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  1. Article ; Online: Serum chloride as a marker of cardiovascular and all-cause mortality in chronic hemodialysis patients: 5-Year follow-up study.

    Valga, Francisco / Monzon, Tania / Vega-Diaz, Nicanor / Santana, Angelo / Moscol, Giancarlo / Ruiz-Santana, Sergio / Rodriguez-Perez, Jose Carlos

    Nefrologia

    2024  Volume 43 Suppl 2, Page(s) 47–56

    Abstract: Background: Hypochloremia has been associated with increased mortality in patients with hypertension, heart failure, sepsis, and chronic kidney disease (CKD). The pathophysiological mechanisms of this finding are not clear. There are no studies ... ...

    Abstract Background: Hypochloremia has been associated with increased mortality in patients with hypertension, heart failure, sepsis, and chronic kidney disease (CKD). The pathophysiological mechanisms of this finding are not clear. There are no studies describing an association between serum chloride levels (Cl
    Method: Retrospective cohort study of the incident population in our chronic outpatient hemodialysis program between January 1, 2016, and January 1, 2021 (N=374). Survival time was collected in all patients and analyzed using the Kaplan-Meyer method. A multivariate Cox regression model was performed to predict the probability of survival, applying a stepwise procedure.
    Results: During the median follow-up period of 20 months, 83 patients died. The 5-year overall survival rate for our patients was 45%. Both natremia and chloremia had no significant differences when compared by sex, vascular access, or etiology. There was an inverse correlation between Cl
    Conclusions: Lower Cl
    MeSH term(s) Humans ; Follow-Up Studies ; Chlorides ; Kidney Failure, Chronic/complications ; Retrospective Studies ; Renal Dialysis ; Hypertension/complications
    Chemical Substances Chlorides
    Language English
    Publishing date 2024-01-19
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2023.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inflammation and hemodialysis adequacy: are C-reactive protein levels influenced by the dose of dialysis?

    Valga, Francisco / Monzón, Tania / Vega-Diaz, Nicanor / Rodriguez-Perez, José Carlos / Ruiz-Santana, Sergio

    Nefrologia

    2022  Volume 42, Issue 2, Page(s) 163–170

    Abstract: Introduction: Chronic inflammation and the underlying cardiovascular comorbidity are still current problems in chronic hemodialysis patients. There are few studies comparing the "dialysis dose" with the degree of inflammation in the patient. Our main ... ...

    Abstract Introduction: Chronic inflammation and the underlying cardiovascular comorbidity are still current problems in chronic hemodialysis patients. There are few studies comparing the "dialysis dose" with the degree of inflammation in the patient. Our main objective was to determine whether there is a relationship between serum C-reactive protein (CRP) levels and the "dialysis dose" (Kt / V) using ionic dialysance.
    Methods: Multicenter cross-sectional study. 536 prevalent chronic hemodialysis patients were included. CRP levels, neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) were collected. Kt was obtained by ionic dialysance and urea distribution volume was calculated from the Watson's formula. The sample was divided into two groups, taking the median CRP as the cut-off point. Dialysis adequacy obtained in each group was compared. Finally, a logistic regression model was carried out to determine the variables with the greatest influence.
    Results: Median CRP was 4.10 mg/L (q25-q75: 1.67-10) and mean Kt/V was 1.48 ± 0.308. Kt/V was lower in the patients included in the high inflammation group (p = 0.01). In the multivariate logistic regression, the "high" levels of CRP were directly correlated with the Log INL (p < 0.001) and inversely proportional with serum albumin values (p = 0.014), Kt/V (p = 0.037) and serum iron (p < 0.001).
    Conclusion: The poorer adequacy in terms of dialysis doses, lower Kt / V values, may contribute to a higher degree of inflammation in chronic hemodialysis patients.
    MeSH term(s) C-Reactive Protein/analysis ; Cross-Sectional Studies ; Humans ; Inflammation ; Iron ; Renal Dialysis ; Serum Albumin/analysis ; Urea
    Chemical Substances Serum Albumin ; Urea (8W8T17847W) ; C-Reactive Protein (9007-41-4) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2022-04-30
    Publishing country Spain
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2021.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hypochloremia associated with a greater incidence of pneumonia in chronic hemodialysis patients with COVID-19: a center's experience.

