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  1. Article: Millet: A "Gluten-free" and "Healthy" Cereal With the Potential to Induce Anaphylaxis.

    Baptista Serna, L / Sastre, B / Rodrigo-Muñoz, J M / Valverde-Monge, M / Sastre, J / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2022  Volume 33, Issue 2, Page(s) 145–146

    MeSH term(s) Humans ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Edible Grain/adverse effects ; Millets ; Seeds
    Language English
    Publishing date 2022-05-18
    Publishing country Spain
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: What Is the Limit? Anaphylaxis After Intake of a Whey Sport Supplement Shake by a Cow's Milk-Tolerant Patient.

    Villalobos-Vilda, C / Lendínez, M A / Lorente-Sorolla, C / Rodrigo-Muñoz, J M / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2022  Volume 33, Issue 3, Page(s) 228–229

    MeSH term(s) Animals ; Female ; Cattle ; Humans ; Milk/adverse effects ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Whey ; Whey Proteins/adverse effects ; Milk Proteins/adverse effects ; Allergens ; Milk Hypersensitivity
    Chemical Substances Whey Proteins ; Milk Proteins ; Allergens
    Language English
    Publishing date 2022-06-14
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Anaphylaxis After Mango Fruit Intake: Identification of New Allergens.

    Ortega-Martín, L / Sastre, B / Rodrigo-Muñoz, J M / Cañas, J A / Valverde-Monge, M / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2021  Volume 32, Issue 5, Page(s) 401–403

    MeSH term(s) Allergens ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Fruit/adverse effects ; Humans ; Mangifera/adverse effects ; Plant Proteins
    Chemical Substances Allergens ; Plant Proteins
    Language English
    Publishing date 2021-11-16
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Stability of Asthma Control Implies No Changes in microRNAs Expression.

    Rial, M J / Rodrigo Muñoz, J M / Sastre, B / Sastre, J / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2019  Volume 29, Issue 5, Page(s) 388–389

    MeSH term(s) Anti-Asthmatic Agents/administration & dosage ; Anti-Asthmatic Agents/adverse effects ; Anti-Asthmatic Agents/therapeutic use ; Asthma/diagnosis ; Asthma/drug therapy ; Asthma/genetics ; Biomarkers ; Circulating MicroRNA/blood ; Gene Expression Regulation/drug effects ; Humans ; MicroRNAs/blood ; MicroRNAs/genetics ; Respiratory Function Tests
    Chemical Substances Anti-Asthmatic Agents ; Biomarkers ; Circulating MicroRNA ; MicroRNAs
    Language English
    Publishing date 2019-05-07
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Avocado Allergy: Identification of a New Allergen.

    Privitera-Torres, M / González-Moreno, A / Pérez-Codesido, S / Del Pozo Abejón, V / Rodrigo Muñoz, J M / Cañas Mañas, J A / Alonso-Díaz-de Durana, M D

    Journal of investigational allergology & clinical immunology

    2022  Volume 33, Issue 3, Page(s) 236–237

    MeSH term(s) Humans ; Allergens ; Persea ; Food Hypersensitivity/diagnosis
    Chemical Substances Allergens
    Language English
    Publishing date 2022-07-29
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Eosinophil Response Against Classical and Emerging Respiratory Viruses: COVID-19.

    Rodrigo-Muñoz, J M / Sastre, B / Cañas, J A / Gil-Martínez, M / Redondo, N / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2020  Volume 31, Issue 2, Page(s) 94–107

    Abstract: Eosinophils were discovered more than 140 years ago. These polymorphonuclear leukocytes have a very active metabolism and contain numerous intracellular secretory granules that enable multiple effects on both health and disease status. Classically, ... ...

    Abstract Eosinophils were discovered more than 140 years ago. These polymorphonuclear leukocytes have a very active metabolism and contain numerous intracellular secretory granules that enable multiple effects on both health and disease status. Classically, eosinophils have been considered important immune cells in the pathogenesis of inflammatory processes (eg, parasitic helminth infections) and allergic or pulmonary diseases (eg, asthma) and are always associated with a type 2 immune response. Furthermore, in recent years, eosinophils have been linked to the immune response by conferring host protection against fungi, bacteria, and viruses, which they recognize through several molecules, such as toll-like receptors and the retinoic acid-inducible gene 1-like receptor. The immune protection provided by eosinophils is exerted through multiple mechanisms and properties. Eosinophils contain numerous cytoplasmatic granules that release cationic proteins, cytokines, chemokines, and other molecules, all of which contribute to their functioning. In addition to the competence of eosinophils as effector cells, their capabilities as antigen-presenting cells enable them to act in multiple situations, thus promoting diverse aspects of the immune response. This review summarizes various aspects of eosinophil biology, with emphasis on the mechanisms used and roles played by eosinophils in host defence against viral infections and response to vaccines. The review focuses on respiratory viruses, such as the new coronavirus, SARS-CoV-2.
    MeSH term(s) Animals ; COVID-19/immunology ; Eosinophils/immunology ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A case of anaphylaxis after oats ingestion: Research for new allergens.

