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Article ; Online: Synthesis of temporomandibular disorders management intervention outcomes for development of core outcome sets: A systematic review.

Ferreira, N R / Marto, C M / de Sousa, B M / Loureiro, M / Oliveira, A T / DosSantos, M F / Rodrigues, M J

2024

Abstract: Introduction: The selection of appropriate outcomes in clinical trials and systematic reviews is a crucial factor in determining the results that are useful, reliable, and relevant for both patients and healthcare professionals. Clinicians and ... ...

Abstract	Introduction: The selection of appropriate outcomes in clinical trials and systematic reviews is a crucial factor in determining the results that are useful, reliable, and relevant for both patients and healthcare professionals. Clinicians and researchers have been encouraged to develop and apply core outcome sets (COS) to minimise the discrepancy between studies. Aim: This systematic review is the first phase of the COS development project for clinical trials in temporomandibular disorders (COS-TMD). It aims to identify and synthesise the outcomes used in the randomised controlled trials (RCT) that evaluated the effectiveness of interventions used in TMD management. Materials and methods: An electronic search was performed in several databases: MEDLINE (via PubMed), Scopus, Web of Science, Cochrane Library and EMBASE. The eligibility criteria comprised RCT that applied any intervention to treat temporomandibular joint disorders or masticatory muscle disorders. The identified outcomes were categorised according to domains of the Initiative on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT). Results: The electronic search resulted in 1606 studies. After removing duplicates and applying the eligibility criteria, 106 RCT were included. A total of 43 studies evaluated masticatory muscle disorders, 27 evaluated temporomandibular joint disorders, and 36 analysed mixed TMD. Conclusions: The evaluation showed significant variability in the types of outcomes and their measurement instruments. In addition, some domains such as physical and emotional functioning, participant ratings of global improvement and adverse events have been neglected when determining the effectiveness of treatments for TMD.
Language	English
Publishing date	2024-04-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	187079-8
ISSN	1365-2842 ; 0305-182X
ISSN (online)	1365-2842
ISSN	0305-182X
DOI	10.1111/joor.13692
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Zs.A 991: Show issues

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Article ; Online: Genetic landscape of uveal melanoma.

Rodrigues, M J / Stern, M-H

Journal francais d'ophtalmologie

2015 Volume 38, Issue 6, Page(s) 522–525

Abstract: Uveal melanoma is genetically one of the simplest malignant tumors in adults. Initiation of these tumors is dependent of an oncogenic mutation in the GNAQ or GNA11 genes present in almost all cases. The nature of second mutational events is of major ... ...

Abstract	Uveal melanoma is genetically one of the simplest malignant tumors in adults. Initiation of these tumors is dependent of an oncogenic mutation in the GNAQ or GNA11 genes present in almost all cases. The nature of second mutational events is of major interest as it monosomy 3, gain of 8q and BAP1 inactivation are associated with unfavorable prognosis while SF3BI or EIF1AX are of good prognosis. Despite their common lineage, cutaneous and uveal melanomas are distinct diseases, implicating different oncogenic pathways and contrasting mutational landscapes. Even if uveal melanoma is a simple tumor, it is also one of the deadliest tumors in adults. There is a major clinical need for drugs targeting either the downstream pathways of Gαq and Gα11 or the biological cell functions dysregulated by BAP1 loss of function.
MeSH term(s)	Adult ; Cell Transformation, Neoplastic/genetics ; Chromosome Deletion ; Chromosomes, Human, Pair 3/genetics ; Chromosomes, Human, Pair 8/genetics ; DNA Mutational Analysis ; Eukaryotic Initiation Factor-1/genetics ; GTP-Binding Protein alpha Subunits/genetics ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Genetic Predisposition to Disease/genetics ; Humans ; Melanoma/genetics ; Melanoma/mortality ; Melanoma/therapy ; Phosphoproteins/genetics ; Prognosis ; RNA Splicing Factors ; Ribonucleoprotein, U2 Small Nuclear/genetics ; Risk Factors ; Skin Neoplasms/genetics ; Survival Rate ; Tumor Suppressor Proteins/genetics ; Ubiquitin Thiolesterase/genetics ; Uveal Neoplasms/genetics ; Uveal Neoplasms/mortality ; Uveal Neoplasms/therapy
Chemical Substances	BAP1 protein, human ; Eukaryotic Initiation Factor-1 ; GNA11 protein, human ; GTP-Binding Protein alpha Subunits ; Phosphoproteins ; RNA Splicing Factors ; Ribonucleoprotein, U2 Small Nuclear ; SF3B1 protein, human ; Tumor Suppressor Proteins ; eukaryotic peptide initiation factor-1A ; Ubiquitin Thiolesterase (EC 3.4.19.12) ; GTP-Binding Protein alpha Subunits, Gq-G11 (EC 3.6.5.1)
Language	English
Publishing date	2015-05-11
Publishing country	France
Document type	Journal Article
ZDB-ID	426662-6
ISSN	1773-0597 ; 0181-5512
ISSN (online)	1773-0597
ISSN	0181-5512
DOI	10.1016/j.jfo.2015.04.004
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Zs.A 1417: Show issues