    Valga, Francisco / Monzón, Tania / Vega-Diaz, Nicanor / Ruiz-Santana, Sergio / Aladro, Sara / Diallo-Saavedra, Rassoul / De la Flor, Jose Carlos / Rodriguez-Perez, José Carlos

    Nefrologia

    2024  Volume 44, Issue 2, Page(s) 290–292

    MeSH term(s) Humans ; COVID-19/complications ; Renal Dialysis ; Incidence ; Male ; Female ; Aged ; Middle Aged ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/blood ; Chlorides/blood ; Retrospective Studies ; SARS-CoV-2 ; Kidney Failure, Chronic/therapy ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/blood
    Chemical Substances Chlorides
    Language English
    Publishing date 2024-04-16
    Publishing country Spain
    Document type Letter
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2024.03.017
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  4. Article ; Online: SARS-CoV-2 screening in chronic hemodialysis patients in a third-level hospital and its peripheral centers: 'one hour less in the Canary Islands'.

    Valga, Francisco / Monzón, Tania / Vega-Diaz, Nicanor / Antón-Perez, Gloria / Rodriguez-Perez, José Carlos

    Nefrologia

    2021  Volume 41, Issue 4, Page(s) 470–471

    MeSH term(s) COVID-19 ; Hospitals ; Humans ; Renal Dialysis ; SARS-CoV-2 ; Spain/epidemiology
    Language English
    Publishing date 2021-10-05
    Publishing country Spain
    Document type Letter
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2020.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Inflammation and hemodialysis adequacy: Are C-reactive protein levels influenced by dialysis dose?

    Valga, Francisco / Monzón, Tania / Vega-Diaz, Nicanor / Rodriguez-Perez, José Carlos / Ruiz-Santana, Sergio

    Nefrologia

    2021  

    Abstract: Introduction: Chronic inflammation and the underlying cardiovascular comorbidity are still current problems in chronic hemodialysis patients. There are few studies comparing the "dialysis dose" (Kt/V) with the degree of inflammation in the patient. Our ... ...

    Title translation Inflamación y adecuación de la hemodiálisis: ¿están los niveles de proteína C reactiva influidos por la dosis de diálisis recibida?
    Abstract Introduction: Chronic inflammation and the underlying cardiovascular comorbidity are still current problems in chronic hemodialysis patients. There are few studies comparing the "dialysis dose" (Kt/V) with the degree of inflammation in the patient. Our main objective was to determine whether there is a relationship between serum C-reactive protein (CRP) levels and the Kt/V using ionic dialysance.
    Methods: Multicenter cross-sectional study. A total of 536 prevalent chronic hemodialysis patients were included. CRP levels, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were collected. Kt was obtained by ionic dialysance and urea distribution volume was calculated from the Watson's formula. The sample was divided into 2 groups, taking the median CRP as the cut-off point. Dialysis adequacy obtained in each group was compared. Finally, a logistic regression model was carried out to determine the variables with the greatest influence.
    Results: Median CRP was 4.10mg/L (q25-q75: 1.67-10) and mean Kt/V was 1.48±0.308. Kt/V was lower in the patients included in the high inflammation group (P=.01). In the multivariate logistic regression, the "high" levels of CRP were directly correlated with the Log neutrophil-lymphocyte ratio (P<.001) and inversely proportional with serum albumin values (P=.014), Kt/V (P=.037) and serum iron (P<.001).
    Conclusion: The poorer adequacy in terms of dialysis doses (lower Kt/V values) may contribute to a higher degree of inflammation in chronic hemodialysis patients.
    Language Spanish
    Publishing date 2021-07-05
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefro.2021.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Silent challenge: Early kidney transplant failure and cardiomyopathy.

