LIVIVO - Search results -

Search results

Result 1 - 10 of total 189

Search options

Article ; Online: Definitions, phenotypes, and subphenotypes in acute kidney injury-Moving towards precision medicine.

Rodrigues, Camila Eleuterio / Endre, Zoltán H

2022 Volume 28, Issue 2, Page(s) 83–96

Abstract: The current definition of acute kidney injury (AKI) is generic and, based only on markers of function, is unsuitable for guiding individualized treatment. AKI is a complex syndrome with multiple presentations and causes. Targeted AKI management will only ...

Abstract	The current definition of acute kidney injury (AKI) is generic and, based only on markers of function, is unsuitable for guiding individualized treatment. AKI is a complex syndrome with multiple presentations and causes. Targeted AKI management will only be possible if different phenotypes and subphenotypes of AKI are recognised, based on causation and related pathophysiology. Molecular signatures to identify subphenotypes are being recognised, as specific biomarkers reveal activated pathways. Assessment of individual clinical risk needs wider dissemination to allow identification of patients at high risk of AKI. New and more timely markers for glomerular filtration rate (GFR) are available. However, AKI diagnosis and classification should not be limited to GFR, but include tubular function and damage. Combining damage and stress biomarkers with functional markers enhances risk prediction, and identifies a population enriched for clinical trials targeting AKI. We review novel developments and aim to encourage implementation of these new techniques into clinical practice as a strategy for individualizing AKI treatment akin to a precision medicine-based approach.
MeSH term(s)	Humans ; Precision Medicine/adverse effects ; Creatinine ; Phenotype ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy ; Biomarkers
Chemical Substances	Creatinine (AYI8EX34EU) ; Biomarkers
Language	English
Publishing date	2022-11-25
Publishing country	Australia
Document type	Journal Article ; Review
ZDB-ID	1303661-0
ISSN	1440-1797 ; 1320-5358
ISSN (online)	1440-1797
ISSN	1320-5358
DOI	10.1111/nep.14132
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 4822: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: Convergent Mutations and Single Nucleotide Variants in Mitochondrial Genomes of Modern Humans and Neanderthals.

Ferreira, Renata C / Rodrigues, Camila R / Broach, James R / Briones, Marcelo R S

International journal of molecular sciences

2024 Volume 25, Issue 7

Abstract: The genetic contributions of Neanderthals to the modern human genome have been evidenced by the comparison of present-day human genomes with paleogenomes. Neanderthal signatures in extant human genomes are attributed to intercrosses between Neanderthals ... ...

Abstract	The genetic contributions of Neanderthals to the modern human genome have been evidenced by the comparison of present-day human genomes with paleogenomes. Neanderthal signatures in extant human genomes are attributed to intercrosses between Neanderthals and archaic anatomically modern humans (AMHs). Although Neanderthal signatures are well documented in the nuclear genome, it has been proposed that there is no contribution of Neanderthal mitochondrial DNA to contemporary human genomes. Here we show that modern human mitochondrial genomes contain 66 potential Neanderthal signatures, or Neanderthal single nucleotide variants (N-SNVs), of which 36 lie in coding regions and 7 result in nonsynonymous changes. Seven N-SNVs are associated with traits such as cycling vomiting syndrome, Alzheimer's disease and Parkinson's disease, and two N-SNVs are associated with intelligence quotient. Based on recombination tests, principal component analysis (PCA) and the complete absence of these N-SNVs in 41 archaic AMH mitogenomes, we conclude that convergent evolution, and not recombination, explains the presence of N-SNVs in present-day human mitogenomes.
MeSH term(s)	Humans ; Animals ; Neanderthals/genetics ; Genome, Mitochondrial ; Mutation ; Alzheimer Disease ; Nucleotides
Chemical Substances	Nucleotides
Language	English
Publishing date	2024-03-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25073785
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Metal-ceramic and porcelain-veneered lithium disilicate crowns: a stress profile comparison using a viscoelastic finite element model.

Dhital, Sukirti / Rodrigues, Camila / Zhang, Yu / Kim, Jeongho

Computer methods in biomechanics and biomedical engineering

2021 Volume 25, Issue 4, Page(s) 412–423

Abstract: Metal-ceramics (MC) are one of the oldest dental restorative systems, which are considered to be the gold standard for full crown restoration. Porcelain-veneered lithium disilicate (PVLD), on the other hand, are newer material systems that have shown ... ...