    González-Afonso, M / Cañas, J A / Sastre, B / Rodrigo-Muñoz, J M / Mendoza-Alvarez, A / Martinez-Tadeo, J A / González Colino, C E / Hernández-Santana, G L / Rodriguez-Plata, E / Barrios-Recio, J / Del Pozo, V / García Robaina, J C

    Journal of investigational allergology & clinical immunology

    2022  

    Language English
    Publishing date 2022-03-02
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Long-term immune response accompanies clinical outcomes in severe asthmatics treated with anti-IL-5/IL-5R biologics.

    Lorente-Sorolla, C / Bernaola, J / Sánchez-Mellado, D / Gil-Martínez, M / Naharro-González, S / Betancor, D / Fernández-Nieto, M / Pinillos-Robles, E J / Santillán Coello, J M / Villacampa-Aubá, J M / Rodríguez-Nieto, M J / Sastre, J / Valverde-Monge, M / Rodrigo-Muñoz, J M / Del Pozo, V

    Allergy

    2023  Volume 78, Issue 11, Page(s) 3027–3031

    Language English
    Publishing date 2023-08-29
    Publishing country Denmark
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Eosinophils: Old Players in a New Game.

    Sastre, B / Rodrigo-Muñoz, J M / Garcia-Sanchez, D A / Cañas, J A / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2018  Volume 28, Issue 5, Page(s) 289–304

    Abstract: Eosinophils are terminal polymorphonuclear cells with a high number of cytoplasmic granules that originate in bone marrow. Some are exosomes, which contain multiple molecules, such as specific eosinophilic proteins, cytokines, chemokines, enzymes, and ... ...

    Abstract Eosinophils are terminal polymorphonuclear cells with a high number of cytoplasmic granules that originate in bone marrow. Some are exosomes, which contain multiple molecules, such as specific eosinophilic proteins, cytokines, chemokines, enzymes, and lipid mediators that contribute to the effector role of these cells. Moreover, exosomes present a large number of receptors that allow them to interact with multiple cell types. Eosinophils play an important role in defense against infestations and are a key element in asthma and allergic diseases. Eosinophils are recruited to the inflamed area in response to stimuli, modulating the immune response through the release to the extracellular medium of their granule-derived content. Various mechanisms of degranulation have been identified. Polymorphonuclear leukocytes contain multivesicular bodies that generate exosomes that are secreted into the extracellular environment. Eosinophilic exosomes participate in multiple processes and mechanisms. Eosinophils participate actively in asthma and are hallmarks of the disease. The cells migrate to the inflammatory focus and contribute to epithelial damage and airway remodeling. Given their relevance in this pathology, new therapeutic tools have been developed that target mainly eosinophils and their receptors. In this manuscript, we provide a global, updated vision of the biology of eosinophils and the role of eosinophils in respiratory diseases, particularly asthma. We also summarize asthma treatments linked to eosinophils and new therapeutic strategies based on biological products in which eosinophils and their receptors are the main targets.
    MeSH term(s) Animals ; Asthma/immunology ; Chemokines/immunology ; Cytokines/immunology ; Eosinophils/immunology ; Humans ; Hypersensitivity/immunology ; Inflammation/immunology
    Chemical Substances Chemokines ; Cytokines
    Language English
    Publishing date 2018-07-30
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Doxylamine Allergy in a Pregnant Woman: Suitability of the Basophil Activation Test.

    Rial, M J / Fernández-Nieto, M / Rodrigo-Muñoz, J M / Sastre, B / Sastre, J / Del Pozo, V

    Journal of investigational allergology & clinical immunology

    2018  Volume 28, Issue 6, Page(s) 433–434

    MeSH term(s) Adult ; Basophils/immunology ; Doxylamine/adverse effects ; Doxylamine/immunology ; Female ; Humans ; Hypersensitivity/immunology ; Pregnancy
    Chemical Substances Doxylamine (95QB77JKPL)
    Language English
    Publishing date 2018-12-07
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    DOI 10.18176/jiaci.0311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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