 1469-3178
    ISSN 1469-221X
    DOI 10.15252/embr.202154540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Decolonisation initiatives at the Institute of Tropical Medicine, Antwerp, Belgium: ready for change?

    Affun-Adegbulu, Clara / Cosaert, Theo / Meudec, Marie / Michielsen, Joris / Van de Pas, Remco / Van Belle, Sara / Put, Willem Van De / Soors, Werner / Robertson, Fiona / Ddungu, Charles

    BMJ global health

    2023  Volume 8, Issue 5

    Abstract: In a global context, the pernicious effects of colonialism and coloniality are increasingly being recognised in many sectors. As a result, calls to reverse colonial aphasia and amnesia, and decolonise, are getting stronger. This raises a number of ... ...

    Abstract In a global context, the pernicious effects of colonialism and coloniality are increasingly being recognised in many sectors. As a result, calls to reverse colonial aphasia and amnesia, and decolonise, are getting stronger. This raises a number of questions, particularly for entities that acted as agents of (previous) colonising countries and worked to further the progress of the colonial project: What does decolonisation mean for such historically colonial entities? How can they confront their (forgotten) arsonist past while addressing their current role in maintaining coloniality, at home and abroad? Given the embeddedness of many such entities in current global (power) structures of coloniality, do these entities really want change, and if so, how can such entities redefine their future to ensure that they are and remain 'decolonised'? We attempt to answer these questions, by reflecting on our efforts to think through and start the process of decolonisation at the Institute of Tropical Medicine (ITM) in Antwerp, Belgium. The overarching aim is to contribute to closing the gap in the literature when it comes to documenting practical efforts at decolonisation, particularly in contexts similar to ITM and to share our experience and engage with others who are undertaking or planning to undertake similar initiatives.
    MeSH term(s) Humans ; Belgium ; Tropical Medicine ; Colonialism
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Journal Article
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2023-011748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Mayo's Hawthorne study

    Robertson, Fiona

    Gower handbook of internal communication , p. 153-155

    2009  , Page(s) 153–155

    Author's details by Fiona Robertson
    Keywords Arbeitsverhalten
    Language English
    Publisher Gower
    Publishing place Farnham [u.a.]
    Document type Article
    ISBN 978-0-566-08689-2 ; 0-566-08689-1
    Database ECONomics Information System

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