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  1. Article ; Online: User Perception of New E-Health Challenges: Implications for the Care Process.

    González-Revuelta, María Esther / Novas, Nuria / Gázquez, Jose Antonio / Rodríguez-Maresca, Manuel Ángel / García-Torrecillas, Juan Manuel

    International journal of environmental research and public health

    2022  Volume 19, Issue 7

    Abstract: Establishing new models of health care and new forms of professional health-patient communication are lines of development in the field of health care. The onset of the COVID-19 pandemic has accelerated the evolution of information systems and ... ...

    Abstract Establishing new models of health care and new forms of professional health-patient communication are lines of development in the field of health care. The onset of the COVID-19 pandemic has accelerated the evolution of information systems and communication platforms to guarantee continuity of care and compliance with social distancing measures. Our objective in this article was, firstly, to know the expectations of patients treated in the healthcare processes "cervical cancer" and "pregnancy, childbirth and puerperium" regarding online access to their clinical history and follow-up in the care process. Secondly, we analyzed times involved in the cervical cancer process to find points of improvement in waiting times when digital tools were used for communication with the patient. A descriptive cross-sectional study was carried out on 120 women included in any of the aforementioned processes using a hetero-administered questionnaire. The analysis of times was carried out using the Business Intelligence tool Biwer Analytics
    MeSH term(s) COVID-19/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Pandemics ; Perception ; Telemedicine
    Language English
    Publishing date 2022-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19073875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparison of Analytical Values D-Dimer, Glucose, Ferritin and C-Reactive Protein of Symptomatic and Asymptomatic COVID-19 Patients.

    Pérez-García, Nerea / García-González, Jessica / Requena-Mullor, Mar / Rodríguez-Maresca, Manuel Ángel / Alarcón-Rodríguez, Raquel

    International journal of environmental research and public health

    2022  Volume 19, Issue 9

    Abstract: Those infected by COVID-19 develop various kinds of complications with varying degrees of severity. For this reason, it is necessary to evaluate its analytical values to predict and reduce the risks and complications derived from this pathology. A cross- ... ...

    Abstract Those infected by COVID-19 develop various kinds of complications with varying degrees of severity. For this reason, it is necessary to evaluate its analytical values to predict and reduce the risks and complications derived from this pathology. A cross-sectional study was carried out a population in Almeria (south-eastern Spain) who had a positive Polymerase Chain Reaction test result from 1 March 2020 to 30 November 2020. The study involved 4575 patients, with 1346 who were asymptomatic, 1653 mildly symptomatic (no hospitalisation needed) and 1576 severely symptomatic (symptomatic patients hospitalised). Laboratory values for D-dimer, glucose, serum ferritin, and C-reactive protein were analysed. The mean age of the participants in the study was 53.60 (16.89) years old. A total of 70.6% of the patients were symptomatic, of which 36.1% had mild symptoms. For all of the laboratory predictors analysed (D-dimer, glucose, serum ferritin, and C-reactive protein), it was found that severe alterations in the parameters were more frequent in severely symptomatic patients with statistically significant differences (p < 0.001), although these alterations also occurred in asymptomatic patients. Age correlated with analytical values (D-dimer, glucose, serum ferritin, and C-reactive protein) with statistically significant differences. Patients with severe symptoms presented alterations in the analytical values of D-dimer, glucose, serum ferritin, and C-reactive protein. Asymptomatic patients presented alterations in the analysed parameters, though with less frequency and severity than patients with severe symptoms.
    MeSH term(s) Biomarkers ; C-Reactive Protein/analysis ; COVID-19/diagnosis ; Cross-Sectional Studies ; Ferritins ; Fibrin Fibrinogen Degradation Products ; Glucose ; Humans ; Middle Aged ; Retrospective Studies ; SARS-CoV-2
    Chemical Substances Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D ; C-Reactive Protein (9007-41-4) ; Ferritins (9007-73-2) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-04-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19095354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What is essential remains invisible to the eyes? Blood pressure cuffs colonized by bacterial diversity.

    Garrido-Molina, José Miguel / Márquez-Hernández, Verónica V / García-Viola, Alba / Rodríguez-Maresca, Manuel Ángel / Del Águila, Javier García / Gutiérrez-Puertas, Lorena

    International microbiology : the official journal of the Spanish Society for Microbiology

    2022  Volume 26, Issue 2, Page(s) 389–396

    Abstract: Using sphygmomanometers to measure blood pressure is a common practice in the healthcare context. The disinfection and maintenance of these devices is essential in clinical practice to prevent the proliferation of microorganisms. The aim of this study ... ...