Abstract	Metal-ceramics (MC) are one of the oldest dental restorative systems, which are considered to be the gold standard for full crown restoration. Porcelain-veneered lithium disilicate (PVLD), on the other hand, are newer material systems that have shown high survival rate in clinical follow-ups but needs to be studied more. This study compares the stresses developed in the single crowns made from newer PVLD system against those with MC configuration. For this comparison, influence of the layer thickness and cooling rates is also taken into consideration. An experimentally validated viscoelastic finite element model (VFEM) has been developed to predict the stress profile in these systems. Three-dimensional rotationally symmetric crowns were analyzed using this validated model for both material systems, three veneer to core thickness ratios (2:1, 1:1, 1:2), and two cooling rates: slow cooling at 1.74E-5 W/mm
MeSH term(s)	Ceramics ; Crowns ; Dental Porcelain ; Dental Stress Analysis ; Finite Element Analysis ; Materials Testing ; Zirconium
Chemical Substances	lithia disilicate ; Dental Porcelain (12001-21-7) ; Zirconium (C6V6S92N3C)
Language	English
Publishing date	2021-07-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2071764-7
ISSN	1476-8259 ; 1025-5842
ISSN (online)	1476-8259
ISSN	1025-5842
DOI	10.1080/10255842.2021.1955869
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6374: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide.

Rodrigues, Camila / Percival, Susan S

Nutrients

2019 Volume 11, Issue 2

Abstract: Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H₂S), an endogenous, gaseous, signaling transmitter, has also ... ...

Abstract	Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H₂S), an endogenous, gaseous, signaling transmitter, has also been shown to be involved in the regulation of inflammation. Recent studies have shown that sulfur-containing compounds from garlic have beneficial effects in attenuating outcomes associated with cardiovascular disease and inflammation by a mechanism that may be related to the H₂S signaling pathway. In this review, we summarize the main functions of glutathione (GSH), garlic derivatives and H₂S and their role in the immune response and impact on health and disease.
MeSH term(s)	Animals ; Garlic ; Glutathione/pharmacology ; Humans ; Hydrogen Sulfide/pharmacology ; Immunologic Factors/pharmacology ; Plant Extracts/pharmacology
Chemical Substances	Immunologic Factors ; Plant Extracts ; Glutathione (GAN16C9B8O) ; Hydrogen Sulfide (YY9FVM7NSN)
Language	English
Publishing date	2019-01-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11020295
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Association between PAH and plastic fragments on Brazilian coast beaches: a baseline assessment.

Branco, Felipe Ohade Lopes / Pegado, Tamyris / Giarrizzo, Tommaso / Rodrigues, Camila Carneiro Dos Santos / Corrêa, José Augusto Martins

Environmental science and pollution research international

2023 Volume 30, Issue 58, Page(s) 121895–121907

Abstract: Plastic materials have many destinies on the environment, and one of them is its continuous fragmentation, originating microplastics (MP). MP act as an adsorption surface for organic pollutants like polycyclic aromatic hydrocarbons (PAH). Due to its ... ...

Abstract	Plastic materials have many destinies on the environment, and one of them is its continuous fragmentation, originating microplastics (MP). MP act as an adsorption surface for organic pollutants like polycyclic aromatic hydrocarbons (PAH). Due to its toxic and harmful properties, 16 PAH are defined as priorities in studies. Several works have evaluated the occurrence of MP and PAH individually in environmental matrices, but just a few have investigated their association. The present study aims to investigate PAH occurrence, sources, and concentration in MP from beach sediments of eight Brazilian coastal states. Sixteen PAH were analyzed by gas chromatography, in which 14 PAH were detected, and PAH total concentration (ΣPAH) ranged from 0.25 to 71.60 ng g
MeSH term(s)	Environmental Monitoring/methods ; Brazil ; Plastics ; Polycyclic Aromatic Hydrocarbons/analysis ; Water Pollutants, Chemical/analysis ; Geologic Sediments/chemistry ; Microplastics
Chemical Substances	styrofoam (9003-53-6) ; Plastics ; Polycyclic Aromatic Hydrocarbons ; Water Pollutants, Chemical ; Microplastics
Language	English
Publishing date	2023-11-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-30863-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Bonding stability of universal adhesives to feldspathic ceramic with or without prior silane application.