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Article ; Conference proceedings: Exploring seeds of Tamarix africana Poir as a source of bioactive natural products

Martins, C / Castaneda-Loaiza, V / Pereira, C / Rodrigues, M J / Custódio, L

Planta Medica

2022 Volume 88, Issue 15

Event/congress	GA - 70th Annual Meeting 2022, Thessaloniki, Greece, 2022-08-28
Language	English
Publishing date	2022-12-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	123545-x
ISSN	1439-0221 ; 0032-0943
ISSN (online)	1439-0221
ISSN	0032-0943
DOI	10.1055/s-0042-1759227
Database	Thieme publisher's database

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Article ; Conference proceedings: Exploring the biotechnological value of Corema album leaves

Fernandes, E / Correia, H / Rodrigues, M J / Castañeda-Loaiza, V / Pereira, C / Custódio, L

Planta Medica

2022 Volume 88, Issue 15

Event/congress	GA - 70th Annual Meeting 2022, Thessaloniki, Greece, 2022-08-28
Language	English
Publishing date	2022-12-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	123545-x
ISSN	1439-0221 ; 0032-0943
ISSN (online)	1439-0221
ISSN	0032-0943
DOI	10.1055/s-0042-1759191
Database	Thieme publisher's database

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Article ; Online: Development of clinical practice guidelines for allied health and nursing assessment and management of Duchenne muscular dystrophy.

Davidson, Z E / Bray, P / Rose, K / Rodrigues, M J / Corben, L / North, K N / Ryan, M M / Burns, J

Disability and rehabilitation

2021 Volume 44, Issue 19, Page(s) 5450–5467

Abstract: Purpose: To provide evidence-based guidance specific to allied health and nursing practice for the assessment and management of individuals with Duchenne muscular dystrophy (DMD).: Materials and methods: Thirteen key focus areas were identified in ... ...

Abstract	Purpose: To provide evidence-based guidance specific to allied health and nursing practice for the assessment and management of individuals with Duchenne muscular dystrophy (DMD). Materials and methods: Thirteen key focus areas were identified in consultation with health professionals and consumer advocacy groups. A series of systematic literature reviews were conducted to identify assessment and management strategies for each key focus area. A consensus process using modified Delphi methodology, including an Australia-New Zealand expert consensus meeting, was conducted. Recommendations underwent consultative review with key groups before being finalised and prepared for dissemination. Results: This clinical practice guideline (CPG) generated 19 evidence-based recommendations, 117 consensus-based recommendations and five research recommendations across the 13 focus areas to inform allied health assessment and management of individuals with DMD. Conclusions: The resulting recommendations can be used in conjunction with existing medical CPGs to improve, standardise and advocate for allied health and rehabilitation care in DMD. The process used here may be useful for the development of CPGs in other rare diseases.Implications for rehabilitationImplementation-ready evidence-based statements to guide clinical care of individuals with DMD are provided with the potential to improve participation, function in the community and quality of life.A model for developing best practice statements for other rare neurological diseases is described.Allied health and nursing health professionals should focus research efforts to generate quality evidence to support rehabilitation practice.
MeSH term(s)	Consensus ; Health Personnel ; Humans ; Muscular Dystrophy, Duchenne/diagnosis ; Muscular Dystrophy, Duchenne/therapy ; Nursing Assessment ; Quality of Life ; Rare Diseases
Language	English
Publishing date	2021-06-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1104775-6
ISSN	1464-5165 ; 0963-8288
ISSN (online)	1464-5165
ISSN	0963-8288
DOI	10.1080/09638288.2021.1936221
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Zs.A 1569: Show issues