    Abstract Using sphygmomanometers to measure blood pressure is a common practice in the healthcare context. The disinfection and maintenance of these devices is essential in clinical practice to prevent the proliferation of microorganisms. The aim of this study was to determine the presence of pathogenic microorganisms in sphygmomanometer cuffs in the clinical setting. A cross-sectional study was carried out. Five types of healthcare centers, selected through convenience sampling, participated in this study. Samples were collected from the inside of sphygmomanometer cuffs, and labeled and delivered to the laboratory for analysis. The samples were incubated in an oven at 35.5 °C for 24 h. A total CFU count was carried out on the plates that were cataloged as positive. Colonies that showed growth were identified using the matrix-assisted laser desorption/ionization-mass spectrometry technology. Of the total sample, (N = 372), 69.1% were positive and were isolated. In 30.9% (n = 115), no bacterial development was found within 48 h. A total of 257 microorganisms were found. The mean number of colony-forming units was 29.62 (SD = 32.33). The socio-health centers had the highest amount of bacterial contamination in the cuffs. In regards to the type of microorganisms, 31.5% (n = 81) found were Bacillus cereus, followed by 26.8% (n = 69) of Staphylococcus hominis and 9.7% (n = 25) were Pantoea agglomerans, among others. Statistically significant differences were found between the type of microorganism and the hours elapsed since the last disinfection (X
    MeSH term(s) Blood Pressure/physiology ; Cross-Sectional Studies ; Blood Pressure Determination/methods ; Sphygmomanometers/microbiology ; Bacillus cereus
    Language English
    Publishing date 2022-12-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1454951-7
    ISSN 1618-1905 ; 1139-6709
    ISSN (online) 1618-1905
    ISSN 1139-6709
    DOI 10.1007/s10123-022-00308-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Emergency department contribution to HCV elimination in the Iberian Peninsula.

    Buti, Maria / Vaz-Pinto, Inês / Magno Pereira, Vítor / Casado, Marta / Llaneras, Jordi / Barreira, Ana / Esteves, Catarina / Guimarães, Mafalda / Gorgulho, Ana / Mourão, Tomás / Xavier, Elisa / Jasmins, Luís / Reis, Ana Paula / Faria, Nancy / Freitas, Bruno / Andrade, Graça / Camelo-Castillo, Anny / Rodríguez-Maresca, Manuel Ángel / Carrodeguas, Alba /
    Medina, Diogo / Esteban, Rafael

    International journal of emergency medicine

    2024  Volume 17, Issue 1, Page(s) 5

    Abstract: Background: Undiagnosed cases of hepatitis C virus (HCV) infection result in significant morbidity and mortality, further transmission, and increased public health costs. Testing in emergency departments (EDs) is an opportunity to expand HCV screening. ... ...

    Abstract Background: Undiagnosed cases of hepatitis C virus (HCV) infection result in significant morbidity and mortality, further transmission, and increased public health costs. Testing in emergency departments (EDs) is an opportunity to expand HCV screening. The goal of this project was to increase the proportion of eligible patients screened for HCV in urban areas.
    Methods: An opportunistic automated HCV screening program was implemented in the EDs of 4 public hospitals in Spain and Portugal at different periods between 2018 and 2023. HCV prevalence was prospectively evaluated, and single-step or reflex testing was used for confirmation in the same sample.
    Results: More than 90% of the population eligible for testing were screened in the participating centers. We found HCV antibody seroprevalence rates ranging from 0.6 to 3.9%, with between 19 and 53% of viremic individuals.
    Conclusions: Opportunistic HCV screening in EDs is feasible, does not disrupt ED activities, is highly effective in increasing diagnosis, and contributes to WHO's HCV elimination goals.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2411462-5
    ISSN 1865-1380 ; 1865-1372
    ISSN (online) 1865-1380
    ISSN 1865-1372
    DOI 10.1186/s12245-023-00570-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effectiveness of Electronic Guidelines (GERH

    Navarro-Gómez, Paola / Gutierrez-Fernandez, Jose / Rodriguez-Maresca, Manuel Angel / Olvera-Porcel, Maria Carmen / Sorlozano-Puerto, Antonio

    Antibiotics (Basel, Switzerland)

    2020  Volume 9, Issue 8

    Abstract: The objective of the study was to evaluate the capacity of ... ...

    Abstract The objective of the study was to evaluate the capacity of GERH
    Language English
    Publishing date 2020-08-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics9080521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The CARBA-MAP study: national mapping of carbapenemases in Spain (2014-2018).