Cardoso, Gabriela C / Nakanishi, Leina / Isolan, Cristina P / Rodrigues, Camila S / Moraes, Rafael R

Journal of prosthodontics : official journal of the American College of Prosthodontists

2023

Abstract: Purpose: This study aimed to assess the bonding stability of three universal adhesives to a CAD-CAM feldspathic ceramic with or without prior silane application.: Materials and methods: The universal adhesives tested were Ambar Universal (FGM), ... ...

Abstract	Purpose: This study aimed to assess the bonding stability of three universal adhesives to a CAD-CAM feldspathic ceramic with or without prior silane application. Materials and methods: The universal adhesives tested were Ambar Universal (FGM), Single Bond Universal (3M), and Ybond Universal (Yller). Scotchbond Multipurpose Plus (3M) was used as a control. The silane used was RelyX Ceramic Primer (3M). Microtensile bond strength (μTBS) to Vitablocs Mark II was measured after 24 h or 6 months of water aging (n = 20). Failure modes were observed through scanning electron microscopy, and pH and degree of C=C conversion (DC) of the adhesives were measured (n = 3). Data were analyzed using one-, two-, and three-way ANOVA. Results: The pH values differed significantly among the adhesives (p < 0.001), while the DC was similar (p = 0.141). The universal adhesives showed significant differences in μTBS, with higher immediate results when using silane and lower results after aging. Notably, a significant decrease in μTBS was observed after 6 months when silane was applied. In contrast, the control adhesive exhibited consistent results between the 24-h and 6-month storage periods. The universal adhesives showed a decrease in μTBS ranging from 25.5% to 40.1% after prolonged storage. Adhesive failures were predominant in all groups. The presence or absence of silane in the adhesive composition did not affect the bonding performance. Conclusions: The application of a separate silane coupling agent improved the immediate bond strength of universal adhesives to CAD-CAM feldspathic ceramic. However, this bond strength significantly decreased after 6 months of water aging. The bond strength remained stable for universal adhesives when applied without silane after 6 months of aging.
Language	English
Publishing date	2023-09-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1197213-0
ISSN	1532-849X ; 1059-941X
ISSN (online)	1532-849X
ISSN	1059-941X
DOI	10.1111/jopr.13775
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4029: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

Rodrigues, Camila / Percival, Susan S

Nutrients. 2019 Jan. 30, v. 11, no. 2

2019

Abstract: Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H ... 2 ... S), an endogenous, gaseous, signaling transmitter, ... ...

Abstract	Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H<inf>2</inf>S), an endogenous, gaseous, signaling transmitter, has also been shown to be involved in the regulation of inflammation. Recent studies have shown that sulfur-containing compounds from garlic have beneficial effects in attenuating outcomes associated with cardiovascular disease and inflammation by a mechanism that may be related to the H<inf>2</inf>S signaling pathway. In this review, we summarize the main functions of glutathione (GSH), garlic derivatives and H<inf>2</inf>S and their role in the immune response and impact on health and disease.
Keywords	cardiovascular diseases ; garlic ; glutathione ; hydrogen sulfide ; immune response ; immune system ; immunomodulators ; inflammation ; signal transduction
Language	English
Dates of publication	2019-0130
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11020295
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Skeletal Muscle Quality Beyond Average Muscle Attenuation: A Proposal of Skeletal Muscle Phenotypes to Predict Short-Term Survival in Patients With Endometrial Cancer.

Rodrigues, Camila Santos / Chaves, Gabriela Villaça

Journal of the National Comprehensive Cancer Network : JNCCN

2018 Volume 16, Issue 2, Page(s) 153–160

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Aged ; Brazil/epidemiology ; Comorbidity ; Endometrial Neoplasms/complications ; Endometrial Neoplasms/epidemiology ; Endometrial Neoplasms/mortality ; Female ; Humans ; Middle Aged ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/pathology ; Muscle, Skeletal/physiopathology ; Muscular Diseases/diagnosis ; Muscular Diseases/etiology ; Phenotype ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2018-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2250759-0
ISSN	1540-1413 ; 1540-1405
ISSN (online)	1540-1413
ISSN	1540-1405
DOI	10.6004/jnccn.2017.7028
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6365: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Application of essential oils as sanitizer alternatives on the postharvest washing of fresh produce.