    Santana-Estupiñán, Raquel / Valga, Francisco / Groba Marco, María Del Val / Quevedo-Reina, Juan Carlos / Bongiovanni, David / Rodríguez-Pérez, José Carlos

    Clinical case reports

    2022  Volume 10, Issue 10, Page(s) e6421

    Abstract: Differentiation of hypertrophic cardiomyopathy phenotypes is challenging but crucial for appropriate management. We report a case of myocardial oxalate deposition as an infrequent cause of infiltrative cardiomyopathy. ...

    Abstract Differentiation of hypertrophic cardiomyopathy phenotypes is challenging but crucial for appropriate management. We report a case of myocardial oxalate deposition as an infrequent cause of infiltrative cardiomyopathy.
    Language English
    Publishing date 2022-10-11
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6421
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  7. Article ; Online: The role of mTOR inhibitors in renal diseases.

    Rodríguez Pérez, J C

    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia

    2011  Volume 31, Issue 3, Page(s) 251–255

    MeSH term(s) Humans ; Kidney Diseases/drug therapy ; Kidney Diseases/etiology ; Sirolimus/therapeutic use ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/physiology
    Chemical Substances TOR Serine-Threonine Kinases (EC 2.7.1.1) ; Sirolimus (W36ZG6FT64)
    Language Spanish
    Publishing date 2011
    Publishing country Spain
    Document type Comment ; Editorial
    ZDB-ID 632512-9
    ISSN 1989-2284 ; 0211-6995
    ISSN (online) 1989-2284
    ISSN 0211-6995
    DOI 10.3265/Nefrologia.pre2011.Apr.10947
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2773: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 56: Show issues

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  8. Article ; Online: A new inflammatory-microthrombotic syndrome as an explanation for thrombotic complications in patients with COVID-19.

    Valga, Francisco / Vega-Díaz, Nicanor / Macía, Manuel / Rodríguez-Pérez, José Carlos

    Revista espanola de cardiologia (English ed.)

    2020  Volume 74, Issue 1, Page(s) 115–116

    MeSH term(s) COVID-19/complications ; COVID-19/epidemiology ; Global Health ; Humans ; Incidence ; Pandemics ; SARS-CoV-2 ; Syndrome ; Thrombosis/epidemiology ; Thrombosis/etiology
    Keywords covid19
    Language Spanish
    Publishing date 2020-10-02
    Publishing country Spain
    Document type Letter
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2020.08.021
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  9. Article: Targeting complement in severe coronavirus disease 2019 to address microthrombosis.

    Valga, Francisco / Vega-Díaz, Nicanor / Macia, Manuel / Monzón, Tania / Rodriguez-Perez, Jose C

    Clinical kidney journal

    2020  Volume 13, Issue 3, Page(s) 477–479

    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfaa095
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6587: Show issues Location:
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  10. Article ; Online: Cribado de SARS-CoV-2 de pacientes en hemodiálisis crónica en un hospital de tercer nivel y sus centros periféricos: una hora menos en Canarias.

    Valga, Francisco / Monzón, Tania / Vega-Díaz, Nicanor / Antón-Pérez, Gloria / Rodríguez-Pérez, José Carlos

    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia

    2020  Volume 41, Issue 4, Page(s) 470–471

    Title translation SARS-CoV-2 screening in chronic hemodialysis patients in a third-level hospital and its peripheral centers:'one hour less in the Canary Islands'.
    Language Spanish
    Publishing date 2020-10-13
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 632512-9
    ISSN 1989-2284 ; 0211-6995
    ISSN (online) 1989-2284
    ISSN 0211-6995
    DOI 10.1016/j.nefro.2020.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2773: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 56: Show issues

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