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Article: Comunicação social ou pública?

Rodrigues, M J

Cadernos de saude publica

2004 Volume 10, Issue 3, Page(s) 398–399

Language	Portuguese
Publishing date	2004-01-27
Publishing country	Brazil
Document type	Letter
ZDB-ID	1115730-6
ISSN	1678-4464 ; 0102-311X
ISSN (online)	1678-4464
ISSN	0102-311X
DOI	10.1590/s0102-311x1994000300020
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Zs.A 4981: Show issues

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Article: Coupling sea lavender (Limonium algarvense Erben) and green tea (Camellia sinensis (L.) Kuntze) to produce an innovative herbal beverage with enhanced enzymatic inhibitory properties

Rodrigues, M.J / A. Ovelheiro / C.A. Pereira / J. Varela / J.M.F. Nogueira / L. Barreira / L. Custódio / M. Oliveira / N.R. Neng / V. Neves

South African Association of Botanists South African journal of botany. 2019 Jan., v. 120

2019

Abstract: Herbal beverages containing mixtures of L. algarvense (LA) flowers and C. sinensis (CS) were prepared and their inhibitory properties towards enzymes related with Alzheimer's (acetyl- and butyrylcholinesterase) and Type-2 diabetes mellitus (α-amylase and ...

Abstract	Herbal beverages containing mixtures of L. algarvense (LA) flowers and C. sinensis (CS) were prepared and their inhibitory properties towards enzymes related with Alzheimer's (acetyl- and butyrylcholinesterase) and Type-2 diabetes mellitus (α-amylase and α-glucosidase) were evaluated for the first time. Samples were also appraised for antioxidant capacity and phenolic contents by high-performance liquid chromatography with diode-array detection (HPLC-DAD). Both synergistic and antagonistic interactions were observed: LA samples (infusion: IC50=0.22mg/mL; decoction: 0.39mg/mL) had higher acetylcholinesterase inhibition than CS and mixtures resulted in stronger enzymatic inhibition. CS had the highest rat α-glucosidase inhibition (infusion: IC50=3.91mg/mL; decoction: IC50=2.50mg/mL), which decreased when combined with LA. LA and CS samples had strong antioxidant activity, whereas LA and CS mixtures exhibited higher OH radical-scavenging (0.56≤SE≤1.07) and anti-lipid peroxidation capacity (0.39≤SE≤0.81). CS had higher phenolic contents (infusion: 209mg/g DW; decoction: 169mg/g DW) and its combination with LA increased the phenolic diversity of the mixtures. Our results indicate that LA and CS infusions and decoctions and their combinations have relevant in vitro neuroprotective, antidiabetic and antioxidant properties and could be further explored as potential innovative functional beverages able to reduce the progression of neurodegenerative diseases and diabetic complications, and to prevent oxidative stress and lipid oxidation related diseases.
Keywords	acetylcholinesterase ; alpha-amylase ; alpha-glucosidase ; Alzheimer disease ; antioxidant activity ; beverages ; Camellia sinensis ; cholinesterase ; diabetic complications ; enzyme inhibition ; flowers ; green tea ; high performance liquid chromatography ; Limonium ; lipid peroxidation ; neurodegenerative diseases ; noninsulin-dependent diabetes mellitus ; oxidative stress ; rats
Language	English
Dates of publication	2019-01
Size	p. 87-94.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2126918-X
ISSN	0254-6299
ISSN	0254-6299
DOI	10.1016/j.sajb.2017.12.003
Database	NAL-Catalogue (AGRICOLA)