Pizzo, Jessica S / Visentainer, Jesui V / da Silva, Andre L B R / Rodrigues, Camila

Food chemistry

2022 Volume 407, Page(s) 135101

Abstract: Growers commonly wash fresh produce with chemical sanitizers during postharvest handling. However, these sanitizers can be harsh to washing systems and pose a health risk to workers. Essential oils (EOs) can be used as alternatives to chemical sanitizers ...

Abstract	Growers commonly wash fresh produce with chemical sanitizers during postharvest handling. However, these sanitizers can be harsh to washing systems and pose a health risk to workers. Essential oils (EOs) can be used as alternatives to chemical sanitizers in produce washing. Previous studies reveal that the EOs from thyme, oregano, cinnamon, and clove are the main EOs evaluated in the studies as potential sanitizers for the washing of produce. The use of EOs and surfactants, such as tween80 and cetylpyridinium chloride, might be used to improve the antimicrobial activity of emulsions. However, studies are still required to evaluate the potential effect of different chemical components of EOs and preparations. Also, it is recommended that researchers focus on overcoming obstacles regarding EOs application in washing systems, including the high levels of EO required to reduce bacterial growth, undesired organoleptic impact on produce, and the poor solubility of EOs in aqueous solution.
Language	English
Publishing date	2022-12-02
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2022.135101
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 3634: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Interface adhesion on layered zirconia: Effects of the veneering ceramic material and veneering technique.

Nogueira, Vanessa de Fátima / Rodrigues, Camila da Silva / Grangeiro, Manassés Tercio Vieira / Contreras, Lisseth Patricia Claudio / Marinho, Renata Marques de Melo / Bottino, Marco Antônio

Journal of prosthodontics : official journal of the American College of Prosthodontists

2023

Abstract: Purpose: To evaluate the effect of different veneering ceramics and veneering techniques on the bond strength to zirconia.: Materials and methods: 3Y-TZP zirconia blocks were sliced into 60 slabs, polished, and sintered. Each slab received one ... ...

Abstract	Purpose: To evaluate the effect of different veneering ceramics and veneering techniques on the bond strength to zirconia. Materials and methods: 3Y-TZP zirconia blocks were sliced into 60 slabs, polished, and sintered. Each slab received one ceramic cylinder (Ø = 3.4 mm, 5 mm-high), according to the veneering ceramic type (feldspathic-FEL or lithium disilicate-based-LD) and the veneering technique (file-splitting with resin-based luting agent-RC, file-splitting with fusion ceramic-FC, or heat-pressing-HT), which resulted in six groups: FEL-RC, FEL-FC, FEL-HT, LD-RC, LD-FC, LD-HT. After preparation, the samples were immersed in distilled water for 24 h before the shear bond strength (SBS) test. The failure modes were classified as adhesive, predominantly adhesive, or cohesive. Representative failure mode images were taken in a Scanning Electron Microscope. The SBS data were analyzed by two-way ANOVA and Tukey's test. Results: Both type of veneering ceramic and technique affected the bond strength. FC led to the highest SBS values. RC and HP provided similar results when compared within each veneering ceramic. Lithium disilicate achieved lower bond strength than feldspathic ceramic when the heat-pressing technique was applied. The most frequent failure modes were predominantly adhesive and adhesive for FEL and LD, respectively. Conclusion: File-splitting with fusion ceramic provided the highest adhesion to zirconia when feldspathic or lithium disilicate-based ceramics were used. The heat-pressing technique for veneering with lithium disilicate significantly decreased the bond strength when compared to the feldspathic ceramic.
Language	English
Publishing date	2023-08-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	1197213-0
ISSN	1532-849X ; 1059-941X
ISSN (online)	1532-849X
ISSN	1059-941X
DOI	10.1111/jopr.13756
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4029: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito