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  1. Article: The Evolution of Educational Events during the COVID-19 Pandemic: The Experience of G.Re.T.A. Foundation.

    Rocco, Nicola / Catanuto, Giuseppe / Masannat, Yazan / Nava, Maurizio Bruno

    Breast care (Basel, Switzerland)

    2023  Volume 18, Issue 3, Page(s) 200–202

    Abstract: Introduction: The educational and professional lives of everyone have significantly been affected by the COVID-19 pandemic. Many courses and meetings traditionally structured and organized as face-to-face events have been transformed into virtual events. ...

    Abstract Introduction: The educational and professional lives of everyone have significantly been affected by the COVID-19 pandemic. Many courses and meetings traditionally structured and organized as face-to-face events have been transformed into virtual events.
    Methods: We report on the experience of G.Re.T.A. Fondazione in organizing international conferences, webinars, and masterclasses on oncoplastic and aesthetic breast surgery before, during, and after the pandemic.
    Results: The organization of the meetings as online or hybrid events allowed to maintain a high number of participants with numbers being in line with those achieved in the traditional face-to-face events or even showing an increased number of participants, in particular from countries not traditionally involved such as Saudi Arabia, the United Arab Emirates, India, and Russian Federation.
    Discussion: We think that the hybrid modality is likely to become a gold standard, even though purely online meetings will still survive in the post-pandemic era. Webinars are frugal and highly efficient events that can easily reach a worldwide audience with acceptable interaction.
    Language English
    Publishing date 2023-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2202236-3
    ISSN 1661-3805 ; 1661-3791
    ISSN (online) 1661-3805
    ISSN 1661-3791
    DOI 10.1159/000530033
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  2. Article ; Online: An Unusual Case of BIA-ALCL Associated with Prolonged/Complicated Biocell-Textured Expander, followed by Smooth Round Breast Implant Exposure, and Concurrent Use of Adalimumab.

    Rocco, Nicola / Catanuto, Giuseppe / Nava, Maurizio Bruno

    Plastic and reconstructive surgery

    2022  Volume 150, Issue 4, Page(s) 913e–914e

    MeSH term(s) Adalimumab/adverse effects ; Breast Implantation/adverse effects ; Breast Implants/adverse effects ; Breast Neoplasms/complications ; Female ; Humans ; Lymphoma, Large-Cell, Anaplastic/etiology ; Tissue Expansion Devices/adverse effects
    Chemical Substances Adalimumab (FYS6T7F842)
    Language English
    Publishing date 2022-08-11
    Publishing country United States
    Document type Case Reports ; Letter ; Comment
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000009501
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  3. Article ; Online: More evidence for implant-based breast reconstruction.

    Rocco, Nicola / Catanuto, Giuseppe

    The Lancet. Oncology

    2019  Volume 20, Issue 2, Page(s) 174–175

    MeSH term(s) Breast Implants ; Breast Neoplasms/surgery ; Humans ; Mammaplasty ; Mastectomy ; Prospective Studies ; Surgical Mesh
    Language English
    Publishing date 2019-01-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(18)30831-3
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  4. Article ; Online: Perioperative nursing care speed up recover of a male patient after bilateral endoscopic mastectomy: a case report.

    Wang, Li-Ping / Salzberg, C Andrew / Benson, John R / Rocco, Nicola / Liang, Shan-Shan

    AME case reports

    2023  Volume 7, Page(s) 48

    Abstract: Background: Gynecomastia (GYN) is mainly caused by the benign proliferation of mammary glands and adipose tissue. Currently, up to 38% of adult males have GYN. GYN can be caused by systemic diseases, obesity, endocrine disorders (such as liver cirrhosis, ...

