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  1. Book ; Online ; E-Book: Plasma cell dyscrasias

    Roccaro, Aldo M. / Ghobrial, Irene M.

    (Cancer treatment and research)

    2017  

    Author's details Aldo M. Roccaro, Irene M. Ghobrial editors
    Series title Cancer treatment and research
    Keywords Bone marrow microenvironment ; Genetics ; Multiple Myeloma ; Plasma cell dyscrasias ; Therapies
    Language English
    Size 1 Online-Ressource (vi, 361 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019381187
    ISBN 978-3-319-40320-5 ; 9783319403182 ; 3-319-40320-6 ; 3319403184
    DOI 10.1007/978-3-319-40320-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Waking up exhausted BCMA-specific T cells in myeloma.

    Sacco, Antonio / Roccaro, Aldo M

    Blood

    2024  Volume 143, Issue 10, Page(s) 840–841

    MeSH term(s) Humans ; Multiple Myeloma ; B-Cell Maturation Antigen ; Induced Pluripotent Stem Cells ; T-Lymphocytes ; CD8 Antigens
    Chemical Substances B-Cell Maturation Antigen ; CD8alphabeta antigen ; CD8 Antigens
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023023037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Starving multiple myeloma cells via CDK7 inhibition.

    Sacco, Antonio / Roccaro, Aldo M

    Blood

    2023  Volume 141, Issue 23, Page(s) 2787–2788

    MeSH term(s) Humans ; Multiple Myeloma/drug therapy ; Cyclin-Dependent Kinases ; Cyclin-Dependent Kinase-Activating Kinase
    Chemical Substances Cyclin-Dependent Kinases (EC 2.7.11.22) ; Cyclin-Dependent Kinase-Activating Kinase (EC 2.7.11.22)
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023020254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: The Bone Marrow Niche in Normal and Malignant Haematopoiesis.

    Colombo, Michela / Norfo, Ruggiero / Bianchi, Giada / Roccaro, Aldo M

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 870114

    Language English
    Publishing date 2022-02-28
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.870114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editor's Note: Mechanisms of Activity of the TORC1 Inhibitor Everolimus in Waldenstrom Macroglobulinemia.

    Roccaro, Aldo M / Sacco, Antonio / Jia, Xiaojing / Banwait, Ranjit / Maiso, Patricia / Azab, Feda / Flores, Ludmila / Manier, Salomon / Kareem Azab, Abdel / Ghobrial, Irene M

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2024  Volume 30, Issue 4, Page(s) 919

    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-24-0178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Editor's Note: Eph-B2/Ephrin-B2 Interaction Plays a Major Role in the Adhesion and Proliferation of Waldenstrom's Macroglobulinemia.

    Azab, Feda / Azab, Abdel Kareem / Maiso, Patricia / Calimeri, Teresa / Flores, Ludmila / Liu, Yang / Quang, Phong / Roccaro, Aldo M / Sacco, Antonio / Ngo, Hai T / Zhang, Yong / Morgan, Brittany L / Carrasco, Ruben D / Ghobrial, Irene M

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2024  Volume 30, Issue 4, Page(s) 920

    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-24-0180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Epigenetic Aberrations in Multiple Myeloma.

    Caprio, Cinzia / Sacco, Antonio / Giustini, Viviana / Roccaro, Aldo M

    Cancers

    2020  Volume 12, Issue 10

    Abstract: Multiple myeloma (MM) is a plasma cell dyscrasia characterized by proliferation of clonal plasma cells within the bone marrow. Several advances in defining key processes responsible for MM pathogenesis and disease progression have been made; and ... ...

    Abstract Multiple myeloma (MM) is a plasma cell dyscrasia characterized by proliferation of clonal plasma cells within the bone marrow. Several advances in defining key processes responsible for MM pathogenesis and disease progression have been made; and dysregulation of epigenetics, including DNA methylation and histone modification, has emerged as a crucial regulator of MM pathogenesis. In the present review article, we will focus on the role of epigenetic modifications within the specific context of MM.
    Language English
    Publishing date 2020-10-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers12102996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Plasma cell dyscrasias

    Roccaro, Aldo M / Ghobrial, Irene M

    (Cancer treatment and research, ; volume 169)

    2016  

    Author's details Aldo M. Roccaro, Irene M. Ghobrial, editors
    Series title Cancer treatment and research, ; volume 169
    MeSH term(s) Paraproteinemias
    Language English
    Size v, 361 pages :, illustrations.
    Document type Book
    ISBN 9783319403182 ; 9783319403205 ; 3319403184 ; 3319403206
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article: Liquid Biopsy in Cancer: Focus on Lymphoproliferative Disorders.

    Savino, Francesco D / Rigali, Fabio / Giustini, Viviana / D'Aliberti, Deborah / Spinelli, Silvia / Piazza, Rocco / Sacco, Antonio / Roccaro, Aldo M

    Cancers

    2022  Volume 14, Issue 21

    Abstract: Within the context of precision medicine, the scientific community is giving particular attention to early diagnosis and intervention, guided by non-invasive methodologies. Liquid biopsy (LBx) is a recent laboratory approach consisting of a non-invasive ... ...

    Abstract Within the context of precision medicine, the scientific community is giving particular attention to early diagnosis and intervention, guided by non-invasive methodologies. Liquid biopsy (LBx) is a recent laboratory approach consisting of a non-invasive blood draw, which allows the detection of information about potential prognostic factors, or markers to be used for diagnostic purposes; it might also allow the clinician to establish a treatment regimen and predict a patient's response. Since the discovery of circulating tumor cells (CTCs) in the nineteenth century, the possibility of integrating LBx into clinical practice has been explored, primarily because of its safeness and easy execution: indeed, compared to solid biopsy, sampling-related risks are less of a concern, and the quickness and repeatability of the process could help confirm a prompt diagnosis or to further corroborate the existence of a metastatic spreading of the disease. LBx's usefulness has been consolidated in a narrow range of oncological settings, first of all, non-small cell lung carcinoma (NSCLC), and it is now gradually being assessed also in lymphoproliferative diseases, such as acute lymphocytic leukemia (ALL), B-cell lymphomas, and multiple myeloma. The present review aims to summarize LBx's overall characteristics (such as its advantages and flaws, collection and analysis methodologies, indications, and targets of the test), and to highlight the applications of this technique within the specific field of B-cell malignancies. The perspectives on how such a simple and convenient technique could improve hemato-oncological clinical practice are broadly encouraging, yet far from a complete integration in routine clinical settings.
    Language English
    Publishing date 2022-10-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14215378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: microRNA aberrations and their role in supporting hematologic malignancies.

    Roccaro, Aldo M / Ghobrial, Irene M

    MicroRNA (Shariqah, United Arab Emirates)

    2014  Volume 2, Issue 3, Page(s) 157

    Language English
    Publishing date 2014-07-25
    Publishing country United Arab Emirates
    Document type Editorial
    ISSN 2211-5374
    ISSN (online) 2211-5374
    DOI 10.2174/221153660203140121105709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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