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  1. Book: Rapport de la mission ERS 2008

    Roche, Nicolas

    Berlin, 4 - 8 octobre 2008

    (Revue de maladies respiratoires : Actualités ; 1,1)

    2009  

    Title variant Mission ERS emergence
    Institution European Respiratory Society
    Author's details nr. coordonné par Nicolas Roche
    Series title Revue de maladies respiratoires : Actualités ; 1,1
    Revue des maladies respiratoires
    Revue de maladies respiratoires ; Actualités
    Collection Revue des maladies respiratoires
    Revue de maladies respiratoires ; Actualités
    Language French
    Size 72 S. : Ill., graph. Darst.
    Publisher Elsevier Masson
    Publishing place Issy-les-Moulineaux
    Publishing country France
    Document type Book
    Accompanying material CD-ROM: Mission ERS emergence
    HBZ-ID HT015917451
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Conference proceedings: Aspects actuels de l'évolution clinique de la BPCO

    Roche, Nicolas

    Berlin, 5 octobre 2008 [symposium]

    (Revue des maladies respiratoires ; 25,Déc., Beil. : Actualités)

    2008  

    Author's details numéro coordonné par Nicolas Roche
    Series title Revue des maladies respiratoires ; 25,Déc., Beil. : Actualités
    Collection
    Language French
    Size 24 S. : graph. Darst.
    Publisher Elsevier-Masson
    Publishing place S.l.
    Publishing country France
    Document type Book ; Conference proceedings
    HBZ-ID HT015814343
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Conference proceedings: Mission Clinical Conference on COPD

    Roche, Nicolas

    Londres, 2 - 3 mars 2007

    (Revue des maladies respiratoires ; 24, Nov.)

    2007  

    Event/congress Clinical Conference on COPD (2007, London)
    Author's details coordinateur: Nicolas Roche
    Series title Revue des maladies respiratoires ; 24, Nov.
    Collection
    Language French
    Size 51 S. : graph. Darst.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book ; Conference proceedings
    HBZ-ID HT015378322
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Rapport de la mission ERS 2006

    Roche, Nicolas

    Munich, 2 - 6 septembre 2006

    (Revue des maladies respiratoires ; 24,Jan., Beil. : Actualités)

    2007  

    Title variant Mission ERS 2006
    Institution European Respiratory Society
    Author's details coord. par Nicolas Roche
    Series title Revue des maladies respiratoires ; 24,Jan., Beil. : Actualités
    Collection
    Language French
    Size 80 S. : Ill.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book
    HBZ-ID HT015029764
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Rapport de la mission ERS 2005

    Roche, Nicolas

    Copenhague, 17 - 21 septembre 2005

    (Revue des maladies respiratoires ; 23,1, Cah. 2 : Actualités)

    2006  

    Institution European Respiratory Society
    Author's details coord. par Nicolas Roche
    Series title Revue des maladies respiratoires ; 23,1, Cah. 2 : Actualités
    Collection
    Language French
    Size 2S59 S. : graph. Darst.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book
    HBZ-ID HT014735736
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Diagnostic et évaluation de la gravité de la BPCO.

    Regard, Lucile / Roche, Nicolas

    La Revue du praticien

    2024  Volume 74, Issue 3, Page(s) 318–322

    Abstract: COPD: DIAGNOSTIC AND SEVERITY ASSESSMENT. Chronic obstructive pulmonary disease (COPD) is a frequent and underdiagnosed respiratory disease and a leading cause of morbidity and mortality. It should be suspected in patients aged 40 and over presenting ... ...

    Title translation COPD: diagnostic and severity assessment.
    Abstract COPD: DIAGNOSTIC AND SEVERITY ASSESSMENT. Chronic obstructive pulmonary disease (COPD) is a frequent and underdiagnosed respiratory disease and a leading cause of morbidity and mortality. It should be suspected in patients aged 40 and over presenting with persistent respiratory symptoms (cough, sputum, shortness of breath, recurrent respiratory tract infections) and a history of exposure to risk factors for the disease (smoking, occupational or domestic exposure to noxious particles). Spirometry is required to confirm the diagnosis of COPD, showing persistent airflow limitation with a post-bronchodilator FEV1/FCV inférieur 0.7. COPD assessment includes: classification of airflow limitation severity with post-bronchodilator FEV1 measurement (GOLD score from 1 to 4), clinical severity assessment (intensity of dyspnea, number and severity of acute exacerbations, impaired quality of life) and evaluation of associated complications (chronic respiratory failure, hypercapnia, pulmonary hypertension). Comorbidities are frequent and should be carefully sought: lung cancer, cardiovascular diseases, metabolic syndrome, skeletal muscle dysfunction, sleep apnea syndrome, osteoporosis, anxiety and depression.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Quality of Life ; Bronchodilator Agents ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Lung ; Comorbidity ; Dyspnea ; Severity of Illness Index
    Chemical Substances Bronchodilator Agents
    Language French
    Publishing date 2024-03-29
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Evolving Contours of COPD.

    Roche, Nicolas / Han, MeiLan K

    American journal of respiratory and critical care medicine

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202403-0565ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Systemic Medications in Chronic Obstructive Pulmonary Disease: Use and Outcomes.

    Roche, Nicolas

    Thoracic surgery clinics

    2021  Volume 31, Issue 2, Page(s) 97–106

    Abstract: Inhaled therapy remains the cornerstone of chronic obstructive pulmonary disease pharmacologic care, but some systemic treatments can be of help when the burden of the disease remains high. Azithromycin, phosphodiesterase-4 inhibitors, and mucoactive ... ...

    Abstract Inhaled therapy remains the cornerstone of chronic obstructive pulmonary disease pharmacologic care, but some systemic treatments can be of help when the burden of the disease remains high. Azithromycin, phosphodiesterase-4 inhibitors, and mucoactive agents can be used in such situations. The major difficulty remains in the identification of the optimal target populations. Another difficulty is to determine how these treatments should be positioned in the global treatment algorithm. For instance, should they be prescribed in addition to other antiinflammatory agents or should they replace them in some cases? Research is ongoing to identify new therapeutic targets.
    MeSH term(s) Administration, Oral ; Adrenal Cortex Hormones/therapeutic use ; Animals ; Azithromycin/therapeutic use ; Humans ; Macrolides/therapeutic use ; Morphine/therapeutic use ; Oxidative Stress ; Phosphodiesterase Inhibitors/therapeutic use ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Theophylline/therapeutic use ; Treatment Outcome ; Xanthines/metabolism ; Xanthines/therapeutic use ; alpha 1-Antitrypsin/therapeutic use
    Chemical Substances Adrenal Cortex Hormones ; Macrolides ; Phosphodiesterase Inhibitors ; Xanthines ; alpha 1-Antitrypsin ; Morphine (76I7G6D29C) ; Azithromycin (83905-01-5) ; Theophylline (C137DTR5RG)
    Language English
    Publishing date 2021-04-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2149218-9
    ISSN 1558-5069 ; 1547-4127
    ISSN (online) 1558-5069
    ISSN 1547-4127
    DOI 10.1016/j.thorsurg.2021.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Rapport de la mission ERS 2007

    Roche, Nicolas / Godard, Philippe

    Stockholm, 15 - 19 septembre 2007

    (Revue des maladies respiratoires ; 25,Fev., Actualités)

    2008  

    Institution European Respiratory Society
    Author's details coord. par Nicolas Roche et Philippe Godard
    Series title Revue des maladies respiratoires ; 25,Fev., Actualités
    Collection
    Language French
    Size 75 S. : Ill., graph. Darst.
    Publisher Elsevier Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book
    HBZ-ID HT017136418
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Systemic Medications in Chronic Obstructive Pulmonary Disease: Use and Outcomes.

    Roche, Nicolas

    Clinics in chest medicine

    2020  Volume 41, Issue 3, Page(s) 485–494

    Abstract: Inhaled therapy remains the cornerstone of chronic obstructive pulmonary disease pharmacologic care, but some systemic treatments can be of help when the burden of the disease remains high. Azithromycin, phosphodiesterase-4 inhibitors, and mucoactive ... ...

    Abstract Inhaled therapy remains the cornerstone of chronic obstructive pulmonary disease pharmacologic care, but some systemic treatments can be of help when the burden of the disease remains high. Azithromycin, phosphodiesterase-4 inhibitors, and mucoactive agents can be used in such situations. The major difficulty remains in the identification of the optimal target populations. Another difficulty is to determine how these treatments should be positioned in the global treatment algorithm. For instance, should they be prescribed in addition to other antiinflammatory agents or should they replace them in some cases? Research is ongoing to identify new therapeutic targets.
    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Bronchodilator Agents/pharmacology ; Bronchodilator Agents/therapeutic use ; Humans ; Pulmonary Disease, Chronic Obstructive/drug therapy
    Chemical Substances Anti-Inflammatory Agents ; Bronchodilator Agents
    Language English
    Publishing date 2020-08-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 447455-7
    ISSN 1557-8216 ; 0272-5231
    ISSN (online) 1557-8216
    ISSN 0272-5231
    DOI 10.1016/j.ccm.2020.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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