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Article ; Online: Conductivity variations and changes in serum sodium concentration during dialysis related to monitor switching.

Maduell, Francisco / Broseta, José Jesús / Casals, Joaquim / Gómez, Miquel / Rodas, Lida M / Arias-Guillén, Marta / Vera, Manel / Fontseré, Néstor

Nefrologia

2024 Volume 43, Issue 6, Page(s) 750–756

Abstract: Introduction: The sodium gradient during hemodialysis sessions is one of the key factors in sodium balance in patients with dialysis-dependent chronic kidney disease; however, until the appearance of the new monitors with sodium modules, the differences ...

Abstract	Introduction: The sodium gradient during hemodialysis sessions is one of the key factors in sodium balance in patients with dialysis-dependent chronic kidney disease; however, until the appearance of the new monitors with sodium modules, the differences between prescribed and measured sodium have been understudied. The present study aimed to compare the impact on the measured conductivity and the initial and final plasma sodium after changing the 5008 Cordiax to the new 6008 Cordiax monitor. Material and methods: 106 patients on hemodialysis were included. Each patient underwent 2 dialysis sessions in which only the monitor was varied. The variables collected were dialysate, sodium and bicarbonate prescribed, real conductivity, initial and final plasma sodium measured, and the calculated sodium gradient (ΔPNa). Results: The change of dialysis monitor showed small but statistically significant differences in the initial (138.14mmol/L with 5008 vs. 138.81mmol/L with 6008) and final plasma sodium (139.58mmol/L vs. 140.97mmol/L), as well as in the actual conductivity obtained (13.97 vs. 14.1mS/cm). The ΔPNa also increased significantly. Conclusion: The change from 5008 to 6008 monitor is associated with increased conductivity, leading the patient to end the sessions with higher plasma sodium and ΔPNa. Knowing and confirming this change will allow us to individualize the sodium prescription and avoid possible undesirable effects. It could be the preliminary study to explore the new sodium biosensor incorporated into the new generation of monitors.
MeSH term(s)	Humans ; Renal Dialysis/adverse effects ; Sodium ; Dialysis Solutions
Chemical Substances	Sodium (9NEZ333N27) ; Dialysis Solutions
Language	English
Publishing date	2024-01-18
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2024.01.006
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Article ; Online: Is the VasQ™ device useful in the maturation of native arteriovenous fistulas? A single-center experience.

Fontseré, Néstor / Mestres, Gaspar / Yugueros, Xavier / Lozano, Valentín / Rodas, Lida María / Burrel, Marta / Maduell, Francisco

Nefrologia

2024 Volume 44, Issue 1, Page(s) 109–111

MeSH term(s)	Arteriovenous Shunt, Surgical ; Upper Extremity
Language	English
Publishing date	2024-02-28
Publishing country	Spain
Document type	Letter
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2024.02.010
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Article ; Online: Efficacy of systematic catheter locks solution of taurolidine/heparin versus taurolidine/urokinase in end-stage renal insufficiency stage 5D.

Fontseré, Néstor / Soriano, Alex / Mestres, Gaspar / Bermudez, Patricia / Zarco, Federico / Lozano, Valentín / Rodas, Lida / Broseta, Jose / Arias, Marta / Maduell, Francisco

Nefrologia

2023 Volume 42, Issue 5, Page(s) 611–613

MeSH term(s)	Humans ; Heparin/adverse effects ; Urokinase-Type Plasminogen Activator ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Catheters
Chemical Substances	Heparin (9005-49-6) ; Urokinase-Type Plasminogen Activator (EC 3.4.21.73) ; taurolidine (8OBZ1M4V3V)
Language	English
Publishing date	2023-01-18
Publishing country	Spain
Document type	Letter
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2021.02.013
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Article ; Online: Most recently developed polyester polymer alloy dialyzer: A new medium cut-off membrane?

Maduell, Francisco / Rodríguez-Espinosa, Diana / Rodas, Lida María / Gómez, Miquel / Arias-Guillén, Marta / Fontseré, Néstor / Vera, Manel / Del Carmen Salgado, Maria / Rico, Nayra / Broseta, José Jesús

Artificial organs

2024

Abstract: Background: New versions of the polyester polymer alloy (PEPA) membrane have appeared over the years, with increases in both the pore size and the amount of polyvinylpyrrolidone (PVP) to optimize hydrophilicity performance. This study aimed to assess ... ...