    Abstract Background: Gynecomastia (GYN) is mainly caused by the benign proliferation of mammary glands and adipose tissue. Currently, up to 38% of adult males have GYN. GYN can be caused by systemic diseases, obesity, endocrine disorders (such as liver cirrhosis, which impairs estrogen inactivation), malignant tumors, and medications. Surgical intervention is required after 12 months pharmacological treatment of GYN was no response who have endocrine disorder, or due to psychological and physiological factors, young patients have a higher demand for surgical intervention. Recent advances in minimally invasive endoscopic surgery, with the advantage of rapid rehabilitation, have markedly improved the surgical management of GYN.
    Case description: In November 2021, we admitted a young patient with bilateral GYN whose problem began several years prior and for which he sought surgical intervention. After comprehensive evaluation and psychological consultation, he underwent surgical treatment. The present case report summarizes our experience in nursing this patient.
    Conclusions: Perioperative nursing care is essential in the management of patients undergoing endoscopic surgical treatment for GYN. The nursing team must be knowledgeable about the procedure, assess and manage the patient's pain, monitor vital signs, prevent infections, and provide emotional support to the patient. With proper nursing care, patients can recover smoothly and quickly after endoscopic surgical treatment of GYN.
    Language English
    Publishing date 2023-09-18
    Publishing country China
    Document type Case Reports
    ISSN 2523-1995
    ISSN (online) 2523-1995
    DOI 10.21037/acr-23-101
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  5. Article ; Online: Breast-Conserving Surgery or Mastectomy?: Impact on Survival.

    Christiansen, Peer / Mele, Marco / Bodilsen, Anne / Rocco, Nicola / Zachariae, Robert

    Annals of surgery open : perspectives of surgical history, education, and clinical approaches

    2022  Volume 3, Issue 4, Page(s) e205

    Abstract: The early randomized controlled trials revealed no differences in survival between breast-conserving surgery (BCS) and mastectomy. However, breast cancer treatment has undergone changes, and the results of recent population-based registry studies suggest ...

    Abstract The early randomized controlled trials revealed no differences in survival between breast-conserving surgery (BCS) and mastectomy. However, breast cancer treatment has undergone changes, and the results of recent population-based registry studies suggest superior long-term survival after BCS. To explore the current evidence, a systematic review and meta-ana lysis of population-based observational studies from 2010 and onward was conducted.
    Methods: A literature search was conducted in the PubMed, Embase, and Cochrane databases to identify relevant literature. Keywords included "mastectomy," "breast conserving surgery," and "survival." The identified studies were narratively reviewed and effect sizes (hazard ratios [HRs]) for overall (OS) and breast cancer-specific survival (BCSS) were combined with random-effects models.
    Results: A total of 30 reports were included in the review, and results from 25 studies were included in the meta-analyses. Compared with mastectomy, BCS was associated with better OS (HR = 1.34 [1.20-1.51]; N = 1,311,600) and BCSS (HR = 1.38 [1.29-1.47]; N = 494,267). Selected subgroups of patients, based on lymph node status, age (<50 years/≥50 years), and radiation therapy after mastectomy (±), all showed better overall survival after BCS. The number (range 4-12) and type of prognostic variables adjusted for in the survival analyses of the studies did not statistically significantly moderate the differences in survival between BCS and mastectomy.
    Conclusions: The combined findings from large population-based studies indicate that BCS is associated with survival benefit compared with mastectomy, suggesting that BCS be the recommended treatment of early breast cancer (T1-2N0-1M0) if a radical lumpectomy can be performed.
    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3593
    ISSN (online) 2691-3593
    DOI 10.1097/AS9.0000000000000205
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  6. Article ; Online: Nanotextured Breast Implants: Not a Solution for All Seasons.

    Nava, Maurizio Bruno / Catanuto, Giuseppe / Rocco, Nicola

    Aesthetic surgery journal

    2021  Volume 41, Issue 4, Page(s) NP137–NP138

    MeSH term(s) Breast Implantation/adverse effects ; Breast Implants/adverse effects ; Humans ; Mammaplasty
    Language English
    Publishing date 2021-01-30
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjaa273
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    Zs.A 5721: Show issues Location:
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    Zs.MO 570: Show issues

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  7. Article ; Online: Is Breast Implant Associated-Anaplastic Large Cell Lymphoma linked to textured implants?

    Nava, Maurizio Bruno / Chiodini, Paolo / Catanuto, Giuseppe / Rocco, Nicola

    Aesthetic plastic surgery

    2021  Volume 45, Issue 6, Page(s) 2593–2601

    Abstract: Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL) is a distinctive type of T-cell lymphoma arising around breast implants. We performed a review of the existing literature with the aim of providing an evidence-based overview of the ... ...

    Abstract Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL) is a distinctive type of T-cell lymphoma arising around breast implants. We performed a review of the existing literature with the aim of providing an evidence-based overview of the available data on BIA-ALCL with a standardized evaluation of the quality of the studies and investigating the potential association between textured breast implants and BIA-ALCL.We analyzed the literature reporting estimates of relative or absolute risks of BIA-ALCL in case-control, cohort studies and case series studies. The total number of BIA-ALCL cases reported in literature is very low. Furthermore, most of the reported cases have been reported in case-control studies or case series. This means that our knowledge is based on a low level of evidence. Moreover, low-medium quality scores were observed in the included case series studies. In relation to the rarity of the event, better information could only derived by international cooperation to pool together data deriving from all over the world, with the clear need of better reporting patients and implant characteristics in case series and when adding data to public registries. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Breast Implantation/adverse effects ; Breast Implants/adverse effects ; Breast Neoplasms/epidemiology ; Breast Neoplasms/etiology ; Case-Control Studies ; Female ; Humans ; Lymphoma, Large-Cell, Anaplastic/epidemiology ; Lymphoma, Large-Cell, Anaplastic/etiology ; Lymphoma, Large-Cell, Anaplastic/surgery
    Language English
    Publishing date 2021-04-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-021-02260-0
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  8. Article ; Online: Three Pedicles-Based Nipple-Sparing Skin-Reducing Mastectomy (TP-NSSRM) combined with Pre-Pectoral Implant-Based Breast Reconstruction.

    La Padula, Simone / Pensato, Rosita / Al-Amer, Rasmieh / Hersant, Barbara / Meningaud, Jean Paul / Noel, Warren / D'Andrea, Francesco / Rocco, Nicola

    Plastic and reconstructive surgery

    2023  

    Abstract: Introduction: Nipple-sparing mastectomy (NSM) and immediate breast reconstruction have demonstrated positive aesthetic outcomes and high patient satisfaction. However, challenges arise when performing NSM on patients with large and ptotic breasts due to ...

    Abstract Introduction: Nipple-sparing mastectomy (NSM) and immediate breast reconstruction have demonstrated positive aesthetic outcomes and high patient satisfaction. However, challenges arise when performing NSM on patients with large and ptotic breasts due to the higher risk of nipple-areolar complex (NAC) necrosis. This study proposes a new technique: the three pedicles-based nipple-sparing skin-reducing mastectomy (TP-NSSRM), combined with direct-to-implant (DTI) breast reconstruction, aimed at reducing complications.
    Materials and methods: A prospective study was conducted from November 2021 to April 2022, enrolling patients with large and drooping breasts requiring mastectomy for breast cancer treatment or risk reduction. Patient selection criteria included a sternal notch to nipple distance of ≥ 23 cm, Grade 3 ptosis, and eligibility for immediate prepectoral DTI breast reconstruction. Patient satisfaction was assessed using BREAST-Q modules.
    Results: Seventy-two TP-NSSRM procedures combined with immediate DTI-based breast reconstruction were performed on a total of 45 patients. High patient satisfaction was observed, and statistically significant improvements were noted in postoperative BREAST-Q scores (p=0.001). The complication rate was low, and preservation of the nipple-areolar complex was achieved in all cases.
    Conclusion: The TP-NSSRM technique offers a potential solution for patients with large and drooping breasts undergoing NSM. It aims to minimize complications and achieve satisfactory outcomes. This study demonstrates favorable results in terms of patient satisfaction and quality of life. Further research and long-term follow-up are necessary to validate these findings and evaluate the long-term outcomes of this technique.
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000011092
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  9. Article ; Online: Chest wall perforator flaps for breast reconstruction: international survey on attitudes and training needs.