    Gracia-Ahufinger, Irene / López-González, Laura / Vasallo, Francisco José / Galar, Alicia / Siller, María / Pitart, Cristina / Bloise, Iván / Torrecillas, Miriam / Gijón-Cordero, Desirée / Viñado, Belén / Castillo-García, Javier / Campo, Rainer / Mulet, Xavier / Madueño-Alonso, Ana / Chamizo-López, Francisco Javier / Arrastia-Erviti, Maitane / Galán-Sánchez, Fátima / Fernández-Quejo, Melisa / Rodríguez-Díaz, Juan Carlos /
    Gutiérrez-Zufiaurre, María Nieves / Rodríguez-Maresca, Manuel Angel / Ortega-Lafont, María Del Pilar / Yagüe-Guirao, Genoveva / Chaves-Blanco, Lucía / Colomina-Rodríguez, Javier / Vidal-Acuña, María Reyes / Portillo, María Eugenia / Franco-Álvarez de Luna, Francisco / Centelles-Serrano, María José / Azcona-Gutiérrez, José Manuel / Delgado-Iribarren García Campero, Alberto / Rey-Cao, Sonia / Muñoz, Patricia / Calvo-Montes, Jorge / Zboromyrska, Yuliya / Grandioso, David / Càmara, Jordi / Cantón, Rafael / Larrosa-Escartín, Nieves / Díaz-Regañón, Jazmín / Martínez-Martínez, Luis

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1247804

    Abstract: Introduction: Infections caused by carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant : Methods: A national, retrospective, cross-sectional multicenter study was performed. The study included the first isolate per patient and year ... ...

    Abstract Introduction: Infections caused by carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant
    Methods: A national, retrospective, cross-sectional multicenter study was performed. The study included the first isolate per patient and year obtained from clinical samples and obtained for diagnosis of infection in hospitalized patients. A structured questionnaire was completed by the participating centers using the REDCap platform, and results were analyzed using IBM SPSS Statistics 29.0.0.
    Results: A total of 2,704 carbapenemase-producing microorganisms were included, for which the type of carbapenemase was determined in 2692 cases: 2280 CPE (84.7%) and 412 CPPA (15.3%), most often using molecular methods and immunochromatographic assays. Globally, the most frequent types of carbapenemase in Enterobacterales and
    Discussion: Data from this study help to understand the situation and evolution of the main species of CPE and CPPA in Spain, with practical implications for control and optimal treatment of infections caused by these multi-drug resistant organisms.
    Language English
    Publishing date 2023-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1247804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Simultaneous analysis of antibiotics in biological samples by ultra high performance liquid chromatography-tandem mass spectrometry.

    Cazorla-Reyes, Rocío / Romero-González, Roberto / Frenich, Antonia Garrido / Rodríguez Maresca, Manuel Angel / Martínez Vidal, José Luis

    Journal of pharmaceutical and biomedical analysis

    2014  Volume 89, Page(s) 203–212

    Abstract: A rapid and reliable multiclass method was developed for the simultaneous analysis of 21 antibiotics (beta-lactams, aminoglycosides, penicillins, cephalosporins, carbapenems or quinolones) in urine, serum, cerebrospinal fluid (CSF) and bronchial ... ...

    Abstract A rapid and reliable multiclass method was developed for the simultaneous analysis of 21 antibiotics (beta-lactams, aminoglycosides, penicillins, cephalosporins, carbapenems or quinolones) in urine, serum, cerebrospinal fluid (CSF) and bronchial aspirations by ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS). Prior to chromatographic determination, the analytes were extracted from human biological fluids by simple sample treatments, which imply dilution, liquefaction, or protein precipitation. Several chromatographic conditions were optimized in order to obtain a fast separation (<6min for each chromatographic run). MS/MS conditions were evaluated in order to increase selectivity and sensitivity and all compounds were detected in electrospray (ESI) positive ion mode, except clavulanic acid and sulbactam, which were monitored in negative ion mode. The developed method was validated in terms of linearity, selectivity, limits of detection (LODs) and quantification (LOQs), trueness, repeatability and interday precision. The LOQs ranged from 0.01 to 1.00mg/L for urine, serum and CSF. In case of bronchial aspirations, the LOQs were between 0.02 and 0.67mg/kg. In all matrices the recovery results were in the range 70-120% and interday precision was lower than 25%. Finally, the optimized method was applied to the analysis of biological samples from 10 patients in the intensive care unit (ICU) of a hospital located in Almeria (Spain). Several antibiotics (e.g., amoxicillin, tobramycin, levofloxacin, or linezolid) were found in the studied samples, observing that the highest concentrations were obtained in urine samples.
    MeSH term(s) Anti-Bacterial Agents/blood ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/urine ; Bronchi/chemistry ; Cerebrospinal Fluid/chemistry ; Chromatography, High Pressure Liquid/methods ; Humans ; Limit of Detection ; Tandem Mass Spectrometry/methods
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2014-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604917-5
    ISSN 1873-264X ; 0731-7085
    ISSN (online) 1873-264X
    ISSN 0731-7085
    DOI 10.1016/j.jpba.2013.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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