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Article: Flaxseed gum-biopolymers interactions driving rheological behaviour of oropharyngeal dysphagia-oriented products

Vieira, J. M. / Rodrigues, M. J. / Vicente, A. A. / Cunha, R. L. / Andrade, C. C. P. / Santos, T. P. / Okuro, P. K. / Garcia, S. T.

Food hydrocolloids

2021 Volume 111, Issue -, Page(s) 106257

Language	English
Document type	Article
ZDB-ID	742742-6
ISSN	0268-005X
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Lien épidémiologique entre comportement alimentaire et cancer: exemple du cancer colorectal.

Vano, Y-A / Rodrigues, M-J / Schneider, S-M

Bulletin du cancer

2009 Volume 96, Issue 6, Page(s) 647–658

Abstract: One million people worldwide are affected by colorectal cancer (CRC) every year, resulting in 500,000 deaths. Incidence rate varies widely according to areas. It has been much more common in high-income countries. This trend begins to be reversed, with a ...

Title translation	Epidemiological link between eating habits and cancer: the example of colorectal cancer.
Abstract	One million people worldwide are affected by colorectal cancer (CRC) every year, resulting in 500,000 deaths. Incidence rate varies widely according to areas. It has been much more common in high-income countries. This trend begins to be reversed, with a stabilization of incidence rates in high-income countries and a dramatic increase in developing regions. CRC increase seems to overlap with the increasing level of urbanization in the latter. In the eighties, Doll and Peto already reported that 80% of cancer mortality was avoidable, particularly for CRC for which environmental influence is dominating. Observational studies have reported that migrants tended to reach similar CRC incidence levels that those of natives in the host country. An estimated 60% drop of all CRC cases could be obtained provided eating habits are modified, since these seem to be the main cause of incidence variations. Over the last ten years, many epidemiological studies and meta-analyses have been conducted. However, this abundant literature gave contradictory results. Therefore, in 1997, two groups of experts: the World Cancer Research Fund (WCRF) and the American Institute of Cancer Research (AICR), considered drafting a report on the correlation between diet and cancer a necessity. This systematic literature review, updated in 2007, established that red meat, processed meat and alcohol increase the risk of CRC. Conversely fibers, milk and calcium probably protect against CRC. Considering the most important prospective studies, randomised trials and the 2nd WCRF's report, our article aims at reviewing the evidences about diet and CRC.
MeSH term(s)	Alcohol Drinking/adverse effects ; Animals ; Calcium, Dietary/therapeutic use ; Cattle ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/etiology ; Colorectal Neoplasms/prevention & control ; Dairy Products ; Developed Countries ; Developing Countries ; Feeding Behavior ; Fruit ; Humans ; Meat/adverse effects ; Vegetables ; Vitamin D/therapeutic use
Chemical Substances	Calcium, Dietary ; Vitamin D (1406-16-2)
Language	French
Publishing date	2009-06
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	213270-9
ISSN	1769-6917 ; 0007-4551
ISSN (online)	1769-6917
ISSN	0007-4551
DOI	10.1684/bdc.2009.0874
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Article: "Sexualidade--afectividade".

Rodrigues, M J

Servir (Lisbon, Portugal)

1993 Volume 41, Issue 3, Page(s) 143–146

Title translation	"Sexuality--emotionality".
MeSH term(s)	Emotions ; Female ; Humans ; Male ; Models, Educational ; Sex Education ; Sexual Behavior/psychology
Language	Portuguese
Publishing date	1993-05
Publishing country	Portugal
Document type	Journal Article
ISSN	0871-2379
ISSN	0871-2379
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