    Karakatsanis, Andreas / Sund, Malin / Rocco, Nicola / Dietz, Jill R / Kothari, Ashutosh / Hamdi, Mustapha / Masannat, Yazan A / Barry, Peter A

    The British journal of surgery

    2023  Volume 110, Issue 8, Page(s) 966–972

    Abstract: Background: Volume replacement using chest wall perforator flaps (CWPFs) is a promising technique to reduce mastectomy rates without sacrificing function or aesthetics. Owing to limited availability of the technique, only a minority of patients ... ...

    Abstract Background: Volume replacement using chest wall perforator flaps (CWPFs) is a promising technique to reduce mastectomy rates without sacrificing function or aesthetics. Owing to limited availability of the technique, only a minority of patients currently have access to CWPF procedures.
    Methods: An international web-based survey was disseminated through social media, dedicated webpages, and national and international societies for breast surgery. The survey explored surgeons' attitudes towards CWPFs and their perceived training needs.
    Results: Of 619 respondents, 88.4 per cent agreed that CWPF surgery was desirable, with one-third offering it and performing a median of 10 (i.q.r. 5-15) procedures annually. They were more likely to be senior (OR 1.35, 95 per cent c.i. 1.18 to 1.55; P < 0.001), with formal oncoplastic training (OR 4.80, 3.09 to 7.48; P < 0.001), and working in larger units (OR 1.18, 1.03 to 1.35; P = 0.018) with a free-flap (OR 1.62, 1.06 to 2.48; P = 0.025) or CWPF (OR 3.02, 1.87 to 4.89; P < 0.001) service available. In cluster and latent class analysis, none showed high cohesion with performance of CWPF surgery.
    Conclusion: There is a discrepancy between perceived importance and availability of CWPF surgery, indicating that optimal training is needed.
    MeSH term(s) Humans ; Female ; Mastectomy ; Perforator Flap ; Thoracic Wall/surgery ; Breast Neoplasms/surgery ; Mammaplasty/methods ; Surveys and Questionnaires ; Attitude
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znad145
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  10. Article ; Online: New techniques versus standard mapping for sentinel lymph node biopsy in breast cancer: a systematic review and meta-analysis.

    Rocco, Nicola / Velotti, Nunzio / Pontillo, Martina / Vitiello, Antonio / Berardi, Giovanna / Accurso, Antonello / Masone, Stefania / Musella, Mario

    Updates in surgery

    2023  Volume 75, Issue 6, Page(s) 1699–1710

    Abstract: New tracers for sentinel lymph node biopsy (SLNB), as indocyanine green (ICG), superparamagnetic iron oxide (SPIO) and micro bubbles, have been recently introduced in clinical practice showing promising but variable results. We reviewed the available ... ...

    Abstract New tracers for sentinel lymph node biopsy (SLNB), as indocyanine green (ICG), superparamagnetic iron oxide (SPIO) and micro bubbles, have been recently introduced in clinical practice showing promising but variable results. We reviewed the available evidence comparing these new techniques with the standard tracers to evaluate their safety. To identify all available studies, a systematic search was performed in all electronic databases. Data regarding sample size, mean number of SLN harvested for patient, number of metastatic SLN and SLN identification rate of all studies were extracted. No significant differences were found in terms of SLNs identification rates between SPIO, RI and BD but with a higher identification rate with the use of ICG. No significant differences were also found for the number of metastatic lymph nodes identified between SPIO, RI and BD and the mean number of SLNs identified between SPIO and ICG versus conventional tracers. A statistically significant differences in favor of ICG was reported for the comparison between ICG and conventional tracers for the number of metastatic lymph nodes identified. Our meta-analysis demonstrates that the use of both ICG and SPIO for the pre-operative mapping of sentinel lymph nodes in breast cancer treatment is adequately effective.
    MeSH term(s) Humans ; Female ; Sentinel Lymph Node Biopsy/methods ; Breast Neoplasms/surgery ; Breast Neoplasms/pathology ; Coloring Agents ; Sentinel Lymph Node/surgery ; Sentinel Lymph Node/pathology ; Indocyanine Green ; Lymph Nodes/pathology
    Chemical Substances Coloring Agents ; ferric oxide (1K09F3G675) ; Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2023-06-16
    Publishing country Italy
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01560-1
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