Abstract	Background: New versions of the polyester polymer alloy (PEPA) membrane have appeared over the years, with increases in both the pore size and the amount of polyvinylpyrrolidone (PVP) to optimize hydrophilicity performance. This study aimed to assess the efficacy of the most recently developed PEPA dialyzer, the FDY series, in hemodialysis (HD) modality in terms of uremic toxin removal and albumin loss and to compare it with that of several high-flux dialyzers currently used in HD and post-dilution hemodiafiltration (HDF) treatments. Methods: A prospective study was carried out in 21 patients. All patients underwent six dialysis sessions with the same routine dialysis parameters; only the dialyzer and/or the dialysis modality varied: FX80 in HD, FDY 180 in HD, Clearum HS17 in HDF, Elisio 19H in HDF, Vitapes 180 in HDF, and FX80 in post-dilution HDF. The reduction ratios (RR) of urea, creatinine, ß Results: Both membranes FDY and FX80 are high-flux dialyzers and are applied here in high-flux HD. The average RR of β Conclusions: The most recently developed PEPA dialyzers in the HD modality were as effective as all treatments in the HDF modality and were clearly superior to high-flux helixone HD treatment. These results confirm that this dialyzer should be categorized within the medium cut-off (MCO) membrane classification.
Language	English
Publishing date	2024-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	441812-8
ISSN	1525-1594 ; 0160-564X
ISSN (online)	1525-1594
ISSN	0160-564X
DOI	10.1111/aor.14726
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Zs.A 1463: Show issues

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Article ; Online: Comparison of efficacy and safety of the new generation helixone dialyzers.

Maduell, Francisco / Broseta, José Jesús / Rodríguez-Espinosa, Diana / Rodas, Lida María / Gómez, Miquel / Arias-Guillén, Marta / Fontseré, Néstor / Vera, Manel / Salgado, Maria Del Carmen / Rico, Nayra / Ramos, Rosa

Nefrologia

2024

Abstract: Introduction: New generation helixone dialyzers has recently been developed as part of the ongoing effort to improve dialyzer hemocompatibility and avoid adverse reactions to synthetic dialyzers. This study aimed to assess the performance and albumin ... ...

Abstract	Introduction: New generation helixone dialyzers has recently been developed as part of the ongoing effort to improve dialyzer hemocompatibility and avoid adverse reactions to synthetic dialyzers. This study aimed to assess the performance and albumin loss of this new dialyzer series in hemodiafiltration and compare it with the previous generation helixone series. Material and methods: A prospective study was conducted in 19 patients. Each patient underwent eight dialysis sessions with the same routine dialysis parameters; only the dialyzer varied: FX60 CorDiax, FX CorAL 60, FX600 CorDiax, FX CorAL 600, FX80 CorDiax, FX CorAL 80, FX800 CorDiax, and FX CorAL 800. The reduction ratios (RR) of urea, creatinine, ß Results: All treatments were well tolerated. The mean amount of replacement fluid ranged from 31 to 34 L. Comparison of dialysis treatments showed no differences between small molecules and even up to those the size of β2-microglobulins. Little differences were found between myoglobin, κFLC, prolactin, α Conclusion: The new generation helixone dialyzers series has been updated to minimise the risk of adverse reactions, while maintaining the effectiveness and albumin loss achieved by the previous most advanced helixone generation.
Language	English
Publishing date	2024-04-27
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2024.04.005
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Article: Aplastic crisis secondary to parvovirus B19 primoinfection as an infrequent cause of anemia in an immunocompetent, non-dialysis chronic kidney disease patient.

Guillen, Elena / Hermida, Evelyn / Rodas, Lida / Broseta, Jose J / Cases, Aleix

Clinical nephrology

2021 Volume 95, Issue 4, Page(s) 224–226

MeSH term(s)	Anemia/diagnosis ; Anemia/etiology ; Humans ; Parvoviridae Infections/complications ; Parvoviridae Infections/diagnosis ; Parvovirus B19, Human ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis
Language	English
Publishing date	2021-02-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	185101-9
ISSN	0301-0430
ISSN	0301-0430
DOI	10.5414/CN110150
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Zs.A 873: Show issues

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Article: Practical implementation and clinical benefits of the new automated dialysate sodium control biosensor.

Maduell, Francisco / Broseta, José J / Rodríguez-Espinosa, Diana / Casals, Joaquim / Escudero, Victor / Gomez, Miquel / Rodas, Lida M / Arias-Guillén, Marta / Vera, Manel / Fontseré, Néstor

Clinical kidney journal

2023 Volume 16, Issue 5, Page(s) 859–867

Abstract: Background: A key feature of dialysis treatment is the prescription of dialysate sodium (Na). This study aimed to describe the practical implementation of a new automated dialysate Na control biosensor and to assess its tolerance and the beneficial ... ...

Abstract	Background: A key feature of dialysis treatment is the prescription of dialysate sodium (Na). This study aimed to describe the practical implementation of a new automated dialysate Na control biosensor and to assess its tolerance and the beneficial clinical effects of isonatraemic dialysis. Methods: A prospective study was carried out in 86 patients who, along with their usual parameters, received the following five consecutive phases of treatment for 3 weeks each: phase 0: baseline 5008 machine; phases 1 and 2: 6008 machine without activation of the Na control biosensor and the same fixed individualized Na dialysate prescription or adjusted to obtain similar conductivity to phase 0; phases 3 and 4: activated Na control to isonatraemic dialysis (Na dialysate margins 135-141 or 134-142 mmol/L). Results: When the Na control was activated, the few episodes of cramps or hypotension disappeared when the lower dialysate Na margin was increased by 1 or 2 mmol/L. The activated Na control module showed significant differences compared with baseline and the non-activated Na module in final serum Na values, diffusive Na balance, and changes in pre- to postdialysis plasma Na values. The mean predialysis systolic blood pressure value was significantly lower in phase 4 than in phase 1. There were no significant differences in total Na balance in the four 6008 phases evaluated. Conclusions: The implementation of the automated dialysate Na control module is a useful new tool, which reduced the diffusive load of Na with good tolerance. The module had the advantages of reducing thirst, interdialytic weight gain and intradialytic plasma Na changes.
Language	English
Publishing date	2023-01-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2655800-2
ISSN	2048-8513 ; 2048-8505
ISSN (online)	2048-8513
ISSN	2048-8505
DOI	10.1093/ckj/sfad013
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Zs.A 6587: Show issues

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Article: Frailty in hemodialysis patients: results of a screening program and multidisciplinary interventions.

Arias-Guillén, Marta / Romano, Bárbara / Yuguero-Ortiz, Anna / López-Lazcano, Ana / Guerrero, Sonia / Villegas, Vanesa / Martínez, Mar / Clemente, Nuria / Gómez, Miquel / Rodas, Lida / Broseta, José Jesús / Quintela, Marta / Maduell, Francisco / Bayés, Beatriu

Clinical kidney journal

2023 Volume 16, Issue 11, Page(s) 2174–2184

Abstract: Background: The number of frail patients of advanced age with end-stage kidney disease (ESKD) undergoing hemodialysis is increasing globally. Here we evaluated a frailty screening program of ESKD patients starting hemodialysis, and subsequent ... ...

Abstract	Background: The number of frail patients of advanced age with end-stage kidney disease (ESKD) undergoing hemodialysis is increasing globally. Here we evaluated a frailty screening program of ESKD patients starting hemodialysis, and subsequent multidisciplinary interventions. Methods: This was a prospective observational study of ESKD patients in a hemodialysis program. Patients were evaluated for frailty (Fried frail phenotype) before and after a 12-month period. Patients followed standard clinical practice at our hospital, which included assessment and multidisciplinary interventions for nutritional (malnutrition-inflammation score, protein-energy wasting), physical [short physical performance battery (SPPB)] and psychological status. Results: A total of 167 patients (mean ± standard deviation age 67.8 ± 15.4 years) were screened for frailty, and 108 completed the program. At screening, 27.9% of the patients were frail, 40.0% pre-frail and 32.1% non-frail. Nutritional interventions (enrichment, oral nutritional supplements, intradialytic parenteral nutrition) resulted in stable nutritional status for most frail and pre-frail patients after 12 months. Patients following recommendations for intradialytic, home-based or combined physical exercise presented improved or stable in SPPB scores after 12 months, compared with those that did not follow recommendations, especially in the frail and pre-frail population ( Conclusions: Frailty screening, together with coordinated interventions by nutritionists, physiotherapists, psychologists and nurses, preserved the health status of ESKD patients starting hemodialysis. Frailty assessment helped in advising patients on individual nutritional, physical or psychological needs.
Language	English
Publishing date	2023-05-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2655800-2
ISSN	2048-8513 ; 2048-8505
ISSN (online)	2048-8513
ISSN	2048-8505
DOI	10.1093/ckj/sfad115
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Zs.A 6587: Show issues

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Article ; Online: Results of Salt Intake Restriction Monitored with the New Sodium Control Biosensor.

Maduell, Francisco / Cholbi, Ester / Morantes, Laura / Escudero-Saiz, Víctor Joaquín / Ollé, Júlia / Martínez-Chillarón, Marta / Rodas, Lida Maria / Rodríguez-Espinosa, Diana / Arias-Guillen, Marta / Vera, Manel / Fontseré, Néstor / Broseta, José Jesús

American journal of nephrology

2023 Volume 54, Issue 7-8, Page(s) 291–298

Abstract: Introduction: Adherence to a low-sodium (Na) diet is crucial in patients under hemodialysis, as it improves cardiovascular outcomes and reduces thirst and interdialytic weight gain. Recommended salt intake is lower than 5 g/day. The new 6008 CAREsystem ... ...

Abstract	Introduction: Adherence to a low-sodium (Na) diet is crucial in patients under hemodialysis, as it improves cardiovascular outcomes and reduces thirst and interdialytic weight gain. Recommended salt intake is lower than 5 g/day. The new 6008 CAREsystem monitors incorporate a Na module that offers the advantage of estimating patients' salt intake. The objective of this study was to evaluate the effect of dietary Na restriction for 1 week, monitored with the Na biosensor. Methods: A prospective study was conducted in 48 patients who maintained their usual dialysis parameters and were dialyzed with a 6008 CAREsystem monitor with activation of the Na module. Total Na balance, pre-/post-dialysis weight, serum Na (sNa), changes in pre- to post-dialysis sNa (ΔsNa), diffusive balance, and systolic and diastolic blood pressure were compared twice, once after 1 week of patients' usual Na diet and again after another week with more restricted Na intake. Results: Restricted Na intake increased the percentage of patients on a low-Na diet (<85 Na mmol/day) from 8% to 44%. Average daily Na intake decreased from 149 ± 54 to 95 ± 49 mmol, and interdialytic weight gain was reduced by 460 ± 484 g per session. More restricted Na intake also decreased pre-dialysis sNa and increased both intradialytic diffusive balance and ΔsNa. In hypertensive patients, reducing daily Na by more than 3 g Na/day lowered their systolic blood pressure. Conclusions: The new Na module allowed objective monitoring of Na intake, which in turn could permit more precise personalized dietary recommendations in patients under hemodialysis.
MeSH term(s)	Humans ; Sodium ; Sodium Chloride, Dietary ; Prospective Studies ; Renal Dialysis/methods ; Diet, Sodium-Restricted ; Blood Pressure ; Weight Gain
Chemical Substances	Sodium (9NEZ333N27) ; Sodium Chloride, Dietary
Language	English
Publishing date	2023-06-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	604540-6
ISSN	1421-9670 ; 0250-8095
ISSN (online)	1421-9670
ISSN	0250-8095
DOI	10.1159/000531521
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Zs.A 1635: Show issues

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Article ; Online: Acute hepatitis post arteriovenous graft thrombectomy of hemodialysis vascular access.

Rodríguez-Espinosa, Diana / Rodas, Lida / Cuadrado, Elena / Hermida, Evelyn / Piñeiro, Gastón Julio / Molina, Alicia / Broseta, José Jesús / Fontseré, Néstor / Maduell, Francisco

The journal of vascular access

2021 , Page(s) 1129729821998849

Abstract: The following paper reports the case of a woman on in-center hemodialysis through an arteriovenous graft, who attended with an acute vascular access thrombosis. Post percutaneous thrombectomy, the patient presented a rare case of self-limited acute ... ...

Abstract	The following paper reports the case of a woman on in-center hemodialysis through an arteriovenous graft, who attended with an acute vascular access thrombosis. Post percutaneous thrombectomy, the patient presented a rare case of self-limited acute hepatitis secondary to the revascularization procedure. We explain the probable trigger for this complication, its pathophysiology, management, and evolution.
Language	English
Publishing date	2021-06-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/1129729821998849
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